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The map label for this gene is marC [H]

Identifier: 83591993

GI number: 83591993

Start: 774349

End: 775002

Strand: Reverse

Name: marC [H]

Synonym: Rru_A0654

Alternate gene names: 83591993

Gene position: 775002-774349 (Counterclockwise)

Preceding gene: 83591994

Following gene: 83591989

Centisome position: 17.8

GC content: 60.55

Gene sequence:

>654_bases
ATGGATTATTTCGGCCTTGCCGCGAAATACATTCCCTTCGTCACGCTCGGATTGCTGCCGATCATGAATCCGCTAAGCAC
CGTGCCGCTGTTTCTGGAATTGACCAAGCGCATGTCGCCCGAGCGCAAGCACCAGCAGGCGCGCCGGGCCTGTCTTTACG
CCCTGTCGATTCTCGCCGTGTTCTTGTTCATCGGCAACGGCATCATCACGCTGTTTGGCATCTCGCTGGCCGGCATCCGG
GTGGCCGGCGGGCTGATCATTCTGGTGCTGGCCTTCCGCATGCTGTTCTCGGGCGAAGGCGAAGAAGCCTCGATCGAAAC
GGAAGCCACCGAGATCAAGCGCGCCAACCTCGATTTCTCGTTCTCTCCGTTGGCCATGCCCAGCCTCGCCGGCCCGGGAT
CGATCGCCGTGGTCATGAGCTACGGCTCGCAGATCCCCGATGACGCCCTGGTCTTTGGCCATTTCATCGTCATCTGCGGC
ATCTCGATCACCGTGCTCATCGCCTATATCGCCCTTGCCGGCTCGGCCTGGATCGCCAAATTCCTCGGCGAGCACGGCAT
TCAGGCGGTCACCAAGATCATGGGCTTTCTGCTGACCTGCATCGCCGTCCAGTTCATCGCCTCGGGCATCCGCGATTTCT
CGCAAACCCTGTAG

Upstream 100 bases:

>100_bases
CACAAATGTCGCGTTTTAAAGGAAAATGGCCGTCCGCTAGCCTCCCCCGTTCCTATATTCCGGGCTCGACCCCAGGCGAA
TGCTTTTGCAGGATCTTCCC

Downstream 100 bases:

>100_bases
GGGAGCGGGCGGGCGGGGGTGCCAAGGCCCCGGACGCCCCCCTTCCCTTATTGGGCCGGCGCCAGATGGCGCAGGATGGT
CATGCGGGCCTTGCCGTGGG

Product: multiple drug resistance protein MarC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MDYFGLAAKYIPFVTLGLLPIMNPLSTVPLFLELTKRMSPERKHQQARRACLYALSILAVFLFIGNGIITLFGISLAGIR
VAGGLIILVLAFRMLFSGEGEEASIETEATEIKRANLDFSFSPLAMPSLAGPGSIAVVMSYGSQIPDDALVFGHFIVICG
ISITVLIAYIALAGSAWIAKFLGEHGIQAVTKIMGFLLTCIAVQFIASGIRDFSQTL

Sequences:

>Translated_217_residues
MDYFGLAAKYIPFVTLGLLPIMNPLSTVPLFLELTKRMSPERKHQQARRACLYALSILAVFLFIGNGIITLFGISLAGIR
VAGGLIILVLAFRMLFSGEGEEASIETEATEIKRANLDFSFSPLAMPSLAGPGSIAVVMSYGSQIPDDALVFGHFIVICG
ISITVLIAYIALAGSAWIAKFLGEHGIQAVTKIMGFLLTCIAVQFIASGIRDFSQTL
>Mature_217_residues
MDYFGLAAKYIPFVTLGLLPIMNPLSTVPLFLELTKRMSPERKHQQARRACLYALSILAVFLFIGNGIITLFGISLAGIR
VAGGLIILVLAFRMLFSGEGEEASIETEATEIKRANLDFSFSPLAMPSLAGPGSIAVVMSYGSQIPDDALVFGHFIVICG
ISITVLIAYIALAGSAWIAKFLGEHGIQAVTKIMGFLLTCIAVQFIASGIRDFSQTL

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787809, Length=201, Percent_Identity=37.3134328358209, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787494, Length=196, Percent_Identity=30.1020408163265, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1789842, Length=203, Percent_Identity=29.5566502463054, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 23307; Mature: 23307

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYFGLAAKYIPFVTLGLLPIMNPLSTVPLFLELTKRMSPERKHQQARRACLYALSILAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FLFIGNGIITLFGISLAGIRVAGGLIILVLAFRMLFSGEGEEASIETEATEIKRANLDFS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
FSPLAMPSLAGPGSIAVVMSYGSQIPDDALVFGHFIVICGISITVLIAYIALAGSAWIAK
CCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGEHGIQAVTKIMGFLLTCIAVQFIASGIRDFSQTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDYFGLAAKYIPFVTLGLLPIMNPLSTVPLFLELTKRMSPERKHQQARRACLYALSILAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FLFIGNGIITLFGISLAGIRVAGGLIILVLAFRMLFSGEGEEASIETEATEIKRANLDFS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
FSPLAMPSLAGPGSIAVVMSYGSQIPDDALVFGHFIVICGISITVLIAYIALAGSAWIAK
CCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGEHGIQAVTKIMGFLLTCIAVQFIASGIRDFSQTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA