Click here to switch to the map view.

The map label for this gene is yesM [H]

Identifier: 83592254

GI number: 83592254

Start: 1091959

End: 1093290

Strand: Direct

Name: yesM [H]

Synonym: Rru_A0918

Alternate gene names: 83592254

Gene position: 1091959-1093290 (Clockwise)

Preceding gene: 83592253

Following gene: 83592255

Centisome position: 25.09

GC content: 61.34

Gene sequence:

>1332_bases
ATGAACGCGTTGCGCCTTGAAGATCTGATCAGCGTGGAAATGCTGCAGAAGGTGCAGGATAATTTCAGCGCCGCCGTGGG
CATCGCGATGATCATCGTCGACGAGCGCGGCACCCCCGTGACCCGGCCCAGCAATTTTTCCGCCTTCTGCCAGACCATCA
GAACCTCGGCGGCGCGGCGCGATCAATGCTTTCAGTGCGACGATGACGGCGGTCGCCGCGCCATGGCGATGGGCGAACCC
AGCATCTATCAATGCCACTGCGGACTGGTCGATTTCGCCGCGCCGATCATCGTGCGCGACCAGTATCTGGGGGCGGTGAT
CTCCGGTCAGGTCCGCCTGCGCCAGGGCCACGAGGTCACCTTGGAATACATCGCGCCGCCCGATGAGTCCTGGCGCCAGG
ACGCCCATCTGATCGCCCTGCGCGAGAAGATCACCGAAATCCCCTATGTGAAGCTGCGTTCGGCCGCCTATACGCTCTAT
CACCTCGCCGCCTATCTGGTGGAGGAGAGCTATTCCAACGCCGTCAGCCAGGAACTGAGCGCCAAGAACCTGAAGCTGAT
GGAGGAATCAAAGCGTCGGGTGGAACTGGAAAAGTCGCTGCGCGAGGCCGAACTCCAGGCTTTGTCCTATCAGGTCAATC
CGCATTTCCTGTTCAACGTCCTTAACACCATCGGCCGTCTGGCGCTGAAGGAACACGCGCCGAAGACCGAGGACATGCTC
TACGCCTTCGCCGACATGATGCGCTACGTGCTCAAGAAAAGCCGGTCGCAGATCGTCTCGCTGCAGACCGAGGTCGGTCA
TGTGCGCAATTACCTGCATATCCAGAAGGTGCGCATGGGCGACCGTTTCACCTTCACCATGGATGTGCCGGCCAAATACG
ACGGCATCTTGTGCCCCTTCATGGTTCTTCACCCGATCGTCGAGAACAGCATCAACTACGCCATCGAGCCCCATGAGGCC
GATGGGCGGATCGAGATCACCGCCCGCGATGACGGCCTGAACATGATTTTGCGGGTGGTCGATAACGGCGATGGCGTCTC
GCCCGAGTTGGTGCGCGCCGCGCTGGACGGAGTGGCCGAACCCCATGGCCGCACCAGCATCGGCCTGCACAATGTGGACA
GCCGTCTGCGCCATTTCTTCGGCCCCGACTATGGGCTGACGGTCGAAAGCCCAGCCACTCCGGGGGGGCGGCACGGTCGT
CGAGATGCGCTTTCCCCTGGACTTCGATCCCTGCGGCACCTGAACGCCTGCGCCGAGGAGAGACGGCTATGTACGGCATT
GTCATTGTTGAAGACGAGGAACTCGAGCGCCAGGCGCTGCGCACCATTCTAA

Upstream 100 bases:

>100_bases
GACCGTGTTGACGCCTTGCGCGCTGTTTGCGGGCTGTGAGTTGATCTGATCGGACGGGGCTGGACCTGGAGGAGCCAAAA
CAAAAAAGAGGATGCGGGGA

Downstream 100 bases:

>100_bases
CCGAGAATATCGACGGCATCCGCATTCTGGGCGAAGCGCGCACCGGCACCGAGGCGGTGGCGCTGATCGACAGCTGCGAG
ATCGATCTGATGCTGGTCGA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MNALRLEDLISVEMLQKVQDNFSAAVGIAMIIVDERGTPVTRPSNFSAFCQTIRTSAARRDQCFQCDDDGGRRAMAMGEP
SIYQCHCGLVDFAAPIIVRDQYLGAVISGQVRLRQGHEVTLEYIAPPDESWRQDAHLIALREKITEIPYVKLRSAAYTLY
HLAAYLVEESYSNAVSQELSAKNLKLMEESKRRVELEKSLREAELQALSYQVNPHFLFNVLNTIGRLALKEHAPKTEDML
YAFADMMRYVLKKSRSQIVSLQTEVGHVRNYLHIQKVRMGDRFTFTMDVPAKYDGILCPFMVLHPIVENSINYAIEPHEA
DGRIEITARDDGLNMILRVVDNGDGVSPELVRAALDGVAEPHGRTSIGLHNVDSRLRHFFGPDYGLTVESPATPGGRHGR
RDALSPGLRSLRHLNACAEERRLCTALSLLKTRNSSARRCAPF

Sequences:

>Translated_443_residues
MNALRLEDLISVEMLQKVQDNFSAAVGIAMIIVDERGTPVTRPSNFSAFCQTIRTSAARRDQCFQCDDDGGRRAMAMGEP
SIYQCHCGLVDFAAPIIVRDQYLGAVISGQVRLRQGHEVTLEYIAPPDESWRQDAHLIALREKITEIPYVKLRSAAYTLY
HLAAYLVEESYSNAVSQELSAKNLKLMEESKRRVELEKSLREAELQALSYQVNPHFLFNVLNTIGRLALKEHAPKTEDML
YAFADMMRYVLKKSRSQIVSLQTEVGHVRNYLHIQKVRMGDRFTFTMDVPAKYDGILCPFMVLHPIVENSINYAIEPHEA
DGRIEITARDDGLNMILRVVDNGDGVSPELVRAALDGVAEPHGRTSIGLHNVDSRLRHFFGPDYGLTVESPATPGGRHGR
RDALSPGLRSLRHLNACAEERRLCTALSLLKTRNSSARRCAPF
>Mature_443_residues
MNALRLEDLISVEMLQKVQDNFSAAVGIAMIIVDERGTPVTRPSNFSAFCQTIRTSAARRDQCFQCDDDGGRRAMAMGEP
SIYQCHCGLVDFAAPIIVRDQYLGAVISGQVRLRQGHEVTLEYIAPPDESWRQDAHLIALREKITEIPYVKLRSAAYTLY
HLAAYLVEESYSNAVSQELSAKNLKLMEESKRRVELEKSLREAELQALSYQVNPHFLFNVLNTIGRLALKEHAPKTEDML
YAFADMMRYVLKKSRSQIVSLQTEVGHVRNYLHIQKVRMGDRFTFTMDVPAKYDGILCPFMVLHPIVENSINYAIEPHEA
DGRIEITARDDGLNMILRVVDNGDGVSPELVRAALDGVAEPHGRTSIGLHNVDSRLRHFFGPDYGLTVESPATPGGRHGR
RDALSPGLRSLRHLNACAEERRLCTALSLLKTRNSSARRCAPF

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=223, Percent_Identity=31.390134529148, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788723, Length=205, Percent_Identity=26.3414634146341, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49752; Mature: 49752

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALRLEDLISVEMLQKVQDNFSAAVGIAMIIVDERGTPVTRPSNFSAFCQTIRTSAARR
CCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHC
DQCFQCDDDGGRRAMAMGEPSIYQCHCGLVDFAAPIIVRDQYLGAVISGQVRLRQGHEVT
CCCCCCCCCCCCEEEECCCCCEEEEECCHHHHHCHHHHHHHHHHHHHCCCEEEECCCEEE
LEYIAPPDESWRQDAHLIALREKITEIPYVKLRSAAYTLYHLAAYLVEESYSNAVSQELS
EEEECCCCHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKNLKLMEESKRRVELEKSLREAELQALSYQVNPHFLFNVLNTIGRLALKEHAPKTEDML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCHHHHH
YAFADMMRYVLKKSRSQIVSLQTEVGHVRNYLHIQKVRMGDRFTFTMDVPAKYDGILCPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEECCCCCCCCHHHH
MVLHPIVENSINYAIEPHEADGRIEITARDDGLNMILRVVDNGDGVSPELVRAALDGVAE
HHHHHHHHCCCCEEECCCCCCCEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHCCC
PHGRTSIGLHNVDSRLRHFFGPDYGLTVESPATPGGRHGRRDALSPGLRSLRHLNACAEE
CCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHH
RRLCTALSLLKTRNSSARRCAPF
HHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNALRLEDLISVEMLQKVQDNFSAAVGIAMIIVDERGTPVTRPSNFSAFCQTIRTSAARR
CCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHC
DQCFQCDDDGGRRAMAMGEPSIYQCHCGLVDFAAPIIVRDQYLGAVISGQVRLRQGHEVT
CCCCCCCCCCCCEEEECCCCCEEEEECCHHHHHCHHHHHHHHHHHHHCCCEEEECCCEEE
LEYIAPPDESWRQDAHLIALREKITEIPYVKLRSAAYTLYHLAAYLVEESYSNAVSQELS
EEEECCCCHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKNLKLMEESKRRVELEKSLREAELQALSYQVNPHFLFNVLNTIGRLALKEHAPKTEDML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCHHHHH
YAFADMMRYVLKKSRSQIVSLQTEVGHVRNYLHIQKVRMGDRFTFTMDVPAKYDGILCPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEECCCCCCCCHHHH
MVLHPIVENSINYAIEPHEADGRIEITARDDGLNMILRVVDNGDGVSPELVRAALDGVAE
HHHHHHHHCCCCEEECCCCCCCEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHCCC
PHGRTSIGLHNVDSRLRHFFGPDYGLTVESPATPGGRHGRRDALSPGLRSLRHLNACAEE
CCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHH
RRLCTALSLLKTRNSSARRCAPF
HHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]