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The map label for this gene is purL

Identifier: 83592047

GI number: 83592047

Start: 835476

End: 837698

Strand: Reverse

Name: purL

Synonym: Rru_A0708

Alternate gene names: 83592047

Gene position: 837698-835476 (Counterclockwise)

Preceding gene: 83592048

Following gene: 83592046

Centisome position: 19.24

GC content: 67.16

Gene sequence:

>2223_bases
GTGAGCCAGTCTGCGAGCACTCCGGCGACGCCCATCACGGCGAAGATCGTCGCCGAGCACGGGTTGACCGAGGCCGAATA
CGCCAAGGTCCTCGCCATCATGGGGCGCGAGCCCAATCTGGTCGAACTGGGCATCTTCTCGGTCATGTGGTCGGAGCATT
GCTCCTACAAGTCCTCGAAGAAGTGGCTCAAGACCCTGCCGACCACGGCGCCCTGGGTGATCCAGGGACCGGGCGAGAAC
GCCGGGGTCATCGACATCGGCGATGGCCTGACCGCCATCTTCAAGATGGAAAGCCATAACCACCCCAGCTACATCGAGCC
CTATCAGGGCGCGGCGACGGGCGTTGGCGGCATCTTGCGCGATGTCTTCACCATGGGCGCCCGGCCGGTGGCCAATCTCA
ACGCCTTGCGCTTTGGCGATCCCTCCGACCCGCGCACCCGCCACCTGATCTCGGGCGTCGTCGCCGGCATCGGCGGCTAT
GGCAATTGCGTCGGCGTGCCCACCGTTGGCGGCGAGGTCAATTTCCACGCCAGCTTCAACGGCAATAATCTGGTCAACGC
CATGACCGTCGGCGTCGCCCGCGCCGACCGCATCTTCTATTCGGCCGCCGCCGGCATCGGCAATTCGGTGGTCTATGTCG
GTTCGAAGACCGGCCGCGACGGCATCCACGGCGCCACCATGGCCTCGGCCGAGTTCTCCGAGGACTCCGAGGAAAAGCGC
CCCACCGTTCAGGTCGGCGACCCGTTCACCGAAAAGCTGCTGATCGAAGCCTGCCTGGAACTGATGAACACCGACGCCAT
CGTCGCCATTCAGGACATGGGGGCGGCCGGTCTGACCTCCTCATGCTTCGAGATGGCCTCGAAGGGCGGCATGGGCGTCG
ATCTGGCCCTTGACCGCGTGCCGATGCGCGAAGAGGGCATGACCCCTTACGAACTGATGCTGTCGGAAAGCCAGGAGCGC
ATGCTCATGGTGCTCAAGCCCGGCAAGGAGGACATGGCGCGCGCCCTGTTCGAGAAGTGGGAGCTTGATTTCGCCATCAT
CGGCACCCTGACCGACAGCGGCCGCATGGTGCTGACTTGGCATGGCGAGGTTGTCGGCGATCTGCCGATCGATCCGCTGG
CCGCCGCCAGCCCCGAATACGACCGGCCCTGGGAACCGACGCCGATGGCCGCCGCCGCCGATCTCAGCGGCGCCGAGGAC
ACGCCGTGGAGCGAGGCCCTGCTGCGCCTGATCGGCTGCCCCGATGTCGCCAGCCGGCGCTGGATCTGGGAGCAGTATGA
CCATCTGGTGATGGGCAATACCCTGCAGCGTCCCGGTGGCGACGCCGCGGTGATCCGCCTTGACGAGGCGCCGGGCAAGG
GTCTGGCGATGACCACCGATTGCACGCCGCGCTACGTCCACGCCGATCCGGTCGAAGGCGGCAAGCAGGCGGTGGCCGAG
GCTTGGCGCAATCTGACCGCCGTCGGCGCCCGGCCCTTGGCCATCACCGACAACATGAACTTCGGCAATCCCGAAAAGCC
GCGGATCATGGGCCAGTTCGTCGGCGCCTGCCAGGGGATCAGCGAGGCCTGTCTGGCCCTCGACTTCCCGGTGGTCTCGG
GCAATGTCTCGCTCTACAACGAGACCAACGGTCAGGCGATTTTACCGACCCCGACCATCGGCGGCGTCGGCGTGCTTGAT
AACGTCGAAGCCAGCGTCTCCATCGCCCTCAAGGCGGCCGGCGAGGCCATCCTGGTGGCCGGCGGCTTCCATGGCTCGAC
CGGGGCATGGCTTGGCCAGTCGCTGTTCCTGCGCGAAATCCTGGGCCGCGAAGAAGGCGCGCCGCCGCCCGTCGATCTGG
CGGCCGAGCGCAAGGTTGGCGATTTCGTCCGTGGGCTGATCCTTGGCGCGAGCGTCACCGCCTGCCACGATCTGTCCGAT
GGCGGCCTGCTGGTCGCCCTGGCCGAAATGGCCATGGCCGGCGACCTGGGGGCCGAGCTGACGCTGGAGGGCCATCCCGA
CAATGGCCGGCTGTTTGGCGAGGATCAGGGCCGCTATCTGCTGACGGTCGCCGAAGGCGACCGCGACGCGGTGGTCGCGG
CGGCCGAGGCCGCCGGCGTGCCGCTGCGGGTGGTCGGCACCACCGGCGGCGACGCCCTGGTGGTCAACGGCTTTGTCGGA
CCCAGCGTGGCAGCCTTGCGCAAGGTTCACGAGGAGTGGCTGCCCACCTATATGGCGGGTTAG

Upstream 100 bases:

>100_bases
GGGTGCTCGGCATGATGCCCCACCCCGAAAACCTGGTCGAACCGGCGCTGGGCGGCATCGGCGGCCGGGCGCTGTTTCAG
TCCATCGTGGAGAGCCTGTC

Downstream 100 bases:

>100_bases
ATCGCGACGCCAGCCGACAGACCTCTTTGAGAGCGGCGCGGGGAAAAGCCCTTTCCCCTTTCCCCTGCGCCGCTCTACTC
TTGTTTTTTTTCCCCTCCCC

Product: phosphoribosylformylglycinamidine synthase II

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II

Number of amino acids: Translated: 740; Mature: 739

Protein sequence:

>740_residues
MSQSASTPATPITAKIVAEHGLTEAEYAKVLAIMGREPNLVELGIFSVMWSEHCSYKSSKKWLKTLPTTAPWVIQGPGEN
AGVIDIGDGLTAIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPVANLNALRFGDPSDPRTRHLISGVVAGIGGY
GNCVGVPTVGGEVNFHASFNGNNLVNAMTVGVARADRIFYSAAAGIGNSVVYVGSKTGRDGIHGATMASAEFSEDSEEKR
PTVQVGDPFTEKLLIEACLELMNTDAIVAIQDMGAAGLTSSCFEMASKGGMGVDLALDRVPMREEGMTPYELMLSESQER
MLMVLKPGKEDMARALFEKWELDFAIIGTLTDSGRMVLTWHGEVVGDLPIDPLAAASPEYDRPWEPTPMAAAADLSGAED
TPWSEALLRLIGCPDVASRRWIWEQYDHLVMGNTLQRPGGDAAVIRLDEAPGKGLAMTTDCTPRYVHADPVEGGKQAVAE
AWRNLTAVGARPLAITDNMNFGNPEKPRIMGQFVGACQGISEACLALDFPVVSGNVSLYNETNGQAILPTPTIGGVGVLD
NVEASVSIALKAAGEAILVAGGFHGSTGAWLGQSLFLREILGREEGAPPPVDLAAERKVGDFVRGLILGASVTACHDLSD
GGLLVALAEMAMAGDLGAELTLEGHPDNGRLFGEDQGRYLLTVAEGDRDAVVAAAEAAGVPLRVVGTTGGDALVVNGFVG
PSVAALRKVHEEWLPTYMAG

Sequences:

>Translated_740_residues
MSQSASTPATPITAKIVAEHGLTEAEYAKVLAIMGREPNLVELGIFSVMWSEHCSYKSSKKWLKTLPTTAPWVIQGPGEN
AGVIDIGDGLTAIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPVANLNALRFGDPSDPRTRHLISGVVAGIGGY
GNCVGVPTVGGEVNFHASFNGNNLVNAMTVGVARADRIFYSAAAGIGNSVVYVGSKTGRDGIHGATMASAEFSEDSEEKR
PTVQVGDPFTEKLLIEACLELMNTDAIVAIQDMGAAGLTSSCFEMASKGGMGVDLALDRVPMREEGMTPYELMLSESQER
MLMVLKPGKEDMARALFEKWELDFAIIGTLTDSGRMVLTWHGEVVGDLPIDPLAAASPEYDRPWEPTPMAAAADLSGAED
TPWSEALLRLIGCPDVASRRWIWEQYDHLVMGNTLQRPGGDAAVIRLDEAPGKGLAMTTDCTPRYVHADPVEGGKQAVAE
AWRNLTAVGARPLAITDNMNFGNPEKPRIMGQFVGACQGISEACLALDFPVVSGNVSLYNETNGQAILPTPTIGGVGVLD
NVEASVSIALKAAGEAILVAGGFHGSTGAWLGQSLFLREILGREEGAPPPVDLAAERKVGDFVRGLILGASVTACHDLSD
GGLLVALAEMAMAGDLGAELTLEGHPDNGRLFGEDQGRYLLTVAEGDRDAVVAAAEAAGVPLRVVGTTGGDALVVNGFVG
PSVAALRKVHEEWLPTYMAG
>Mature_739_residues
SQSASTPATPITAKIVAEHGLTEAEYAKVLAIMGREPNLVELGIFSVMWSEHCSYKSSKKWLKTLPTTAPWVIQGPGENA
GVIDIGDGLTAIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPVANLNALRFGDPSDPRTRHLISGVVAGIGGYG
NCVGVPTVGGEVNFHASFNGNNLVNAMTVGVARADRIFYSAAAGIGNSVVYVGSKTGRDGIHGATMASAEFSEDSEEKRP
TVQVGDPFTEKLLIEACLELMNTDAIVAIQDMGAAGLTSSCFEMASKGGMGVDLALDRVPMREEGMTPYELMLSESQERM
LMVLKPGKEDMARALFEKWELDFAIIGTLTDSGRMVLTWHGEVVGDLPIDPLAAASPEYDRPWEPTPMAAAADLSGAEDT
PWSEALLRLIGCPDVASRRWIWEQYDHLVMGNTLQRPGGDAAVIRLDEAPGKGLAMTTDCTPRYVHADPVEGGKQAVAEA
WRNLTAVGARPLAITDNMNFGNPEKPRIMGQFVGACQGISEACLALDFPVVSGNVSLYNETNGQAILPTPTIGGVGVLDN
VEASVSIALKAAGEAILVAGGFHGSTGAWLGQSLFLREILGREEGAPPPVDLAAERKVGDFVRGLILGASVTACHDLSDG
GLLVALAEMAMAGDLGAELTLEGHPDNGRLFGEDQGRYLLTVAEGDRDAVVAAAEAAGVPLRVVGTTGGDALVVNGFVGP
SVAALRKVHEEWLPTYMAG

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family

Homologues:

Organism=Homo sapiens, GI31657129, Length=700, Percent_Identity=27.7142857142857, Blast_Score=111, Evalue=2e-24,
Organism=Escherichia coli, GI48994899, Length=786, Percent_Identity=26.7175572519084, Blast_Score=153, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17553022, Length=735, Percent_Identity=24.2176870748299, Blast_Score=102, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6321498, Length=777, Percent_Identity=23.4234234234234, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24582111, Length=740, Percent_Identity=25.6756756756757, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24582109, Length=740, Percent_Identity=25.6756756756757, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17137292, Length=740, Percent_Identity=25.6756756756757, Blast_Score=118, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURL_RHORT (Q2RWI3)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_425799.1
- ProteinModelPortal:   Q2RWI3
- SMR:   Q2RWI3
- STRING:   Q2RWI3
- GeneID:   3833945
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A0708
- NMPDR:   fig|1085.1.peg.1637
- eggNOG:   COG0046
- HOGENOM:   HBG311214
- OMA:   YGNSFGV
- PhylomeDB:   Q2RWI3
- BioCyc:   RRUB269796:RRU_A0708-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00420
- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188
- TIGRFAMs:   TIGR01736

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C; SSF56042 AIR_synth_C; SSF55326 PurM_N-like

EC number: =6.3.5.3

Molecular weight: Translated: 77893; Mature: 77762

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSASTPATPITAKIVAEHGLTEAEYAKVLAIMGREPNLVELGIFSVMWSEHCSYKSSK
CCCCCCCCCCCCEEEHHHHCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCHHH
KWLKTLPTTAPWVIQGPGENAGVIDIGDGLTAIFKMESHNHPSYIEPYQGAATGVGGILR
HHHHHCCCCCCEEEECCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
DVFTMGARPVANLNALRFGDPSDPRTRHLISGVVAGIGGYGNCVGVPTVGGEVNFHASFN
HHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEECC
GNNLVNAMTVGVARADRIFYSAAAGIGNSVVYVGSKTGRDGIHGATMASAEFSEDSEEKR
CCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCHHHCC
PTVQVGDPFTEKLLIEACLELMNTDAIVAIQDMGAAGLTSSCFEMASKGGMGVDLALDRV
CEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCC
PMREEGMTPYELMLSESQERMLMVLKPGKEDMARALFEKWELDFAIIGTLTDSGRMVLTW
CCHHCCCCHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEE
HGEVVGDLPIDPLAAASPEYDRPWEPTPMAAAADLSGAEDTPWSEALLRLIGCPDVASRR
CCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHCCCCHHHCC
WIWEQYDHLVMGNTLQRPGGDAAVIRLDEAPGKGLAMTTDCTPRYVHADPVEGGKQAVAE
HHHHHHCCEEECCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCEEECCCCCCHHHHHHH
AWRNLTAVGARPLAITDNMNFGNPEKPRIMGQFVGACQGISEACLALDFPVVSGNVSLYN
HHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCHHHHHHEEECEEEECCEEEEE
ETNGQAILPTPTIGGVGVLDNVEASVSIALKAAGEAILVAGGFHGSTGAWLGQSLFLREI
CCCCCEEECCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHH
LGREEGAPPPVDLAAERKVGDFVRGLILGASVTACHDLSDGGLLVALAEMAMAGDLGAEL
HCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHEECCCCCCCHHHHHHHHHHHCCCCCEE
TLEGHPDNGRLFGEDQGRYLLTVAEGDRDAVVAAAEAAGVPLRVVGTTGGDALVVNGFVG
EEECCCCCCEEEECCCCCEEEEEECCCCCEEEEEHHHCCCCEEEEECCCCCEEEEECCCC
PSVAALRKVHEEWLPTYMAG
CHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQSASTPATPITAKIVAEHGLTEAEYAKVLAIMGREPNLVELGIFSVMWSEHCSYKSSK
CCCCCCCCCCCEEEHHHHCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCHHH
KWLKTLPTTAPWVIQGPGENAGVIDIGDGLTAIFKMESHNHPSYIEPYQGAATGVGGILR
HHHHHCCCCCCEEEECCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
DVFTMGARPVANLNALRFGDPSDPRTRHLISGVVAGIGGYGNCVGVPTVGGEVNFHASFN
HHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEECC
GNNLVNAMTVGVARADRIFYSAAAGIGNSVVYVGSKTGRDGIHGATMASAEFSEDSEEKR
CCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCHHHCC
PTVQVGDPFTEKLLIEACLELMNTDAIVAIQDMGAAGLTSSCFEMASKGGMGVDLALDRV
CEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCC
PMREEGMTPYELMLSESQERMLMVLKPGKEDMARALFEKWELDFAIIGTLTDSGRMVLTW
CCHHCCCCHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEE
HGEVVGDLPIDPLAAASPEYDRPWEPTPMAAAADLSGAEDTPWSEALLRLIGCPDVASRR
CCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHCCCCHHHCC
WIWEQYDHLVMGNTLQRPGGDAAVIRLDEAPGKGLAMTTDCTPRYVHADPVEGGKQAVAE
HHHHHHCCEEECCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCEEECCCCCCHHHHHHH
AWRNLTAVGARPLAITDNMNFGNPEKPRIMGQFVGACQGISEACLALDFPVVSGNVSLYN
HHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCHHHHHHEEECEEEECCEEEEE
ETNGQAILPTPTIGGVGVLDNVEASVSIALKAAGEAILVAGGFHGSTGAWLGQSLFLREI
CCCCCEEECCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHH
LGREEGAPPPVDLAAERKVGDFVRGLILGASVTACHDLSDGGLLVALAEMAMAGDLGAEL
HCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHEECCCCCCCHHHHHHHHHHHCCCCCEE
TLEGHPDNGRLFGEDQGRYLLTVAEGDRDAVVAAAEAAGVPLRVVGTTGGDALVVNGFVG
EEECCCCCCEEEECCCCCEEEEEECCCCCEEEEEHHHCCCCEEEEECCCCCEEEEECCCC
PSVAALRKVHEEWLPTYMAG
CHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA