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The map label for this gene is yleA [C]

Identifier: 83592518

GI number: 83592518

Start: 1399551

End: 1400876

Strand: Reverse

Name: yleA [C]

Synonym: Rru_A1182

Alternate gene names: 83592518

Gene position: 1400876-1399551 (Counterclockwise)

Preceding gene: 83592519

Following gene: 83592517

Centisome position: 32.18

GC content: 69.53

Gene sequence:

>1326_bases
ATGACCGCCACTCCCCTCGCGCCGCCGACGGCCGATGCGATCGACGATAACGCCAGCCCCGGCGGTCCGCGCATCGTCAC
TTTCGGCTGCCGTCTCAATACCTATGAATCCGAGGTGATGCGCGAACAGGCGGCCAAGGCCGGGCTGAGCGATGCCATCA
TCGTCAATACCTGCGCCGTCACCCGCGAGGCCGAGCGTCAGGCCCGCCAGACCATCCGCCGCCTGCGCCGCGAGAATCCG
GAAACCCGGCTGATCGTCACCGGCTGCGGCGCCCAGCTTGACCCGAAAGGCTGGGGGGCGATGCCCGAGGTCGATCAGGT
GCTGGGCAACGAGGAAAAGCTGAAGGCGGAAAGCTATCGGCCGCTGGCCGGCGGACTTGACCTGGGCGCCCCGGAAAAGA
TCCTGGTCGACGACATCATGACCGTGCGCGAAACCGCGCTGCATCTGGTCGGCGGCTTCGAGGGACGGGCCCGCGCCTTC
GTTCAGGTTCAGCAGGGCTGCGACCACCGCTGCACCTTCTGCATCATCCCCTTCGCCCGCGGCAACAGCCGCAGCGTGCC
GATGGGCCGCATCGTCGACCAGATCCGCGCCCTGGTCGCGGCCGGCTATCGGGAAGTGGTGCTAACCGGGGTCGACATCA
CCGCCTATGGTCCCGATCTGCCCGGGGCGCCAAGCCTGGGTCAGATGGTGCGCCGCCTGCTGCGCGCCGTGCCGGACCTG
CCCCGCCTGCGGCTGTCGAGCCTTGATCCGGTCGAGGTCGACGAGGATCTGCTGGCCCTGGTGGCCAGCGAGCCCCGGCT
GCTCGCCCATCTTCATCTCTCGGTTCAGGCCGGCGCCGATCTGATCCTCAAGCGCATGAAGCGCCGCCACCTGCGCGACG
ACGTCATCGCCCTCGCCCAGCGCCTGCGGACGCTGCGCCCCGGGATGGCGCTGGGCGCCGATATCATCGTCGGCTTCCCC
ACCGAAACCGAAGAGCACTTCGCCCAATCCCTGGCCCTGGTCGAGGAGGCCGGGCTGACCCATCTGCATGTGTTCCCCTA
TAGCCCGCGCCCGGGAACCCCGGCGGCGCTGATGCCCCAGGTCGACAAGGCCGTGGTCAAGGACCGGGCGCGGCGCCTGC
GCGAGGCCGGCGAAGCGGCCCTGGCCGCCCACCGCGCCGTGCTGGTCGGCGGCATCGACCATGTTTTGATCGAACGCCCT
GGCGAAGGCCATGGCGAGACCTTTGTCCCCGTGAGCGTGGACCCGGCCCTGACGCCGGGCAGCATCGTGCCCGTCCGGCT
GCGCGCCGGTGAGGGTGGCCATCTGATCGGAGAAGCCGTTTCGTGA

Upstream 100 bases:

>100_bases
GCACGCTTGGCATCGTCTGGCGCGAAAGCGACGGCCATGTGCTGATGACCGGCAGTGCCACCCTGGCCTATTCGGGGGTC
CTGGACGAAGGAGCCTGGGC

Downstream 100 bases:

>100_bases
GCGAGCACAGCGCCAATCAGCGGAAGAAGAAGGGCACCGCCGTGGCGGTCCCGACGTCCCTCGAAAGCCGGCCCCGCCGT
CGCATCGACCCGCTCGCCCA

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MTATPLAPPTADAIDDNASPGGPRIVTFGCRLNTYESEVMREQAAKAGLSDAIIVNTCAVTREAERQARQTIRRLRRENP
ETRLIVTGCGAQLDPKGWGAMPEVDQVLGNEEKLKAESYRPLAGGLDLGAPEKILVDDIMTVRETALHLVGGFEGRARAF
VQVQQGCDHRCTFCIIPFARGNSRSVPMGRIVDQIRALVAAGYREVVLTGVDITAYGPDLPGAPSLGQMVRRLLRAVPDL
PRLRLSSLDPVEVDEDLLALVASEPRLLAHLHLSVQAGADLILKRMKRRHLRDDVIALAQRLRTLRPGMALGADIIVGFP
TETEEHFAQSLALVEEAGLTHLHVFPYSPRPGTPAALMPQVDKAVVKDRARRLREAGEAALAAHRAVLVGGIDHVLIERP
GEGHGETFVPVSVDPALTPGSIVPVRLRAGEGGHLIGEAVS

Sequences:

>Translated_441_residues
MTATPLAPPTADAIDDNASPGGPRIVTFGCRLNTYESEVMREQAAKAGLSDAIIVNTCAVTREAERQARQTIRRLRRENP
ETRLIVTGCGAQLDPKGWGAMPEVDQVLGNEEKLKAESYRPLAGGLDLGAPEKILVDDIMTVRETALHLVGGFEGRARAF
VQVQQGCDHRCTFCIIPFARGNSRSVPMGRIVDQIRALVAAGYREVVLTGVDITAYGPDLPGAPSLGQMVRRLLRAVPDL
PRLRLSSLDPVEVDEDLLALVASEPRLLAHLHLSVQAGADLILKRMKRRHLRDDVIALAQRLRTLRPGMALGADIIVGFP
TETEEHFAQSLALVEEAGLTHLHVFPYSPRPGTPAALMPQVDKAVVKDRARRLREAGEAALAAHRAVLVGGIDHVLIERP
GEGHGETFVPVSVDPALTPGSIVPVRLRAGEGGHLIGEAVS
>Mature_440_residues
TATPLAPPTADAIDDNASPGGPRIVTFGCRLNTYESEVMREQAAKAGLSDAIIVNTCAVTREAERQARQTIRRLRRENPE
TRLIVTGCGAQLDPKGWGAMPEVDQVLGNEEKLKAESYRPLAGGLDLGAPEKILVDDIMTVRETALHLVGGFEGRARAFV
QVQQGCDHRCTFCIIPFARGNSRSVPMGRIVDQIRALVAAGYREVVLTGVDITAYGPDLPGAPSLGQMVRRLLRAVPDLP
RLRLSSLDPVEVDEDLLALVASEPRLLAHLHLSVQAGADLILKRMKRRHLRDDVIALAQRLRTLRPGMALGADIIVGFPT
ETEEHFAQSLALVEEAGLTHLHVFPYSPRPGTPAALMPQVDKAVVKDRARRLREAGEAALAAHRAVLVGGIDHVLIERPG
EGHGETFVPVSVDPALTPGSIVPVRLRAGEGGHLIGEAVS

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=387, Percent_Identity=31.266149870801, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI28872782, Length=424, Percent_Identity=24.5283018867925, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI28872784, Length=420, Percent_Identity=24.7619047619048, Blast_Score=132, Evalue=6e-31,
Organism=Escherichia coli, GI1786882, Length=408, Percent_Identity=29.1666666666667, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787057, Length=367, Percent_Identity=29.9727520435967, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17553146, Length=382, Percent_Identity=28.5340314136126, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71996771, Length=291, Percent_Identity=28.5223367697594, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI21356207, Length=436, Percent_Identity=28.6697247706422, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI19922432, Length=460, Percent_Identity=29.7826086956522, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47495; Mature: 47364

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATPLAPPTADAIDDNASPGGPRIVTFGCRLNTYESEVMREQAAKAGLSDAIIVNTCAV
CCCCCCCCCCCHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEHHHH
TREAERQARQTIRRLRRENPETRLIVTGCGAQLDPKGWGAMPEVDQVLGNEEKLKAESYR
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEECCCCCCCCCHHHHHHCCHHHHHHHCCC
PLAGGLDLGAPEKILVDDIMTVRETALHLVGGFEGRARAFVQVQQGCDHRCTFCIIPFAR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEEECC
GNSRSVPMGRIVDQIRALVAAGYREVVLTGVDITAYGPDLPGAPSLGQMVRRLLRAVPDL
CCCCCCCHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCCCHHHHHHHHHHHCCCC
PRLRLSSLDPVEVDEDLLALVASEPRLLAHLHLSVQAGADLILKRMKRRHLRDDVIALAQ
CCHHCCCCCCCCCCHHHHHHHHCCCCEEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHH
RLRTLRPGMALGADIIVGFPTETEEHFAQSLALVEEAGLTHLHVFPYSPRPGTPAALMPQ
HHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHH
VDKAVVKDRARRLREAGEAALAAHRAVLVGGIDHVLIERPGEGHGETFVPVSVDPALTPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCEEEEEECCCCCCCC
SIVPVRLRAGEGGHLIGEAVS
CEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TATPLAPPTADAIDDNASPGGPRIVTFGCRLNTYESEVMREQAAKAGLSDAIIVNTCAV
CCCCCCCCCCHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEHHHH
TREAERQARQTIRRLRRENPETRLIVTGCGAQLDPKGWGAMPEVDQVLGNEEKLKAESYR
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEECCCCCCCCCHHHHHHCCHHHHHHHCCC
PLAGGLDLGAPEKILVDDIMTVRETALHLVGGFEGRARAFVQVQQGCDHRCTFCIIPFAR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEEECC
GNSRSVPMGRIVDQIRALVAAGYREVVLTGVDITAYGPDLPGAPSLGQMVRRLLRAVPDL
CCCCCCCHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCCCHHHHHHHHHHHCCCC
PRLRLSSLDPVEVDEDLLALVASEPRLLAHLHLSVQAGADLILKRMKRRHLRDDVIALAQ
CCHHCCCCCCCCCCHHHHHHHHCCCCEEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHH
RLRTLRPGMALGADIIVGFPTETEEHFAQSLALVEEAGLTHLHVFPYSPRPGTPAALMPQ
HHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHH
VDKAVVKDRARRLREAGEAALAAHRAVLVGGIDHVLIERPGEGHGETFVPVSVDPALTPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCEEEEEECCCCCCCC
SIVPVRLRAGEGGHLIGEAVS
CEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]