Click here to switch to the map view.

The map label for this gene is accA [H]

Identifier: 83591558

GI number: 83591558

Start: 270069

End: 271034

Strand: Direct

Name: accA [H]

Synonym: Rru_A0218

Alternate gene names: 83591558

Gene position: 270069-271034 (Clockwise)

Preceding gene: 83591557

Following gene: 83591559

Centisome position: 6.2

GC content: 65.22

Gene sequence:

>966_bases
ATGTGGACAGCCATGCATTTTCTGGACTTCGAGAAGCCGATCGCTGAATTGGAAGGCAAGATCGAGGAACTTCGCCACCT
CTCCGATGCCGATGGCATAAACATCGCCGAGGAGGTGGGGCGCCTGCAGCAGAAGGTGGATAAGCAGCTGCGCGCCGTCT
ATGCCAAGCTTACCCCCTGGCAAAAGGCGCTGGTCGCCCGCCATCCCGATCGGCCCCATTGCCTGGATTACGTCAAGGCG
CTGTTCACCGATTTCACGCCCTTGGCCGGCGATCGCCTGTATGGCGAGGATCACGCGGTGATCGGCGGGCTGGCGCGCTT
TCGCGGTCACCCGGTGGTCGTCATCGGCCAGGAAAAGGGCAGCGATACGGAAACCCGCCTGCGCCATAACTTCGGCATGG
CCCGGCCCGAGGGCTATCGCAAGGCCCAGCGCCTGATGACTCTGGCCGAGCGCTTCCATTTGCCGGTGCTGACCCTGATC
GATACCGCCGGGGCCTATCCGGGCGTCGGCGCCGAGGAGCGCGGTCAGGCCGAGGCCATCGCCCGCACCATCGAACGCGG
CCTTGATCTGCGCGTGCCCTTGATTTCCTGCGTGATCGGCGAGGGCGGCTCGGGCGGGGCCATCGCCATCGCCACCGGCA
ACGTCGTCTTGATGCTTGAACACGCCATCTATTCGGTGATTTCGCCGGAGGGCTGCGCCTCGATTCTGTGGCGCAGCGGC
GAGATGACCCAGCAGGCCGCCGAGGCCCTGCGGCTGACCGCCCAGGATCTGCTTGAGTTCAAGGTCATCGACGAGGCCAT
CCCCGAGCCTTTGGGCGGCGCCCATCGCGATCGCGCCATGACCTTCGAGCGGGTGGGCGAGGCCTTCAACCGCCATCTCG
AGCAGTTGATGCCCCAGGATGGCGGGGTGCTGCGCGCTCGGCGCCGCGATAAATTCCTGCAGATGGGCCGTCTCGAACTC
GCCTAA

Upstream 100 bases:

>100_bases
GTTTTGGCGAGCTTTGCGGTCTTTGCTTCGAGCGTCGGCTTTGACCGTCGGCTCTAACCGCCAGCTTTGACCGCCCGCTC
TGACCGCCAGCTCTGACCGA

Downstream 100 bases:

>100_bases
GGGCCTTTTTGCGCGTCCCGCTCCCTTTTGGCGACAGAATCGATCCCCCCGTGAAAAAAAGCCGGGGATGGCCGTGAACA
CGTCAGGGAAATCGGCCGTT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MWTAMHFLDFEKPIAELEGKIEELRHLSDADGINIAEEVGRLQQKVDKQLRAVYAKLTPWQKALVARHPDRPHCLDYVKA
LFTDFTPLAGDRLYGEDHAVIGGLARFRGHPVVVIGQEKGSDTETRLRHNFGMARPEGYRKAQRLMTLAERFHLPVLTLI
DTAGAYPGVGAEERGQAEAIARTIERGLDLRVPLISCVIGEGGSGGAIAIATGNVVLMLEHAIYSVISPEGCASILWRSG
EMTQQAAEALRLTAQDLLEFKVIDEAIPEPLGGAHRDRAMTFERVGEAFNRHLEQLMPQDGGVLRARRRDKFLQMGRLEL
A

Sequences:

>Translated_321_residues
MWTAMHFLDFEKPIAELEGKIEELRHLSDADGINIAEEVGRLQQKVDKQLRAVYAKLTPWQKALVARHPDRPHCLDYVKA
LFTDFTPLAGDRLYGEDHAVIGGLARFRGHPVVVIGQEKGSDTETRLRHNFGMARPEGYRKAQRLMTLAERFHLPVLTLI
DTAGAYPGVGAEERGQAEAIARTIERGLDLRVPLISCVIGEGGSGGAIAIATGNVVLMLEHAIYSVISPEGCASILWRSG
EMTQQAAEALRLTAQDLLEFKVIDEAIPEPLGGAHRDRAMTFERVGEAFNRHLEQLMPQDGGVLRARRRDKFLQMGRLEL
A
>Mature_321_residues
MWTAMHFLDFEKPIAELEGKIEELRHLSDADGINIAEEVGRLQQKVDKQLRAVYAKLTPWQKALVARHPDRPHCLDYVKA
LFTDFTPLAGDRLYGEDHAVIGGLARFRGHPVVVIGQEKGSDTETRLRHNFGMARPEGYRKAQRLMTLAERFHLPVLTLI
DTAGAYPGVGAEERGQAEAIARTIERGLDLRVPLISCVIGEGGSGGAIAIATGNVVLMLEHAIYSVISPEGCASILWRSG
EMTQQAAEALRLTAQDLLEFKVIDEAIPEPLGGAHRDRAMTFERVGEAFNRHLEQLMPQDGGVLRARRRDKFLQMGRLEL
A

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=277, Percent_Identity=57.4007220216607, Blast_Score=325, Evalue=2e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 35600; Mature: 35600

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWTAMHFLDFEKPIAELEGKIEELRHLSDADGINIAEEVGRLQQKVDKQLRAVYAKLTPW
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
QKALVARHPDRPHCLDYVKALFTDFTPLAGDRLYGEDHAVIGGLARFRGHPVVVIGQEKG
HHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCC
SDTETRLRHNFGMARPEGYRKAQRLMTLAERFHLPVLTLIDTAGAYPGVGAEERGQAEAI
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHH
ARTIERGLDLRVPLISCVIGEGGSGGAIAIATGNVVLMLEHAIYSVISPEGCASILWRSG
HHHHHHCCCCCCHHHHHEECCCCCCCEEEEECCCEEEHHHHHHHHHHCCCHHHHHHHCCC
EMTQQAAEALRLTAQDLLEFKVIDEAIPEPLGGAHRDRAMTFERVGEAFNRHLEQLMPQD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GGVLRARRRDKFLQMGRLELA
CCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MWTAMHFLDFEKPIAELEGKIEELRHLSDADGINIAEEVGRLQQKVDKQLRAVYAKLTPW
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
QKALVARHPDRPHCLDYVKALFTDFTPLAGDRLYGEDHAVIGGLARFRGHPVVVIGQEKG
HHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCC
SDTETRLRHNFGMARPEGYRKAQRLMTLAERFHLPVLTLIDTAGAYPGVGAEERGQAEAI
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHH
ARTIERGLDLRVPLISCVIGEGGSGGAIAIATGNVVLMLEHAIYSVISPEGCASILWRSG
HHHHHHCCCCCCHHHHHEECCCCCCCEEEEECCCEEEHHHHHHHHHHCCCHHHHHHHCCC
EMTQQAAEALRLTAQDLLEFKVIDEAIPEPLGGAHRDRAMTFERVGEAFNRHLEQLMPQD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GGVLRARRRDKFLQMGRLELA
CCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA