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The map label for this gene is tig [H]

Identifier: 83592884

GI number: 83592884

Start: 1826024

End: 1827415

Strand: Direct

Name: tig [H]

Synonym: Rru_A1549

Alternate gene names: 83592884

Gene position: 1826024-1827415 (Clockwise)

Preceding gene: 83592883

Following gene: 83592885

Centisome position: 41.95

GC content: 64.3

Gene sequence:

>1392_bases
ATGGCGGGTTTCCGATTATCCACTCGCAAGGTCGTTAGAGAACAGCCGATGCAGGTCACCGAAACCGTCAACGAGTCCCT
CAAGCGGGAATACAAGATCGTCATCCCGGCCGCCGACATCGCCGAGCGGTCCGCCCGGCGGCTGGAGGAGCTGAAGGGTC
AGATGCGCCTGCCCGGCTTCCGCCCCGGCAAGGTCCCGATGTCGATGCTGCGCCAGCGTTTTGGCAAAAGCGTCCTGGGC
GAAGTCCTGGAAAAGGCCGTTCAGGAGTCGATCCGCGAGGTCATGACCAGCCATGAGCTGAAGCCGGCGACCCAGCCCGA
TATCGACCTGATTTCCGAGGTCGAGGAAGGCAAGGACGTCGAATTCACCCTGGCCCTGGAAGTGCTTCCCGAAATCGGCG
AAACCGATTTCTCGGCCCTCGCCCTGGAGCGGGAAGTCGCCGAGGTCGCCGCCGAGAAAATCGAAGAGGCGCTGGAAACC
CTGCGTCAGCAGTCCAAGACCCACGAGCCGGTGACCGATGGTCGCGCCGCGGCCGGTGGCGATCTGGTGGTCATCGATTT
CATCGGCAAGCTTGACGGCGAGGCCTTCGAAGGCGGCAGCGCCGAGGCCTATGATCTGGAACTGGGATCGAATTCGTTCA
TTCCCGGCTTCGAAGACCAGCTGATCGGGGCGACGGCCGGCGAGGCCCGCACCGTGACCGTGAGCTTCCCCGAGGATTAT
CCCGCCGCCCATCTGGCCGGCAAGGAAACCGTCTTCGACGTCACGGTCAAAGAGGTCAAGCAGGCGGTCGTTCCCGAACT
GGACGACGATCTGGCCAAGGCCTTTGGCAAGGAGAGCGCCGAGGCCCTGCGCGAGGCGGTCAAGGCCGACCTTCAGGGCG
AGCTTGACGAGGTCTCCAAGACCAAGCTCAAGCGCAAGCTGCTCGACGCCCTGGCCGATGGCCACGACTTCCCCGTTCCC
CAGACCCTGGTGGACGCCGAGTTCGAGGGGATCTGGGCCCAGATCGAGAAGGCCAAGACCGATGGCCAGCTTGACGAGGA
AGACGCCGCCAAAAGCGACGAGGATCTGCGCGCCGATTACCGCAAGATCGCCGAGCGCCGGGTGCGTCTGGGTCTGTTGC
TCGCCGATGTCGGTCAGCGCGCCCAGGTCACCGTCGCCCAGGAGGACCTCAACAAGGCCCTGATGCGCGAGTTGCGTCGC
TTCCCCGGCCAGGAGGCCGCGGTGATCAACTACTACCGCAACAACCAGCAGGCGATGGACAATCTCCGCGCCCCGGTCTT
CGAGGACAAGGTCTGCGCCCATATCCTGGCTCTGGCCACCGTCACCGACAAGCCGGTCAGCGTCGAGGATCTGATGAAGG
ATCCCGACGAGGACGCCACGCCGACCGCCTAA

Upstream 100 bases:

>100_bases
TCCCAAGGCTTTCAGACCGCCAGGGGTCGCCTTGTCCCGACGGTATTCGTCGCGTTCGCGCGCCCCGTTTCCGCCCCGCT
CCGCTGTCCCGATATAGCGG

Downstream 100 bases:

>100_bases
GCCGCCCGCGGGCGAGAAGGCTTAAAGCCCTTCGTCGCCTCCGGCCTCTGGACAGAGACGGGGCCCAGGTCCTATGTATG
GACCGGGCCCCGTTTTCTTG

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MAGFRLSTRKVVREQPMQVTETVNESLKREYKIVIPAADIAERSARRLEELKGQMRLPGFRPGKVPMSMLRQRFGKSVLG
EVLEKAVQESIREVMTSHELKPATQPDIDLISEVEEGKDVEFTLALEVLPEIGETDFSALALEREVAEVAAEKIEEALET
LRQQSKTHEPVTDGRAAAGGDLVVIDFIGKLDGEAFEGGSAEAYDLELGSNSFIPGFEDQLIGATAGEARTVTVSFPEDY
PAAHLAGKETVFDVTVKEVKQAVVPELDDDLAKAFGKESAEALREAVKADLQGELDEVSKTKLKRKLLDALADGHDFPVP
QTLVDAEFEGIWAQIEKAKTDGQLDEEDAAKSDEDLRADYRKIAERRVRLGLLLADVGQRAQVTVAQEDLNKALMRELRR
FPGQEAAVINYYRNNQQAMDNLRAPVFEDKVCAHILALATVTDKPVSVEDLMKDPDEDATPTA

Sequences:

>Translated_463_residues
MAGFRLSTRKVVREQPMQVTETVNESLKREYKIVIPAADIAERSARRLEELKGQMRLPGFRPGKVPMSMLRQRFGKSVLG
EVLEKAVQESIREVMTSHELKPATQPDIDLISEVEEGKDVEFTLALEVLPEIGETDFSALALEREVAEVAAEKIEEALET
LRQQSKTHEPVTDGRAAAGGDLVVIDFIGKLDGEAFEGGSAEAYDLELGSNSFIPGFEDQLIGATAGEARTVTVSFPEDY
PAAHLAGKETVFDVTVKEVKQAVVPELDDDLAKAFGKESAEALREAVKADLQGELDEVSKTKLKRKLLDALADGHDFPVP
QTLVDAEFEGIWAQIEKAKTDGQLDEEDAAKSDEDLRADYRKIAERRVRLGLLLADVGQRAQVTVAQEDLNKALMRELRR
FPGQEAAVINYYRNNQQAMDNLRAPVFEDKVCAHILALATVTDKPVSVEDLMKDPDEDATPTA
>Mature_462_residues
AGFRLSTRKVVREQPMQVTETVNESLKREYKIVIPAADIAERSARRLEELKGQMRLPGFRPGKVPMSMLRQRFGKSVLGE
VLEKAVQESIREVMTSHELKPATQPDIDLISEVEEGKDVEFTLALEVLPEIGETDFSALALEREVAEVAAEKIEEALETL
RQQSKTHEPVTDGRAAAGGDLVVIDFIGKLDGEAFEGGSAEAYDLELGSNSFIPGFEDQLIGATAGEARTVTVSFPEDYP
AAHLAGKETVFDVTVKEVKQAVVPELDDDLAKAFGKESAEALREAVKADLQGELDEVSKTKLKRKLLDALADGHDFPVPQ
TLVDAEFEGIWAQIEKAKTDGQLDEEDAAKSDEDLRADYRKIAERRVRLGLLLADVGQRAQVTVAQEDLNKALMRELRRF
PGQEAAVINYYRNNQQAMDNLRAPVFEDKVCAHILALATVTDKPVSVEDLMKDPDEDATPTA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=438, Percent_Identity=33.7899543378995, Blast_Score=216, Evalue=2e-57,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 51040; Mature: 50909

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGFRLSTRKVVREQPMQVTETVNESLKREYKIVIPAADIAERSARRLEELKGQMRLPGF
CCCCCCHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCC
RPGKVPMSMLRQRFGKSVLGEVLEKAVQESIREVMTSHELKPATQPDIDLISEVEEGKDV
CCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCC
EFTLALEVLPEIGETDFSALALEREVAEVAAEKIEEALETLRQQSKTHEPVTDGRAAAGG
EEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
DLVVIDFIGKLDGEAFEGGSAEAYDLELGSNSFIPGFEDQLIGATAGEARTVTVSFPEDY
CEEEEEEHHHCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHCCCCCCCCEEEEEECCCCC
PAAHLAGKETVFDVTVKEVKQAVVPELDDDLAKAFGKESAEALREAVKADLQGELDEVSK
CCHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHH
TKLKRKLLDALADGHDFPVPQTLVDAEFEGIWAQIEKAKTDGQLDEEDAAKSDEDLRADY
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHH
RKIAERRVRLGLLLADVGQRAQVTVAQEDLNKALMRELRRFPGQEAAVINYYRNNQQAMD
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCHHHHH
NLRAPVFEDKVCAHILALATVTDKPVSVEDLMKDPDEDATPTA
HHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AGFRLSTRKVVREQPMQVTETVNESLKREYKIVIPAADIAERSARRLEELKGQMRLPGF
CCCCCHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCC
RPGKVPMSMLRQRFGKSVLGEVLEKAVQESIREVMTSHELKPATQPDIDLISEVEEGKDV
CCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCC
EFTLALEVLPEIGETDFSALALEREVAEVAAEKIEEALETLRQQSKTHEPVTDGRAAAGG
EEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
DLVVIDFIGKLDGEAFEGGSAEAYDLELGSNSFIPGFEDQLIGATAGEARTVTVSFPEDY
CEEEEEEHHHCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHCCCCCCCCEEEEEECCCCC
PAAHLAGKETVFDVTVKEVKQAVVPELDDDLAKAFGKESAEALREAVKADLQGELDEVSK
CCHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHH
TKLKRKLLDALADGHDFPVPQTLVDAEFEGIWAQIEKAKTDGQLDEEDAAKSDEDLRADY
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHH
RKIAERRVRLGLLLADVGQRAQVTVAQEDLNKALMRELRRFPGQEAAVINYYRNNQQAMD
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCHHHHH
NLRAPVFEDKVCAHILALATVTDKPVSVEDLMKDPDEDATPTA
HHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA