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The map label for this gene is 83591650

Identifier: 83591650

GI number: 83591650

Start: 377880

End: 379268

Strand: Direct

Name: 83591650

Synonym: Rru_A0310

Alternate gene names: NA

Gene position: 377880-379268 (Clockwise)

Preceding gene: 83591649

Following gene: 83591651

Centisome position: 8.68

GC content: 67.31

Gene sequence:

>1389_bases
ATGTCGATCCAACCGACCGTAACCATCGATCCCGAGCTGTGTACCGGATGTGGGCGGTGTGTTGAAACCTGTCCGGTTCA
GGCGATCGCCGGCAGCCGGGGCAAGGCCCATGAGATCGAGGCGGCGGCTTGCGTGTCCTGCGGGCGGTGCGTCGCCACCT
GCGCCGCCTTTGATTCGATTTTCGACGCCTTCCCGACGCCGCGCCCGGTCCGCCTGAAACGGCGCGGCCTTCCCGGTTCG
CTGAAGGAGCCGTTGTTCGCCGCCCATGATCCCAGCCGGATCGAGGCGGTGCGCAAGGCCTTCGCCACCCCCAAGCGGAT
GACGGTGATGCAGGTCGACACCATGGCCTGCGTCGCCCTGGCCGAGGATTTCGGCCTGCCCCCGGGCAGCCTGTCGCCGC
TCAAGATCGCCAGCGCCGCCCGCCAGCTGGGCTTCGATCGGGTGTACCGCACCAGTTTCCCCGCCGGTCTGGCGGTGTTG
GAAACCGCCCACGAGATGGCGGCCCGTCTGGCCAATGGCGGCAATCTGCCGGTGATCAATTCGTCGTGTCCGGCGGTGGT
GGCCTTCCTGGAACGGCGCTATCCCGAGCTTTTGCATTACCTGTCGACGGTGAAGTCCCCCCATCAGATCGCCGGCGCCC
TCTACAACTCCTATCTCGCCGATGCCGCCAATCTCGCCCCGGCGAATATTCACAAGGTCTCGGTCGTCGCCTGCCTGTCC
CATAAGGCCGAGGCCGAACGTCCCGAGATGATGACCTGCGGCTGCCCGGATATCGATACGGTGCTGACCGCCCGCGAGCT
CGCCATCCTGATCAAGGACGCCGGCATCGACGTGCCTTTGCTGGGCGATGGCGAATTCGACAACGATTTTCCCGAGATCG
AAGGCCTCGACACCCTTTATTGCGCTCCCGGCGATGTGTCGCGGGCGGTGCTGGGCGCCGGGCGCTGGTTCCTGGGCCAG
GGCGAAGGCGTCGGCGCGCCGGCGGGCGAAACCGTCGAGGTGCTTGACGAGGCCACCCGGCTGACCCGGCTGGCCTATCC
CGGCGGCACGCTTCAGGCGCTGACGGTGGCCGGCTTCGACAAGGCCGTTCCCTATCTTGAAGCGATCAAGGCCGGGCGCA
ATGCCTTCCAGTTCCTGGAGATCGCGTCTTGTCCCCAGGGCTGCGCCTCGGGGGCGGGGTTGCCCAAGGTGCTGCTGGAA
ACCGAGAAACCGGCGCGCTACCGCGCCCGGATCGAGAACCTGCCGCCGGCGGCGCCCGAGGCGTGGAGCCGGCTTCCCGG
CCATCCGTCGATCGTCGCCCTCTATGGCGGCTACTTCGGCAAGGCCATCGGCGACAAGTCGAACCGCCGTCTCCACACCC
AATACGCCGAACCTGCGGCCGCCCCCTAA

Upstream 100 bases:

>100_bases
TCGATCCCGCCGCCGAAGTGGCGCGGCGCGCCCTGGGCGCCGTCGAGGATCTGGTGTCCAGCATGAAATTCTCCGGTCTG
TGAGCCAGAGGGATATGAGC

Downstream 100 bases:

>100_bases
CTCCCTCCCTCGCCGCGCCCCGTCGCTTGGGGCGCGGACCCCACGGTGTTGCAACGATAAGACCGATTGAGGCGAACGAT
GAGTTACTACACTCCCAAGG

Product: ferredoxin hydrogenase

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSIQPTVTIDPELCTGCGRCVETCPVQAIAGSRGKAHEIEAAACVSCGRCVATCAAFDSIFDAFPTPRPVRLKRRGLPGS
LKEPLFAAHDPSRIEAVRKAFATPKRMTVMQVDTMACVALAEDFGLPPGSLSPLKIASAARQLGFDRVYRTSFPAGLAVL
ETAHEMAARLANGGNLPVINSSCPAVVAFLERRYPELLHYLSTVKSPHQIAGALYNSYLADAANLAPANIHKVSVVACLS
HKAEAERPEMMTCGCPDIDTVLTARELAILIKDAGIDVPLLGDGEFDNDFPEIEGLDTLYCAPGDVSRAVLGAGRWFLGQ
GEGVGAPAGETVEVLDEATRLTRLAYPGGTLQALTVAGFDKAVPYLEAIKAGRNAFQFLEIASCPQGCASGAGLPKVLLE
TEKPARYRARIENLPPAAPEAWSRLPGHPSIVALYGGYFGKAIGDKSNRRLHTQYAEPAAAP

Sequences:

>Translated_462_residues
MSIQPTVTIDPELCTGCGRCVETCPVQAIAGSRGKAHEIEAAACVSCGRCVATCAAFDSIFDAFPTPRPVRLKRRGLPGS
LKEPLFAAHDPSRIEAVRKAFATPKRMTVMQVDTMACVALAEDFGLPPGSLSPLKIASAARQLGFDRVYRTSFPAGLAVL
ETAHEMAARLANGGNLPVINSSCPAVVAFLERRYPELLHYLSTVKSPHQIAGALYNSYLADAANLAPANIHKVSVVACLS
HKAEAERPEMMTCGCPDIDTVLTARELAILIKDAGIDVPLLGDGEFDNDFPEIEGLDTLYCAPGDVSRAVLGAGRWFLGQ
GEGVGAPAGETVEVLDEATRLTRLAYPGGTLQALTVAGFDKAVPYLEAIKAGRNAFQFLEIASCPQGCASGAGLPKVLLE
TEKPARYRARIENLPPAAPEAWSRLPGHPSIVALYGGYFGKAIGDKSNRRLHTQYAEPAAAP
>Mature_461_residues
SIQPTVTIDPELCTGCGRCVETCPVQAIAGSRGKAHEIEAAACVSCGRCVATCAAFDSIFDAFPTPRPVRLKRRGLPGSL
KEPLFAAHDPSRIEAVRKAFATPKRMTVMQVDTMACVALAEDFGLPPGSLSPLKIASAARQLGFDRVYRTSFPAGLAVLE
TAHEMAARLANGGNLPVINSSCPAVVAFLERRYPELLHYLSTVKSPHQIAGALYNSYLADAANLAPANIHKVSVVACLSH
KAEAERPEMMTCGCPDIDTVLTARELAILIKDAGIDVPLLGDGEFDNDFPEIEGLDTLYCAPGDVSRAVLGAGRWFLGQG
EGVGAPAGETVEVLDEATRLTRLAYPGGTLQALTVAGFDKAVPYLEAIKAGRNAFQFLEIASCPQGCASGAGLPKVLLET
EKPARYRARIENLPPAAPEAWSRLPGHPSIVALYGGYFGKAIGDKSNRRLHTQYAEPAAAP

Specific function: Unknown

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=386, Percent_Identity=26.1658031088083, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI134284357, Length=269, Percent_Identity=27.5092936802974, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI6912524, Length=323, Percent_Identity=26.625386996904, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI84452151, Length=323, Percent_Identity=26.625386996904, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71995015, Length=340, Percent_Identity=26.4705882352941, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324089, Length=115, Percent_Identity=30.4347826086957, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007464, Length=331, Percent_Identity=27.190332326284, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI116007468, Length=331, Percent_Identity=27.190332326284, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI116007470, Length=339, Percent_Identity=27.4336283185841, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI116007466, Length=339, Percent_Identity=27.4336283185841, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 48936; Mature: 48804

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQPTVTIDPELCTGCGRCVETCPVQAIAGSRGKAHEIEAAACVSCGRCVATCAAFDSI
CCCCCCEEECHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FDAFPTPRPVRLKRRGLPGSLKEPLFAAHDPSRIEAVRKAFATPKRMTVMQVDTMACVAL
HHHCCCCCCCHHHCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHH
AEDFGLPPGSLSPLKIASAARQLGFDRVYRTSFPAGLAVLETAHEMAARLANGGNLPVIN
HHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEC
SSCPAVVAFLERRYPELLHYLSTVKSPHQIAGALYNSYLADAANLAPANIHKVSVVACLS
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
HKAEAERPEMMTCGCPDIDTVLTARELAILIKDAGIDVPLLGDGEFDNDFPEIEGLDTLY
HHHHCCCCCEEECCCCCHHHHHHHHHHEEEEEECCCCEEEECCCCCCCCCCCCCCCCEEE
CAPGDVSRAVLGAGRWFLGQGEGVGAPAGETVEVLDEATRLTRLAYPGGTLQALTVAGFD
ECCCCHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCH
KAVPYLEAIKAGRNAFQFLEIASCPQGCASGAGLPKVLLETEKPARYRARIENLPPAAPE
HHHHHHHHHHHCCHHHHHHHHHCCCCHHHCCCCCCHHHHCCCCCHHHHHHHHCCCCCCCH
AWSRLPGHPSIVALYGGYFGKAIGDKSNRRLHTQYAEPAAAP
HHHHCCCCCCEEEEECCHHHHHHCCCCCCEEEEHHCCCCCCC
>Mature Secondary Structure 
SIQPTVTIDPELCTGCGRCVETCPVQAIAGSRGKAHEIEAAACVSCGRCVATCAAFDSI
CCCCCEEECHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FDAFPTPRPVRLKRRGLPGSLKEPLFAAHDPSRIEAVRKAFATPKRMTVMQVDTMACVAL
HHHCCCCCCCHHHCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHH
AEDFGLPPGSLSPLKIASAARQLGFDRVYRTSFPAGLAVLETAHEMAARLANGGNLPVIN
HHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEC
SSCPAVVAFLERRYPELLHYLSTVKSPHQIAGALYNSYLADAANLAPANIHKVSVVACLS
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
HKAEAERPEMMTCGCPDIDTVLTARELAILIKDAGIDVPLLGDGEFDNDFPEIEGLDTLY
HHHHCCCCCEEECCCCCHHHHHHHHHHEEEEEECCCCEEEECCCCCCCCCCCCCCCCEEE
CAPGDVSRAVLGAGRWFLGQGEGVGAPAGETVEVLDEATRLTRLAYPGGTLQALTVAGFD
ECCCCHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCH
KAVPYLEAIKAGRNAFQFLEIASCPQGCASGAGLPKVLLETEKPARYRARIENLPPAAPE
HHHHHHHHHHHCCHHHHHHHHHCCCCHHHCCCCCCHHHHCCCCCHHHHHHHHCCCCCCCH
AWSRLPGHPSIVALYGGYFGKAIGDKSNRRLHTQYAEPAAAP
HHHHCCCCCCEEEEECCHHHHHHCCCCCCEEEEHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]