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The map label for this gene is arsA [H]

Identifier: 83592783

GI number: 83592783

Start: 1711618

End: 1713333

Strand: Reverse

Name: arsA [H]

Synonym: Rru_A1447

Alternate gene names: 83592783

Gene position: 1713333-1711618 (Counterclockwise)

Preceding gene: 83592784

Following gene: 83592779

Centisome position: 39.36

GC content: 69.81

Gene sequence:

>1716_bases
ATGGCCCTTCCCGAAACCCCCACACGCTTTATCTTTTTCACCGGCAAGGGCGGCGTTGGCAAAACCTCGCTGTCGTGCGC
CAGCGGTCTGGCTTTGGCCGAAGCCGGCAAAACGGTGCTGATCGTCAGCACCGATCCGGCCTCCAATCTGGACGAGGTCC
TGGGCACGCCCTTGGGCGACCAACCAACGGCGATCGCCGGCGCGCCCGGCCTTTACGGGCTGAACATCGACCCGGAAGCG
GCGGCCTTCGCCTATCGGGAACGCATGGTCGCCCCTTATCGGGGACTCTTGCCCGCCGCCGCCATCGCCAGCATGGAAGA
ACAGTTCTCCGGCGCCTGCACCGTCGAGATCGCCGCCTTCGACGCCTTCGCCAAGCTGCTGGGCGATGACGCGGCCACCG
CCGCATTCGATCACGTGATCTTCGATACCGCCCCCACCGGCCATACCCTGCGCCTGCTCACCCTGCCTTCGGCCTGGGGG
GATTTCATCGCCTCGGCGACCGGCGGGGCCTCCTGCCTTGGCCCTCTGGCCGGGCTGGAGACGCAAAAGGCCTTGTATGG
CGCGACGGTCGCCCATCTCGCCGATCCGAAAATGACCACGGTGGTTCTGGTCAGCCGGGCCGAAGGCGCCGCCCTGCGCG
AAGCCGAACGCACCCGGGGCGAATTGGCCGATCTGGGCGTGACCAACCAACGGCTGGCGCTGAACGGGGTGTTCACCGCG
CCCCGGGGCGAAGACGCCATCGCCGATGCCATGACCTTGCGGGGGCTCGAGGCCCTGGCGGATATGCCCGCCGCCCTGGC
CGCCCTGCCGCGCAGCCAGACCCCCTTCCTGCCGCTGGGCACCGTCGGCCTCACCGCCCTGCGCCAGATCGCCGCAGACA
CGGCGGCGGAGGCCACGCCCGCCGGCCCCGCCCCCGCCGCCGCTTTCCCGTCCCTGCCGGGCGGCCTGGAAGACCTGATC
GACGAGATCGCCGCCGCCGGCCATGGGGTGGTGATGACCATGGGCAAGGGTGGCGTGGGCAAGACCACCATCGCCGCCGC
CCTGGCCATCGCCCTGGCCCGCCGGGGCCACCGGGTCACGCTGTCGACCACCGACCCCGCCGCCCATGTCGCCCAGGCCG
TTGACGGCACGGTACCGGGGCTGACAATCGCCCGCATCGATCCCAAGGTGGAAATCGCAGGCTACCGCGCCGAGGTGCTT
GAAAAGGCGGGGAAAAACCTTGATGCCGCCGGCCGCGCCATGCTCGAGGAGGACCTGCGCTCGCCCTGTACCGAGGAAAT
CGCCGTTTTCCAGGCCTTCGCCCGCACGGTCGATGGCGGCAAGGACCACTTCGTGGTTCTGGATACGGCGCCGACCGGCC
ATACCATCTTGCTGCTCGACGCCGCCGAAGCCTATCACCGCGAGGTTCTGCGCACCCGGGCCGATATGCCCGAAGCGGTG
CGCGCCCTGCTGCCGCGCCTGCGTGACCCGGGGTTCACCAAGGCGATCATCGTCACCCTGGCCGAGGCCACCCCGGTTCA
CGAGGCAGAACGCTTACAACGCGATCTGGCGCGCGCCGGCATCACGCCTTTCGCCTGGGTGATCACCCAAAGCCTGCTCG
CCAGCGGCACCACGGATCGGCTGCTGCGCCAGCGCGGCGCCTATGAGGCGCCGTTCATCGCCCGGGTGGCGACCGAGCTG
GCCAAACGCACCGCCCTCATCCCCTGGGCCGCCTGA

Upstream 100 bases:

>100_bases
GGCCAATTGGCCGCCAAGCTGGCGCTGTCGCCAAGCCCGGCGCCGGCCGCCGCCGGGTCGTGCTGCTCGCCCCGATCGGG
CTGCTGCTAAGGAGGCCGTG

Downstream 100 bases:

>100_bases
GCGCCCCAAACTTCACGCCGGCGGCTTTAAGCGGGCCGCAGGCGGAAGGCGGTCACGGCACCGCCCCCGAAAGCGCCTTG
TCGGCGCTTCGCGGGGGCGG

Product: arsenite-transporting ATPase

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MALPETPTRFIFFTGKGGVGKTSLSCASGLALAEAGKTVLIVSTDPASNLDEVLGTPLGDQPTAIAGAPGLYGLNIDPEA
AAFAYRERMVAPYRGLLPAAAIASMEEQFSGACTVEIAAFDAFAKLLGDDAATAAFDHVIFDTAPTGHTLRLLTLPSAWG
DFIASATGGASCLGPLAGLETQKALYGATVAHLADPKMTTVVLVSRAEGAALREAERTRGELADLGVTNQRLALNGVFTA
PRGEDAIADAMTLRGLEALADMPAALAALPRSQTPFLPLGTVGLTALRQIAADTAAEATPAGPAPAAAFPSLPGGLEDLI
DEIAAAGHGVVMTMGKGGVGKTTIAAALAIALARRGHRVTLSTTDPAAHVAQAVDGTVPGLTIARIDPKVEIAGYRAEVL
EKAGKNLDAAGRAMLEEDLRSPCTEEIAVFQAFARTVDGGKDHFVVLDTAPTGHTILLLDAAEAYHREVLRTRADMPEAV
RALLPRLRDPGFTKAIIVTLAEATPVHEAERLQRDLARAGITPFAWVITQSLLASGTTDRLLRQRGAYEAPFIARVATEL
AKRTALIPWAA

Sequences:

>Translated_571_residues
MALPETPTRFIFFTGKGGVGKTSLSCASGLALAEAGKTVLIVSTDPASNLDEVLGTPLGDQPTAIAGAPGLYGLNIDPEA
AAFAYRERMVAPYRGLLPAAAIASMEEQFSGACTVEIAAFDAFAKLLGDDAATAAFDHVIFDTAPTGHTLRLLTLPSAWG
DFIASATGGASCLGPLAGLETQKALYGATVAHLADPKMTTVVLVSRAEGAALREAERTRGELADLGVTNQRLALNGVFTA
PRGEDAIADAMTLRGLEALADMPAALAALPRSQTPFLPLGTVGLTALRQIAADTAAEATPAGPAPAAAFPSLPGGLEDLI
DEIAAAGHGVVMTMGKGGVGKTTIAAALAIALARRGHRVTLSTTDPAAHVAQAVDGTVPGLTIARIDPKVEIAGYRAEVL
EKAGKNLDAAGRAMLEEDLRSPCTEEIAVFQAFARTVDGGKDHFVVLDTAPTGHTILLLDAAEAYHREVLRTRADMPEAV
RALLPRLRDPGFTKAIIVTLAEATPVHEAERLQRDLARAGITPFAWVITQSLLASGTTDRLLRQRGAYEAPFIARVATEL
AKRTALIPWAA
>Mature_570_residues
ALPETPTRFIFFTGKGGVGKTSLSCASGLALAEAGKTVLIVSTDPASNLDEVLGTPLGDQPTAIAGAPGLYGLNIDPEAA
AFAYRERMVAPYRGLLPAAAIASMEEQFSGACTVEIAAFDAFAKLLGDDAATAAFDHVIFDTAPTGHTLRLLTLPSAWGD
FIASATGGASCLGPLAGLETQKALYGATVAHLADPKMTTVVLVSRAEGAALREAERTRGELADLGVTNQRLALNGVFTAP
RGEDAIADAMTLRGLEALADMPAALAALPRSQTPFLPLGTVGLTALRQIAADTAAEATPAGPAPAAAFPSLPGGLEDLID
EIAAAGHGVVMTMGKGGVGKTTIAAALAIALARRGHRVTLSTTDPAAHVAQAVDGTVPGLTIARIDPKVEIAGYRAEVLE
KAGKNLDAAGRAMLEEDLRSPCTEEIAVFQAFARTVDGGKDHFVVLDTAPTGHTILLLDAAEAYHREVLRTRADMPEAVR
ALLPRLRDPGFTKAIIVTLAEATPVHEAERLQRDLARAGITPFAWVITQSLLASGTTDRLLRQRGAYEAPFIARVATELA
KRTALIPWAA

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=299, Percent_Identity=27.4247491638796, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17557003, Length=266, Percent_Identity=28.9473684210526, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320103, Length=251, Percent_Identity=28.2868525896414, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24586297, Length=308, Percent_Identity=24.3506493506494, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016300
- InterPro:   IPR003593
- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 59170; Mature: 59039

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPETPTRFIFFTGKGGVGKTSLSCASGLALAEAGKTVLIVSTDPASNLDEVLGTPLGD
CCCCCCCCEEEEEECCCCCCCCHHHHHHCCHHHHCCCEEEEEECCCCCCHHHHHCCCCCC
QPTAIAGAPGLYGLNIDPEAAAFAYRERMVAPYRGLLPAAAIASMEEQFSGACTVEIAAF
CCCEEECCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEHHH
DAFAKLLGDDAATAAFDHVIFDTAPTGHTLRLLTLPSAWGDFIASATGGASCLGPLAGLE
HHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHCCCCHHHHHHHHCCC
TQKALYGATVAHLADPKMTTVVLVSRAEGAALREAERTRGELADLGVTNQRLALNGVFTA
HHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEC
PRGEDAIADAMTLRGLEALADMPAALAALPRSQTPFLPLGTVGLTALRQIAADTAAEATP
CCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
AGPAPAAAFPSLPGGLEDLIDEIAAAGHGVVMTMGKGGVGKTTIAAALAIALARRGHRVT
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEE
LSTTDPAAHVAQAVDGTVPGLTIARIDPKVEIAGYRAEVLEKAGKNLDAAGRAMLEEDLR
EECCCHHHHHHHHHCCCCCCEEEEEECCCEEECCHHHHHHHHHCCCCCHHHHHHHHHHHH
SPCTEEIAVFQAFARTVDGGKDHFVVLDTAPTGHTILLLDAAEAYHREVLRTRADMPEAV
CCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEECHHHHHHHHHHHHCCCHHHH
RALLPRLRDPGFTKAIIVTLAEATPVHEAERLQRDLARAGITPFAWVITQSLLASGTTDR
HHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHH
LLRQRGAYEAPFIARVATELAKRTALIPWAA
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ALPETPTRFIFFTGKGGVGKTSLSCASGLALAEAGKTVLIVSTDPASNLDEVLGTPLGD
CCCCCCCEEEEEECCCCCCCCHHHHHHCCHHHHCCCEEEEEECCCCCCHHHHHCCCCCC
QPTAIAGAPGLYGLNIDPEAAAFAYRERMVAPYRGLLPAAAIASMEEQFSGACTVEIAAF
CCCEEECCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEHHH
DAFAKLLGDDAATAAFDHVIFDTAPTGHTLRLLTLPSAWGDFIASATGGASCLGPLAGLE
HHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHCCCCHHHHHHHHCCC
TQKALYGATVAHLADPKMTTVVLVSRAEGAALREAERTRGELADLGVTNQRLALNGVFTA
HHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEC
PRGEDAIADAMTLRGLEALADMPAALAALPRSQTPFLPLGTVGLTALRQIAADTAAEATP
CCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
AGPAPAAAFPSLPGGLEDLIDEIAAAGHGVVMTMGKGGVGKTTIAAALAIALARRGHRVT
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEE
LSTTDPAAHVAQAVDGTVPGLTIARIDPKVEIAGYRAEVLEKAGKNLDAAGRAMLEEDLR
EECCCHHHHHHHHHCCCCCCEEEEEECCCEEECCHHHHHHHHHCCCCCHHHHHHHHHHHH
SPCTEEIAVFQAFARTVDGGKDHFVVLDTAPTGHTILLLDAAEAYHREVLRTRADMPEAV
CCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEECHHHHHHHHHHHHCCCHHHH
RALLPRLRDPGFTKAIIVTLAEATPVHEAERLQRDLARAGITPFAWVITQSLLASGTTDR
HHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHH
LLRQRGAYEAPFIARVATELAKRTALIPWAA
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3021763; 1704144 [H]