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The map label for this gene is tdcB [H]

Identifier: 83591986

GI number: 83591986

Start: 769110

End: 770102

Strand: Direct

Name: tdcB [H]

Synonym: Rru_A0647

Alternate gene names: 83591986

Gene position: 769110-770102 (Clockwise)

Preceding gene: 83591985

Following gene: 83591990

Centisome position: 17.67

GC content: 71.4

Gene sequence:

>993_bases
ATGACCCGGCCCTTGCCCGAGACTCCCGGGGTCGGCGCCCAGGACGTGGTCGATGCCGGCCACCGCCTGAAGGGTCTTGT
CGTCACCACGCCGCTTGTCGAAAGCCCGGTGCTCAACGCCAGCATCGGTGGCCGGCTGCTGGTCAAGGCCGAATGCCTGC
AGCGGACGGGATCGTTCAAGATGCGCGGGGCGACCAACGCCCTGGCCCAGATGGACGACGCGGCGCGGGCGCGCGGCGTC
ATCACCCATTCGTCGGGCAATCATGGTCAGGCCTTGGCCTCGGCCGCCCGGGCCTTCGGCCTGCGGGCGACCGTGGTGAT
GCCCGATGACGCGCCCGCCCTCAAGATCGAGCTGACCCGGGCCCATGGCGCCGAGGTGGTCTTCTGTCCGCGCCACGCCC
GCGAGCAGACGGTGGCCCGGCTAGCCGGCGAAAGCGGCGCCGTGGTGATCCATCCCTATGAGACCCCCGCCGTCATCGCC
GGCCAGGGGACGGTGGGCCTGGAAATCGTCGAGCAATGCGCCGCCATCGGCGTGGTGCCCGATCAGGTGCTGGTCTGCTG
TGGCGGCGGCGGTCTGACCGCCGGGGTGGCCCTGGCCATCGACCGGCTGCTGCCCGGCGTGCCGGTGATCGCCGTCGAGC
CCGAGGGCTGGGACGATACCAAGCGCTCCCTGGCCGCCGGTGCTATCGTCGCCAATGACGGTCTGACGGCCACGGCCTGC
GACGCCTTGCAGGCGATGTGTCCGGGCACCCTCAGCTTCTCGCTCAATCGCCATCTGCTGGCCGGGGCGGTGAGCGTGGA
CGAGGCGATGGTGCGCCACGCCATGCGCCAAGCCTTCGTTCATCTCAAGCTGGTGGCCGAACCCGGCGGCGCCGTGGCCC
TGGCCGCCGCCCTGGCCGGCAAGGTCGAGACCGCCGATCGCCTCAGCGTCGTCGTGCTCTCGGGCGGCAATGTCGATCCC
GGCCGCTTCGCGAGCGTGCTGGCCGGGGATTAG

Upstream 100 bases:

>100_bases
GCGACCGCGCCTATCAGGCGGTCGACGCCCTGGACTGGCCGGGCGGCTTTTGCCGGCGTGATATCGGGTGGCGGGCCCTG
GCCCGCGAGGAGGGCGGACG

Downstream 100 bases:

>100_bases
GGCAAATCCCCTGGCGCTTTGGACCTGAGCGTGACGGCGATTTGCTTCCCGCTCAGCCTCCCGAGGCGGCGGCCTCGTCT
TCCGGGCGCCACATGCATAT

Product: L-threonine ammonia-lyase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTRPLPETPGVGAQDVVDAGHRLKGLVVTTPLVESPVLNASIGGRLLVKAECLQRTGSFKMRGATNALAQMDDAARARGV
ITHSSGNHGQALASAARAFGLRATVVMPDDAPALKIELTRAHGAEVVFCPRHAREQTVARLAGESGAVVIHPYETPAVIA
GQGTVGLEIVEQCAAIGVVPDQVLVCCGGGGLTAGVALAIDRLLPGVPVIAVEPEGWDDTKRSLAAGAIVANDGLTATAC
DALQAMCPGTLSFSLNRHLLAGAVSVDEAMVRHAMRQAFVHLKLVAEPGGAVALAAALAGKVETADRLSVVVLSGGNVDP
GRFASVLAGD

Sequences:

>Translated_330_residues
MTRPLPETPGVGAQDVVDAGHRLKGLVVTTPLVESPVLNASIGGRLLVKAECLQRTGSFKMRGATNALAQMDDAARARGV
ITHSSGNHGQALASAARAFGLRATVVMPDDAPALKIELTRAHGAEVVFCPRHAREQTVARLAGESGAVVIHPYETPAVIA
GQGTVGLEIVEQCAAIGVVPDQVLVCCGGGGLTAGVALAIDRLLPGVPVIAVEPEGWDDTKRSLAAGAIVANDGLTATAC
DALQAMCPGTLSFSLNRHLLAGAVSVDEAMVRHAMRQAFVHLKLVAEPGGAVALAAALAGKVETADRLSVVVLSGGNVDP
GRFASVLAGD
>Mature_329_residues
TRPLPETPGVGAQDVVDAGHRLKGLVVTTPLVESPVLNASIGGRLLVKAECLQRTGSFKMRGATNALAQMDDAARARGVI
THSSGNHGQALASAARAFGLRATVVMPDDAPALKIELTRAHGAEVVFCPRHAREQTVARLAGESGAVVIHPYETPAVIAG
QGTVGLEIVEQCAAIGVVPDQVLVCCGGGGLTAGVALAIDRLLPGVPVIAVEPEGWDDTKRSLAAGAIVANDGLTATACD
ALQAMCPGTLSFSLNRHLLAGAVSVDEAMVRHAMRQAFVHLKLVAEPGGAVALAAALAGKVETADRLSVVVLSGGNVDPG
RFASVLAGD

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=313, Percent_Identity=36.4217252396166, Blast_Score=188, Evalue=6e-48,
Organism=Homo sapiens, GI295821202, Length=204, Percent_Identity=30.8823529411765, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI295821200, Length=204, Percent_Identity=30.8823529411765, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4557415, Length=204, Percent_Identity=30.8823529411765, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789505, Length=332, Percent_Identity=36.144578313253, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1790207, Length=297, Percent_Identity=36.7003367003367, Blast_Score=122, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17508781, Length=299, Percent_Identity=36.4548494983278, Blast_Score=154, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI71991565, Length=327, Percent_Identity=36.3914373088685, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17537387, Length=318, Percent_Identity=34.2767295597484, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6322631, Length=317, Percent_Identity=39.1167192429022, Blast_Score=199, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6320930, Length=306, Percent_Identity=31.0457516339869, Blast_Score=112, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6319788, Length=291, Percent_Identity=25.4295532646048, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355833, Length=331, Percent_Identity=35.6495468277946, Blast_Score=114, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 33545; Mature: 33414

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPLPETPGVGAQDVVDAGHRLKGLVVTTPLVESPVLNASIGGRLLVKAECLQRTGSFK
CCCCCCCCCCCCHHHHHHCCHHCCEEEEECCCCCCCCCCCCCCCEEEEEEHHHHHCCCEE
MRGATNALAQMDDAARARGVITHSSGNHGQALASAARAFGLRATVVMPDDAPALKIELTR
ECCCHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCEEEEEEEE
AHGAEVVFCPRHAREQTVARLAGESGAVVIHPYETPAVIAGQGTVGLEIVEQCAAIGVVP
CCCCEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHCCCCC
DQVLVCCGGGGLTAGVALAIDRLLPGVPVIAVEPEGWDDTKRSLAAGAIVANDGLTATAC
CCEEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCEEEECCCCCHHHH
DALQAMCPGTLSFSLNRHLLAGAVSVDEAMVRHAMRQAFVHLKLVAEPGGAVALAAALAG
HHHHHHCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHC
KVETADRLSVVVLSGGNVDPGRFASVLAGD
CCCCCCCEEEEEEECCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TRPLPETPGVGAQDVVDAGHRLKGLVVTTPLVESPVLNASIGGRLLVKAECLQRTGSFK
CCCCCCCCCCCHHHHHHCCHHCCEEEEECCCCCCCCCCCCCCCEEEEEEHHHHHCCCEE
MRGATNALAQMDDAARARGVITHSSGNHGQALASAARAFGLRATVVMPDDAPALKIELTR
ECCCHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCEEEEEEEE
AHGAEVVFCPRHAREQTVARLAGESGAVVIHPYETPAVIAGQGTVGLEIVEQCAAIGVVP
CCCCEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHCCCCC
DQVLVCCGGGGLTAGVALAIDRLLPGVPVIAVEPEGWDDTKRSLAAGAIVANDGLTATAC
CCEEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCEEEECCCCCHHHH
DALQAMCPGTLSFSLNRHLLAGAVSVDEAMVRHAMRQAFVHLKLVAEPGGAVALAAALAG
HHHHHHCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHC
KVETADRLSVVVLSGGNVDPGRFASVLAGD
CCCCCCCEEEEEEECCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA