BacMap

Definition	Rhodospirillum rubrum ATCC 11170 chromosome, complete genome.
Accession	NC_007643
Length	4,352,825

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The map label for this gene is hbdH1 [H]

Identifier: 83592393

GI number: 83592393

Start: 1251265

End: 1252044

Strand: Direct

Name: hbdH1 [H]

Synonym: Rru_A1057

Alternate gene names: 83592393

Gene position: 1251265-1252044 (Clockwise)

Preceding gene: 83592390

Following gene: 83592394

Centisome position: 28.75

GC content: 65.77

Gene sequence:

>780_bases
ATGAAAGGCAAATGCGCAGTGGTGACCGGGTCGACCAGCGGAATCGGCCTTGGCATCGCCCGGGCCCTGGCCGGGCAGGG
CGTCGATATCGTGTTGAACGGCTTCGGGGCGCCCGAGGCGATCGAGGATATCCGCAAGGACATCGAGACCAGTTTTTCGG
TGCGCGCCATCCATATCGACGCCGATCTGGCGCAGGGCGAGGCCTGCCGCGCTCTAATCGCTCAGGCGATCGCCGAAATG
GGGCAGGTCGATATCCTGGTCAATAACGCCGGCATTCAGCATACCAGCGACATCGTCGATTTTCCGCCCGAGCGCTGGAA
TAGCGTCATCGCCATCAATCTTTCAGCGGTCTTCCATTGCACGGCGGCGGCCTTGCCGGGAATGCGCGAGCGCGATTGGG
GGCGGGTGATCAATGTCGCCAGCGCCCATGGACTGGTGGCCAGCGTCGGCAAGGCCGCCTATGTGGCGGCCAAGCACGGG
GTCCTTGGGCTGACCAAGGTCGCCGCCCTGGAAAACGCCACCCGCCACATCACCGTCAACGCCATCTGCCCGGGGTGGGT
GCTGACGCCGCTGGTGCAGGCCCAGATCGACGCCCGCGCCGCCCGCGACGGCGTTACCGTCGAGCGGGCGACCGTCGATT
TGCTCAGCGAAAAGCAGCCGACGCGGCGCTTCGTCACCCCCGAGCAGATCGGCGCCATGGCGGTTTATCTGTGTTCCGAG
GCGGCCGATACGCTGACCGGCGTGCCGTTGTCGATCGATGGCGGCTGGACCGCGCAATAG

Upstream 100 bases:

>100_bases
GAGAGGTTAAAAAGCCGCAAGGGTTACCCTACCTAAGGTGAGTCTAGTCGCCTTGCGGACAGCCGCAAGGAGCAATGGCT
CATCATGGGAGAGGGGATCG

Downstream 100 bases:

>100_bases
GGGACCGGCATGCCCAAGCAGTCCATCGACCGGCGCGAGGCTTACCCGTTTTTTCTGCCCATCCAAATGCGCTGGGGCGA
CCTCGACCCGTTCCACCATG

Product: 3-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKGKCAVVTGSTSGIGLGIARALAGQGVDIVLNGFGAPEAIEDIRKDIETSFSVRAIHIDADLAQGEACRALIAQAIAEM
GQVDILVNNAGIQHTSDIVDFPPERWNSVIAINLSAVFHCTAAALPGMRERDWGRVINVASAHGLVASVGKAAYVAAKHG
VLGLTKVAALENATRHITVNAICPGWVLTPLVQAQIDARAARDGVTVERATVDLLSEKQPTRRFVTPEQIGAMAVYLCSE
AADTLTGVPLSIDGGWTAQ

Sequences:

>Translated_259_residues
MKGKCAVVTGSTSGIGLGIARALAGQGVDIVLNGFGAPEAIEDIRKDIETSFSVRAIHIDADLAQGEACRALIAQAIAEM
GQVDILVNNAGIQHTSDIVDFPPERWNSVIAINLSAVFHCTAAALPGMRERDWGRVINVASAHGLVASVGKAAYVAAKHG
VLGLTKVAALENATRHITVNAICPGWVLTPLVQAQIDARAARDGVTVERATVDLLSEKQPTRRFVTPEQIGAMAVYLCSE
AADTLTGVPLSIDGGWTAQ
>Mature_259_residues
MKGKCAVVTGSTSGIGLGIARALAGQGVDIVLNGFGAPEAIEDIRKDIETSFSVRAIHIDADLAQGEACRALIAQAIAEM
GQVDILVNNAGIQHTSDIVDFPPERWNSVIAINLSAVFHCTAAALPGMRERDWGRVINVASAHGLVASVGKAAYVAAKHG
VLGLTKVAALENATRHITVNAICPGWVLTPLVQAQIDARAARDGVTVERATVDLLSEKQPTRRFVTPEQIGAMAVYLCSE
AADTLTGVPLSIDGGWTAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=186, Percent_Identity=34.9462365591398, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=29.6577946768061, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI32483357, Length=264, Percent_Identity=30.3030303030303, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI4504505, Length=273, Percent_Identity=26.3736263736264, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=27.2030651340996, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=30, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI59889578, Length=213, Percent_Identity=32.3943661971831, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI20149619, Length=210, Percent_Identity=29.5238095238095, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5031737, Length=258, Percent_Identity=28.2945736434109, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=29.4797687861272, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=30.0518134715026, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI126723191, Length=206, Percent_Identity=30.0970873786408, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40254992, Length=255, Percent_Identity=28.2352941176471, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=32.1052631578947, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705855, Length=195, Percent_Identity=30.2564102564103, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI226371731, Length=191, Percent_Identity=28.7958115183246, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI126723750, Length=267, Percent_Identity=26.5917602996255, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4758504, Length=208, Percent_Identity=32.2115384615385, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI109715829, Length=257, Percent_Identity=27.2373540856031, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI7705925, Length=264, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI40807363, Length=194, Percent_Identity=27.8350515463918, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI142976729, Length=197, Percent_Identity=28.9340101522843, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4503817, Length=194, Percent_Identity=28.8659793814433, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=23.921568627451, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI83715985, Length=181, Percent_Identity=31.4917127071823, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789208, Length=261, Percent_Identity=35.2490421455939, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=35.2713178294574, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1787335, Length=256, Percent_Identity=31.25, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=31.0077519379845, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=32.6771653543307, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=30.6513409961686, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=27.906976744186, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=28.2258064516129, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=28.1853281853282, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI2367365, Length=257, Percent_Identity=26.0700389105058, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=28.6274509803922, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787820, Length=158, Percent_Identity=29.746835443038, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=26.0536398467433, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=263, Percent_Identity=30.7984790874525, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=27.9693486590038, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=263, Percent_Identity=29.6577946768061, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=261, Percent_Identity=30.2681992337165, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=269, Percent_Identity=27.1375464684015, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17564282, Length=199, Percent_Identity=31.6582914572864, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17568967, Length=207, Percent_Identity=29.4685990338164, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=29.3814432989691, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=29.6875, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=28.2352941176471, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=269, Percent_Identity=29.368029739777, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=194, Percent_Identity=27.8350515463918, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=28.6245353159851, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=27.0676691729323, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=201, Percent_Identity=30.3482587064677, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=199, Percent_Identity=31.1557788944724, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=25.5725190839695, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=197, Percent_Identity=28.9340101522843, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=24.907063197026, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17558006, Length=217, Percent_Identity=28.110599078341, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=200, Percent_Identity=28.5, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25152911, Length=230, Percent_Identity=29.1304347826087, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17555612, Length=265, Percent_Identity=27.9245283018868, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=27.0676691729323, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=209, Percent_Identity=30.1435406698565, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=33.5078534031414, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=29.6875, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=30.1158301158301, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI18859837, Length=269, Percent_Identity=30.4832713754647, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=30.7392996108949, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24639444, Length=262, Percent_Identity=28.2442748091603, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357041, Length=261, Percent_Identity=27.9693486590038, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28571526, Length=261, Percent_Identity=29.5019157088123, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21355319, Length=263, Percent_Identity=27.3764258555133, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24584744, Length=192, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28574402, Length=192, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=33.5078534031414, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI161076933, Length=191, Percent_Identity=33.5078534031414, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=27.8350515463918, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24640442, Length=194, Percent_Identity=30.9278350515464, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24649181, Length=190, Percent_Identity=28.9473684210526, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24643142, Length=260, Percent_Identity=26.5384615384615, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571387, Length=208, Percent_Identity=27.8846153846154, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221331216, Length=203, Percent_Identity=29.064039408867, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24665247, Length=203, Percent_Identity=29.064039408867, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24665243, Length=203, Percent_Identity=29.064039408867, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221331218, Length=203, Percent_Identity=29.064039408867, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007236, Length=197, Percent_Identity=28.4263959390863, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=29.3413173652695, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17737361, Length=206, Percent_Identity=27.1844660194175, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641232, Length=207, Percent_Identity=28.5024154589372, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24644337, Length=178, Percent_Identity=29.7752808988764, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI281364494, Length=207, Percent_Identity=28.5024154589372, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 27051; Mature: 27051

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGKCAVVTGSTSGIGLGIARALAGQGVDIVLNGFGAPEAIEDIRKDIETSFSVRAIHID
CCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEEE
ADLAQGEACRALIAQAIAEMGQVDILVNNAGIQHTSDIVDFPPERWNSVIAINLSAVFHC
CCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHCCCHHHCCCEEEEEHHHHHHH
TAAALPGMRERDWGRVINVASAHGLVASVGKAAYVAAKHGVLGLTKVAALENATRHITVN
HHHHCCCCCCCCCHHEEEHHHHHHHHHHHCHHHEEHHHCCCHHHHHHHHHCCCCEEEEEE
AICPGWVLTPLVQAQIDARAARDGVTVERATVDLLSEKQPTRRFVTPEQIGAMAVYLCSE
EECCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
AADTLTGVPLSIDGGWTAQ
HHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MKGKCAVVTGSTSGIGLGIARALAGQGVDIVLNGFGAPEAIEDIRKDIETSFSVRAIHID
CCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEEE
ADLAQGEACRALIAQAIAEMGQVDILVNNAGIQHTSDIVDFPPERWNSVIAINLSAVFHC
CCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHCCCHHHCCCEEEEEHHHHHHH
TAAALPGMRERDWGRVINVASAHGLVASVGKAAYVAAKHGVLGLTKVAALENATRHITVN
HHHHCCCCCCCCCHHEEEHHHHHHHHHHHCHHHEEHHHCCCHHHHHHHHHCCCCEEEEEE
AICPGWVLTPLVQAQIDARAARDGVTVERATVDLLSEKQPTRRFVTPEQIGAMAVYLCSE
EECCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
AADTLTGVPLSIDGGWTAQ
HHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA