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The map label for this gene is putA [H]

Identifier: 83591995

GI number: 83591995

Start: 775762

End: 779472

Strand: Direct

Name: putA [H]

Synonym: Rru_A0656

Alternate gene names: 83591995

Gene position: 775762-779472 (Clockwise)

Preceding gene: 83591992

Following gene: 83591997

Centisome position: 17.82

GC content: 69.12

Gene sequence:

>3711_bases
ATGTCCGATCTAGCCAGCCTGCGTTTGTCTTTGCGTCGTGAACCTTTGCGGGACGAGGCGGCGGTCGTCGCCGACCGTCT
CGCCGCCCTGCCGCTCGATGCCGACCGCCGTCAGGCGGTGTCCGAGGCCGGGCGGGCCCTGGTCGAACGGATGCGGGCCT
CGGGCGAGGTCACGATGATGGACAACATGCTGGCCGAATACGGCCTGTCCACCGACGAGGGCGTCGCCCTGATGTGTCTG
GCCGAGGCCTATTTGCGCGTTCCCGACGCCCCCACCCTCGATGCCCTGATCAAGGACAAGATCGGCGGCCGCGACTGGGC
CGAGCACGCTGGCGAAAGCGGCTCGATGCTGGTCAACGCCTCGACCTGGGGGCTGATGTTCACCGGCCGGCTTTATGGGG
AAAGCTGGGCCGAGGATACCTTGTTGGGATCGGTGCGCAAGATGGTGCGCCGGGTCGGCGAGCCGGTGGTGCGCACCGCC
GTTGCCCAATGCATGAAGATCATGGGCGCCCAGTTCGTTCTGGGGCGGACGATCGACGAGGCGTGGAGGAACGGCGGGCC
GCTGATCGAGAAGGGCTATACCTATTCCTTCGACATGCTGGGCGAGGCCGCCCGCACCGCCGCCGACGCCACCCATTATT
TCAAGGCCTATGCCAATGCCATCGCCGCCGTCGGCGCGCGGGCGACCCAGGCCGATGTCCATGCCAATTCGGGCATCTCG
GTCAAGCTGTCGGCCCTGCATCCGCGCTATGAGGAGGTCAACCGCGCCCGGGTGATGGCCGAACTGGTCCCCCGGCTGTC
GGCCCTGGCCGAGATGGCGGCGGCGGTCAATGTCGGCATGACGGTGGACGCCGAGGAGGCCGATCGCCTGGATCTGTCGC
TTTCGGTGATGGAGGCGGTGCTGCGCAATCCCAATCTGGCGGGATGGGGCGGCTTTGGTATCGTCGTCCAGGCCTATCTG
AAAAGCACCCTGCCGACCATCGACTGGATCATCGCCCTGGCCCGCGACCTCGATCGCCAACTGGCGGTGCGGCTGGTCAA
GGGCGCCTATTGGGACGCCGAGATTAAGACCGCCCAAAGCCTCGCCCTGCCGGCCTATCCGGTGTTCACCCGCAAGGCCT
CGACCGATGTGTCCTATATGGCCTCGGCCGCCCGGCTGCTAGGCGCCCAGGACCATATCTATCCGATGTTCGCCGGCCAT
AACGCCCATACCGCCTCGGCGGTGCTGGAAATGGCCGGACCGGACGCGGTGTTCGAGTTCCAGCGCCTGCATGGCATGGG
CGAAACCCTGCATGAGCTGCTGCGCCGCGATCATGGTCACCGCTGCCGCATCTATGCTCCGGTCGGCGTTCACAAGGATT
TGCTGGCCTATCTGGTGCGCCGCCTTTTGGAAAACGGCGCCAATAGCAGCTTCGTCAATCAGGCCCTTGATAAGGACGTG
CCGGCCGCCGAGCTGACCCGCGATCCGGCGACGGTGGTGGCCCAGGCCTCTTCGGTCGCCCATGCCGGCATTCCGCTGCC
GCCCGCCCTGTTCGGTGCCGAGCGGGCCAATTCCAAGGGCTGGAACCTGAATAATCCGCTGATGGCCGCCGAGTTGGACG
AGCGCCTGACGCCCTTCCGCGCCGCGCGTTGGTCGGCCGCGCCGATGATCGGCGCGACGCCGCCGCGCTCGGGTGGCGAG
GCGGTGACCAATCCCGCCGACCGCGACGAAACCGTGGGCTTCGTGGTGAGCGCGACGGCGAACGATGTCACCGTGGCCCT
GGAAACAACGACGCGGGCCTTCCCCAACTGGCGCGACCGGGCGCCGGCCGAGCGGGCCGCCCTCCTTGACCGCATCGCCG
CGCTCTATGAGGAACACGCCCCCGAACTGATCGCCCTGCTCAGCCGCGAAGCCGGCAAGACGCGCTGGGACGGCATTTTG
GAAGTGCGCGAGGCGGTGGATTTCTGCCGTTATTACGCGGCGCGAAGCCGGGCCGATCTGGCCGGCAGCGGTCGTAAGGG
GCGCGGCGTGTTCGTCTGCATCTCGCCCTGGAACTTCCCGCTGGCGATCTTCACTGGCCAGATCGCCGCCGCCCTGGTCA
GCGGCAACACGGTGATCGCCAAGCCGGCCGAGCAGACGCCGCTGATCGCCGCCCGCGCCGTGGCCCTGATGCGCGAGGCG
GGGGTGCCGCCCGAGGTTTTGGCCCTGCTGCCCGGCGAGGGTGCCAGCGTCGGCGCGGCGCTGACCGCCAGTCCCTTGGT
CGCCGGCGTCTGCTTCACCGGATCGACCGAGACCGCCATCGCCATCGACCGCGCCCAGGCTTCAGCCGGCACGGGCGGGG
CGCCGCTGATCGCCGAGACCGGCGGCCTCAACGCCATGATCGTTGATTCCACCGCCCTGCCCGAACATGCGGTGCGCGAT
ATCGTCGCCGGCGCCTTCCAAAGCGCCGGACAGCGCTGTTCGGCCCTGCGCGCCCTCTTCGTGCAAGAAGACATCGCCGA
CCACCTGCTGACCATGCTGGCCGGGGCGGTCCAGGAACTGGTGGTGGGCAATCCGTGGGAGGCGGTCACCGATGTCGGCC
CGGTGATCGATGCCGAGGCCAAGGCGGTGATCACCCGCCATTGCGAGGCCCTGACGGCGGCCGGACGGCGGCTGTTCGTC
CACGACAAGGCCAAGGCGGCCAAGGGCGGCGGCTTTGTTGCCCCCGTCGCCTTCTCGCTCGATCGCTTCGAGGATCTGAA
GAGCGAGATCTTCGGCCCGGTGCTTCATGTCATCCGCTTCCGCAATACCGAGATCGACGCCGTTGTCGACAGCATCAACG
CCGCTGGGTATGGCCTGACCCTGGGGATCCACAGCCGGGTCGACGCCCAGGTCGAACGCATCTGCAGCCGGGCCCGGGTT
GGCAATATCTATGTCAACCGCAACCAGATCGGCGCGGTGGTCGGTGTCCAGCCCTTCGGCGGCGAAGGGCTGTCGGGAAC
CGGCCCCAAGGCCGGCGGTCCGGGCTATCTGGAGCGCTTCACCATCGCCGCCCCGGTCGCCCTGCCCGAAGTCGCCTTGC
CGGCCTCCCATGGCGAGGACGCCGCGGCCGAGAATGCCCTGGACGCCGCGCGCTGGGCGGCCTCCGTCCAGCCGGCCTGG
GACGGGCGGAGCGATCGTCTGGCCATTCTGGAAGCGGCCCTGCGTGCCCTGCCCGAGGCCGCCCGCCCGACGGCGAGCGC
GGTTCTGGACCTAGCCAAGCCGCTGGTCGCCCCGCCGCTGGATCTGGTGGGGGTGACCGGGGAAAGCAACCGGTTGGCCC
TGCATGGGCGTGGCGTGGTTCTGTGCCTGGGCGGCGGCGAGCGGCCGGCGACGGCGCTGCTGGCCCAGGCGCTGCTGGGC
TTGGCGGCGGGTAACGCGGTGCTGCTGGCCGGGGATCCGGGGGCAGGGGTGATCGCCGCCCTGCGCAAGGCCCTGGCCGA
GGCCGGGCTTTCGGCTGGGCTGGTTCAATCGATCGTCGCCAGCGATCTTCCTGGGCTGCTGCGCGAGATGCCACGTCTGG
CCCTGGTCGCCCATGAGGGCGGCGTCGGTGGTGAAGGCCTGCGCGTCGCCCTGGCGGCGCGGTCGGGGGCCCGCGTGCCA
CTAGTCGCCCTGGTCGATGGCGTCGGCCGCTATGTGAGCGAACGGGTGGTGTCGATCGACACCACCGCCTCGGGCGGCAA
TGCCAGCCTGCTGATGCTCGACGAAGGATAA

Upstream 100 bases:

>100_bases
GCAAAATCAGAGACACTTCCTCCGGAAAATCGCCGAAACTTCGGGTCGATGGCCCTGCGGGTGCCATCCCCCCTCGCGCT
CCCGGTCAAGGATGTTCGGC

Downstream 100 bases:

>100_bases
GGGCCGGGGGTCATGAGCCGACAAGGAGCTTGAGAGCGATCGTCCACATGACCAGGGCGATGATCGCTTCCAGGCTCCGC
CAGGCCGAGGGCTTGGCGAA

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1236; Mature: 1235

Protein sequence:

>1236_residues
MSDLASLRLSLRREPLRDEAAVVADRLAALPLDADRRQAVSEAGRALVERMRASGEVTMMDNMLAEYGLSTDEGVALMCL
AEAYLRVPDAPTLDALIKDKIGGRDWAEHAGESGSMLVNASTWGLMFTGRLYGESWAEDTLLGSVRKMVRRVGEPVVRTA
VAQCMKIMGAQFVLGRTIDEAWRNGGPLIEKGYTYSFDMLGEAARTAADATHYFKAYANAIAAVGARATQADVHANSGIS
VKLSALHPRYEEVNRARVMAELVPRLSALAEMAAAVNVGMTVDAEEADRLDLSLSVMEAVLRNPNLAGWGGFGIVVQAYL
KSTLPTIDWIIALARDLDRQLAVRLVKGAYWDAEIKTAQSLALPAYPVFTRKASTDVSYMASAARLLGAQDHIYPMFAGH
NAHTASAVLEMAGPDAVFEFQRLHGMGETLHELLRRDHGHRCRIYAPVGVHKDLLAYLVRRLLENGANSSFVNQALDKDV
PAAELTRDPATVVAQASSVAHAGIPLPPALFGAERANSKGWNLNNPLMAAELDERLTPFRAARWSAAPMIGATPPRSGGE
AVTNPADRDETVGFVVSATANDVTVALETTTRAFPNWRDRAPAERAALLDRIAALYEEHAPELIALLSREAGKTRWDGIL
EVREAVDFCRYYAARSRADLAGSGRKGRGVFVCISPWNFPLAIFTGQIAAALVSGNTVIAKPAEQTPLIAARAVALMREA
GVPPEVLALLPGEGASVGAALTASPLVAGVCFTGSTETAIAIDRAQASAGTGGAPLIAETGGLNAMIVDSTALPEHAVRD
IVAGAFQSAGQRCSALRALFVQEDIADHLLTMLAGAVQELVVGNPWEAVTDVGPVIDAEAKAVITRHCEALTAAGRRLFV
HDKAKAAKGGGFVAPVAFSLDRFEDLKSEIFGPVLHVIRFRNTEIDAVVDSINAAGYGLTLGIHSRVDAQVERICSRARV
GNIYVNRNQIGAVVGVQPFGGEGLSGTGPKAGGPGYLERFTIAAPVALPEVALPASHGEDAAAENALDAARWAASVQPAW
DGRSDRLAILEAALRALPEAARPTASAVLDLAKPLVAPPLDLVGVTGESNRLALHGRGVVLCLGGGERPATALLAQALLG
LAAGNAVLLAGDPGAGVIAALRKALAEAGLSAGLVQSIVASDLPGLLREMPRLALVAHEGGVGGEGLRVALAARSGARVP
LVALVDGVGRYVSERVVSIDTTASGGNASLLMLDEG

Sequences:

>Translated_1236_residues
MSDLASLRLSLRREPLRDEAAVVADRLAALPLDADRRQAVSEAGRALVERMRASGEVTMMDNMLAEYGLSTDEGVALMCL
AEAYLRVPDAPTLDALIKDKIGGRDWAEHAGESGSMLVNASTWGLMFTGRLYGESWAEDTLLGSVRKMVRRVGEPVVRTA
VAQCMKIMGAQFVLGRTIDEAWRNGGPLIEKGYTYSFDMLGEAARTAADATHYFKAYANAIAAVGARATQADVHANSGIS
VKLSALHPRYEEVNRARVMAELVPRLSALAEMAAAVNVGMTVDAEEADRLDLSLSVMEAVLRNPNLAGWGGFGIVVQAYL
KSTLPTIDWIIALARDLDRQLAVRLVKGAYWDAEIKTAQSLALPAYPVFTRKASTDVSYMASAARLLGAQDHIYPMFAGH
NAHTASAVLEMAGPDAVFEFQRLHGMGETLHELLRRDHGHRCRIYAPVGVHKDLLAYLVRRLLENGANSSFVNQALDKDV
PAAELTRDPATVVAQASSVAHAGIPLPPALFGAERANSKGWNLNNPLMAAELDERLTPFRAARWSAAPMIGATPPRSGGE
AVTNPADRDETVGFVVSATANDVTVALETTTRAFPNWRDRAPAERAALLDRIAALYEEHAPELIALLSREAGKTRWDGIL
EVREAVDFCRYYAARSRADLAGSGRKGRGVFVCISPWNFPLAIFTGQIAAALVSGNTVIAKPAEQTPLIAARAVALMREA
GVPPEVLALLPGEGASVGAALTASPLVAGVCFTGSTETAIAIDRAQASAGTGGAPLIAETGGLNAMIVDSTALPEHAVRD
IVAGAFQSAGQRCSALRALFVQEDIADHLLTMLAGAVQELVVGNPWEAVTDVGPVIDAEAKAVITRHCEALTAAGRRLFV
HDKAKAAKGGGFVAPVAFSLDRFEDLKSEIFGPVLHVIRFRNTEIDAVVDSINAAGYGLTLGIHSRVDAQVERICSRARV
GNIYVNRNQIGAVVGVQPFGGEGLSGTGPKAGGPGYLERFTIAAPVALPEVALPASHGEDAAAENALDAARWAASVQPAW
DGRSDRLAILEAALRALPEAARPTASAVLDLAKPLVAPPLDLVGVTGESNRLALHGRGVVLCLGGGERPATALLAQALLG
LAAGNAVLLAGDPGAGVIAALRKALAEAGLSAGLVQSIVASDLPGLLREMPRLALVAHEGGVGGEGLRVALAARSGARVP
LVALVDGVGRYVSERVVSIDTTASGGNASLLMLDEG
>Mature_1235_residues
SDLASLRLSLRREPLRDEAAVVADRLAALPLDADRRQAVSEAGRALVERMRASGEVTMMDNMLAEYGLSTDEGVALMCLA
EAYLRVPDAPTLDALIKDKIGGRDWAEHAGESGSMLVNASTWGLMFTGRLYGESWAEDTLLGSVRKMVRRVGEPVVRTAV
AQCMKIMGAQFVLGRTIDEAWRNGGPLIEKGYTYSFDMLGEAARTAADATHYFKAYANAIAAVGARATQADVHANSGISV
KLSALHPRYEEVNRARVMAELVPRLSALAEMAAAVNVGMTVDAEEADRLDLSLSVMEAVLRNPNLAGWGGFGIVVQAYLK
STLPTIDWIIALARDLDRQLAVRLVKGAYWDAEIKTAQSLALPAYPVFTRKASTDVSYMASAARLLGAQDHIYPMFAGHN
AHTASAVLEMAGPDAVFEFQRLHGMGETLHELLRRDHGHRCRIYAPVGVHKDLLAYLVRRLLENGANSSFVNQALDKDVP
AAELTRDPATVVAQASSVAHAGIPLPPALFGAERANSKGWNLNNPLMAAELDERLTPFRAARWSAAPMIGATPPRSGGEA
VTNPADRDETVGFVVSATANDVTVALETTTRAFPNWRDRAPAERAALLDRIAALYEEHAPELIALLSREAGKTRWDGILE
VREAVDFCRYYAARSRADLAGSGRKGRGVFVCISPWNFPLAIFTGQIAAALVSGNTVIAKPAEQTPLIAARAVALMREAG
VPPEVLALLPGEGASVGAALTASPLVAGVCFTGSTETAIAIDRAQASAGTGGAPLIAETGGLNAMIVDSTALPEHAVRDI
VAGAFQSAGQRCSALRALFVQEDIADHLLTMLAGAVQELVVGNPWEAVTDVGPVIDAEAKAVITRHCEALTAAGRRLFVH
DKAKAAKGGGFVAPVAFSLDRFEDLKSEIFGPVLHVIRFRNTEIDAVVDSINAAGYGLTLGIHSRVDAQVERICSRARVG
NIYVNRNQIGAVVGVQPFGGEGLSGTGPKAGGPGYLERFTIAAPVALPEVALPASHGEDAAAENALDAARWAASVQPAWD
GRSDRLAILEAALRALPEAARPTASAVLDLAKPLVAPPLDLVGVTGESNRLALHGRGVVLCLGGGERPATALLAQALLGL
AAGNAVLLAGDPGAGVIAALRKALAEAGLSAGLVQSIVASDLPGLLREMPRLALVAHEGGVGGEGLRVALAARSGARVPL
VALVDGVGRYVSERVVSIDTTASGGNASLLMLDEG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777724, Length=455, Percent_Identity=32.7472527472527, Blast_Score=190, Evalue=8e-48,
Organism=Homo sapiens, GI153266822, Length=455, Percent_Identity=31.4285714285714, Blast_Score=187, Evalue=7e-47,
Organism=Homo sapiens, GI21361176, Length=454, Percent_Identity=32.15859030837, Blast_Score=184, Evalue=4e-46,
Organism=Homo sapiens, GI25777728, Length=411, Percent_Identity=32.8467153284672, Blast_Score=182, Evalue=2e-45,
Organism=Homo sapiens, GI25777730, Length=457, Percent_Identity=31.7286652078775, Blast_Score=178, Evalue=3e-44,
Organism=Homo sapiens, GI25777732, Length=465, Percent_Identity=32.9032258064516, Blast_Score=177, Evalue=8e-44,
Organism=Homo sapiens, GI238814322, Length=449, Percent_Identity=29.3986636971047, Blast_Score=172, Evalue=2e-42,
Organism=Homo sapiens, GI21614513, Length=414, Percent_Identity=30.4347826086957, Blast_Score=172, Evalue=3e-42,
Organism=Homo sapiens, GI12007648, Length=443, Percent_Identity=28.8939051918736, Blast_Score=164, Evalue=6e-40,
Organism=Homo sapiens, GI115387104, Length=456, Percent_Identity=28.2894736842105, Blast_Score=156, Evalue=1e-37,
Organism=Homo sapiens, GI4507229, Length=431, Percent_Identity=30.3944315545244, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI25777736, Length=483, Percent_Identity=30.0207039337474, Blast_Score=146, Evalue=1e-34,
Organism=Homo sapiens, GI25777734, Length=483, Percent_Identity=30.0207039337474, Blast_Score=146, Evalue=1e-34,
Organism=Homo sapiens, GI238859541, Length=483, Percent_Identity=30.0207039337474, Blast_Score=145, Evalue=3e-34,
Organism=Homo sapiens, GI25777726, Length=455, Percent_Identity=28.5714285714286, Blast_Score=142, Evalue=3e-33,
Organism=Homo sapiens, GI25777721, Length=445, Percent_Identity=29.6629213483146, Blast_Score=140, Evalue=1e-32,
Organism=Homo sapiens, GI310128093, Length=456, Percent_Identity=28.2894736842105, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI310128103, Length=456, Percent_Identity=28.2894736842105, Blast_Score=131, Evalue=3e-30,
Organism=Homo sapiens, GI188035924, Length=468, Percent_Identity=28.2051282051282, Blast_Score=131, Evalue=4e-30,
Organism=Homo sapiens, GI11095441, Length=423, Percent_Identity=28.1323877068558, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI310128091, Length=403, Percent_Identity=29.0322580645161, Blast_Score=117, Evalue=5e-26,
Organism=Homo sapiens, GI25952152, Length=245, Percent_Identity=33.0612244897959, Blast_Score=114, Evalue=5e-25,
Organism=Homo sapiens, GI206597441, Length=445, Percent_Identity=23.5955056179775, Blast_Score=91, Evalue=8e-18,
Organism=Homo sapiens, GI206597439, Length=445, Percent_Identity=23.5955056179775, Blast_Score=91, Evalue=8e-18,
Organism=Homo sapiens, GI22907049, Length=445, Percent_Identity=23.5955056179775, Blast_Score=91, Evalue=8e-18,
Organism=Homo sapiens, GI310128089, Length=324, Percent_Identity=28.0864197530864, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI4502043, Length=339, Percent_Identity=24.4837758112094, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI238814371, Length=339, Percent_Identity=24.4837758112094, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI71773324, Length=339, Percent_Identity=24.4837758112094, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI310128087, Length=281, Percent_Identity=28.8256227758007, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI310128095, Length=313, Percent_Identity=27.1565495207668, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI301500698, Length=273, Percent_Identity=26.007326007326, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI73466520, Length=348, Percent_Identity=23.5632183908046, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI4557303, Length=348, Percent_Identity=23.2758620689655, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI73695881, Length=337, Percent_Identity=24.0356083086053, Blast_Score=75, Evalue=6e-13,
Organism=Homo sapiens, GI73695879, Length=337, Percent_Identity=24.0356083086053, Blast_Score=75, Evalue=6e-13,
Organism=Homo sapiens, GI310128099, Length=216, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI310128101, Length=216, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI310128097, Length=248, Percent_Identity=28.6290322580645, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1787250, Length=1220, Percent_Identity=47.3770491803279, Blast_Score=981, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=462, Percent_Identity=32.4675324675325, Blast_Score=176, Evalue=7e-45,
Organism=Escherichia coli, GI87081896, Length=462, Percent_Identity=31.6017316017316, Blast_Score=176, Evalue=8e-45,
Organism=Escherichia coli, GI1787684, Length=455, Percent_Identity=31.4285714285714, Blast_Score=172, Evalue=1e-43,
Organism=Escherichia coli, GI1788042, Length=425, Percent_Identity=32.2352941176471, Blast_Score=170, Evalue=6e-43,
Organism=Escherichia coli, GI1787558, Length=429, Percent_Identity=32.4009324009324, Blast_Score=164, Evalue=5e-41,
Organism=Escherichia coli, GI1787715, Length=458, Percent_Identity=30.7860262008734, Blast_Score=150, Evalue=7e-37,
Organism=Escherichia coli, GI1786504, Length=447, Percent_Identity=27.5167785234899, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI87082295, Length=439, Percent_Identity=28.0182232346241, Blast_Score=128, Evalue=3e-30,
Organism=Escherichia coli, GI87081926, Length=416, Percent_Identity=25.2403846153846, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1787653, Length=361, Percent_Identity=24.3767313019391, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562198, Length=463, Percent_Identity=31.9654427645788, Blast_Score=178, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI133930964, Length=435, Percent_Identity=30.8045977011494, Blast_Score=178, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI25144435, Length=475, Percent_Identity=31.3684210526316, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI32564736, Length=422, Percent_Identity=31.7535545023697, Blast_Score=163, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17534447, Length=499, Percent_Identity=29.4589178356713, Blast_Score=159, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI115532534, Length=362, Percent_Identity=31.767955801105, Blast_Score=147, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI115534176, Length=463, Percent_Identity=29.5896328293737, Blast_Score=145, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI25143874, Length=446, Percent_Identity=27.5784753363229, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI25143876, Length=446, Percent_Identity=27.5784753363229, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71986308, Length=423, Percent_Identity=27.8959810874704, Blast_Score=135, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17551164, Length=430, Percent_Identity=27.4418604651163, Blast_Score=134, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17534119, Length=462, Percent_Identity=27.7056277056277, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71995606, Length=433, Percent_Identity=27.2517321016166, Blast_Score=126, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI71995613, Length=390, Percent_Identity=26.9230769230769, Blast_Score=114, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI32564151, Length=436, Percent_Identity=26.8348623853211, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17564084, Length=343, Percent_Identity=25.0728862973761, Blast_Score=91, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71990744, Length=320, Percent_Identity=27.5, Blast_Score=87, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25146391, Length=353, Percent_Identity=24.6458923512748, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32566756, Length=353, Percent_Identity=24.6458923512748, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25146394, Length=353, Percent_Identity=24.6458923512748, Blast_Score=86, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320917, Length=448, Percent_Identity=32.5892857142857, Blast_Score=187, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6324950, Length=448, Percent_Identity=31.4732142857143, Blast_Score=184, Evalue=6e-47,
Organism=Saccharomyces cerevisiae, GI6325196, Length=455, Percent_Identity=31.4285714285714, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6321826, Length=473, Percent_Identity=28.3298097251586, Blast_Score=159, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6323821, Length=483, Percent_Identity=28.7784679089027, Blast_Score=157, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6323822, Length=475, Percent_Identity=28.8421052631579, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319478, Length=449, Percent_Identity=27.6169265033408, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321828, Length=355, Percent_Identity=27.887323943662, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24650465, Length=461, Percent_Identity=31.0195227765727, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI281362580, Length=444, Percent_Identity=30.8558558558559, Blast_Score=170, Evalue=7e-42,
Organism=Drosophila melanogaster, GI62472918, Length=444, Percent_Identity=30.8558558558559, Blast_Score=170, Evalue=7e-42,
Organism=Drosophila melanogaster, GI62472926, Length=444, Percent_Identity=30.8558558558559, Blast_Score=170, Evalue=7e-42,
Organism=Drosophila melanogaster, GI62472936, Length=444, Percent_Identity=30.8558558558559, Blast_Score=170, Evalue=7e-42,
Organism=Drosophila melanogaster, GI21356737, Length=444, Percent_Identity=30.8558558558559, Blast_Score=170, Evalue=7e-42,
Organism=Drosophila melanogaster, GI20129399, Length=441, Percent_Identity=30.6122448979592, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24585660, Length=458, Percent_Identity=28.6026200873362, Blast_Score=164, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24668425, Length=485, Percent_Identity=27.2164948453608, Blast_Score=148, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24668417, Length=485, Percent_Identity=27.2164948453608, Blast_Score=148, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24668413, Length=485, Percent_Identity=27.2164948453608, Blast_Score=148, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24666674, Length=441, Percent_Identity=29.2517006802721, Blast_Score=133, Evalue=7e-31,
Organism=Drosophila melanogaster, GI28571806, Length=466, Percent_Identity=27.6824034334764, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571802, Length=466, Percent_Identity=27.6824034334764, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571800, Length=466, Percent_Identity=27.6824034334764, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571798, Length=466, Percent_Identity=27.6824034334764, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571796, Length=466, Percent_Identity=27.6824034334764, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571794, Length=466, Percent_Identity=27.6824034334764, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24638876, Length=424, Percent_Identity=28.0660377358491, Blast_Score=119, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24638878, Length=424, Percent_Identity=28.0660377358491, Blast_Score=119, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28574525, Length=478, Percent_Identity=23.4309623430962, Blast_Score=91, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 129864; Mature: 129733

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLASLRLSLRREPLRDEAAVVADRLAALPLDADRRQAVSEAGRALVERMRASGEVTMM
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEHH
DNMLAEYGLSTDEGVALMCLAEAYLRVPDAPTLDALIKDKIGGRDWAEHAGESGSMLVNA
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCEEEEE
STWGLMFTGRLYGESWAEDTLLGSVRKMVRRVGEPVVRTAVAQCMKIMGAQFVLGRTIDE
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHCCHHH
AWRNGGPLIEKGYTYSFDMLGEAARTAADATHYFKAYANAIAAVGARATQADVHANSGIS
HHCCCCCEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCE
VKLSALHPRYEEVNRARVMAELVPRLSALAEMAAAVNVGMTVDAEEADRLDLSLSVMEAV
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHH
LRNPNLAGWGGFGIVVQAYLKSTLPTIDWIIALARDLDRQLAVRLVKGAYWDAEIKTAQS
HCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LALPAYPVFTRKASTDVSYMASAARLLGAQDHIYPMFAGHNAHTASAVLEMAGPDAVFEF
HCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHH
QRLHGMGETLHELLRRDHGHRCRIYAPVGVHKDLLAYLVRRLLENGANSSFVNQALDKDV
HHHHCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
PAAELTRDPATVVAQASSVAHAGIPLPPALFGAERANSKGWNLNNPLMAAELDERLTPFR
CHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHCCHHCCCCCCCCCCCCCHHHHHHHCCCHH
AARWSAAPMIGATPPRSGGEAVTNPADRDETVGFVVSATANDVTVALETTTRAFPNWRDR
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCC
APAERAALLDRIAALYEEHAPELIALLSREAGKTRWDGILEVREAVDFCRYYAARSRADL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
AGSGRKGRGVFVCISPWNFPLAIFTGQIAAALVSGNTVIAKPAEQTPLIAARAVALMREA
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHC
GVPPEVLALLPGEGASVGAALTASPLVAGVCFTGSTETAIAIDRAQASAGTGGAPLIAET
CCCHHHHEEECCCCCCCCCHHHHHHHHEEEEECCCCCCEEEEECHHCCCCCCCCCEEEEC
GGLNAMIVDSTALPEHAVRDIVAGAFQSAGQRCSALRALFVQEDIADHLLTMLAGAVQEL
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVGNPWEAVTDVGPVIDAEAKAVITRHCEALTAAGRRLFVHDKAKAAKGGGFVAPVAFSL
HCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEHHHHHH
DRFEDLKSEIFGPVLHVIRFRNTEIDAVVDSINAAGYGLTLGIHSRVDAQVERICSRARV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHH
GNIYVNRNQIGAVVGVQPFGGEGLSGTGPKAGGPGYLERFTIAAPVALPEVALPASHGED
CEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHEECCCCCCCCCCCCCCCCC
AAAENALDAARWAASVQPAWDGRSDRLAILEAALRALPEAARPTASAVLDLAKPLVAPPL
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHCCCC
DLVGVTGESNRLALHGRGVVLCLGGGERPATALLAQALLGLAAGNAVLLAGDPGAGVIAA
CEEEECCCCCEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
LRKALAEAGLSAGLVQSIVASDLPGLLREMPRLALVAHEGGVGGEGLRVALAARSGARVP
HHHHHHHCCCHHHHHHHHHHHCCHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCCCCH
LVALVDGVGRYVSERVVSIDTTASGGNASLLMLDEG
HHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEECC
>Mature Secondary Structure 
SDLASLRLSLRREPLRDEAAVVADRLAALPLDADRRQAVSEAGRALVERMRASGEVTMM
CCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEHH
DNMLAEYGLSTDEGVALMCLAEAYLRVPDAPTLDALIKDKIGGRDWAEHAGESGSMLVNA
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCEEEEE
STWGLMFTGRLYGESWAEDTLLGSVRKMVRRVGEPVVRTAVAQCMKIMGAQFVLGRTIDE
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHCCHHH
AWRNGGPLIEKGYTYSFDMLGEAARTAADATHYFKAYANAIAAVGARATQADVHANSGIS
HHCCCCCEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCE
VKLSALHPRYEEVNRARVMAELVPRLSALAEMAAAVNVGMTVDAEEADRLDLSLSVMEAV
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHH
LRNPNLAGWGGFGIVVQAYLKSTLPTIDWIIALARDLDRQLAVRLVKGAYWDAEIKTAQS
HCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LALPAYPVFTRKASTDVSYMASAARLLGAQDHIYPMFAGHNAHTASAVLEMAGPDAVFEF
HCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHH
QRLHGMGETLHELLRRDHGHRCRIYAPVGVHKDLLAYLVRRLLENGANSSFVNQALDKDV
HHHHCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
PAAELTRDPATVVAQASSVAHAGIPLPPALFGAERANSKGWNLNNPLMAAELDERLTPFR
CHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHCCHHCCCCCCCCCCCCCHHHHHHHCCCHH
AARWSAAPMIGATPPRSGGEAVTNPADRDETVGFVVSATANDVTVALETTTRAFPNWRDR
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCC
APAERAALLDRIAALYEEHAPELIALLSREAGKTRWDGILEVREAVDFCRYYAARSRADL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
AGSGRKGRGVFVCISPWNFPLAIFTGQIAAALVSGNTVIAKPAEQTPLIAARAVALMREA
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHC
GVPPEVLALLPGEGASVGAALTASPLVAGVCFTGSTETAIAIDRAQASAGTGGAPLIAET
CCCHHHHEEECCCCCCCCCHHHHHHHHEEEEECCCCCCEEEEECHHCCCCCCCCCEEEEC
GGLNAMIVDSTALPEHAVRDIVAGAFQSAGQRCSALRALFVQEDIADHLLTMLAGAVQEL
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVGNPWEAVTDVGPVIDAEAKAVITRHCEALTAAGRRLFVHDKAKAAKGGGFVAPVAFSL
HCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEHHHHHH
DRFEDLKSEIFGPVLHVIRFRNTEIDAVVDSINAAGYGLTLGIHSRVDAQVERICSRARV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHH
GNIYVNRNQIGAVVGVQPFGGEGLSGTGPKAGGPGYLERFTIAAPVALPEVALPASHGED
CEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHEECCCCCCCCCCCCCCCCC
AAAENALDAARWAASVQPAWDGRSDRLAILEAALRALPEAARPTASAVLDLAKPLVAPPL
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHCCCC
DLVGVTGESNRLALHGRGVVLCLGGGERPATALLAQALLGLAAGNAVLLAGDPGAGVIAA
CEEEECCCCCEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
LRKALAEAGLSAGLVQSIVASDLPGLLREMPRLALVAHEGGVGGEGLRVALAARSGARVP
HHHHHHHCCCHHHHHHHHHHHCCHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCCCCH
LVALVDGVGRYVSERVVSIDTTASGGNASLLMLDEG
HHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]