Click here to switch to the map view.

The map label for this gene is atoS [H]

Identifier: 83592720

GI number: 83592720

Start: 1632653

End: 1634506

Strand: Direct

Name: atoS [H]

Synonym: Rru_A1384

Alternate gene names: 83592720

Gene position: 1632653-1634506 (Clockwise)

Preceding gene: 83592690

Following gene: 83592721

Centisome position: 37.51

GC content: 62.84

Gene sequence:

>1854_bases
GTGCGCCTCAGCGACCTCTCGCGTATCCTGCCTTTGCGGAGTCTGCGCCATCGGTTGATGCTGACCTCGCTGATCGTCGT
CGCCTTGCCGATCGCCATCGTTGGCATCGTCTTCGAACACGAGGGGCGGCAGGCGCTGCTTCATGAAAAGCAAAGCAAGC
TGTTCGGCCTGACCCAAATTCTCGATGCCGAGCTTGGCCCTGGCTTTGACTCCCTGCTCGCCGATCTGCCCAGCGGCTGG
ACCGACCGCGCCGCGGCCATCGCCCATCTCAGCGCCAAGTTGACGCTTCAGACCGATCGCATCGCCGGGATCGGCGACGG
CATCGCCGTCGGCTATTATTCCAAGCGTCTGGACGCCATCATCACCTATGGGCCAAGCGCCTCCTACGCCAAGACCATCG
GCGTTTCGATCACCGCCGACCATCCGGGGCGCGCCGTGATGGACAGCGCCAAGCCACGGGTCGAATTCGGCACGCTGGTG
CGCGGTCAGATCATGAACGCCATGCTGCCGATCATCCGCAACGACGAGGTGATCGGCTATATCTGGGCCAATGAGTTCAT
CGAGGCGATCGAGAACCAGCAGAACGTCTTTCATCGCGCCGTGCTGTTCGTCAGCCTCGCCGGGATCGGCATCGCCTTCT
TTGTCGTCAATTCGATGTCGCGCCGGCTGTCGCAGGAGGTCGGCGTCATCGTCGATGGCCTCGCCGTCATGGAAAACGAT
CTGCGCCGGCCGCTGCCGCCGTTGCGCGACGAGTTGGGCAATATCGTCGATGCCATCAACGCCATGGCCAAGGCATTGCT
CGATGCGCGGTCGCTGACGGAAAACATCCTGGCCAGCGTCGCCGACGGTATCGTCGCCGTCGATCTCAAGGGTACTATCA
CCGCCTTCAATCCGGCCGCCGAGCAGATGTATTCGATGTCGGCCGACGCGGTGATCGGCAAGCCCTATCACGCGCTGTTC
ATCAGCGGCACCGATATGGTCAGCGTGCTGCTCGATACCCTGGAAACCGGCTGCACCCATATCGGCGTGACCCCGGACCT
GCCCAATCTGGACGGCACCTTGAAGATCTCGGCGTCTTCCAGCGTGCTGCGCGACGGCGAGGGGCAGCCCATCGGCGCGG
TGGTGGTGCTCAAGGATGTCAGTGAACGCGACCGGCTGATGGTGCAGGTGATGCGGGCCGATCGGCTGGCCGCCCTGGGC
GAACTAACCGCCGGCATCGCCCATGAGATCAGAAACCCGCTGACCTCGATCCGTGGCTTCGTCCAGTATCTGATGGAATG
CGCGAGCCCCAAGGAATGGCAGCATTACGGGCCGCTGATCATCCGTCAGGTCGACAGCCTCAACCATATCATCACCGAAC
TGCTGGCCTTCGGCCGGCCGCGCGCGCCGCGTATCGACAAGGTTCACCTGGATCAGATCGCCCAGGAAATGGCCTTTCTG
GCGCGGGGGAAATCCGAAGCGCGCATCGAAATGGACCTGGAGGGCGAGGTGCCGGCGATCGAGGCCGATGGCGAATCGCT
CAAGCAGGCGCTGCTCAATCTGATCATCAACGCCATGCAGGCGATTTCCAAGGATGGGTCGGTCACCGTGGCGGTGCGCC
GCCTGGGCGATGACCATGTGATGGTCAAGGTCAGCGATGACGGCATCGGTCTGGCCCCCGACTATCTCGACAAGGTTTTC
GACCCGTTCTTTTCAACCAAGCCGGCCGGGACGGGTCTGGGGCTGGCGGTCGTTCATCGCATCGTCGATGCCCATCAGGG
CGTCATCACCCTTGATAGCCGCCTTGGCGAGGGAACGGTGGTGACCATCCGCCTGCCCGTGGTTCGTTCGAAGCAGGAGA
GTCCCCCATGTTAG

Upstream 100 bases:

>100_bases
TCACTGCTCTTATCTATGACTCTTCTATGCCGTTGGCGGTTTTGAAGGGGCGCTCGGCGGAAAATTCAATCCATGATTTT
ACCCCATCGAGGGATCCCCC

Downstream 100 bases:

>100_bases
CCCCCGCCCAGACCGTTCTGATCGTCGATGACGACGAGGCCATCCGCCAGATGCTGTCGGCCTTCTTGTCCAAGGAAGGC
CTGAGGGTGGTGACGGCGCG

Product: sensory histidine kinase AtoS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 617; Mature: 617

Protein sequence:

>617_residues
MRLSDLSRILPLRSLRHRLMLTSLIVVALPIAIVGIVFEHEGRQALLHEKQSKLFGLTQILDAELGPGFDSLLADLPSGW
TDRAAAIAHLSAKLTLQTDRIAGIGDGIAVGYYSKRLDAIITYGPSASYAKTIGVSITADHPGRAVMDSAKPRVEFGTLV
RGQIMNAMLPIIRNDEVIGYIWANEFIEAIENQQNVFHRAVLFVSLAGIGIAFFVVNSMSRRLSQEVGVIVDGLAVMEND
LRRPLPPLRDELGNIVDAINAMAKALLDARSLTENILASVADGIVAVDLKGTITAFNPAAEQMYSMSADAVIGKPYHALF
ISGTDMVSVLLDTLETGCTHIGVTPDLPNLDGTLKISASSSVLRDGEGQPIGAVVVLKDVSERDRLMVQVMRADRLAALG
ELTAGIAHEIRNPLTSIRGFVQYLMECASPKEWQHYGPLIIRQVDSLNHIITELLAFGRPRAPRIDKVHLDQIAQEMAFL
ARGKSEARIEMDLEGEVPAIEADGESLKQALLNLIINAMQAISKDGSVTVAVRRLGDDHVMVKVSDDGIGLAPDYLDKVF
DPFFSTKPAGTGLGLAVVHRIVDAHQGVITLDSRLGEGTVVTIRLPVVRSKQESPPC

Sequences:

>Translated_617_residues
MRLSDLSRILPLRSLRHRLMLTSLIVVALPIAIVGIVFEHEGRQALLHEKQSKLFGLTQILDAELGPGFDSLLADLPSGW
TDRAAAIAHLSAKLTLQTDRIAGIGDGIAVGYYSKRLDAIITYGPSASYAKTIGVSITADHPGRAVMDSAKPRVEFGTLV
RGQIMNAMLPIIRNDEVIGYIWANEFIEAIENQQNVFHRAVLFVSLAGIGIAFFVVNSMSRRLSQEVGVIVDGLAVMEND
LRRPLPPLRDELGNIVDAINAMAKALLDARSLTENILASVADGIVAVDLKGTITAFNPAAEQMYSMSADAVIGKPYHALF
ISGTDMVSVLLDTLETGCTHIGVTPDLPNLDGTLKISASSSVLRDGEGQPIGAVVVLKDVSERDRLMVQVMRADRLAALG
ELTAGIAHEIRNPLTSIRGFVQYLMECASPKEWQHYGPLIIRQVDSLNHIITELLAFGRPRAPRIDKVHLDQIAQEMAFL
ARGKSEARIEMDLEGEVPAIEADGESLKQALLNLIINAMQAISKDGSVTVAVRRLGDDHVMVKVSDDGIGLAPDYLDKVF
DPFFSTKPAGTGLGLAVVHRIVDAHQGVITLDSRLGEGTVVTIRLPVVRSKQESPPC
>Mature_617_residues
MRLSDLSRILPLRSLRHRLMLTSLIVVALPIAIVGIVFEHEGRQALLHEKQSKLFGLTQILDAELGPGFDSLLADLPSGW
TDRAAAIAHLSAKLTLQTDRIAGIGDGIAVGYYSKRLDAIITYGPSASYAKTIGVSITADHPGRAVMDSAKPRVEFGTLV
RGQIMNAMLPIIRNDEVIGYIWANEFIEAIENQQNVFHRAVLFVSLAGIGIAFFVVNSMSRRLSQEVGVIVDGLAVMEND
LRRPLPPLRDELGNIVDAINAMAKALLDARSLTENILASVADGIVAVDLKGTITAFNPAAEQMYSMSADAVIGKPYHALF
ISGTDMVSVLLDTLETGCTHIGVTPDLPNLDGTLKISASSSVLRDGEGQPIGAVVVLKDVSERDRLMVQVMRADRLAALG
ELTAGIAHEIRNPLTSIRGFVQYLMECASPKEWQHYGPLIIRQVDSLNHIITELLAFGRPRAPRIDKVHLDQIAQEMAFL
ARGKSEARIEMDLEGEVPAIEADGESLKQALLNLIINAMQAISKDGSVTVAVRRLGDDHVMVKVSDDGIGLAPDYLDKVF
DPFFSTKPAGTGLGLAVVHRIVDAHQGVITLDSRLGEGTVVTIRLPVVRSKQESPPC

