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The map label for this gene is btuE [C]

Identifier: 83593198

GI number: 83593198

Start: 2160405

End: 2160992

Strand: Reverse

Name: btuE [C]

Synonym: Rru_A1863

Alternate gene names: 83593198

Gene position: 2160992-2160405 (Counterclockwise)

Preceding gene: 83593199

Following gene: 83593193

Centisome position: 49.65

GC content: 66.16

Gene sequence:

>588_bases
ATGGAACAGGCGAGCAAGGGATCCGGGGGTGGTGACTGGCTGATACGGGGCGTTTTTTCCCTGGGGCTGGCTCTGGCCAG
CTTCGGCGGACCCGCCAGCGCCCAGGCCGCCGGCGCCCACGACTATAGCTTCCCCGCCATTGATGGCGGAACCCTGCCTT
TGGCCGCCTGGGCCGGACATCCGGTTCTGGTGGTCAATACCGCCTCGGAATGCGGCTTCACCGCCCAATACGAGGGGCTC
GAGGCGCTGTGGAAGGCCTATCGCGCCAAGGGCTTGATCGTGCTTGGCGTGCCCTCCAACGATTTCGGCGGCCAGGAACC
GGGCTCGGCGGCCGAGATCAAGGATTTCTGCGAAAGCACCTTCGCCGTCGATTTCCCGCTGACCGACAAGACCGCGGTGA
GCGGCGCCCGCGCCCATCCCTTCTATGCCTGGGCCAAGGCCAGCCGCCCCGATCTGTCGGCGCCGCGCTGGAACTTCCAC
AAATACCTGATCGCCCCCGACGGCTCGCTGGCCGCCTCGTTCTCGGCCCTGACCGACCCCAAAGACCGCGATCTGACCGA
CGCCATCGATAAGCTGCTGGAGAAATAG

Upstream 100 bases:

>100_bases
CGCGACAAGGCTCGGGTGTTACGCGATAAGGGGTGATCCAAAACCGCCGCTCTCCCCTATCAAAGATCAAGTGGGACACG
CGGCGCGAAGGGATCGGGTT

Downstream 100 bases:

>100_bases
ACCTTTGGCCTGAGTTCTGCGCGTTTTTCGGCCATGGCCGCGACAAGCCGCATTTTGAGCGCGGTTTGTTCGGTGGTCAC
TTCGTTAGCGTGACCAGCCC

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MEQASKGSGGGDWLIRGVFSLGLALASFGGPASAQAAGAHDYSFPAIDGGTLPLAAWAGHPVLVVNTASECGFTAQYEGL
EALWKAYRAKGLIVLGVPSNDFGGQEPGSAAEIKDFCESTFAVDFPLTDKTAVSGARAHPFYAWAKASRPDLSAPRWNFH
KYLIAPDGSLAASFSALTDPKDRDLTDAIDKLLEK

Sequences:

>Translated_195_residues
MEQASKGSGGGDWLIRGVFSLGLALASFGGPASAQAAGAHDYSFPAIDGGTLPLAAWAGHPVLVVNTASECGFTAQYEGL
EALWKAYRAKGLIVLGVPSNDFGGQEPGSAAEIKDFCESTFAVDFPLTDKTAVSGARAHPFYAWAKASRPDLSAPRWNFH
KYLIAPDGSLAASFSALTDPKDRDLTDAIDKLLEK
>Mature_195_residues
MEQASKGSGGGDWLIRGVFSLGLALASFGGPASAQAAGAHDYSFPAIDGGTLPLAAWAGHPVLVVNTASECGFTAQYEGL
EALWKAYRAKGLIVLGVPSNDFGGQEPGSAAEIKDFCESTFAVDFPLTDKTAVSGARAHPFYAWAKASRPDLSAPRWNFH
KYLIAPDGSLAASFSALTDPKDRDLTDAIDKLLEK

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=138, Percent_Identity=41.304347826087, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI75709200, Length=150, Percent_Identity=35.3333333333333, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI90903240, Length=150, Percent_Identity=35.3333333333333, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI6006001, Length=152, Percent_Identity=36.1842105263158, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI4557629, Length=188, Percent_Identity=31.9148936170213, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI192455698, Length=133, Percent_Identity=35.3383458646617, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI90903238, Length=132, Percent_Identity=37.1212121212121, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI33186887, Length=139, Percent_Identity=35.2517985611511, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI41406084, Length=164, Percent_Identity=29.8780487804878, Blast_Score=67, Evalue=8e-12,
Organism=Escherichia coli, GI1788003, Length=171, Percent_Identity=38.0116959064327, Blast_Score=118, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17506887, Length=158, Percent_Identity=32.2784810126582, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17535473, Length=149, Percent_Identity=34.8993288590604, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71993584, Length=157, Percent_Identity=34.3949044585987, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193210707, Length=163, Percent_Identity=32.5153374233129, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319721, Length=150, Percent_Identity=40.6666666666667, Blast_Score=129, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=38.9937106918239, Blast_Score=128, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6322826, Length=159, Percent_Identity=34.5911949685535, Blast_Score=115, Evalue=6e-27,
Organism=Drosophila melanogaster, GI85726443, Length=147, Percent_Identity=38.0952380952381, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24656777, Length=163, Percent_Identity=33.1288343558282, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24656767, Length=163, Percent_Identity=33.1288343558282, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24656772, Length=163, Percent_Identity=33.1288343558282, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 20450; Mature: 20450

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQASKGSGGGDWLIRGVFSLGLALASFGGPASAQAAGAHDYSFPAIDGGTLPLAAWAGH
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCC
PVLVVNTASECGFTAQYEGLEALWKAYRAKGLIVLGVPSNDFGGQEPGSAAEIKDFCEST
CEEEEECCHHCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH
FAVDFPLTDKTAVSGARAHPFYAWAKASRPDLSAPRWNFHKYLIAPDGSLAASFSALTDP
EEEECCCCCCHHCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCC
KDRDLTDAIDKLLEK
CCCCHHHHHHHHHCC
>Mature Secondary Structure
MEQASKGSGGGDWLIRGVFSLGLALASFGGPASAQAAGAHDYSFPAIDGGTLPLAAWAGH
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCC
PVLVVNTASECGFTAQYEGLEALWKAYRAKGLIVLGVPSNDFGGQEPGSAAEIKDFCEST
CEEEEECCHHCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH
FAVDFPLTDKTAVSGARAHPFYAWAKASRPDLSAPRWNFHKYLIAPDGSLAASFSALTDP
EEEECCCCCCHHCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCC
KDRDLTDAIDKLLEK
CCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]