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The map label for this gene is cysS

Identifier: 83591300

GI number: 83591300

Start: 2589818

End: 2591248

Strand: Reverse

Name: cysS

Synonym: Moth_2484

Alternate gene names: 83591300

Gene position: 2591248-2589818 (Counterclockwise)

Preceding gene: 83591301

Following gene: 83591299

Centisome position: 98.57

GC content: 59.47

Gene sequence:

>1431_bases
ATGTATCTCTACAATACGCTGACGGGACGCAAGGAAGAGTTCACCCCAGTTGAACCGGGCCGGGTACGAATGTATGTCTG
TGGCCCGACAACCTACAACTATATCCATCTGGGTAACGCCCGGCCCATGGTGGTCTTCGATACCCTGCGACGTTACCTGG
AGTACCGGAACTATGATGTTTTATACGTACAGAACTTTACTGACATTGACGATAAGGTGATTAACCGGGCCCGGGAGGAG
CACCAGGCTCCCCTGGTCATTGCCGAACGGTATATTGAGGAATTCTTCAAGGACGCCGATGCCCTGAACGTCAAGCGGGC
TACCCTTTATCCCCGCGTTAGCCAGCATATCGACGCCATTATCGCGGCCATAGCCACCCTTGTTGAGCGTGGTTTCGCCT
ATGTCGCCGATGGGGATGTTTATTTCGAAGTCGAAAAGTTTCCTGCCTACGGCCGCCTGTCAAAGCGCACCCCGGGGGAG
ATGCGGGCGGGGGCACGGGTGGAGGTCAATACCAGCAAACGCAATCCCCTGGATTTCGCCCTGTGGAAGGCGGCCTGCCC
CGGCGAACCATCATGGGAAAGCCCATGGGGACCGGGGCGACCGGGATGGCATATTGAGTGCTCGACCATGGCCCTCAAAT
ACCTGGGCCCGGGCTTCGATATCCATGGAGGCGGCGCCGACCTCATTTTCCCTCATCACGAGAATGAAATTGCCCAGGCT
GAGGCCCAGACAGGGTGCACCTTTGCCCGCTTCTGGCTCCACAACGGCTTTATAACTGTAAACCAGGAAAAAATGTCCAA
GTCCAAGGGTAACTTCTTCCTGGTGCGGGACATCCTCAAACGTTTCCGGCCCCTGGCGGTGCGCCTCTACCTGCTGGCGA
CCCATTACCGCAGTCCCATTGACTTCGATGATGCGGGCCTGCTGGCGGCGGAGAGGGGCCTGGAGCGTCTGGAAAATACC
CGCCGTCTCCTGGGCGAAGCCCGCTGCCAGCTAACTGGCACCGGGGCGGAGACCACGGTGCCAGCAAGAACGTCGGCCCT
GGCCGGAAGGGCGGAAGAATTACGCCAGGAGTTCATCTCCGCCATGGACGACGACTTTAATACCGCCCGGGCCCTGGCAG
CCCTTTATGACCTGGCCCGGGAGATCAACTCCTACCTCAACGGGACAACAACCATCGACCCAGCGGCCCTGAGAACGGCG
GCTATAACCTTTGAGCAACTGGGGGGAGAAGTACTGGGCCTCTTTGGTCAGGCCCGGCAGCAGGTAGATGACGAACTCCT
AAGCGGGCTTATGGACCTCATCCTACAGGTTCGCCAGGAGGCCCGCCAGCGGCGCGACTGGGCCACGGCCGATACCATCC
GGGACCGGTTGAAGGAGCTGGGGATCGTCCTGGAGGATACCCCCCGCGGCCCGCGTTGGAAAAGGAGTTAA

Upstream 100 bases:

>100_bases
GAATTACCGGACCCGATGGCGGAGATGCTCCTCTGCCTGCAACGCCAGATCCAGCGTCTGGAGCAACGGGTAGAAGAACT
GGAGGCCGAAAAGGATTGGC

Downstream 100 bases:

>100_bases
AGGTTGTGGATTTCGTTGCCAACCTCTCTCCCCTGGCCCTGGCTTATGTCGGCGATGCCGTTTATGAATTATTAGTCCGG
GCCCACCTGGTAGGCCGGGG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MYLYNTLTGRKEEFTPVEPGRVRMYVCGPTTYNYIHLGNARPMVVFDTLRRYLEYRNYDVLYVQNFTDIDDKVINRAREE
HQAPLVIAERYIEEFFKDADALNVKRATLYPRVSQHIDAIIAAIATLVERGFAYVADGDVYFEVEKFPAYGRLSKRTPGE
MRAGARVEVNTSKRNPLDFALWKAACPGEPSWESPWGPGRPGWHIECSTMALKYLGPGFDIHGGGADLIFPHHENEIAQA
EAQTGCTFARFWLHNGFITVNQEKMSKSKGNFFLVRDILKRFRPLAVRLYLLATHYRSPIDFDDAGLLAAERGLERLENT
RRLLGEARCQLTGTGAETTVPARTSALAGRAEELRQEFISAMDDDFNTARALAALYDLAREINSYLNGTTTIDPAALRTA
AITFEQLGGEVLGLFGQARQQVDDELLSGLMDLILQVRQEARQRRDWATADTIRDRLKELGIVLEDTPRGPRWKRS

Sequences:

>Translated_476_residues
MYLYNTLTGRKEEFTPVEPGRVRMYVCGPTTYNYIHLGNARPMVVFDTLRRYLEYRNYDVLYVQNFTDIDDKVINRAREE
HQAPLVIAERYIEEFFKDADALNVKRATLYPRVSQHIDAIIAAIATLVERGFAYVADGDVYFEVEKFPAYGRLSKRTPGE
MRAGARVEVNTSKRNPLDFALWKAACPGEPSWESPWGPGRPGWHIECSTMALKYLGPGFDIHGGGADLIFPHHENEIAQA
EAQTGCTFARFWLHNGFITVNQEKMSKSKGNFFLVRDILKRFRPLAVRLYLLATHYRSPIDFDDAGLLAAERGLERLENT
RRLLGEARCQLTGTGAETTVPARTSALAGRAEELRQEFISAMDDDFNTARALAALYDLAREINSYLNGTTTIDPAALRTA
AITFEQLGGEVLGLFGQARQQVDDELLSGLMDLILQVRQEARQRRDWATADTIRDRLKELGIVLEDTPRGPRWKRS
>Mature_476_residues
MYLYNTLTGRKEEFTPVEPGRVRMYVCGPTTYNYIHLGNARPMVVFDTLRRYLEYRNYDVLYVQNFTDIDDKVINRAREE
HQAPLVIAERYIEEFFKDADALNVKRATLYPRVSQHIDAIIAAIATLVERGFAYVADGDVYFEVEKFPAYGRLSKRTPGE
MRAGARVEVNTSKRNPLDFALWKAACPGEPSWESPWGPGRPGWHIECSTMALKYLGPGFDIHGGGADLIFPHHENEIAQA
EAQTGCTFARFWLHNGFITVNQEKMSKSKGNFFLVRDILKRFRPLAVRLYLLATHYRSPIDFDDAGLLAAERGLERLENT
RRLLGEARCQLTGTGAETTVPARTSALAGRAEELRQEFISAMDDDFNTARALAALYDLAREINSYLNGTTTIDPAALRTA
AITFEQLGGEVLGLFGQARQQVDDELLSGLMDLILQVRQEARQRRDWATADTIRDRLKELGIVLEDTPRGPRWKRS

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI13375695, Length=482, Percent_Identity=38.7966804979253, Blast_Score=286, Evalue=4e-77,
Organism=Homo sapiens, GI10835051, Length=414, Percent_Identity=32.1256038647343, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI21269877, Length=414, Percent_Identity=32.1256038647343, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI62240992, Length=414, Percent_Identity=32.1256038647343, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI303304987, Length=414, Percent_Identity=32.1256038647343, Blast_Score=197, Evalue=2e-50,
Organism=Escherichia coli, GI1786737, Length=483, Percent_Identity=47.2049689440994, Blast_Score=408, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17509797, Length=439, Percent_Identity=31.2072892938497, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17509795, Length=439, Percent_Identity=31.2072892938497, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324082, Length=312, Percent_Identity=35.5769230769231, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI19922218, Length=502, Percent_Identity=32.4701195219124, Blast_Score=225, Evalue=4e-59,
Organism=Drosophila melanogaster, GI19922364, Length=353, Percent_Identity=34.8441926345609, Blast_Score=187, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYC_MOOTA (Q2RFM3)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_431309.1
- ProteinModelPortal:   Q2RFM3
- SMR:   Q2RFM3
- STRING:   Q2RFM3
- GeneID:   3831586
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_2484
- NMPDR:   fig|264732.9.peg.2515
- eggNOG:   COG0215
- HOGENOM:   HBG327651
- OMA:   DFDALNM
- PhylomeDB:   Q2RFM3
- BioCyc:   MTHE264732:MOTH_2484-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00041_B
- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10890
- PRINTS:   PR00983
- SMART:   SM00840
- TIGRFAMs:   TIGR00435

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.16

Molecular weight: Translated: 53968; Mature: 53968

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 267-267

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLYNTLTGRKEEFTPVEPGRVRMYVCGPTTYNYIHLGNARPMVVFDTLRRYLEYRNYDV
CEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCE
LYVQNFTDIDDKVINRAREEHQAPLVIAERYIEEFFKDADALNVKRATLYPRVSQHIDAI
EEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
IAAIATLVERGFAYVADGDVYFEVEKFPAYGRLSKRTPGEMRAGARVEVNTSKRNPLDFA
HHHHHHHHHCCCEEEECCEEEEEEECCCCCCCCCCCCCCHHCCCCEEEEECCCCCCCHHH
LWKAACPGEPSWESPWGPGRPGWHIECSTMALKYLGPGFDIHGGGADLIFPHHENEIAQA
HHHCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCEECCCCCCEEECCCCCHHHHH
EAQTGCTFARFWLHNGFITVNQEKMSKSKGNFFLVRDILKRFRPLAVRLYLLATHYRSPI
HHHCCCHHHHHHHHCCEEEEEHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
DFDDAGLLAAERGLERLENTRRLLGEARCQLTGTGAETTVPARTSALAGRAEELRQEFIS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHCHHHHHHHHHHH
AMDDDFNTARALAALYDLAREINSYLNGTTTIDPAALRTAAITFEQLGGEVLGLFGQARQ
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHH
QVDDELLSGLMDLILQVRQEARQRRDWATADTIRDRLKELGIVLEDTPRGPRWKRS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MYLYNTLTGRKEEFTPVEPGRVRMYVCGPTTYNYIHLGNARPMVVFDTLRRYLEYRNYDV
CEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCE
LYVQNFTDIDDKVINRAREEHQAPLVIAERYIEEFFKDADALNVKRATLYPRVSQHIDAI
EEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
IAAIATLVERGFAYVADGDVYFEVEKFPAYGRLSKRTPGEMRAGARVEVNTSKRNPLDFA
HHHHHHHHHCCCEEEECCEEEEEEECCCCCCCCCCCCCCHHCCCCEEEEECCCCCCCHHH
LWKAACPGEPSWESPWGPGRPGWHIECSTMALKYLGPGFDIHGGGADLIFPHHENEIAQA
HHHCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCEECCCCCCEEECCCCCHHHHH
EAQTGCTFARFWLHNGFITVNQEKMSKSKGNFFLVRDILKRFRPLAVRLYLLATHYRSPI
HHHCCCHHHHHHHHCCEEEEEHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
DFDDAGLLAAERGLERLENTRRLLGEARCQLTGTGAETTVPARTSALAGRAEELRQEFIS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHCHHHHHHHHHHH
AMDDDFNTARALAALYDLAREINSYLNGTTTIDPAALRTAAITFEQLGGEVLGLFGQARQ
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHH
QVDDELLSGLMDLILQVRQEARQRRDWATADTIRDRLKELGIVLEDTPRGPRWKRS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA