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The map label for this gene is argD [H]

Identifier: 83592483

GI number: 83592483

Start: 1354127

End: 1355311

Strand: Direct

Name: argD [H]

Synonym: Rru_A1147

Alternate gene names: 83592483

Gene position: 1354127-1355311 (Clockwise)

Preceding gene: 83592482

Following gene: 83592491

Centisome position: 31.11

GC content: 65.49

Gene sequence:

>1185_bases
ATGAGCGATGCGCTTCTTCCGGTGTTTTCACCGGCATCCGTGCTGTTCGACCATGGCGAAGGGGCTTGGTTGGTCGCGGC
CAATGGCGAGCGCTATCTTGATTTCGGCGCGGGCATCGCGGTTAACGCCCTGGGCTATTCCCATCCGCATCTGGTTGGGG
CGTTGGAACGGCAAGGCCGCAAGCTTTGGCACTTGTCGAATGTCTATCGGATTTCCGAAGCGGAGAGACTGGCCGAGCGC
CTGACGGCCGCCTGCTTCGCCGACGTCGCGTTCTTTGCGAACTCCGGGGCCGAAGCCAATGAATGCGCGATCAAGATCGC
CCGGCGCCACCACGACGCCCATGGCCGTCCCGAGCGCTGGCGCATCATCACCTTTGACGGCGCCTTTCACGGGCGAACGC
TGGCCACGATGGCCGCTGGCGGCAACCGGAAATATCTCGATGGCTTTGGCCCCGCGGTCGATGGCTTCGACCAATGCCCG
CTTGAAGACATCGAGGCGGTCCGCGCCCGCGTCGGGCCACGGACCGCCGCCCTTATGATCGAACCCATTCAGGGGGAAAG
CGGCATTCGGCCGGTGAGCCACGGCTTCTTGCGCCAGCTTCGCGAGCTTTGCGACGAACGCGGCCTTTTGCTGATCTTCG
ATGAAATACAGTGCGGCATGGCCCGCACCGGCCATCTCTTCGCCCATCAGGAAGCCGGCGTCGTCCCCGATATCATGAGT
CTGGCCAAGGGCCTCGGCGGCGGCTTCCCGATCGGCGCCTGCCTCGCCACCCGCGGTGCGGCGTTCGGCATGAGGCCCGG
CGCGCATGGTTCGACCTTTGGCGGAAATCCGCTTGCCGGAGCCGTCGCCAATGCGGTGCTCGACATCGTGATGGACGATG
GGGTGCTCGCGGAAATCCGCCGCAAGAGCGCTTTGCTGCGCGGGCTGCTGGAAGAGCTGGCCGGGCGTTATCCCGACCTC
CTTGTCGAGGTGCGCGGGCGCGGCCTGATGCTCGGTCTCAAAACCACGCGGCCATCGCCGGAAATCGTCGAAGCGCTGCG
CGCGCGGGCGAAGGTGCTGACGATCGCCGCAGGCGACACCGTAACCCGCGTGCTACCGCCGCTGATCGTCACCGACAAGG
ACATCCGCCTGTTCGCCGAGCGCTGTGACGAAACGTTCGCCGGTCTCTCAAGGCCTGCGGCATAG

Upstream 100 bases:

>100_bases
TCGCGGCGCTCGTCGCGATCCGTCAGGAATTCCCGCGTTGGCGAGAACTGGCACAGGCGGCGCGACCCGACCCTTCCGCC
CTGGGCAGGGGGGACGTAGC

Downstream 100 bases:

>100_bases
GGGGGAATAGGCTGCGGAACACCCCCCTTTCCCCTGACAGCCGCCGCCTTGAGCAGATAAGTTCGATCCCGCGACCTTGG
GGTTACGGAGCCTTCTTTGG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSDALLPVFSPASVLFDHGEGAWLVAANGERYLDFGAGIAVNALGYSHPHLVGALERQGRKLWHLSNVYRISEAERLAER
LTAACFADVAFFANSGAEANECAIKIARRHHDAHGRPERWRIITFDGAFHGRTLATMAAGGNRKYLDGFGPAVDGFDQCP
LEDIEAVRARVGPRTAALMIEPIQGESGIRPVSHGFLRQLRELCDERGLLLIFDEIQCGMARTGHLFAHQEAGVVPDIMS
LAKGLGGGFPIGACLATRGAAFGMRPGAHGSTFGGNPLAGAVANAVLDIVMDDGVLAEIRRKSALLRGLLEELAGRYPDL
LVEVRGRGLMLGLKTTRPSPEIVEALRARAKVLTIAAGDTVTRVLPPLIVTDKDIRLFAERCDETFAGLSRPAA

Sequences:

>Translated_394_residues
MSDALLPVFSPASVLFDHGEGAWLVAANGERYLDFGAGIAVNALGYSHPHLVGALERQGRKLWHLSNVYRISEAERLAER
LTAACFADVAFFANSGAEANECAIKIARRHHDAHGRPERWRIITFDGAFHGRTLATMAAGGNRKYLDGFGPAVDGFDQCP
LEDIEAVRARVGPRTAALMIEPIQGESGIRPVSHGFLRQLRELCDERGLLLIFDEIQCGMARTGHLFAHQEAGVVPDIMS
LAKGLGGGFPIGACLATRGAAFGMRPGAHGSTFGGNPLAGAVANAVLDIVMDDGVLAEIRRKSALLRGLLEELAGRYPDL
LVEVRGRGLMLGLKTTRPSPEIVEALRARAKVLTIAAGDTVTRVLPPLIVTDKDIRLFAERCDETFAGLSRPAA
>Mature_393_residues
SDALLPVFSPASVLFDHGEGAWLVAANGERYLDFGAGIAVNALGYSHPHLVGALERQGRKLWHLSNVYRISEAERLAERL
TAACFADVAFFANSGAEANECAIKIARRHHDAHGRPERWRIITFDGAFHGRTLATMAAGGNRKYLDGFGPAVDGFDQCPL
EDIEAVRARVGPRTAALMIEPIQGESGIRPVSHGFLRQLRELCDERGLLLIFDEIQCGMARTGHLFAHQEAGVVPDIMSL
AKGLGGGFPIGACLATRGAAFGMRPGAHGSTFGGNPLAGAVANAVLDIVMDDGVLAEIRRKSALLRGLLEELAGRYPDLL
VEVRGRGLMLGLKTTRPSPEIVEALRARAKVLTIAAGDTVTRVLPPLIVTDKDIRLFAERCDETFAGLSRPAA

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=385, Percent_Identity=33.7662337662338, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=36.3333333333333, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI13994255, Length=421, Percent_Identity=30.4038004750594, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI37574042, Length=411, Percent_Identity=27.007299270073, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI226442709, Length=390, Percent_Identity=26.6666666666667, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI226442705, Length=411, Percent_Identity=26.2773722627737, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI188536080, Length=422, Percent_Identity=27.0142180094787, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI38679950, Length=422, Percent_Identity=27.0142180094787, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI38679946, Length=422, Percent_Identity=27.0142180094787, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI24119277, Length=407, Percent_Identity=26.7813267813268, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI1789759, Length=381, Percent_Identity=44.6194225721785, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1788044, Length=387, Percent_Identity=42.6356589147287, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI145693181, Length=398, Percent_Identity=33.6683417085427, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1789016, Length=404, Percent_Identity=32.4257425742574, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1787560, Length=392, Percent_Identity=35.969387755102, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1786991, Length=359, Percent_Identity=33.4261838440111, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786349, Length=314, Percent_Identity=30.5732484076433, Blast_Score=108, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=390, Percent_Identity=31.2820512820513, Blast_Score=197, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI32564660, Length=435, Percent_Identity=29.4252873563218, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25144274, Length=275, Percent_Identity=32.3636363636364, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=441, Percent_Identity=25.1700680272109, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17541228, Length=441, Percent_Identity=25.6235827664399, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=163, Percent_Identity=28.2208588957055, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=380, Percent_Identity=36.8421052631579, Blast_Score=254, Evalue=1e-68,
Organism=Saccharomyces cerevisiae, GI6323470, Length=399, Percent_Identity=29.8245614035088, Blast_Score=168, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324386, Length=395, Percent_Identity=25.5696202531646, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=371, Percent_Identity=26.4150943396226, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357415, Length=374, Percent_Identity=32.3529411764706, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI161085790, Length=427, Percent_Identity=29.7423887587822, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28574759, Length=418, Percent_Identity=29.6650717703349, Blast_Score=161, Evalue=9e-40,
Organism=Drosophila melanogaster, GI21356575, Length=408, Percent_Identity=27.2058823529412, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281366494, Length=440, Percent_Identity=23.4090909090909, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24667139, Length=440, Percent_Identity=23.4090909090909, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24667143, Length=440, Percent_Identity=23.4090909090909, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42226; Mature: 42095

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDALLPVFSPASVLFDHGEGAWLVAANGERYLDFGAGIAVNALGYSHPHLVGALERQGR
CCCCCCCCCCCHHHEEECCCCEEEEEECCCEEEEECCCEEEECCCCCCCHHHHHHHHCCC
KLWHLSNVYRISEAERLAERLTAACFADVAFFANSGAEANECAIKIARRHHDAHGRPERW
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCE
RIITFDGAFHGRTLATMAAGGNRKYLDGFGPAVDGFDQCPLEDIEAVRARVGPRTAALMI
EEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEE
EPIQGESGIRPVSHGFLRQLRELCDERGLLLIFDEIQCGMARTGHLFAHQEAGVVPDIMS
EECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCCCCHHHHH
LAKGLGGGFPIGACLATRGAAFGMRPGAHGSTFGGNPLAGAVANAVLDIVMDDGVLAEIR
HHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
RKSALLRGLLEELAGRYPDLLVEVRGRGLMLGLKTTRPSPEIVEALRARAKVLTIAAGDT
HHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHEEEEEECCCH
VTRVLPPLIVTDKDIRLFAERCDETFAGLSRPAA
HHHHCCCEEECCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SDALLPVFSPASVLFDHGEGAWLVAANGERYLDFGAGIAVNALGYSHPHLVGALERQGR
CCCCCCCCCCHHHEEECCCCEEEEEECCCEEEEECCCEEEECCCCCCCHHHHHHHHCCC
KLWHLSNVYRISEAERLAERLTAACFADVAFFANSGAEANECAIKIARRHHDAHGRPERW
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCE
RIITFDGAFHGRTLATMAAGGNRKYLDGFGPAVDGFDQCPLEDIEAVRARVGPRTAALMI
EEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEE
EPIQGESGIRPVSHGFLRQLRELCDERGLLLIFDEIQCGMARTGHLFAHQEAGVVPDIMS
EECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCCCCHHHHH
LAKGLGGGFPIGACLATRGAAFGMRPGAHGSTFGGNPLAGAVANAVLDIVMDDGVLAEIR
HHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
RKSALLRGLLEELAGRYPDLLVEVRGRGLMLGLKTTRPSPEIVEALRARAKVLTIAAGDT
HHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHEEEEEECCCH
VTRVLPPLIVTDKDIRLFAERCDETFAGLSRPAA
HHHHCCCEEECCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]