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The map label for this gene is purQ

Identifier: 83592048

GI number: 83592048

Start: 837695

End: 838387

Strand: Reverse

Name: purQ

Synonym: Rru_A0709

Alternate gene names: 83592048

Gene position: 838387-837695 (Counterclockwise)

Preceding gene: 83592049

Following gene: 83592047

Centisome position: 19.26

GC content: 68.54

Gene sequence:

>693_bases
ATGAACTCCGCGATCATCGTCTTCCCCGGCACCAACCGGGAGCGGGACATGGCCAAGGCGCTGACCCTAGTCGGCGGCAA
GGCCCCTCAGATGGTCTGGCACAGGGATAGCGCTCTGCCCGCCGGCCTCGATCTCGTCGTCCTGCCCGGCGGCTTTTCCT
ATGGGGATTACCTGCGCTCGGGCGCCATGGGCGCGCGCAGCCCCATCCTCGACGCCGTCCGCCGCTTCGCCGAGGCCGGT
GGTCACGTGCTGGGCGTGTGCAACGGCTTCCAGATCCTGACCGAGGCCGGGCTGCTGCCCGGCGCCCTGATGCGCAACCG
CGATCTGCGCTTCATCTGCCGCGATGTCCACCTGCGGGTGGAAACCATCGCCAGCCCCTATACCTCGGCCTATGGCCTTG
GCGAGGTCGCCCGGGTTCCCGTCGCCCATCACGATGGCAATTACTTCGCCGATGACGCCACCTTGGCCCAATTGGCCGAT
GAAGACCGCGTCGCCTTCCGCTATTGCGCGGCCGATGGCACGGTGGGCGAGGCCAGCACCCCCAATGGGTCGCGCGACGC
CATCGCCGGCATCCTGTCGGCCAACCGCCGGGTGCTCGGCATGATGCCCCACCCCGAAAACCTGGTCGAACCGGCGCTGG
GCGGCATCGGCGGCCGGGCGCTGTTTCAGTCCATCGTGGAGAGCCTGTCGTGA

Upstream 100 bases:

>100_bases
GCGTCGACGCCATGTGCCGCAAGCTGCTGGCCAATACGGTGATCGAAAACTACGCCATCGAGATCGCCTGACACCCCTCC
CCTCGCATTCGGAACTCGCC

Downstream 100 bases:

>100_bases
GCCAGTCTGCGAGCACTCCGGCGACGCCCATCACGGCGAAGATCGTCGCCGAGCACGGGTTGACCGAGGCCGAATACGCC
AAGGTCCTCGCCATCATGGG

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNSAIIVFPGTNRERDMAKALTLVGGKAPQMVWHRDSALPAGLDLVVLPGGFSYGDYLRSGAMGARSPILDAVRRFAEAG
GHVLGVCNGFQILTEAGLLPGALMRNRDLRFICRDVHLRVETIASPYTSAYGLGEVARVPVAHHDGNYFADDATLAQLAD
EDRVAFRYCAADGTVGEASTPNGSRDAIAGILSANRRVLGMMPHPENLVEPALGGIGGRALFQSIVESLS

Sequences:

>Translated_230_residues
MNSAIIVFPGTNRERDMAKALTLVGGKAPQMVWHRDSALPAGLDLVVLPGGFSYGDYLRSGAMGARSPILDAVRRFAEAG
GHVLGVCNGFQILTEAGLLPGALMRNRDLRFICRDVHLRVETIASPYTSAYGLGEVARVPVAHHDGNYFADDATLAQLAD
EDRVAFRYCAADGTVGEASTPNGSRDAIAGILSANRRVLGMMPHPENLVEPALGGIGGRALFQSIVESLS
>Mature_230_residues
MNSAIIVFPGTNRERDMAKALTLVGGKAPQMVWHRDSALPAGLDLVVLPGGFSYGDYLRSGAMGARSPILDAVRRFAEAG
GHVLGVCNGFQILTEAGLLPGALMRNRDLRFICRDVHLRVETIASPYTSAYGLGEVARVPVAHHDGNYFADDATLAQLAD
EDRVAFRYCAADGTVGEASTPNGSRDAIAGILSANRRVLGMMPHPENLVEPALGGIGGRALFQSIVESLS

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=179, Percent_Identity=36.3128491620112, Blast_Score=73, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582111, Length=187, Percent_Identity=32.620320855615, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582109, Length=187, Percent_Identity=32.620320855615, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17137292, Length=187, Percent_Identity=32.620320855615, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_RHORT (Q2RWI2)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_425800.1
- ProteinModelPortal:   Q2RWI2
- SMR:   Q2RWI2
- STRING:   Q2RWI2
- GeneID:   3834025
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A0709
- NMPDR:   fig|1085.1.peg.1636
- eggNOG:   COG0047
- HOGENOM:   HBG302712
- OMA:   FPGTNCD
- BioCyc:   RRUB269796:RRU_A0709-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF07685 GATase_3

EC number: =6.3.5.3

Molecular weight: Translated: 24374; Mature: 24374

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS51273 GATASE_TYPE_1

Important sites: ACT_SITE 87-87 ACT_SITE 204-204 ACT_SITE 206-206

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSAIIVFPGTNRERDMAKALTLVGGKAPQMVWHRDSALPAGLDLVVLPGGFSYGDYLRS
CCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCHHHHHHH
GAMGARSPILDAVRRFAEAGGHVLGVCNGFQILTEAGLLPGALMRNRDLRFICRDVHLRV
CCCCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCHHHHCCCCHHEEHHHHHHHH
ETIASPYTSAYGLGEVARVPVAHHDGNYFADDATLAQLADEDRVAFRYCAADGTVGEAST
HHHHCCCHHHCCCCHHHCCCEEECCCCEECCCHHHHHHCCCCCEEEEEECCCCCCCCCCC
PNGSRDAIAGILSANRRVLGMMPHPENLVEPALGGIGGRALFQSIVESLS
CCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNSAIIVFPGTNRERDMAKALTLVGGKAPQMVWHRDSALPAGLDLVVLPGGFSYGDYLRS
CCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCHHHHHHH
GAMGARSPILDAVRRFAEAGGHVLGVCNGFQILTEAGLLPGALMRNRDLRFICRDVHLRV
CCCCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCHHHHCCCCHHEEHHHHHHHH
ETIASPYTSAYGLGEVARVPVAHHDGNYFADDATLAQLADEDRVAFRYCAADGTVGEAST
HHHHCCCHHHCCCCHHHCCCEEECCCCEECCCHHHHHHCCCCCEEEEEECCCCCCCCCCC
PNGSRDAIAGILSANRRVLGMMPHPENLVEPALGGIGGRALFQSIVESLS
CCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA