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The map label for this gene is hemK [H]

Identifier: 83592090

GI number: 83592090

Start: 880072

End: 881049

Strand: Direct

Name: hemK [H]

Synonym: Rru_A0751

Alternate gene names: 83592090

Gene position: 880072-881049 (Clockwise)

Preceding gene: 83592089

Following gene: 83592091

Centisome position: 20.22

GC content: 71.27

Gene sequence:

>978_bases
GTGAGCGACGGCGACGGCGGCGGGGAGCAAGGGGGCGGCGGTCCGGCCGAGGCGGAGGAGTCCGCCCTGGTATTGGGCCG
GTTGCTCGACCGTGGCGCCTGGCGGCTGAAAGTCGCCGGCGTCGAAAAGCCCCGCCGCGATGCCCGCCTGCTGGCCGGCC
ATGTCCTTGGCCTGTCGCCGGGCGCGGTGCTGCTGGCCGATGACCGGGTGGTCACCCCCGAGGAAGCCCAGGCCCTGGAG
GCGGTGATCGCCCGCCGCGAAACCCGCGAGCCGGTCTCGCGCATCCTCGGGCATCGCGGGTTCTGGCGCTTCGATCTGGC
GCTGGGCGCCGATACCCTGGACCCCCGCCCCGATACGGAGACCCTGGTCGAGGCCGGTCTGGCCGTGCTGGAAGGCTGCG
GCGGGCGCATCCTTGATCTGGGCACCGGCAGTGGCTGCATTCTGCTGGCCTTGCTTGCCGATCGTCCCGGGGCGATCGGC
CTGGGGATCGATATCGCCCCGGGGGCGGTGCGGGTGGCCCTGCGCAACGCCCGCGCCCTGGGTCTGGAGCGCCGCGCCCT
GTTCGCCGTCGGCGATTGGGCGGCGGCGGTCGCTGGCCCCTTCGATCTGATCGTGTCCAATCCCCCCTATATCCCCTCGG
CCGATATCGCCGCCCTGGAGCCCGAGGTCGCCCGCTTCGATCCGTCGCGCGCCCTGGACGGCGGGGCCGACGGCCTTGAC
CCTTATCGTATCTTGGCCGCCCAGGTGCCGGCGCTGCTGGCGCCGGCCGGGGTTCTGGCCGTCGAATTCGGTCAGGGACA
AGCCAGGGATGTGGCCGGGCTCTTGGAAGTGGGCGGTTTATGCCCATATGAGATCAAGAAGGATCTTTCCGGGGAAGAGC
GCTGTTTGCTCGCCCGGCGCCGAGCGGCGGGTCCTTTGCCCCCTATCCATATCGATGCCAAGCCGTCGGCACCCGGGAAC
GGTCCGACAAAGGCGTGA

Upstream 100 bases:

>100_bases
TGCACCGCTTGCCCGAGGTTCTGGCCGGAACCGCCCTTGACGAGGTGATCGAGCCGCTGATCGCCGAGGATCAGGCGACG
CGGATGGCGGAGATCGGCGG

Downstream 100 bases:

>100_bases
GACGGTCTTCGCTTTGACGGAAAAAAGCGCTGGAAAAAAGGGTTCGGGGCGAATAGGGTGCAATTGGCACGCGGCGGATT
GACCGGTGGGGATACGAAGG

Product: modification methylase HemK

Products: NA

Alternate protein names: M.MloHemKP [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSDGDGGGEQGGGGPAEAEESALVLGRLLDRGAWRLKVAGVEKPRRDARLLAGHVLGLSPGAVLLADDRVVTPEEAQALE
AVIARRETREPVSRILGHRGFWRFDLALGADTLDPRPDTETLVEAGLAVLEGCGGRILDLGTGSGCILLALLADRPGAIG
LGIDIAPGAVRVALRNARALGLERRALFAVGDWAAAVAGPFDLIVSNPPYIPSADIAALEPEVARFDPSRALDGGADGLD
PYRILAAQVPALLAPAGVLAVEFGQGQARDVAGLLEVGGLCPYEIKKDLSGEERCLLARRRAAGPLPPIHIDAKPSAPGN
GPTKA

Sequences:

>Translated_325_residues
MSDGDGGGEQGGGGPAEAEESALVLGRLLDRGAWRLKVAGVEKPRRDARLLAGHVLGLSPGAVLLADDRVVTPEEAQALE
AVIARRETREPVSRILGHRGFWRFDLALGADTLDPRPDTETLVEAGLAVLEGCGGRILDLGTGSGCILLALLADRPGAIG
LGIDIAPGAVRVALRNARALGLERRALFAVGDWAAAVAGPFDLIVSNPPYIPSADIAALEPEVARFDPSRALDGGADGLD
PYRILAAQVPALLAPAGVLAVEFGQGQARDVAGLLEVGGLCPYEIKKDLSGEERCLLARRRAAGPLPPIHIDAKPSAPGN
GPTKA
>Mature_324_residues
SDGDGGGEQGGGGPAEAEESALVLGRLLDRGAWRLKVAGVEKPRRDARLLAGHVLGLSPGAVLLADDRVVTPEEAQALEA
VIARRETREPVSRILGHRGFWRFDLALGADTLDPRPDTETLVEAGLAVLEGCGGRILDLGTGSGCILLALLADRPGAIGL
GIDIAPGAVRVALRNARALGLERRALFAVGDWAAAVAGPFDLIVSNPPYIPSADIAALEPEVARFDPSRALDGGADGLDP
YRILAAQVPALLAPAGVLAVEFGQGQARDVAGLLEVGGLCPYEIKKDLSGEERCLLARRRAAGPLPPIHIDAKPSAPGNG
PTKA

Specific function: Probable protein methyltransferase. May methylate a Gln residue in target proteins [H]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hemK family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=285, Percent_Identity=30.1754385964912, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1787463, Length=264, Percent_Identity=37.8787878787879, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87082085, Length=203, Percent_Identity=31.0344827586207, Blast_Score=82, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24582226, Length=258, Percent_Identity=29.8449612403101, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR019874
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 2.1.1.-

Molecular weight: Translated: 33544; Mature: 33413

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGDGGGEQGGGGPAEAEESALVLGRLLDRGAWRLKVAGVEKPRRDARLLAGHVLGLSP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHEECCC
GAVLLADDRVVTPEEAQALEAVIARRETREPVSRILGHRGFWRFDLALGADTLDPRPDTE
CEEEEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHH
TLVEAGLAVLEGCGGRILDLGTGSGCILLALLADRPGAIGLGIDIAPGAVRVALRNARAL
HHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCEEECEEECCCHHHHHHHHHHHH
GLERRALFAVGDWAAAVAGPFDLIVSNPPYIPSADIAALEPEVARFDPSRALDGGADGLD
CCCCCEEEEECCHHHHHCCCEEEEECCCCCCCCCCCHHCCCHHHHCCCCCCCCCCCCCCC
PYRILAAQVPALLAPAGVLAVEFGQGQARDVAGLLEVGGLCPYEIKKDLSGEERCLLARR
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHH
RAAGPLPPIHIDAKPSAPGNGPTKA
HCCCCCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SDGDGGGEQGGGGPAEAEESALVLGRLLDRGAWRLKVAGVEKPRRDARLLAGHVLGLSP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHEECCC
GAVLLADDRVVTPEEAQALEAVIARRETREPVSRILGHRGFWRFDLALGADTLDPRPDTE
CEEEEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHH
TLVEAGLAVLEGCGGRILDLGTGSGCILLALLADRPGAIGLGIDIAPGAVRVALRNARAL
HHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCEEECEEECCCHHHHHHHHHHHH
GLERRALFAVGDWAAAVAGPFDLIVSNPPYIPSADIAALEPEVARFDPSRALDGGADGLD
CCCCCEEEEECCHHHHHCCCEEEEECCCCCCCCCCCHHCCCHHHHCCCCCCCCCCCCCCC
PYRILAAQVPALLAPAGVLAVEFGQGQARDVAGLLEVGGLCPYEIKKDLSGEERCLLARR
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHH
RAAGPLPPIHIDAKPSAPGNGPTKA
HCCCCCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]