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The map label for this gene is sucD [H]

Identifier: 83592548

GI number: 83592548

Start: 1430159

End: 1431037

Strand: Direct

Name: sucD [H]

Synonym: Rru_A1212

Alternate gene names: 83592548

Gene position: 1430159-1431037 (Clockwise)

Preceding gene: 83592547

Following gene: 161777626

Centisome position: 32.86

GC content: 65.42

Gene sequence:

>879_bases
ATGTCTGTTCTCGTCAGCAACGACACCAAGGTCATCTGCCAGGGCTTCACCGGCTCCCAGGGGACTTTCCACTCCGAGCA
GGCCATCGCCTATGGCACCAAGATGGTCGGCGGCGTGACTCCGGGCAAGGGCGGCTCGACCCACCTTGATCTGCCGGTTT
TCGACACGGTGATCCAGGCGCGCGAGGCCACCGGCTGCAACGCCACGGTCATCTATGTGCCGCCGCCCTTCGCCGCCGAC
GCCATCCTCGAGGCGATCAACGCCGAGATCGAACTGGCCGTCTGCATCACCGAGGGCATTCCGGTGCTTGACATGGTCAA
GGTCAAGCGGGCGCTGCGCGGTTCGAAGACCCGGCTGATCGGCCCGAACTGCCCCGGCGTCATCACCCCGGGCGAATGCA
AGATCGGCATCATGCCCGGTCATATCCATACCCGGGGCAAGATCGGCGTGGTGTCGCGCTCGGGGACGCTGACCTATGAG
GCGGTGGCCCAGACCACGGCGGCCGGTCTTGGTCAGTCGACCTGCATCGGCATTGGGGGCGATCCGGTCAACGGCACCAA
CTTCATCGACTGCCTGGAGATGTTCCTGGCCGATCCCGAGACCCAGGGCATCATCATGATCGGCGAGATCGGCGGGTCGG
CCGAAGAGGAAGCCGCCGAGTTCCTCAAGCACTCCAAGATCAAAAAGCCGATGTGCGGCTTCATCGCCGGGGTCACCGCC
CCGCCGGGCAAGCGCATGGGCCACGCCGGCGCCATCATCTCGGGCGGCAAGGGAACCGCCGGGGATAAAATGGACGCCAT
GCGATCGGCTGGAATCCTGGTCGCCGACAGCCCGTCGGCGCTGGGAAGCACCATGGTCGAGGCGATGAAGTCCGCCTGA

Upstream 100 bases:

>100_bases
GCAAGAAGATCATGGTCGAGTCCGGCCTGCCGATCATTTCGGCGGATAATTTGGCCGACGCCGCCGAAAAGGTGGTCAAG
GCGGTGAAGGAGGCTTCCTG

Downstream 100 bases:

>100_bases
CGCGTAATGCGAGCCCCCCCAGGAAAACCTTTCCCGGGGGGGTTCCTGTTTGGGGGCGGGGCGCCTACCTACTACGAGCG
AAGAGCCGACCGTTGTCGGA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSVLVSNDTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKGGSTHLDLPVFDTVIQAREATGCNATVIYVPPPFAAD
AILEAINAEIELAVCITEGIPVLDMVKVKRALRGSKTRLIGPNCPGVITPGECKIGIMPGHIHTRGKIGVVSRSGTLTYE
AVAQTTAAGLGQSTCIGIGGDPVNGTNFIDCLEMFLADPETQGIIMIGEIGGSAEEEAAEFLKHSKIKKPMCGFIAGVTA
PPGKRMGHAGAIISGGKGTAGDKMDAMRSAGILVADSPSALGSTMVEAMKSA

Sequences:

>Translated_292_residues
MSVLVSNDTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKGGSTHLDLPVFDTVIQAREATGCNATVIYVPPPFAAD
AILEAINAEIELAVCITEGIPVLDMVKVKRALRGSKTRLIGPNCPGVITPGECKIGIMPGHIHTRGKIGVVSRSGTLTYE
AVAQTTAAGLGQSTCIGIGGDPVNGTNFIDCLEMFLADPETQGIIMIGEIGGSAEEEAAEFLKHSKIKKPMCGFIAGVTA
PPGKRMGHAGAIISGGKGTAGDKMDAMRSAGILVADSPSALGSTMVEAMKSA
>Mature_291_residues
SVLVSNDTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKGGSTHLDLPVFDTVIQAREATGCNATVIYVPPPFAADA
ILEAINAEIELAVCITEGIPVLDMVKVKRALRGSKTRLIGPNCPGVITPGECKIGIMPGHIHTRGKIGVVSRSGTLTYEA
VAQTTAAGLGQSTCIGIGGDPVNGTNFIDCLEMFLADPETQGIIMIGEIGGSAEEEAAEFLKHSKIKKPMCGFIAGVTAP
PGKRMGHAGAIISGGKGTAGDKMDAMRSAGILVADSPSALGSTMVEAMKSA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=292, Percent_Identity=69.5205479452055, Blast_Score=353, Evalue=1e-97,
Organism=Homo sapiens, GI38569423, Length=254, Percent_Identity=28.3464566929134, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI38569421, Length=254, Percent_Identity=28.3464566929134, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1786949, Length=290, Percent_Identity=68.2758620689655, Blast_Score=400, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17550194, Length=292, Percent_Identity=65.7534246575342, Blast_Score=372, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=65.7534246575342, Blast_Score=370, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17557344, Length=316, Percent_Identity=29.4303797468354, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17551266, Length=258, Percent_Identity=28.2945736434109, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324716, Length=296, Percent_Identity=53.7162162162162, Blast_Score=297, Evalue=1e-81,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=60.6164383561644, Blast_Score=358, Evalue=2e-99,
Organism=Drosophila melanogaster, GI28574296, Length=293, Percent_Identity=67.2354948805461, Blast_Score=357, Evalue=5e-99,
Organism=Drosophila melanogaster, GI281363477, Length=222, Percent_Identity=31.981981981982, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281363475, Length=222, Percent_Identity=31.981981981982, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281363473, Length=222, Percent_Identity=31.981981981982, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29858; Mature: 29727

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVSNDTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKGGSTHLDLPVFDTVIQA
CEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHH
REATGCNATVIYVPPPFAADAILEAINAEIELAVCITEGIPVLDMVKVKRALRGSKTRLI
HCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEE
GPNCPGVITPGECKIGIMPGHIHTRGKIGVVSRSGTLTYEAVAQTTAAGLGQSTCIGIGG
CCCCCCEECCCCEEEEEECCCEECCCEEEEEECCCCEEHHHHHHHHHHCCCCCEEEECCC
DPVNGTNFIDCLEMFLADPETQGIIMIGEIGGSAEEEAAEFLKHSKIKKPMCGFIAGVTA
CCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCC
PPGKRMGHAGAIISGGKGTAGDKMDAMRSAGILVADSPSALGSTMVEAMKSA
CCCCCCCCCCEEEECCCCCCCCHHHHHHHCCEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVLVSNDTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKGGSTHLDLPVFDTVIQA
EEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHH
REATGCNATVIYVPPPFAADAILEAINAEIELAVCITEGIPVLDMVKVKRALRGSKTRLI
HCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEE
GPNCPGVITPGECKIGIMPGHIHTRGKIGVVSRSGTLTYEAVAQTTAAGLGQSTCIGIGG
CCCCCCEECCCCEEEEEECCCEECCCEEEEEECCCCEEHHHHHHHHHHCCCCCEEEECCC
DPVNGTNFIDCLEMFLADPETQGIIMIGEIGGSAEEEAAEFLKHSKIKKPMCGFIAGVTA
CCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCC
PPGKRMGHAGAIISGGKGTAGDKMDAMRSAGILVADSPSALGSTMVEAMKSA
CCCCCCCCCCEEEECCCCCCCCHHHHHHHCCEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]