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=598, Percent_Identity=40.8026755852843, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=39.3013100436681, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1790300, Length=347, Percent_Identity=27.0893371757925, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI48994928, Length=244, Percent_Identity=31.5573770491803, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=28.2945736434109, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790567, Length=338, Percent_Identity=27.810650887574, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1789808, Length=211, Percent_Identity=29.3838862559242, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786783, Length=226, Percent_Identity=27.8761061946903, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787894, Length=279, Percent_Identity=26.5232974910394, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790861, Length=215, Percent_Identity=29.3023255813954, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786600, Length=251, Percent_Identity=24.7011952191235, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788713, Length=235, Percent_Identity=26.8085106382979, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87081816, Length=220, Percent_Identity=27.7272727272727, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=28.2511210762332, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=27.6150627615063, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1789149, Length=221, Percent_Identity=25.7918552036199, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66697; Mature: 66697

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSDLSRILPLRSLRHRLMLTSLIVVALPIAIVGIVFEHEGRQALLHEKQSKLFGLTQI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LDAELGPGFDSLLADLPSGWTDRAAAIAHLSAKLTLQTDRIAGIGDGIAVGYYSKRLDAI
HHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHEEEEEEECCCCCCCCCEEEHHHHHCCCEE
ITYGPSASYAKTIGVSITADHPGRAVMDSAKPRVEFGTLVRGQIMNAMLPIIRNDEVIGY
EEECCCCCCHHHEEEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
IWANEFIEAIENQQNVFHRAVLFVSLAGIGIAFFVVNSMSRRLSQEVGVIVDGLAVMEND
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRPLPPLRDELGNIVDAINAMAKALLDARSLTENILASVADGIVAVDLKGTITAFNPAA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCHHH
EQMYSMSADAVIGKPYHALFISGTDMVSVLLDTLETGCTHIGVTPDLPNLDGTLKISASS
HHHHHCCCCCEECCCEEEEEEECHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEEEECCC
SVLRDGEGQPIGAVVVLKDVSERDRLMVQVMRADRLAALGELTAGIAHEIRNPLTSIRGF
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQYLMECASPKEWQHYGPLIIRQVDSLNHIITELLAFGRPRAPRIDKVHLDQIAQEMAFL
HHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
ARGKSEARIEMDLEGEVPAIEADGESLKQALLNLIINAMQAISKDGSVTVAVRRLGDDHV
HCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEE
MVKVSDDGIGLAPDYLDKVFDPFFSTKPAGTGLGLAVVHRIVDAHQGVITLDSRLGEGTV
EEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEE
VTIRLPVVRSKQESPPC
EEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRLSDLSRILPLRSLRHRLMLTSLIVVALPIAIVGIVFEHEGRQALLHEKQSKLFGLTQI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LDAELGPGFDSLLADLPSGWTDRAAAIAHLSAKLTLQTDRIAGIGDGIAVGYYSKRLDAI
HHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHEEEEEEECCCCCCCCCEEEHHHHHCCCEE
ITYGPSASYAKTIGVSITADHPGRAVMDSAKPRVEFGTLVRGQIMNAMLPIIRNDEVIGY
EEECCCCCCHHHEEEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
IWANEFIEAIENQQNVFHRAVLFVSLAGIGIAFFVVNSMSRRLSQEVGVIVDGLAVMEND
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRPLPPLRDELGNIVDAINAMAKALLDARSLTENILASVADGIVAVDLKGTITAFNPAA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCHHH
EQMYSMSADAVIGKPYHALFISGTDMVSVLLDTLETGCTHIGVTPDLPNLDGTLKISASS
HHHHHCCCCCEECCCEEEEEEECHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEEEECCC
SVLRDGEGQPIGAVVVLKDVSERDRLMVQVMRADRLAALGELTAGIAHEIRNPLTSIRGF
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQYLMECASPKEWQHYGPLIIRQVDSLNHIITELLAFGRPRAPRIDKVHLDQIAQEMAFL
HHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
ARGKSEARIEMDLEGEVPAIEADGESLKQALLNLIINAMQAISKDGSVTVAVRRLGDDHV
HCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEE
MVKVSDDGIGLAPDYLDKVFDPFFSTKPAGTGLGLAVVHRIVDAHQGVITLDSRLGEGTV
EEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEE
VTIRLPVVRSKQESPPC
EEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]