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The map label for this gene is hsaB [H]

Identifier: 83593176

GI number: 83593176

Start: 2140357

End: 2140842

Strand: Reverse

Name: hsaB [H]

Synonym: Rru_A1841

Alternate gene names: 83593176

Gene position: 2140842-2140357 (Counterclockwise)

Preceding gene: 83593183

Following gene: 83593174

Centisome position: 49.18

GC content: 62.76

Gene sequence:

>486_bases
ATGCCCTTCGACGACCGCGCATTCCGCAAAGCCCTTGGTTGTTTCGCCTCCGGGGTGACGGTCATCACCACCCTCGATGC
CGCCCAGCGGCCGGTGGGGGTGACCGTCAGCGCCTTTTCCTCTCTCTCGCTCGACCCGCCCATGGTACTGTTTTGCCTTG
GAAAATCCACCAGTAACCTTGAGGCGTTCCGTCAGGGGCCGGTCAGCATTTCCATATTGGCCGAGGGGCAACAGGATCTG
TCGATTCGTTTCGCCAGCCGGGGGGTCGATAAATTCGCCGGGCTCGAGATGGATACCGCCCCGGGCGGCGTTCCCGCCCC
CAAGGATGTCTTGGCGCGGCTCGACTGCGTCATCACCCAGACCATCGAGGGCGGGGATCATCTGATCGTGCTCTGCGCGG
TCGAGGATCTTATCACCCGCACCGGTGGCCAACCCTTGGTCTATTTCCGGGGCAGCTATACCCAAGTCGGCGTGCTACCC
GTCTGA

Upstream 100 bases:

>100_bases
AGGCGGAAATATCCCCAAAAATCGCCCGGGGTTTGCCATTTCCGCCGGTCAGGCCCAAATAATCCCGAACGTCCCTGTTC
ATTCAGATCCGGAGTCCTCC

Downstream 100 bases:

>100_bases
CCACAGGCGGGGCGGCCGCCCTCTTTAGCGGTCGCCCACCGGTTCGAGGATGAGATGGCCGCCCGAGGGGTCGGCGCCAT
CGACGGTGATCAGCGCGCCG

Product: flavin reductase-like, FMN-binding

Products: NAD(+); reduced flavin [C]

Alternate protein names: Flavin:NADH reductase [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MPFDDRAFRKALGCFASGVTVITTLDAAQRPVGVTVSAFSSLSLDPPMVLFCLGKSTSNLEAFRQGPVSISILAEGQQDL
SIRFASRGVDKFAGLEMDTAPGGVPAPKDVLARLDCVITQTIEGGDHLIVLCAVEDLITRTGGQPLVYFRGSYTQVGVLP
V

Sequences:

>Translated_161_residues
MPFDDRAFRKALGCFASGVTVITTLDAAQRPVGVTVSAFSSLSLDPPMVLFCLGKSTSNLEAFRQGPVSISILAEGQQDL
SIRFASRGVDKFAGLEMDTAPGGVPAPKDVLARLDCVITQTIEGGDHLIVLCAVEDLITRTGGQPLVYFRGSYTQVGVLP
V
>Mature_160_residues
PFDDRAFRKALGCFASGVTVITTLDAAQRPVGVTVSAFSSLSLDPPMVLFCLGKSTSNLEAFRQGPVSISILAEGQQDLS
IRFASRGVDKFAGLEMDTAPGGVPAPKDVLARLDCVITQTIEGGDHLIVLCAVEDLITRTGGQPLVYFRGSYTQVGVLPV

Specific function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the non-flavoprotein flavin reductase family [H]

Homologues:

Organism=Escherichia coli, GI87081819, Length=153, Percent_Identity=33.9869281045752, Blast_Score=85, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct [H]

EC number: 1.6.8.- [C]

Molecular weight: Translated: 17004; Mature: 16873

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFDDRAFRKALGCFASGVTVITTLDAAQRPVGVTVSAFSSLSLDPPMVLFCLGKSTSNL
CCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEHHCCCCCCCCEEEEEECCCCCCH
EAFRQGPVSISILAEGQQDLSIRFASRGVDKFAGLEMDTAPGGVPAPKDVLARLDCVITQ
HHHHCCCEEEEEEECCCCCEEEEEECCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHEEE
TIEGGDHLIVLCAVEDLITRTGGQPLVYFRGSYTQVGVLPV
EECCCCEEEEEEEHHHHHHHCCCCEEEEEECCCEEEEEECC
>Mature Secondary Structure 
PFDDRAFRKALGCFASGVTVITTLDAAQRPVGVTVSAFSSLSLDPPMVLFCLGKSTSNL
CCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEHHCCCCCCCCEEEEEECCCCCCH
EAFRQGPVSISILAEGQQDLSIRFASRGVDKFAGLEMDTAPGGVPAPKDVLARLDCVITQ
HHHHCCCEEEEEEECCCCCEEEEEECCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHEEE
TIEGGDHLIVLCAVEDLITRTGGQPLVYFRGSYTQVGVLPV
EECCCCEEEEEEEHHHHHHHCCCCEEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; flavin [C]

Specific reaction: NADH + flavin = NAD(+) + reduced flavin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA