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The map label for this gene is argS

Identifier: 83593114

GI number: 83593114

Start: 2070080

End: 2071858

Strand: Reverse

Name: argS

Synonym: Rru_A1779

Alternate gene names: 83593114

Gene position: 2071858-2070080 (Counterclockwise)

Preceding gene: 83593115

Following gene: 83593113

Centisome position: 47.6

GC content: 65.71

Gene sequence:

>1779_bases
ATGAACGTTTTTCACGACATAAAAGAAACCGTCCTGGCGCAGGTCGCCGCCCTCCAGGCCGAGGGGCGCCTGCCCGAAGG
CCTGGAGACCGGACGGGTGGCCGTGGAGCCGCCGCGCGAGGCCGCCCATGGCGACATGGCGACCAATGCCGCGATGGTTC
TGGCCAAGCCCGCCGGTCTGGCGCCGCGCGCCGTCGCCGAGATGCTGGTTGAAAAGCTGGTCGGGGTCGATGGCATCGTC
GCCGCCGAGACGGCCGGCCCGGGGTTCATCAATCTGCGTCTCGATCCAAAGATTTGGCGCAAGACCCTGAAGACGGTTCT
CACCCTGGGCACGGCCTTTGGCGCGTCCACCATGGGGCGGGGCGCGGCGGTCAATGTCGAATTCGTTTCGGCCAATCCGA
CCGGCCCGATGCATGTCGGCCATGGGCGGGGCGCGGTGTTCGGCGATGCCCTGGCCGCCCTGCTGGTCAAGGCCGGCTGG
GCGGTGACCCGGGAATATTATGTCAATGACGCCGGCGCCCAGGTCGATTCCCTGGCACGCGCCCTTTATGCCCGCTACCG
GGTGGCGGTCGGCGATCTCGACGAGGCGGCCTTCGCCGCCATGCTGGCCGCCCGCGAGATCGAATACGGCGGCGATTATC
TGGTGCCGGTGGCCGCCGATATCGCCCAAGCCGATGGCACGCGCTGGACGACGGTCGCCGAGAGCGACTGGCTGCCGGCC
TTCCGCGCCATCGGCATCGAGCGCATGTTGGCGCTGATCAAGGAGGATCTGGCGGCGCTGGGCGTCGTCCATGATGTCTT
CACCTCCGAGCAGGCGCTGGTGCGCGCCGGTCGGGTCGACGAGATGATGACCGATCTGGAAAGCCGCGATCTGGTCTATG
TCGGCACCCTGGAGCCGCCCAAGGGCAAGACCCCCGATGATTGGGAGCCGCGCCCGCAGACCCTGTTCCGCGCCACCGGC
TTTGGCGACGAGGTCGATCGCCCCTTGAAGAAATCCGATGGCAGCTGGACCTATTTCGCCAGCGACATCGCCTATCACCA
CGACAAGTTCAAACGCGGTTTCCTGGGCATGATCAACGTGCTGGGCGCCGATCATGGCGGTTATGTCAAACGGCTGAAGG
CCGCCGTCAAGGCGGTGTCCAACGGCGAGGCCGAGCTCGACGTCAAGCTGGTGCAGTTGGTGAAGCTGCTTGATAACGGC
GAGCCGGTGAAGATGTCCAAGCGCGCGGGCACCTTCATCACCCTGCGCGAGGTCGTTGACGAGGTCGGCAAGGATGTCGT
CCGCTTCATCATGCTGACCCGCAAGAACGACGCGGCGCTGGATTTCGATTACGCCCGGGTGACCGAGAAGACCCGCGACA
ATCCGGTGTTCTATGTTCAATACGCCCATGCCCGGGCCTGTTCGGTGGCCCGCCACGCCGCCCAGACCTTTCCGGGGCGC
GATCTGTCGGCCGCGGCCCTGGCGGCGACCGCCGATCTCGATCTGCTCGACGCCGACGAGGAAATGGCCATGGTCCGCCT
GCTGGCGGGCTGGCCGCGACTGGTTGAAAGCGCCGCCGAGGCCCATGAACCCCATCGCGTGGCGTTCTATCTGGGCGAGG
TGGCGGCGGCCTTCCATGGTTTGTGGAACCGTGGCAACGATAACGCCGAACTGAGATTCCTGCTGCCAACGGATGAAGCC
CGCAGTTTGGCACGACTCGCGCTTGTCCAGGCGGTGGCGTCGGTGATAGCGTCTGGTCTCGAAATCTTCGGAGTTGAACC
GGTAAAGGAGATGCGCTGA

Upstream 100 bases:

>100_bases
GCCACAAAACCGCCCGTGTTGTTTGCGACTACATCGCCGGCATGACCGACCGCTTCGCGCTGGACGAACATGCCAGACTG
TTTGATCCTTCGGTGAAACC

Downstream 100 bases:

>100_bases
TGGTGATTAGGCGCCGACGTCCTGACGGTGGGGAAGACGACATCGATCTTGACGAGCAGCTGCTCAATCTTCTCCCTGAG
GAACTCCGGGACTCCGACGA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MNVFHDIKETVLAQVAALQAEGRLPEGLETGRVAVEPPREAAHGDMATNAAMVLAKPAGLAPRAVAEMLVEKLVGVDGIV
AAETAGPGFINLRLDPKIWRKTLKTVLTLGTAFGASTMGRGAAVNVEFVSANPTGPMHVGHGRGAVFGDALAALLVKAGW
AVTREYYVNDAGAQVDSLARALYARYRVAVGDLDEAAFAAMLAAREIEYGGDYLVPVAADIAQADGTRWTTVAESDWLPA
FRAIGIERMLALIKEDLAALGVVHDVFTSEQALVRAGRVDEMMTDLESRDLVYVGTLEPPKGKTPDDWEPRPQTLFRATG
FGDEVDRPLKKSDGSWTYFASDIAYHHDKFKRGFLGMINVLGADHGGYVKRLKAAVKAVSNGEAELDVKLVQLVKLLDNG
EPVKMSKRAGTFITLREVVDEVGKDVVRFIMLTRKNDAALDFDYARVTEKTRDNPVFYVQYAHARACSVARHAAQTFPGR
DLSAAALAATADLDLLDADEEMAMVRLLAGWPRLVESAAEAHEPHRVAFYLGEVAAAFHGLWNRGNDNAELRFLLPTDEA
RSLARLALVQAVASVIASGLEIFGVEPVKEMR

Sequences:

>Translated_592_residues
MNVFHDIKETVLAQVAALQAEGRLPEGLETGRVAVEPPREAAHGDMATNAAMVLAKPAGLAPRAVAEMLVEKLVGVDGIV
AAETAGPGFINLRLDPKIWRKTLKTVLTLGTAFGASTMGRGAAVNVEFVSANPTGPMHVGHGRGAVFGDALAALLVKAGW
AVTREYYVNDAGAQVDSLARALYARYRVAVGDLDEAAFAAMLAAREIEYGGDYLVPVAADIAQADGTRWTTVAESDWLPA
FRAIGIERMLALIKEDLAALGVVHDVFTSEQALVRAGRVDEMMTDLESRDLVYVGTLEPPKGKTPDDWEPRPQTLFRATG
FGDEVDRPLKKSDGSWTYFASDIAYHHDKFKRGFLGMINVLGADHGGYVKRLKAAVKAVSNGEAELDVKLVQLVKLLDNG
EPVKMSKRAGTFITLREVVDEVGKDVVRFIMLTRKNDAALDFDYARVTEKTRDNPVFYVQYAHARACSVARHAAQTFPGR
DLSAAALAATADLDLLDADEEMAMVRLLAGWPRLVESAAEAHEPHRVAFYLGEVAAAFHGLWNRGNDNAELRFLLPTDEA
RSLARLALVQAVASVIASGLEIFGVEPVKEMR
>Mature_592_residues
MNVFHDIKETVLAQVAALQAEGRLPEGLETGRVAVEPPREAAHGDMATNAAMVLAKPAGLAPRAVAEMLVEKLVGVDGIV
AAETAGPGFINLRLDPKIWRKTLKTVLTLGTAFGASTMGRGAAVNVEFVSANPTGPMHVGHGRGAVFGDALAALLVKAGW
AVTREYYVNDAGAQVDSLARALYARYRVAVGDLDEAAFAAMLAAREIEYGGDYLVPVAADIAQADGTRWTTVAESDWLPA
FRAIGIERMLALIKEDLAALGVVHDVFTSEQALVRAGRVDEMMTDLESRDLVYVGTLEPPKGKTPDDWEPRPQTLFRATG
FGDEVDRPLKKSDGSWTYFASDIAYHHDKFKRGFLGMINVLGADHGGYVKRLKAAVKAVSNGEAELDVKLVQLVKLLDNG
EPVKMSKRAGTFITLREVVDEVGKDVVRFIMLTRKNDAALDFDYARVTEKTRDNPVFYVQYAHARACSVARHAAQTFPGR
DLSAAALAATADLDLLDADEEMAMVRLLAGWPRLVESAAEAHEPHRVAFYLGEVAAAFHGLWNRGNDNAELRFLLPTDEA
RSLARLALVQAVASVIASGLEIFGVEPVKEMR

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=164, Percent_Identity=32.9268292682927, Blast_Score=87, Evalue=5e-17,
Organism=Escherichia coli, GI1788184, Length=152, Percent_Identity=34.2105263157895, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320548, Length=571, Percent_Identity=25.9194395796848, Blast_Score=122, Evalue=2e-28,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_RHORT (Q2RTG6)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426866.1
- ProteinModelPortal:   Q2RTG6
- STRING:   Q2RTG6
- GeneID:   3835201
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1779
- NMPDR:   fig|1085.1.peg.2354
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- BioCyc:   RRUB269796:RRU_A1779-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63984; Mature: 63984

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVFHDIKETVLAQVAALQAEGRLPEGLETGRVAVEPPREAAHGDMATNAAMVLAKPAGL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHCCCHHCCCEEEEECCCCC
APRAVAEMLVEKLVGVDGIVAAETAGPGFINLRLDPKIWRKTLKTVLTLGTAFGASTMGR
CHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCC
GAAVNVEFVSANPTGPMHVGHGRGAVFGDALAALLVKAGWAVTREYYVNDAGAQVDSLAR
CEEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHCHHHHHHHEECCCCCHHHHHHH
ALYARYRVAVGDLDEAAFAAMLAAREIEYGGDYLVPVAADIAQADGTRWTTVAESDWLPA
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCCEEEEECCCCCCHH
FRAIGIERMLALIKEDLAALGVVHDVFTSEQALVRAGRVDEMMTDLESRDLVYVGTLEPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCCEEEEECCCCC
KGKTPDDWEPRPQTLFRATGFGDEVDRPLKKSDGSWTYFASDIAYHHDKFKRGFLGMINV
CCCCCCCCCCCCHHHEEECCCCHHHCCCHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
LGADHGGYVKRLKAAVKAVSNGEAELDVKLVQLVKLLDNGEPVKMSKRAGTFITLREVVD
HCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCEEEHHHHHH
EVGKDVVRFIMLTRKNDAALDFDYARVTEKTRDNPVFYVQYAHARACSVARHAAQTFPGR
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHCCCC
DLSAAALAATADLDLLDADEEMAMVRLLAGWPRLVESAAEAHEPHRVAFYLGEVAAAFHG
CCCHHHHHHHCCCCEECCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
LWNRGNDNAELRFLLPTDEARSLARLALVQAVASVIASGLEIFGVEPVKEMR
HHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCHHEECCCCHHHCC
>Mature Secondary Structure
MNVFHDIKETVLAQVAALQAEGRLPEGLETGRVAVEPPREAAHGDMATNAAMVLAKPAGL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHCCCHHCCCEEEEECCCCC
APRAVAEMLVEKLVGVDGIVAAETAGPGFINLRLDPKIWRKTLKTVLTLGTAFGASTMGR
CHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCC
GAAVNVEFVSANPTGPMHVGHGRGAVFGDALAALLVKAGWAVTREYYVNDAGAQVDSLAR
CEEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHCHHHHHHHEECCCCCHHHHHHH
ALYARYRVAVGDLDEAAFAAMLAAREIEYGGDYLVPVAADIAQADGTRWTTVAESDWLPA
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCCEEEEECCCCCCHH
FRAIGIERMLALIKEDLAALGVVHDVFTSEQALVRAGRVDEMMTDLESRDLVYVGTLEPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCCEEEEECCCCC
KGKTPDDWEPRPQTLFRATGFGDEVDRPLKKSDGSWTYFASDIAYHHDKFKRGFLGMINV
CCCCCCCCCCCCHHHEEECCCCHHHCCCHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
LGADHGGYVKRLKAAVKAVSNGEAELDVKLVQLVKLLDNGEPVKMSKRAGTFITLREVVD
HCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCEEEHHHHHH
EVGKDVVRFIMLTRKNDAALDFDYARVTEKTRDNPVFYVQYAHARACSVARHAAQTFPGR
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHCCCC
DLSAAALAATADLDLLDADEEMAMVRLLAGWPRLVESAAEAHEPHRVAFYLGEVAAAFHG
CCCHHHHHHHCCCCEECCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
LWNRGNDNAELRFLLPTDEARSLARLALVQAVASVIASGLEIFGVEPVKEMR
HHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCHHEECCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA