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The map label for this gene is uppP2

Identifier: 83593138

GI number: 83593138

Start: 2097178

End: 2098002

Strand: Reverse

Name: uppP2

Synonym: Rru_A1803

Alternate gene names: 83593138

Gene position: 2098002-2097178 (Counterclockwise)

Preceding gene: 83593140

Following gene: 83593137

Centisome position: 48.2

GC content: 62.42

Gene sequence:

>825_bases
ATGGATCTCGTAATGCTGATCAAGGCCGCCATCCTTGGTCTTGTCGAGGGGATAACCGAGTTCCTGCCGATTTCGAGCAC
CGGCCATCTGATTATCGCCGGCAGCCTGCTCGATTTCCTTGATGAACAAAAACGCGACGTTTTCGTCATCGTCATCCAGC
TCGGCGCCATCCTGGCGGTGTGCTGGGAATACCGGCGGCGACTGACCGATGTGGTGGCCGGGCTGGGCAGTGATCCCCAA
TCGTGGAAATTCGTCACCAATCTGCTGATCGCCTTCCTGCCCGCCGTGGTTTTGGGGCTGACCTTCGGCAAGGCGATCAA
GGCCCATTTGTTTTCGCCCGTGCCCGTGGCCACGGCCTTCATCGTCGGTGGTCTGGTCATTCTGTGGGCCGAGCGCCGGC
GCCATCCGATCCGGGTGCGCGAGGTCGACGAGATGACCTGGGTCGATGCCCTGAAGATCGGCCTCGCCCAATGCTTCGCC
CTGATCCCGGGCACCTCGCGCTCGGGGGCGACGATCATCGGCGGTTTGTTCTTCGGCCTGTCGCGCAAGGCGGCGACCGA
GTTCTCGTTCTTCCTGGCGATCCCGACGCTGACGGCGGCCTCGCTCTATGACCTCTATAAGAACCGCGCCCTCTTGGATG
GCGATATGAGCGGCCTGATGGCGGTGGGGTTTGTCGTTTCCTTCCTCAGCGCCCTGGTCGCCGTGCGCGGTCTGATCCGC
TACATCTCGCGTCACGACTTCACGGTCTTTGCCTGGTATCGCATCGCCTTTGGTCTGGTGGTCTTGGCGACCGCCTGGTC
CGGGCTGGTGTCGTGGAGCGCGTGA

Upstream 100 bases:

>100_bases
CGCAAGAAGGGGGTGGCAGAGAACGGCGTTTTGGGGGAAGAATGCCGGCCGTCGGCGGCCGCGAGGGCGCCGTTTTTCAC
AAGCGGAAAGGCGCGATCGA

Downstream 100 bases:

>100_bases
GGGAAGGGGCGGGGACGAGAAGTCCCCGCCCGCCGACGCCCGGAACGAGGATTTCACGGCCTGCATGGCGGTTTTACCAA
GGCGCAATGAACTTCTCTCG

Product: undecaprenyl-diphosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 2; Undecaprenyl pyrophosphate phosphatase 2

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MDLVMLIKAAILGLVEGITEFLPISSTGHLIIAGSLLDFLDEQKRDVFVIVIQLGAILAVCWEYRRRLTDVVAGLGSDPQ
SWKFVTNLLIAFLPAVVLGLTFGKAIKAHLFSPVPVATAFIVGGLVILWAERRRHPIRVREVDEMTWVDALKIGLAQCFA
LIPGTSRSGATIIGGLFFGLSRKAATEFSFFLAIPTLTAASLYDLYKNRALLDGDMSGLMAVGFVVSFLSALVAVRGLIR
YISRHDFTVFAWYRIAFGLVVLATAWSGLVSWSA

Sequences:

>Translated_274_residues
MDLVMLIKAAILGLVEGITEFLPISSTGHLIIAGSLLDFLDEQKRDVFVIVIQLGAILAVCWEYRRRLTDVVAGLGSDPQ
SWKFVTNLLIAFLPAVVLGLTFGKAIKAHLFSPVPVATAFIVGGLVILWAERRRHPIRVREVDEMTWVDALKIGLAQCFA
LIPGTSRSGATIIGGLFFGLSRKAATEFSFFLAIPTLTAASLYDLYKNRALLDGDMSGLMAVGFVVSFLSALVAVRGLIR
YISRHDFTVFAWYRIAFGLVVLATAWSGLVSWSA
>Mature_274_residues
MDLVMLIKAAILGLVEGITEFLPISSTGHLIIAGSLLDFLDEQKRDVFVIVIQLGAILAVCWEYRRRLTDVVAGLGSDPQ
SWKFVTNLLIAFLPAVVLGLTFGKAIKAHLFSPVPVATAFIVGGLVILWAERRRHPIRVREVDEMTWVDALKIGLAQCFA
LIPGTSRSGATIIGGLFFGLSRKAATEFSFFLAIPTLTAASLYDLYKNRALLDGDMSGLMAVGFVVSFLSALVAVRGLIR
YISRHDFTVFAWYRIAFGLVVLATAWSGLVSWSA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=262, Percent_Identity=45.8015267175573, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP2_RHORT (Q2RTE2)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426890.1
- STRING:   Q2RTE2
- GeneID:   3835227
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1803
- NMPDR:   fig|1085.1.peg.2377
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   LVQCLAM
- PhylomeDB:   Q2RTE2
- ProtClustDB:   CLSK2773231
- BioCyc:   RRUB269796:RRU_A1803-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29879; Mature: 29879

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf7155b8)-; HASH(0xf743824)-; HASH(0xfb05780)-; HASH(0xfb00858)-; HASH(0xcceca80)-; HASH(0xef87f30)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure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HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA