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The map label for this gene is clpX

Identifier: 83592886

GI number: 83592886

Start: 1828668

End: 1829936

Strand: Direct

Name: clpX

Synonym: Rru_A1551

Alternate gene names: 83592886

Gene position: 1828668-1829936 (Clockwise)

Preceding gene: 83592885

Following gene: 83592887

Centisome position: 42.01

GC content: 62.41

Gene sequence:

>1269_bases
ATGTCGAAGTCTTCAGGCGGTGATTCGAAGAACACCCTCTACTGCTCATTCTGCGGAAAGAGCCAGCATGAGGTCCGTAA
GCTCATCGCCGGACCGACGGTGTTCATCTGCGACGAATGCGTCGAACTGTGCATGGACATCATCCGCGAGGAGCACAAGA
CCAGTCTGGTGAAGTCCCGCGACGGGGTTCCCTCGCCTAAGGACATCCTCAAGGTTCTCGATGATTATGTGATCGGCCAG
CAGCACGCCAAAAAGGTGCTGTCCGTCGCCGTCCACAATCACTACAAACGGCTGTCCCAGGCCGGCAAGAACAGCGACGT
GGAACTGGCGAAGTCGAACATCTTGCTGATCGGTCCGACCGGTTGCGGCAAGACCCTGCTCGCCCAGACCCTGGCGCGCA
TTCTCGACGTGCCCTTCACCATGGCCGACGCCACGACGCTGACCGAGGCCGGCTATGTCGGCGAGGATGTGGAGAACATC
ATCCTCAAGCTGCTTCAGGCCTCGGATTACAACGTCGAACGCGCCCAGCGCGGCATCGTCTATATCGACGAGATCGACAA
GATCAGCCGCAAGTCCGACAACCCGTCGATCACCCGCGACGTGTCGGGCGAGGGCGTGCAGCAGGCCCTGCTCAAGATCA
TGGAGGGCACCGTCGCCTCGGTGCCGCCCCAGGGCGGGCGCAAGCATCCCCAGCAGGAATTCCTGCAGGTCGACACCACC
AATATCTTGTTCATCTGCGGCGGCGCCTTCGCCGGCCTTGATCGCATCATCTCGGCGCGGGGCAAGGGGTCGTCGATCGG
CTTTGGCGCCGATGTCCGCGATCCCGAAGCCCGGCGCACCGGCGAGGTTCTGCGCGCCGTCGAGCCCGAGGATCTGCTGA
AATACGGCCTGATCCCCGAATTCGTCGGCCGTCTGCCGGTTCTGGCGACCCTGGACGATCTGGACGAAGACGCCCTGGTC
GATATCTTGACCACGCCTAAGAACGCCCTGGTCAAGCAGTATCAGCGCCTGTTCGAGATGGAGAGCACCCAGCTTTCCTT
CAAGGAAGACGCGCTGCGCTGCATCGCGCTGAAGGCCATCGCCCGCAAGACCGGCGCCCGCGGCCTGCGCTCGATCATGG
AGGGCATCTTGCTTGACACCATGTTCGATCTGCCGGGCATGGAAGGCGTCGAGGAGGTGGTGGTCAACAAGGAGGTGGTC
GAAGGCCGGGCCAAGCCTTTGTTCATCTATTCCGACCAGCGCACCTCGGCCGACGGCGCCAGCGCCTGA

Upstream 100 bases:

>100_bases
GGTCCACTGGACGGGGAACCTGGGCTCCCGGCGGAACGGACGGTCAGGTGGACACCCTGGCCCGCGGGTCTGTCGTGGAC
GACGAAGGAGTGCTTTCGAG

Downstream 100 bases:

>100_bases
TATCAGCCACCGGGGCAAAGGGCTCTTCGCCCCGGTGTTCGATTTTGCCCGGCGGTCACGCCAGATCGCCGTGCCAAGGC
CGGCGCCGGTGATCGGCGGC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MSKSSGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTSLVKSRDGVPSPKDILKVLDDYVIGQ
QHAKKVLSVAVHNHYKRLSQAGKNSDVELAKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLDRIISARGKGSSIGFGADVRDPEARRTGEVLRAVEPEDLLKYGLIPEFVGRLPVLATLDDLDEDALV
DILTTPKNALVKQYQRLFEMESTQLSFKEDALRCIALKAIARKTGARGLRSIMEGILLDTMFDLPGMEGVEEVVVNKEVV
EGRAKPLFIYSDQRTSADGASA

Sequences:

>Translated_422_residues
MSKSSGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTSLVKSRDGVPSPKDILKVLDDYVIGQ
QHAKKVLSVAVHNHYKRLSQAGKNSDVELAKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLDRIISARGKGSSIGFGADVRDPEARRTGEVLRAVEPEDLLKYGLIPEFVGRLPVLATLDDLDEDALV
DILTTPKNALVKQYQRLFEMESTQLSFKEDALRCIALKAIARKTGARGLRSIMEGILLDTMFDLPGMEGVEEVVVNKEVV
EGRAKPLFIYSDQRTSADGASA
>Mature_421_residues
SKSSGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTSLVKSRDGVPSPKDILKVLDDYVIGQQ
HAKKVLSVAVHNHYKRLSQAGKNSDVELAKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENII
LKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
ILFICGGAFAGLDRIISARGKGSSIGFGADVRDPEARRTGEVLRAVEPEDLLKYGLIPEFVGRLPVLATLDDLDEDALVD
ILTTPKNALVKQYQRLFEMESTQLSFKEDALRCIALKAIARKTGARGLRSIMEGILLDTMFDLPGMEGVEEVVVNKEVVE
GRAKPLFIYSDQRTSADGASA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=339, Percent_Identity=53.3923303834808, Blast_Score=330, Evalue=1e-90,
Organism=Escherichia coli, GI1786642, Length=405, Percent_Identity=71.8518518518519, Blast_Score=591, Evalue=1e-170,
Organism=Escherichia coli, GI1790366, Length=104, Percent_Identity=41.3461538461538, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=313, Percent_Identity=46.9648562300319, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=313, Percent_Identity=46.9648562300319, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=391, Percent_Identity=37.3401534526854, Blast_Score=242, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=40.4858299595142, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6319704, Length=419, Percent_Identity=38.9021479713604, Blast_Score=259, Evalue=5e-70,
Organism=Drosophila melanogaster, GI24648289, Length=337, Percent_Identity=48.3679525222552, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24648291, Length=337, Percent_Identity=48.3679525222552, Blast_Score=302, Evalue=4e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_RHORT (Q2RU44)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426638.1
- ProteinModelPortal:   Q2RU44
- STRING:   Q2RU44
- GeneID:   3834967
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1551
- NMPDR:   fig|1085.1.peg.2818
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- PhylomeDB:   Q2RU44
- ProtClustDB:   PRK05342
- BioCyc:   RRUB269796:RRU_A1551-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46038; Mature: 45907

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSSGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTSLVKSR
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGVPSPKDILKVLDDYVIGQQHAKKVLSVAVHNHYKRLSQAGKNSDVELAKSNILLIGPT
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEECC
GCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCE
YIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLDRIISARGKGSSIGFGADVRDPEARRTGEVLRAVEPEDLLKYGLIPE
CEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCHH
FVGRLPVLATLDDLDEDALVDILTTPKNALVKQYQRLFEMESTQLSFKEDALRCIALKAI
HHCCCCHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARKTGARGLRSIMEGILLDTMFDLPGMEGVEEVVVNKEVVEGRAKPLFIYSDQRTSADGA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
SA
CC
>Mature Secondary Structure 
SKSSGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTSLVKSR
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGVPSPKDILKVLDDYVIGQQHAKKVLSVAVHNHYKRLSQAGKNSDVELAKSNILLIGPT
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEECC
GCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCE
YIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLDRIISARGKGSSIGFGADVRDPEARRTGEVLRAVEPEDLLKYGLIPE
CEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCHH
FVGRLPVLATLDDLDEDALVDILTTPKNALVKQYQRLFEMESTQLSFKEDALRCIALKAI
HHCCCCHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARKTGARGLRSIMEGILLDTMFDLPGMEGVEEVVVNKEVVEGRAKPLFIYSDQRTSADGA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
SA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA