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The map label for this gene is bdlA [H]

Identifier: 83593047

GI number: 83593047

Start: 2004237

End: 2005739

Strand: Reverse

Name: bdlA [H]

Synonym: Rru_A1712

Alternate gene names: 83593047

Gene position: 2005739-2004237 (Counterclockwise)

Preceding gene: 83593048

Following gene: 83593045

Centisome position: 46.08

GC content: 61.28

Gene sequence:

>1503_bases
ATGGCTTTTAGCATTTTTGGTGGGGGGGCGGCTAACCGATTGACCGCGCTCAGCACATCAATGGCTTTGATCGAATTTGA
CCTGGACGGCACCATTCTTGCGGCGAATACAAACTTTCTTACAGTGATGGGGTATCGACTTGACGAGGTGAGGGGCAAAA
AGCACAGCCTGTTCGTCGAACCCGCCGAACGCGACAGCGCCGAGTATCGCGCCTTCTGGGATCAGTTGCGGCGGGGGACG
TTTCTGGCCAGGGAATTTAAGCGCGTCGGCAAAGGCGGCAAGGAAATCTGGCTGGAGGCGTCTTACAATCCCATCCTGGG
CCTCGGCGGAAAGCCCACTGGCGTTCTCAAGATCGCCACGGATATCACCCGAAAAAAGGCCGAGGCCGTCGAGCTGCAGG
AAAAAGTGGCGGCGATCAGCCGCTCCCAAGCCGTCATCGAATTCGCCATGGACGGCACGATCCTCACCGCCAACGAAAAC
TTCTTGAAAACCATGGGCTATCGCCTTGAGGACATCCAAGGCAAGAACCACAGCCTGTTCATCGCCCCCGGCGAGCGCGA
CAGCGCCGAGTATCGTCAGTTCTGGGATATCCTGCGCCGCGGCGAATTCCAGGCCAGACAATTCATGCGCATCGGCAAGG
GGGGCAGGGTGGTCTGGCTTGAAGCCTCGTATAATCCGATCCTCAACCTTGATGGCAAACCCTATAAGGTGGTGAAGTTC
GCCACCGATATTTCCGGGCGCAAAGAGGAAAACGCCGCCCTGGCCAAGCAATTCGAGACCGGGGTGAAGGCCACGGTTGA
AACGGTGGCCTCATCGGCGGGAAAAATGCAAAACACGGCGCAGGCCATGGCGGCGGCGGCCGAGCAAACCTCGCAGCAAT
CCTCGATCGTTTCGACGGCGGCCGAGGAACTTGGCACCTCGGTCAGCGAGATCGCTCGCCAGATCGCTCAGGCGACGCGG
GTGACCGACGACGCGGTGGCCGAGACCAAGGCCTCGGAAAAGCTGGTGGGCGAGTTGGTCACCGCCGCCGACAAGATCGG
CGCGGTATCCCAATTGATCGCCGACATCGCCAGCCAGACCAATCTTCTGGCGCTCAACGCCACCATCGAGGCCGCCAGGG
CCGGTGACGCCGGCAAGGGCTTCGCCGTCGTCGCCTCGGAAGTGAAATCCCTGGCCAATCAAACCGCCAAGGCGACGGAA
GAGATCGAACAGCAGGTCAGCGGCATTCAGGACTCAAGCCGGGCGACGGCAAGCGCCATCCGCCAGATCGGCTTGGTGAT
CGCCCAGGTCAGCGAAATCAGCGCCTCGATTTCCGGCGCGGCGGAGGAACAGGCCGCCGCCACCCGCGAAGTCTCGCAAA
ACATCAACGGCGTCGAACAGGCGGCGGCGCAAACCGGCCGCTCCTCCACCGAGCTTCTCAGCGTCGCCCAATCGATGTCC
CACCAAGCCGACGACCTGGAAACCCGCGTCGACGCGTTCCTGCGCAAGGTTCGATCGATGTGA

Upstream 100 bases:

>100_bases
TCCAGGGTCGGCAAACATTGAACCTCGTCTTGTTGGGCTATATACTAAATAAGCAGCATCTATCGCGATGTATGCTCAAC
TTGAGGTATGGGGTTCGAGA

Downstream 100 bases:

>100_bases
GGTCGCTCACGGGCGTCCGTTGGCGACCGGGATGCGGGCGATGACCTTGATCTCGAAGTCGAAGCCGGCGAGCCAGGTCA
CGCCGACGGCCGTCCAGTTC

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MAFSIFGGGAANRLTALSTSMALIEFDLDGTILAANTNFLTVMGYRLDEVRGKKHSLFVEPAERDSAEYRAFWDQLRRGT
FLAREFKRVGKGGKEIWLEASYNPILGLGGKPTGVLKIATDITRKKAEAVELQEKVAAISRSQAVIEFAMDGTILTANEN
FLKTMGYRLEDIQGKNHSLFIAPGERDSAEYRQFWDILRRGEFQARQFMRIGKGGRVVWLEASYNPILNLDGKPYKVVKF
ATDISGRKEENAALAKQFETGVKATVETVASSAGKMQNTAQAMAAAAEQTSQQSSIVSTAAEELGTSVSEIARQIAQATR
VTDDAVAETKASEKLVGELVTAADKIGAVSQLIADIASQTNLLALNATIEAARAGDAGKGFAVVASEVKSLANQTAKATE
EIEQQVSGIQDSSRATASAIRQIGLVIAQVSEISASISGAAEEQAAATREVSQNINGVEQAAAQTGRSSTELLSVAQSMS
HQADDLETRVDAFLRKVRSM

Sequences:

>Translated_500_residues
MAFSIFGGGAANRLTALSTSMALIEFDLDGTILAANTNFLTVMGYRLDEVRGKKHSLFVEPAERDSAEYRAFWDQLRRGT
FLAREFKRVGKGGKEIWLEASYNPILGLGGKPTGVLKIATDITRKKAEAVELQEKVAAISRSQAVIEFAMDGTILTANEN
FLKTMGYRLEDIQGKNHSLFIAPGERDSAEYRQFWDILRRGEFQARQFMRIGKGGRVVWLEASYNPILNLDGKPYKVVKF
ATDISGRKEENAALAKQFETGVKATVETVASSAGKMQNTAQAMAAAAEQTSQQSSIVSTAAEELGTSVSEIARQIAQATR
VTDDAVAETKASEKLVGELVTAADKIGAVSQLIADIASQTNLLALNATIEAARAGDAGKGFAVVASEVKSLANQTAKATE
EIEQQVSGIQDSSRATASAIRQIGLVIAQVSEISASISGAAEEQAAATREVSQNINGVEQAAAQTGRSSTELLSVAQSMS
HQADDLETRVDAFLRKVRSM
>Mature_499_residues
AFSIFGGGAANRLTALSTSMALIEFDLDGTILAANTNFLTVMGYRLDEVRGKKHSLFVEPAERDSAEYRAFWDQLRRGTF
LAREFKRVGKGGKEIWLEASYNPILGLGGKPTGVLKIATDITRKKAEAVELQEKVAAISRSQAVIEFAMDGTILTANENF
LKTMGYRLEDIQGKNHSLFIAPGERDSAEYRQFWDILRRGEFQARQFMRIGKGGRVVWLEASYNPILNLDGKPYKVVKFA
TDISGRKEENAALAKQFETGVKATVETVASSAGKMQNTAQAMAAAAEQTSQQSSIVSTAAEELGTSVSEIARQIAQATRV
TDDAVAETKASEKLVGELVTAADKIGAVSQLIADIASQTNLLALNATIEAARAGDAGKGFAVVASEVKSLANQTAKATEE
IEQQVSGIQDSSRATASAIRQIGLVIAQVSEISASISGAAEEQAAATREVSQNINGVEQAAAQTGRSSTELLSVAQSMSH
QADDLETRVDAFLRKVRSM

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=527, Percent_Identity=26.3757115749526, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788194, Length=273, Percent_Identity=32.6007326007326, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787690, Length=261, Percent_Identity=34.0996168582375, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788195, Length=230, Percent_Identity=31.304347826087, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI2367378, Length=176, Percent_Identity=36.9318181818182, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 53629; Mature: 53498

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS01228 COF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFSIFGGGAANRLTALSTSMALIEFDLDGTILAANTNFLTVMGYRLDEVRGKKHSLFVE
CEEEEECCCCHHHHHHHHHCEEEEEECCCCEEEEECCCEEEEECCHHHHHCCCCCEEEEC
PAERDSAEYRAFWDQLRRGTFLAREFKRVGKGGKEIWLEASYNPILGLGGKPTGVLKIAT
CCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCEEEEEHH
DITRKKAEAVELQEKVAAISRSQAVIEFAMDGTILTANENFLKTMGYRLEDIQGKNHSLF
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEECCCHHHHHHCCHHHHCCCCCCEEE
IAPGERDSAEYRQFWDILRRGEFQARQFMRIGKGGRVVWLEASYNPILNLDGKPYKVVKF
EECCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCEEECCCCCEEEEEE
ATDISGRKEENAALAKQFETGVKATVETVASSAGKMQNTAQAMAAAAEQTSQQSSIVSTA
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEELGTSVSEIARQIAQATRVTDDAVAETKASEKLVGELVTAADKIGAVSQLIADIASQT
HHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NLLALNATIEAARAGDAGKGFAVVASEVKSLANQTAKATEEIEQQVSGIQDSSRATASAI
CEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RQIGLVIAQVSEISASISGAAEEQAAATREVSQNINGVEQAAAQTGRSSTELLSVAQSMS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHH
HQADDLETRVDAFLRKVRSM
CCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AFSIFGGGAANRLTALSTSMALIEFDLDGTILAANTNFLTVMGYRLDEVRGKKHSLFVE
EEEEECCCCHHHHHHHHHCEEEEEECCCCEEEEECCCEEEEECCHHHHHCCCCCEEEEC
PAERDSAEYRAFWDQLRRGTFLAREFKRVGKGGKEIWLEASYNPILGLGGKPTGVLKIAT
CCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCEEEEEHH
DITRKKAEAVELQEKVAAISRSQAVIEFAMDGTILTANENFLKTMGYRLEDIQGKNHSLF
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEECCCHHHHHHCCHHHHCCCCCCEEE
IAPGERDSAEYRQFWDILRRGEFQARQFMRIGKGGRVVWLEASYNPILNLDGKPYKVVKF
EECCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCEEECCCCCEEEEEE
ATDISGRKEENAALAKQFETGVKATVETVASSAGKMQNTAQAMAAAAEQTSQQSSIVSTA
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEELGTSVSEIARQIAQATRVTDDAVAETKASEKLVGELVTAADKIGAVSQLIADIASQT
HHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NLLALNATIEAARAGDAGKGFAVVASEVKSLANQTAKATEEIEQQVSGIQDSSRATASAI
CEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RQIGLVIAQVSEISASISGAAEEQAAATREVSQNINGVEQAAAQTGRSSTELLSVAQSMS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHH
HQADDLETRVDAFLRKVRSM
CCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]