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The map label for this gene is era [H]

Identifier: 83593186

GI number: 83593186

Start: 2149790

End: 2150719

Strand: Reverse

Name: era [H]

Synonym: Rru_A1851

Alternate gene names: 83593186

Gene position: 2150719-2149790 (Counterclockwise)

Preceding gene: 83593187

Following gene: 83593185

Centisome position: 49.41

GC content: 64.73

Gene sequence:

>930_bases
ATGACCGATTTGGATTGCCCTTCCCCCGCCGACTCTGCTCCGCCGCGCTGCGGCTTCGTCGCCGTCATCGGCGCCCCCAA
CGCCGGCAAGAGCACTTTGGTGAACCGACTGGTCGGTTCCAAGGTGACCATCGTTTCGCCCAAGGTGCAGACGACGCGCT
CGCGGGTGCGCGGCATCGCCATGGTTGGCGAAGCCCAGGTGGTGTTCGTCGATACCCCGGGAATCTTCCAGCCGCGCAAG
CGCTTCGATCGCGCCATGGTCGCCGCCGCCTGGGAAGGCGCCCTGGAAGCCGATCTGGTGTTGCTGGTGATCGATGCCCA
TAAGGGCATCACGGCCGAGGTCGAAGAGATCCTGACCAAGCTGAAAGCCACCGGCCGCCGGGCCCTTCTGGCGCTCAACA
AGGTCGATGCCCTGGAACGCTCGCGCCTGCTTGAAATGGCCTCGCGCCTGGATGCGGCTTTGCCCTTTGAAAAAGTCTTC
ATGATTTCGGCGCTGACCGGCAGCGGCTGCGACGACGTGTTGGCATGGTTGGCCGAGCGGGTGCCCGCCGGCCCGTGGAT
GTTCCCCGAGGACGAGGTCTCCGATCTGCCCCAGCGTTTGCTGGCCGCCGAGATCACCCGCGAAAAGGTCTTCTTGCAGT
TGCACGAGGAACTGCCCTATGCCGCCGCGGTGGTGACCGAATCCTGGCGCGAGCGCGCCGATGGTTCGGTGCGCATCGAC
CAGACGGTGCTGGTGCAGCGCGAAAGCCAGCGGGCGATTTTCCTCGGCAAGGGCGGCGCGCGGATCAAGGCCCTGGGCAG
GGCCGCCCGCGTGGAGCTTTCCGAGATTTTGGAACGCCCGGTGCATCTGTTCCTTCACGTCAAGGTCAACGACCGGCTGT
GGGACGATCGCGACCAGTATTCCGAATGGGGACTTGATTTCGATGTCTGA

Upstream 100 bases:

>100_bases
CGTCTTCGGGGGCCATCGCGCTATCGCCGGGCCGCTAAAGCCTGAAAGGGATGGGCGAATCGCGCCGAACCCGCGCCAAG
CCAAGAGAAAAAAAGACGAC

Downstream 100 bases:

>100_bases
GCGGGGCGCGCGGTGAGCGGCGGCCTTAATCCCCTGGGGCTGGTTTTGCTGACGGCCGGAGTGGCGCAGTTCCTGGTGCT
GGGCGGCCGCGCCCAAAGCC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTDLDCPSPADSAPPRCGFVAVIGAPNAGKSTLVNRLVGSKVTIVSPKVQTTRSRVRGIAMVGEAQVVFVDTPGIFQPRK
RFDRAMVAAAWEGALEADLVLLVIDAHKGITAEVEEILTKLKATGRRALLALNKVDALERSRLLEMASRLDAALPFEKVF
MISALTGSGCDDVLAWLAERVPAGPWMFPEDEVSDLPQRLLAAEITREKVFLQLHEELPYAAAVVTESWRERADGSVRID
QTVLVQRESQRAIFLGKGGARIKALGRAARVELSEILERPVHLFLHVKVNDRLWDDRDQYSEWGLDFDV

Sequences:

>Translated_309_residues
MTDLDCPSPADSAPPRCGFVAVIGAPNAGKSTLVNRLVGSKVTIVSPKVQTTRSRVRGIAMVGEAQVVFVDTPGIFQPRK
RFDRAMVAAAWEGALEADLVLLVIDAHKGITAEVEEILTKLKATGRRALLALNKVDALERSRLLEMASRLDAALPFEKVF
MISALTGSGCDDVLAWLAERVPAGPWMFPEDEVSDLPQRLLAAEITREKVFLQLHEELPYAAAVVTESWRERADGSVRID
QTVLVQRESQRAIFLGKGGARIKALGRAARVELSEILERPVHLFLHVKVNDRLWDDRDQYSEWGLDFDV
>Mature_308_residues
TDLDCPSPADSAPPRCGFVAVIGAPNAGKSTLVNRLVGSKVTIVSPKVQTTRSRVRGIAMVGEAQVVFVDTPGIFQPRKR
FDRAMVAAAWEGALEADLVLLVIDAHKGITAEVEEILTKLKATGRRALLALNKVDALERSRLLEMASRLDAALPFEKVFM
ISALTGSGCDDVLAWLAERVPAGPWMFPEDEVSDLPQRLLAAEITREKVFLQLHEELPYAAAVVTESWRERADGSVRIDQ
TVLVQRESQRAIFLGKGGARIKALGRAARVELSEILERPVHLFLHVKVNDRLWDDRDQYSEWGLDFDV

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=322, Percent_Identity=28.5714285714286, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1788919, Length=282, Percent_Identity=40.0709219858156, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI87082120, Length=170, Percent_Identity=32.3529411764706, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=233, Percent_Identity=24.4635193133047, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646434, Length=321, Percent_Identity=28.3489096573209, Blast_Score=112, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34088; Mature: 33956

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLDCPSPADSAPPRCGFVAVIGAPNAGKSTLVNRLVGSKVTIVSPKVQTTRSRVRGIA
CCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHEEE
MVGEAQVVFVDTPGIFQPRKRFDRAMVAAAWEGALEADLVLLVIDAHKGITAEVEEILTK
EECCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHH
LKATGRRALLALNKVDALERSRLLEMASRLDAALPFEKVFMISALTGSGCDDVLAWLAER
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEHCCCCCCHHHHHHHHHHH
VPAGPWMFPEDEVSDLPQRLLAAEITREKVFLQLHEELPYAAAVVTESWRERADGSVRID
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEC
QTVLVQRESQRAIFLGKGGARIKALGRAARVELSEILERPVHLFLHVKVNDRLWDDRDQY
CEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCHHHH
SEWGLDFDV
HHCCCCCCC
>Mature Secondary Structure 
TDLDCPSPADSAPPRCGFVAVIGAPNAGKSTLVNRLVGSKVTIVSPKVQTTRSRVRGIA
CCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHEEE
MVGEAQVVFVDTPGIFQPRKRFDRAMVAAAWEGALEADLVLLVIDAHKGITAEVEEILTK
EECCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHH
LKATGRRALLALNKVDALERSRLLEMASRLDAALPFEKVFMISALTGSGCDDVLAWLAER
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEHCCCCCCHHHHHHHHHHH
VPAGPWMFPEDEVSDLPQRLLAAEITREKVFLQLHEELPYAAAVVTESWRERADGSVRID
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEC
QTVLVQRESQRAIFLGKGGARIKALGRAARVELSEILERPVHLFLHVKVNDRLWDDRDQY
CEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCHHHH
SEWGLDFDV
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]