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The map label for this gene is waaA [H]

Identifier: 83591920

GI number: 83591920

Start: 690002

End: 691318

Strand: Direct

Name: waaA [H]

Synonym: Rru_A0581

Alternate gene names: 83591920

Gene position: 690002-691318 (Clockwise)

Preceding gene: 83591919

Following gene: 83591921

Centisome position: 15.85

GC content: 69.7

Gene sequence:

>1317_bases
ATGTCGCTTTACAGTTTTTACCGGCTTCTAACCGTTCTCGGCGGTCCCGGTATCGATCTTTTGCTGCGCTACCGACGGTC
GCGCGGCAAGGAGGATGTTGATCGTCTGGGCGAAAGACTGGGCGAACCGGGTCTGGCGCGGCCGGTCGGGCCGCTGGTCT
GGCTGCATGGGGCGAGTGTGGGCGAGGCCAAGGCCCTCGTGCCGCTGATTACCCGGCTGCGCGCCGAGCGGCCGCGTCTT
GGCGTGCTGTTGACCACCGGCACCGTGACCTCGGCCCGGGTGGTCGGCGACCATCTGCCGCGCGGCGCCATTCACCAGTA
TCTGCCCGTCGACAAGCCCGGCGCCATCCGCCGCTTCCTCGACCATTGGGCCCCCGATCTGATGCTGTGGAGCGAGTCCG
ATTTCTGGCCCAATCTGATGGTCGAAGCCGGGGCGCGCCAGATCCCCATGGTGCTGCTCAACGGCCGGGTCTCGGACCGC
TCCTACGATTCGTGGCGGCGCCACCGCCGGCTGATCGGGCGCATGCTTGATGGCTTCGCCCTGTGCCTGGGCCAGACCGA
GGAGGACGCCCGCCGTCTGGCCGACTTGGGGGCCGCCCATACCGGCTGCGTGGGCAATCTGAAATTCGCCAACCCCGCCG
ATCCGGCCGAGCCCCGCGCCCTGGCCGCTGCCCTGGCCGCCCTTGATGACCGGCCGCGCTGGATCGCCGCCAGCACCCAT
CCCGGCGAGGAGGGGATCGCCGGGCGTTTGCACAAAAGCCTGAAGGCCAAGCATCCGGGCTTGCTGACCATCGTCGTTCC
CCGCCATCCCCATCGCGCCGCCGAGGTCGCCGCCGAACTGACCGCCTTGGGGCTGGGCGTGCGTCGGCGCAGCGAGGGCT
GGCCGGCGAGCACCGATGATGTGCTGCTTGGCGACACCATGGGCGAGATGGGGCTTTACCTGCGCTTGGCCCCGGTGGTT
TTCATGGGCAAGACCCTGGCCAAGACCGGGGGACAAAATCCCCTGGAGCCGGCCTTGCTGGAGTCCGCCGTTTTGTGGGG
GCCGGGAATGACCAATTTCGCCGAGATCGCCGCCCGCATGCAGGCCGTGGGCGCCGCCCTTAGTGTCGCCGACGAGGCCG
AGCTTGGGGAAAAGGTGTCGCTGCTGCTCACCGATGCCGTCGCCCGTCGCCGCATGGCCCGCGCCGCCCGGCTGTGGGCC
GAGGGCGAAAGGGCGGTTCTCGACCGCGTCCTTGGCTGCCTTGCCCCGTTCCTCGACGTCCTGACGCCGCTTGCCCCCAC
CCCCTCCCTGCGCGAGGCCGGCGGTGCGCGCCCCTGA

Upstream 100 bases:

>100_bases
TTTGCCGGTGGGGTGGGAAAGGCCGCTGGCGGGCTCTTCCTTTGCCCTTCGCTCGCGGGCGTGCTACATCGCCTCGCGCC
CAGGCAAGAATGGCCCGATC

Downstream 100 bases:

>100_bases
GTTCTGGCATAAGGACGGCTTCGCCGCCCGCCTGCTCGAACCGGTCGGGCTGGTCTATGCGGCGCTGACCCGCCACCGGG
TGGCCCGTCCGCCCGGGGTG

Product: three-deoxy-D-manno-octulosonic-acid transferase-like

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MSLYSFYRLLTVLGGPGIDLLLRYRRSRGKEDVDRLGERLGEPGLARPVGPLVWLHGASVGEAKALVPLITRLRAERPRL
GVLLTTGTVTSARVVGDHLPRGAIHQYLPVDKPGAIRRFLDHWAPDLMLWSESDFWPNLMVEAGARQIPMVLLNGRVSDR
SYDSWRRHRRLIGRMLDGFALCLGQTEEDARRLADLGAAHTGCVGNLKFANPADPAEPRALAAALAALDDRPRWIAASTH
PGEEGIAGRLHKSLKAKHPGLLTIVVPRHPHRAAEVAAELTALGLGVRRRSEGWPASTDDVLLGDTMGEMGLYLRLAPVV
FMGKTLAKTGGQNPLEPALLESAVLWGPGMTNFAEIAARMQAVGAALSVADEAELGEKVSLLLTDAVARRRMARAARLWA
EGERAVLDRVLGCLAPFLDVLTPLAPTPSLREAGGARP

Sequences:

>Translated_438_residues
MSLYSFYRLLTVLGGPGIDLLLRYRRSRGKEDVDRLGERLGEPGLARPVGPLVWLHGASVGEAKALVPLITRLRAERPRL
GVLLTTGTVTSARVVGDHLPRGAIHQYLPVDKPGAIRRFLDHWAPDLMLWSESDFWPNLMVEAGARQIPMVLLNGRVSDR
SYDSWRRHRRLIGRMLDGFALCLGQTEEDARRLADLGAAHTGCVGNLKFANPADPAEPRALAAALAALDDRPRWIAASTH
PGEEGIAGRLHKSLKAKHPGLLTIVVPRHPHRAAEVAAELTALGLGVRRRSEGWPASTDDVLLGDTMGEMGLYLRLAPVV
FMGKTLAKTGGQNPLEPALLESAVLWGPGMTNFAEIAARMQAVGAALSVADEAELGEKVSLLLTDAVARRRMARAARLWA
EGERAVLDRVLGCLAPFLDVLTPLAPTPSLREAGGARP
>Mature_437_residues
SLYSFYRLLTVLGGPGIDLLLRYRRSRGKEDVDRLGERLGEPGLARPVGPLVWLHGASVGEAKALVPLITRLRAERPRLG
VLLTTGTVTSARVVGDHLPRGAIHQYLPVDKPGAIRRFLDHWAPDLMLWSESDFWPNLMVEAGARQIPMVLLNGRVSDRS
YDSWRRHRRLIGRMLDGFALCLGQTEEDARRLADLGAAHTGCVGNLKFANPADPAEPRALAAALAALDDRPRWIAASTHP
GEEGIAGRLHKSLKAKHPGLLTIVVPRHPHRAAEVAAELTALGLGVRRRSEGWPASTDDVLLGDTMGEMGLYLRLAPVVF
MGKTLAKTGGQNPLEPALLESAVLWGPGMTNFAEIAARMQAVGAALSVADEAELGEKVSLLLTDAVARRRMARAARLWAE
GERAVLDRVLGCLAPFLDVLTPLAPTPSLREAGGARP

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA) [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=422, Percent_Identity=36.7298578199052, Blast_Score=228, Evalue=8e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007507 [H]

Pfam domain/function: PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 47388; Mature: 47256

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLYSFYRLLTVLGGPGIDLLLRYRRSRGKEDVDRLGERLGEPGLARPVGPLVWLHGASV
CCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
GEAKALVPLITRLRAERPRLGVLLTTGTVTSARVVGDHLPRGAIHQYLPVDKPGAIRRFL
CHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHH
DHWAPDLMLWSESDFWPNLMVEAGARQIPMVLLNGRVSDRSYDSWRRHRRLIGRMLDGFA
HHCCCCEEEECCCCCCCHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
LCLGQTEEDARRLADLGAAHTGCVGNLKFANPADPAEPRALAAALAALDDRPRWIAASTH
HHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCC
PGEEGIAGRLHKSLKAKHPGLLTIVVPRHPHRAAEVAAELTALGLGVRRRSEGWPASTDD
CCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VLLGDTMGEMGLYLRLAPVVFMGKTLAKTGGQNPLEPALLESAVLWGPGMTNFAEIAARM
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
QAVGAALSVADEAELGEKVSLLLTDAVARRRMARAARLWAEGERAVLDRVLGCLAPFLDV
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LTPLAPTPSLREAGGARP
HCCCCCCCCHHHCCCCCC
>Mature Secondary Structure 
SLYSFYRLLTVLGGPGIDLLLRYRRSRGKEDVDRLGERLGEPGLARPVGPLVWLHGASV
CHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
GEAKALVPLITRLRAERPRLGVLLTTGTVTSARVVGDHLPRGAIHQYLPVDKPGAIRRFL
CHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHH
DHWAPDLMLWSESDFWPNLMVEAGARQIPMVLLNGRVSDRSYDSWRRHRRLIGRMLDGFA
HHCCCCEEEECCCCCCCHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
LCLGQTEEDARRLADLGAAHTGCVGNLKFANPADPAEPRALAAALAALDDRPRWIAASTH
HHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCC
PGEEGIAGRLHKSLKAKHPGLLTIVVPRHPHRAAEVAAELTALGLGVRRRSEGWPASTDD
CCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VLLGDTMGEMGLYLRLAPVVFMGKTLAKTGGQNPLEPALLESAVLWGPGMTNFAEIAARM
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
QAVGAALSVADEAELGEKVSLLLTDAVARRRMARAARLWAEGERAVLDRVLGCLAPFLDV
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LTPLAPTPSLREAGGARP
HCCCCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA