Click here to switch to the map view.

The map label for this gene is cobT [H]

Identifier: 83592006

GI number: 83592006

Start: 790447

End: 791454

Strand: Reverse

Name: cobT [H]

Synonym: Rru_A0667

Alternate gene names: 83592006

Gene position: 791454-790447 (Counterclockwise)

Preceding gene: 83592011

Following gene: 83592005

Centisome position: 18.18

GC content: 70.63

Gene sequence:

>1008_bases
ATGATCCAGACCCTTGACGACCTGCGCGTCCTTCTCGGCACCCTTCCCGGCCCCGACACCGTCTGTCGCGATATCGCCCT
GGCCCGCGAGCCGCAGCTGACCAAGCCCCGGGGCGCGCTGGGACGGATCGAACAGCTCGCCGCCTTCCTGAGCGCTTGGC
AAGGACGCCATCCGCCGGCCATGCAGGCGCCCGTCGCCCATGTCTTCGCCGGCAATCACGGAGTCGCCGCCCTGGGCGTT
TCGGCCTTCCCGCCCGAGGTCACGCTGCAGATGGTCGCCAATTACCGCAAGGGCGGCGCCGCCATCAACCAGCTGTGCCG
GGCCTTCGGCGTTCGCCTGGGGGTGACCGAGATCGACCTTGACCATCCGACCAAGCCCTTCAACCAGGAACCGGCGATGG
ACGAGGCCGAGGTGGTGGCCGCGCTTAATATCGGCCTGGGGATGGATCTGGCCGGCGCCGATTGCCTGTGCCTGGGCGAG
ATGGGCATCGCCAACACCACCGCCGCCGCCGCCATCGCCCTCGCCCTCTATGGCGGCACGGCCGAGGATTGGACCGGTCC
GGGCAGCGGCGTCAGCGGTTCGGCGCTTGATACCAAGATCAAGGTGGTGGCCGAAGGGGCGGCCCGTCACGCCAAGGCCG
GCGACGGCCTGGAGATCCTGCGCCGCCTGGGCGGGCGCGAATTGGCCGCCATCGCCGGCGGCATCATCGCCGCCCGCCTC
GCCCGGGTGCCGGTGGTCCTGGATGGTTTCATCGTGTGTTCGGCCGCCGCCTGCCTGAAGGCCGTCGCCGCCGACGCCCT
TGACCATTGCGTCCTTGGCCACGTCTCGCGCGAACCCGGCCACCGCCGGCTGGTCAAGGCCCTCGGCCTCGACCCGCTGC
TTGACATCGGCATGGCCCTGGGCGAGGCGACGGGCGCGGTCACAGCGGTGCCGCTGCTCAAGGCCGCCTGCCAGTGCCAT
ATGGGCATGTCCACCTTCGCCGAGGCCGGGGTCACCGACCACGACTAG

Upstream 100 bases:

>100_bases
AAAGAACGGGCCGCTTGCCCCGTCCGGGGCTCTTCCCATAGCGGATCGTACCGCGTCTTGCCAGTCCTCACCCGCCTTAT
CAGGAAGAAACCCCTTGCCA

Downstream 100 bases:

>100_bases
ACCTCACCGCGTCAAAGGAGGCCCCTTTGACGCGGCAGCTTTTGCGCGACGGGACCAGAGGAACGCGGCGATGGCGGGAA
AGGCCGCTATCGCCCTTGCC

Product: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MIQTLDDLRVLLGTLPGPDTVCRDIALAREPQLTKPRGALGRIEQLAAFLSAWQGRHPPAMQAPVAHVFAGNHGVAALGV
SAFPPEVTLQMVANYRKGGAAINQLCRAFGVRLGVTEIDLDHPTKPFNQEPAMDEAEVVAALNIGLGMDLAGADCLCLGE
MGIANTTAAAAIALALYGGTAEDWTGPGSGVSGSALDTKIKVVAEGAARHAKAGDGLEILRRLGGRELAAIAGGIIAARL
ARVPVVLDGFIVCSAAACLKAVAADALDHCVLGHVSREPGHRRLVKALGLDPLLDIGMALGEATGAVTAVPLLKAACQCH
MGMSTFAEAGVTDHD

Sequences:

>Translated_335_residues
MIQTLDDLRVLLGTLPGPDTVCRDIALAREPQLTKPRGALGRIEQLAAFLSAWQGRHPPAMQAPVAHVFAGNHGVAALGV
SAFPPEVTLQMVANYRKGGAAINQLCRAFGVRLGVTEIDLDHPTKPFNQEPAMDEAEVVAALNIGLGMDLAGADCLCLGE
MGIANTTAAAAIALALYGGTAEDWTGPGSGVSGSALDTKIKVVAEGAARHAKAGDGLEILRRLGGRELAAIAGGIIAARL
ARVPVVLDGFIVCSAAACLKAVAADALDHCVLGHVSREPGHRRLVKALGLDPLLDIGMALGEATGAVTAVPLLKAACQCH
MGMSTFAEAGVTDHD
>Mature_335_residues
MIQTLDDLRVLLGTLPGPDTVCRDIALAREPQLTKPRGALGRIEQLAAFLSAWQGRHPPAMQAPVAHVFAGNHGVAALGV
SAFPPEVTLQMVANYRKGGAAINQLCRAFGVRLGVTEIDLDHPTKPFNQEPAMDEAEVVAALNIGLGMDLAGADCLCLGE
MGIANTTAAAAIALALYGGTAEDWTGPGSGVSGSALDTKIKVVAEGAARHAKAGDGLEILRRLGGRELAAIAGGIIAARL
ARVPVVLDGFIVCSAAACLKAVAADALDHCVLGHVSREPGHRRLVKALGLDPLLDIGMALGEATGAVTAVPLLKAACQCH
MGMSTFAEAGVTDHD

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=350, Percent_Identity=30.8571428571429, Blast_Score=124, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 34339; Mature: 34339

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00591 GLYCOSYL_HYDROL_F10 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQTLDDLRVLLGTLPGPDTVCRDIALAREPQLTKPRGALGRIEQLAAFLSAWQGRHPPA
CCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
MQAPVAHVFAGNHGVAALGVSAFPPEVTLQMVANYRKGGAAINQLCRAFGVRLGVTEIDL
HHCCHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECC
DHPTKPFNQEPAMDEAEVVAALNIGLGMDLAGADCLCLGEMGIANTTAAAAIALALYGGT
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCC
AEDWTGPGSGVSGSALDTKIKVVAEGAARHAKAGDGLEILRRLGGRELAAIAGGIIAARL
CCCCCCCCCCCCCCHHHHHHHEEEHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHH
ARVPVVLDGFIVCSAAACLKAVAADALDHCVLGHVSREPGHRRLVKALGLDPLLDIGMAL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHH
GEATGAVTAVPLLKAACQCHMGMSTFAEAGVTDHD
HHHCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCC
>Mature Secondary Structure
MIQTLDDLRVLLGTLPGPDTVCRDIALAREPQLTKPRGALGRIEQLAAFLSAWQGRHPPA
CCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
MQAPVAHVFAGNHGVAALGVSAFPPEVTLQMVANYRKGGAAINQLCRAFGVRLGVTEIDL
HHCCHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECC
DHPTKPFNQEPAMDEAEVVAALNIGLGMDLAGADCLCLGEMGIANTTAAAAIALALYGGT
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCC
AEDWTGPGSGVSGSALDTKIKVVAEGAARHAKAGDGLEILRRLGGRELAAIAGGIIAARL
CCCCCCCCCCCCCCHHHHHHHEEEHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHH
ARVPVVLDGFIVCSAAACLKAVAADALDHCVLGHVSREPGHRRLVKALGLDPLLDIGMAL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHH
GEATGAVTAVPLLKAACQCHMGMSTFAEAGVTDHD
HHHCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA