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The map label for this gene is ykoW [H]

Identifier: 83591998

GI number: 83591998

Start: 781071

End: 783371

Strand: Reverse

Name: ykoW [H]

Synonym: Rru_A0659

Alternate gene names: 83591998

Gene position: 783371-781071 (Counterclockwise)

Preceding gene: 83591999

Following gene: 83591996

Centisome position: 18.0

GC content: 64.36

Gene sequence:

>2301_bases
ATGACACCGAATGAGGATCTGATAGAGATCTTCGAAGACGAGGAAATTTCCCCCTCCTTGACGGCCAAGACATGGCCGAT
CCTCATCGTCGATGATGACCAGGATGTCCATGATGTCTCGCGGCTCGCTCTGCGTGGCGTGCGCCTGCTCGATTACGACC
TGGAAACGCTTCACGCCTATAGCGCCGCGCAAGCCCGCGCTATCTTGTCCAGCCGCTCCGACATCGCCGTCGCCCTGCTC
GATGTGGTGATGGAGCGCGAGGACGCCGGCCTCGACCTTGTCCGCTGGATCCGCTCCGACCCGGCGCGGGATCTGCTGCG
CATCGTCTTGCGCACCGGCCAGCCCGGTTACGCCCCCGAGGCCACGGTCATCCAGGACTATGACATCAACGATTACCGCA
CCAAATCCGAACTCAATCGCGGGCGGTTGATCAGCATCCTGACCACCGCCTTGCGCTCCTATCGCCAGATGGCGGTGATC
GCCGCCAGCCGCGACGGCCTGGACAAGATCGTGCGCGCCTCGGCCGACCTGCTGGCCTCGCCGTCGATGGCGATCTTCGC
CGAAGGGGTGCTGACCCAGCTTGCCGGACTGCTGGGCACCGAACGCTCGGGGATCGTTCTCGCCCGCCGGAATCGCCGTC
CCGGAGCCACCGCGTCGATGGCGATGACCGGCGACGAGGGGTTCGTCCTTGCCGCCGCCGGACCGCTGAGCGCCGATATC
GGCCGGCCGCTGTCCGATATCGGCGACCACCAGACCGCCGAAATCCTGCGCCGCACCCTGGAAAGCCGACGCTCGTCCTT
CGATCACGGCTCCATGGCGCTCTATATCGCCACGCCCAACGGCGATTCCCTGGCCGTGCTGATGGAGGTGGCGAAAACGC
TGGGCGATACGGACCGCAAGCTGGTCGAGGTGTTCTGCGTCAACATGGCCGCCGGCTTCGACACCATCAGCCTGTTCGAG
CAGATCAGCCTTCAGGCGTTCCACGACGAGGCGACGGGGCTGCCCAATCTGGCGGCCTGCCAGAGCCTGATCGACCAATA
CCTGCAGCGGCGCCAGCCGGTGGCCGTGACCTTTTTTTCCCTTGAGGGCTTTTCGGCGATCAGCGATACCCTGGGGCGGG
TGATCGGCGATCGCATGATCGGCCTGCTGGCCAATGCCTTCCGCCACCGCTTGCAAGAGCGCGGCGAGGTGTTCCGCGTC
GGACAGGAAACCCTGGCCACGGTGATCGGCGGCCCCGTCGATCAGGTTGGACCTTTGGCCGACCAACTGGCGGGCGATTT
CCGCGCGGGTTTGCCGCTTGACTCGATGACCCTGCCGGTCTCGTTCTCCCATGGCACCTCGGTCTCGACCTCCGAACACG
ACACCGCGCAAATCCTGGTCCAGCGCGCCGGCATCGCCATGCAAAAGGCCCGCAACATCAAGCGCGGCGGCGGGCTGACC
TATGCGGTGGCGATGGAGGAGGAAATCCGCGCCCATATCGGCGTCATCTCAAAGCTGGGCGCGGGCGTCGTCTCGGAGGC
CTTCGTCGCCGTCTTCCAACCCAAGATCCGCTTGGCCGATCGCAGTTGCCACGGCGGCGAGGCCCTGGTCCGCTGGCGCG
ATGGCGATGGCACGATGATCGCGCCGTCGCTGTTCATCCCGGCGGCGGAAACCTCGGGCCATATCGTCGATATCGGCTAT
TCGGTCTTCCGCCAAAGCTGCGCCATGATCCGCTCGCTGAAGGTTTCGCAAGATGACGCGCGGATCGCCGTCAATCTGTC
GGTCCGCCAGATGCGCGAACCCGATCTGATCGACAAGCTGGTTTCCATCGCCGCCGAGGAAGGCGTGGCGACGACCCGGC
TCAAACTGGAAATCACCGAAAGCATCGTCATCGACGACCTAACGCATACCGTATCGCTTCTCAAAGCCCTAAAGGATAAG
GGATTTCTGCTGGCCCTGGATGATTTCGGCACGGGCTATTCCTCGCTCAGCTATCTGCGCAGCCTGCCCATCGACACCTT
GAAGATCGACCGCAGCTTCGTCTCGGGCCTCGCCGAACAGGCCGATATGCGCAAGATCGTCGGCTTGATCATCGGCCTTG
GCCATGAGCTTGGCTTCGACATCACCGCCGAGGGCGTGGAAACCGAGGAGGAGGCGCGGATCGTCACCGAAATGGGCTGT
TTCACCGCCCAGGGCTATTTGTTTTCCAAGCCCTTGAGCGCCGAGGATTTCCTGGTCTTCGCCCGCACCCACGCCGGGGC
CCGTCAAACCTCGGGCGGGTCGCTCTCGGCGGAGGGCTGTATCAGGGCCCGGGACGCCTGA

Upstream 100 bases:

>100_bases
TCGAGGGCGAGGGAACCCGCTTTACCCTCACCCTGCCCCGCGTCGCCCCCGCCGAAAAGCCCGTCGAGCAGCCCGTCCGG
CCCAAGGAGGCCCTAACGCC

Downstream 100 bases:

>100_bases
CCGACAACCGCGCGCGTCAGATCGGCAAGCTGATCGGCGGCAAGGCGGTTCACCTGCCAGAACAGCGGACTATCAAGCGT
CCGCCCGGGCAGGATTTCGA

Product: response regulator receiver modulated diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 766; Mature: 765

Protein sequence:

>766_residues
MTPNEDLIEIFEDEEISPSLTAKTWPILIVDDDQDVHDVSRLALRGVRLLDYDLETLHAYSAAQARAILSSRSDIAVALL
DVVMEREDAGLDLVRWIRSDPARDLLRIVLRTGQPGYAPEATVIQDYDINDYRTKSELNRGRLISILTTALRSYRQMAVI
AASRDGLDKIVRASADLLASPSMAIFAEGVLTQLAGLLGTERSGIVLARRNRRPGATASMAMTGDEGFVLAAAGPLSADI
GRPLSDIGDHQTAEILRRTLESRRSSFDHGSMALYIATPNGDSLAVLMEVAKTLGDTDRKLVEVFCVNMAAGFDTISLFE
QISLQAFHDEATGLPNLAACQSLIDQYLQRRQPVAVTFFSLEGFSAISDTLGRVIGDRMIGLLANAFRHRLQERGEVFRV
GQETLATVIGGPVDQVGPLADQLAGDFRAGLPLDSMTLPVSFSHGTSVSTSEHDTAQILVQRAGIAMQKARNIKRGGGLT
YAVAMEEEIRAHIGVISKLGAGVVSEAFVAVFQPKIRLADRSCHGGEALVRWRDGDGTMIAPSLFIPAAETSGHIVDIGY
SVFRQSCAMIRSLKVSQDDARIAVNLSVRQMREPDLIDKLVSIAAEEGVATTRLKLEITESIVIDDLTHTVSLLKALKDK
GFLLALDDFGTGYSSLSYLRSLPIDTLKIDRSFVSGLAEQADMRKIVGLIIGLGHELGFDITAEGVETEEEARIVTEMGC
FTAQGYLFSKPLSAEDFLVFARTHAGARQTSGGSLSAEGCIRARDA

Sequences:

>Translated_766_residues
MTPNEDLIEIFEDEEISPSLTAKTWPILIVDDDQDVHDVSRLALRGVRLLDYDLETLHAYSAAQARAILSSRSDIAVALL
DVVMEREDAGLDLVRWIRSDPARDLLRIVLRTGQPGYAPEATVIQDYDINDYRTKSELNRGRLISILTTALRSYRQMAVI
AASRDGLDKIVRASADLLASPSMAIFAEGVLTQLAGLLGTERSGIVLARRNRRPGATASMAMTGDEGFVLAAAGPLSADI
GRPLSDIGDHQTAEILRRTLESRRSSFDHGSMALYIATPNGDSLAVLMEVAKTLGDTDRKLVEVFCVNMAAGFDTISLFE
QISLQAFHDEATGLPNLAACQSLIDQYLQRRQPVAVTFFSLEGFSAISDTLGRVIGDRMIGLLANAFRHRLQERGEVFRV
GQETLATVIGGPVDQVGPLADQLAGDFRAGLPLDSMTLPVSFSHGTSVSTSEHDTAQILVQRAGIAMQKARNIKRGGGLT
YAVAMEEEIRAHIGVISKLGAGVVSEAFVAVFQPKIRLADRSCHGGEALVRWRDGDGTMIAPSLFIPAAETSGHIVDIGY
SVFRQSCAMIRSLKVSQDDARIAVNLSVRQMREPDLIDKLVSIAAEEGVATTRLKLEITESIVIDDLTHTVSLLKALKDK
GFLLALDDFGTGYSSLSYLRSLPIDTLKIDRSFVSGLAEQADMRKIVGLIIGLGHELGFDITAEGVETEEEARIVTEMGC
FTAQGYLFSKPLSAEDFLVFARTHAGARQTSGGSLSAEGCIRARDA
>Mature_765_residues
TPNEDLIEIFEDEEISPSLTAKTWPILIVDDDQDVHDVSRLALRGVRLLDYDLETLHAYSAAQARAILSSRSDIAVALLD
VVMEREDAGLDLVRWIRSDPARDLLRIVLRTGQPGYAPEATVIQDYDINDYRTKSELNRGRLISILTTALRSYRQMAVIA
ASRDGLDKIVRASADLLASPSMAIFAEGVLTQLAGLLGTERSGIVLARRNRRPGATASMAMTGDEGFVLAAAGPLSADIG
RPLSDIGDHQTAEILRRTLESRRSSFDHGSMALYIATPNGDSLAVLMEVAKTLGDTDRKLVEVFCVNMAAGFDTISLFEQ
ISLQAFHDEATGLPNLAACQSLIDQYLQRRQPVAVTFFSLEGFSAISDTLGRVIGDRMIGLLANAFRHRLQERGEVFRVG
QETLATVIGGPVDQVGPLADQLAGDFRAGLPLDSMTLPVSFSHGTSVSTSEHDTAQILVQRAGIAMQKARNIKRGGGLTY
AVAMEEEIRAHIGVISKLGAGVVSEAFVAVFQPKIRLADRSCHGGEALVRWRDGDGTMIAPSLFIPAAETSGHIVDIGYS
VFRQSCAMIRSLKVSQDDARIAVNLSVRQMREPDLIDKLVSIAAEEGVATTRLKLEITESIVIDDLTHTVSLLKALKDKG
FLLALDDFGTGYSSLSYLRSLPIDTLKIDRSFVSGLAEQADMRKIVGLIIGLGHELGFDITAEGVETEEEARIVTEMGCF
TAQGYLFSKPLSAEDFLVFARTHAGARQTSGGSLSAEGCIRARDA

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87081921, Length=411, Percent_Identity=29.1970802919708, Blast_Score=183, Evalue=5e-47,
Organism=Escherichia coli, GI1787541, Length=423, Percent_Identity=29.0780141843972, Blast_Score=173, Evalue=4e-44,
Organism=Escherichia coli, GI226510982, Length=425, Percent_Identity=27.0588235294118, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1790496, Length=241, Percent_Identity=32.7800829875519, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1787055, Length=416, Percent_Identity=25.2403846153846, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87081845, Length=231, Percent_Identity=33.7662337662338, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87081743, Length=233, Percent_Identity=32.618025751073, Blast_Score=129, Evalue=1e-30,
Organism=Escherichia coli, GI87081980, Length=240, Percent_Identity=32.0833333333333, Blast_Score=127, Evalue=4e-30,
Organism=Escherichia coli, GI1786507, Length=248, Percent_Identity=31.0483870967742, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI1788502, Length=245, Percent_Identity=30.6122448979592, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788849, Length=275, Percent_Identity=28, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082096, Length=201, Percent_Identity=24.8756218905473, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787410, Length=153, Percent_Identity=28.7581699346405, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 82934; Mature: 82802

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPNEDLIEIFEDEEISPSLTAKTWPILIVDDDQDVHDVSRLALRGVRLLDYDLETLHAY
CCCCHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHEECCHHHHHHH
SAAQARAILSSRSDIAVALLDVVMEREDAGLDLVRWIRSDPARDLLRIVLRTGQPGYAPE
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
ATVIQDYDINDYRTKSELNRGRLISILTTALRSYRQMAVIAASRDGLDKIVRASADLLAS
CCEEEECCCCCHHCHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCC
PSMAIFAEGVLTQLAGLLGTERSGIVLARRNRRPGATASMAMTGDEGFVLAAAGPLSADI
CCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCCEEEEECCCCCHHH
GRPLSDIGDHQTAEILRRTLESRRSSFDHGSMALYIATPNGDSLAVLMEVAKTLGDTDRK
CCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCHHH
LVEVFCVNMAAGFDTISLFEQISLQAFHDEATGLPNLAACQSLIDQYLQRRQPVAVTFFS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEE
LEGFSAISDTLGRVIGDRMIGLLANAFRHRLQERGEVFRVGQETLATVIGGPVDQVGPLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCHHHHHHHH
DQLAGDFRAGLPLDSMTLPVSFSHGTSVSTSEHDTAQILVQRAGIAMQKARNIKRGGGLT
HHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEE
YAVAMEEEIRAHIGVISKLGAGVVSEAFVAVFQPKIRLADRSCHGGEALVRWRDGDGTMI
EEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEECCCCCCCCCEEEEEECCCCCEE
APSLFIPAAETSGHIVDIGYSVFRQSCAMIRSLKVSQDDARIAVNLSVRQMREPDLIDKL
CCEEEEECCCCCCCEEECCHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCCCHHHHHH
VSIAAEEGVATTRLKLEITESIVIDDLTHTVSLLKALKDKGFLLALDDFGTGYSSLSYLR
HHHHHHCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
SLPIDTLKIDRSFVSGLAEQADMRKIVGLIIGLGHELGFDITAEGVETEEEARIVTEMGC
HCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCEEECCCCCHHHHHHHHHHCC
FTAQGYLFSKPLSAEDFLVFARTHAGARQTSGGSLSAEGCIRARDA
CEECCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TPNEDLIEIFEDEEISPSLTAKTWPILIVDDDQDVHDVSRLALRGVRLLDYDLETLHAY
CCCHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHEECCHHHHHHH
SAAQARAILSSRSDIAVALLDVVMEREDAGLDLVRWIRSDPARDLLRIVLRTGQPGYAPE
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
ATVIQDYDINDYRTKSELNRGRLISILTTALRSYRQMAVIAASRDGLDKIVRASADLLAS
CCEEEECCCCCHHCHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCC
PSMAIFAEGVLTQLAGLLGTERSGIVLARRNRRPGATASMAMTGDEGFVLAAAGPLSADI
CCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCCEEEEECCCCCHHH
GRPLSDIGDHQTAEILRRTLESRRSSFDHGSMALYIATPNGDSLAVLMEVAKTLGDTDRK
CCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCHHH
LVEVFCVNMAAGFDTISLFEQISLQAFHDEATGLPNLAACQSLIDQYLQRRQPVAVTFFS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEE
LEGFSAISDTLGRVIGDRMIGLLANAFRHRLQERGEVFRVGQETLATVIGGPVDQVGPLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCHHHHHHHH
DQLAGDFRAGLPLDSMTLPVSFSHGTSVSTSEHDTAQILVQRAGIAMQKARNIKRGGGLT
HHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEE
YAVAMEEEIRAHIGVISKLGAGVVSEAFVAVFQPKIRLADRSCHGGEALVRWRDGDGTMI
EEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEECCCCCCCCCEEEEEECCCCCEE
APSLFIPAAETSGHIVDIGYSVFRQSCAMIRSLKVSQDDARIAVNLSVRQMREPDLIDKL
CCEEEEECCCCCCCEEECCHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCCCHHHHHH
VSIAAEEGVATTRLKLEITESIVIDDLTHTVSLLKALKDKGFLLALDDFGTGYSSLSYLR
HHHHHHCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
SLPIDTLKIDRSFVSGLAEQADMRKIVGLIIGLGHELGFDITAEGVETEEEARIVTEMGC
HCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCEEECCCCCHHHHHHHHHHCC
FTAQGYLFSKPLSAEDFLVFARTHAGARQTSGGSLSAEGCIRARDA
CEECCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]