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The map label for this gene is tolQ [H]

Identifier: 83592427

GI number: 83592427

Start: 1280130

End: 1281056

Strand: Direct

Name: tolQ [H]

Synonym: Rru_A1091

Alternate gene names: 83592427

Gene position: 1280130-1281056 (Clockwise)

Preceding gene: 83592426

Following gene: 83592428

Centisome position: 29.41

GC content: 66.45

Gene sequence:

>927_bases
ATGGACTACCTCTCCATGGACGCGATAACCCAGCTGACCGGCCAGATGGCCAGCCACTTGGGCATCGCCGGGCTCGATCA
TCTTGGCCAGACGGCCTCCCGCTTGGGGCTGATGCTGGAGCGGGGCCTTGACGTCCAGTCCAGTCCGCCCCTGCCCGCGG
CCGCGCCGTCTGTGCCCGTGGCCAGCGAAATTCTGCCCAATGCCAGCGGCGTCGGCGCCGCCGCGCCCGGGGCGACGATG
GGCGAGAAGCCGTCGCTGTCGGCTTGGTCGATGTTCTGGCAGGCCGATATCATCGTCAAGATGGTGATGCTGAGCCTGGT
CGGCGCCAGCATCTGGTCGTGGACCATCGTTTTCGAAAAGATCGTTCGCTTACGCGATCTCAACAAGAAAGCCGAGCAGT
TCGAAGAGAAATTCTGGTCGGGCGGCTCGCTTGAAGACCTGTTCGACCGCATCGGCCAGCGGCCGCGCGATCCGATGACC
GCGGTGTTCGTGGCCGCCATGCGCGAATGGCGTCACAGCGCCCAGCGCCGCAACGGCGCCGCTGGTGCGCGCGCCATGCT
GGCCCAGCGCGTCGAGCGGGTGATGGGCATCACCCAGAACCGCGAGCTGGAAACCCTGGAACGCCGGCTGGGCTTCCTGG
CCTCGACCGGCGCCGTCGCGCCCTTCGTCGGGCTGTTTGGCACGGTCTGGGGCATCATGAACAGCTTCCACGCCATCGGT
ATGTCCAATGACACCAGTCTGGCGACGGTGGCCCCCGGTATCGCCGAGGCGCTGTTCGCCACGGCTTTGGGACTGGTCGC
CGCCATCCCGGCGGTGATCGCCTATAACAAGCTTTCCGCCGATATCGACCGCTATGCCGGCCGCCTGGAGGCGTTCTCCG
GGGAATTCGGGGCGATCCTCGGCCGTCAGCTCGACGAGCGCGAGTAA

Upstream 100 bases:

>100_bases
CTGTCGCTGAAGGCCGGCGTTCCCATCCGCATTCCCGCCATCATGCGGGAGAAACTTGTACCAGGAAACGGCGACTGACC
ACACGGACACGGGGTTGATT

Downstream 100 bases:

>100_bases
TCGGGCGCCGATCAGGAGAACGATGAGATGGGTGCCTCGGTCCAACCCCGACGCGGCGGTCGCCGCAAGCGCAGTCACCA
GATGAGCGACATCAACGTCA

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MDYLSMDAITQLTGQMASHLGIAGLDHLGQTASRLGLMLERGLDVQSSPPLPAAAPSVPVASEILPNASGVGAAAPGATM
GEKPSLSAWSMFWQADIIVKMVMLSLVGASIWSWTIVFEKIVRLRDLNKKAEQFEEKFWSGGSLEDLFDRIGQRPRDPMT
AVFVAAMREWRHSAQRRNGAAGARAMLAQRVERVMGITQNRELETLERRLGFLASTGAVAPFVGLFGTVWGIMNSFHAIG
MSNDTSLATVAPGIAEALFATALGLVAAIPAVIAYNKLSADIDRYAGRLEAFSGEFGAILGRQLDERE

Sequences:

>Translated_308_residues
MDYLSMDAITQLTGQMASHLGIAGLDHLGQTASRLGLMLERGLDVQSSPPLPAAAPSVPVASEILPNASGVGAAAPGATM
GEKPSLSAWSMFWQADIIVKMVMLSLVGASIWSWTIVFEKIVRLRDLNKKAEQFEEKFWSGGSLEDLFDRIGQRPRDPMT
AVFVAAMREWRHSAQRRNGAAGARAMLAQRVERVMGITQNRELETLERRLGFLASTGAVAPFVGLFGTVWGIMNSFHAIG
MSNDTSLATVAPGIAEALFATALGLVAAIPAVIAYNKLSADIDRYAGRLEAFSGEFGAILGRQLDERE
>Mature_308_residues
MDYLSMDAITQLTGQMASHLGIAGLDHLGQTASRLGLMLERGLDVQSSPPLPAAAPSVPVASEILPNASGVGAAAPGATM
GEKPSLSAWSMFWQADIIVKMVMLSLVGASIWSWTIVFEKIVRLRDLNKKAEQFEEKFWSGGSLEDLFDRIGQRPRDPMT
AVFVAAMREWRHSAQRRNGAAGARAMLAQRVERVMGITQNRELETLERRLGFLASTGAVAPFVGLFGTVWGIMNSFHAIG
MSNDTSLATVAPGIAEALFATALGLVAAIPAVIAYNKLSADIDRYAGRLEAFSGEFGAILGRQLDERE

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=216, Percent_Identity=43.0555555555556, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1789381, Length=223, Percent_Identity=35.8744394618834, Blast_Score=134, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 33106; Mature: 33106

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCC
>Mature Secondary Structure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HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]