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The map label for this gene is comEB [H]

Identifier: 83591205

GI number: 83591205

Start: 2511374

End: 2511781

Strand: Reverse

Name: comEB [H]

Synonym: Moth_2389

Alternate gene names: 83591205

Gene position: 2511781-2511374 (Counterclockwise)

Preceding gene: 83591206

Following gene: 83591204

Centisome position: 95.55

GC content: 61.03

Gene sequence:

>408_bases
ATGCGTAAAGAGTGGGACGAATACTTTCTGGACATTGCCTTCCAGGTAGCCAGCCGGAGTACCTGCAACCGGCTGGCTGT
AGGTGCCGTGGTGGTAAAAGACAAGCGCATCAAAGGCACCGGCTATAATGGCGCCCCCCACGGCCTGCCCCACTGCCTGG
AGGTCGGCTGCCTCATGGAGGGCGAGCACTGCCTGCGTACCATCCACGCCGAGATCAACGCCCTCCTGGAGTGCTCGCCG
GAGGAACGGCAGGGGGCGACCATGTATGTCACCGACTACCCCTGCGAGAGGTGTGCCCTGGTCATCGTCCAGTCCGGCAT
CAAAAGACTCGTCTATGCCCGGCCCTATCATGTCAACCACGACTGGCTCCTGGAAGCAGGGATCGAAATCGTCCATCTGC
CCCGGTAA

Upstream 100 bases:

>100_bases
CAAACGGGACAGGTCTCACCGACCGGGGCCGGTCTCAATCATGTATCGGGTCTACTCCGGGCGCCGTGGGATCGGAAGCC
TGTACGCGAGGGATTAGTTT

Downstream 100 bases:

>100_bases
AGGGTAGTTGTCCTGACTATAAAAAATAGTGCCAACCCTGGCTGAAGAATGTTCGCATCCCTCCTCCGTTGTTATGCTTT
GTTATGGTATAATAAAGGGC

Product: CMP/dCMP deaminase, zinc-binding

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MRKEWDEYFLDIAFQVASRSTCNRLAVGAVVVKDKRIKGTGYNGAPHGLPHCLEVGCLMEGEHCLRTIHAEINALLECSP
EERQGATMYVTDYPCERCALVIVQSGIKRLVYARPYHVNHDWLLEAGIEIVHLPR

Sequences:

>Translated_135_residues
MRKEWDEYFLDIAFQVASRSTCNRLAVGAVVVKDKRIKGTGYNGAPHGLPHCLEVGCLMEGEHCLRTIHAEINALLECSP
EERQGATMYVTDYPCERCALVIVQSGIKRLVYARPYHVNHDWLLEAGIEIVHLPR
>Mature_135_residues
MRKEWDEYFLDIAFQVASRSTCNRLAVGAVVVKDKRIKGTGYNGAPHGLPHCLEVGCLMEGEHCLRTIHAEINALLECSP
EERQGATMYVTDYPCERCALVIVQSGIKRLVYARPYHVNHDWLLEAGIEIVHLPR

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=121, Percent_Identity=37.1900826446281, Blast_Score=77, Evalue=3e-15,
Organism=Homo sapiens, GI61742821, Length=121, Percent_Identity=37.1900826446281, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321938, Length=140, Percent_Identity=40, Blast_Score=97, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 15263; Mature: 15263

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKEWDEYFLDIAFQVASRSTCNRLAVGAVVVKDKRIKGTGYNGAPHGLPHCLEVGCLME
CCCHHHHHHHHHHHHHHCCCCCCHHHHEEEEEECCEECCCCCCCCCCCCCHHHHHHCCCC
GEHCLRTIHAEINALLECSPEERQGATMYVTDYPCERCALVIVQSGIKRLVYARPYHVNH
CHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEECCC
DWLLEAGIEIVHLPR
CHHHHCCCEEEECCC
>Mature Secondary Structure
MRKEWDEYFLDIAFQVASRSTCNRLAVGAVVVKDKRIKGTGYNGAPHGLPHCLEVGCLME
CCCHHHHHHHHHHHHHHCCCCCCHHHHEEEEEECCEECCCCCCCCCCCCCHHHHHHCCCC
GEHCLRTIHAEINALLECSPEERQGATMYVTDYPCERCALVIVQSGIKRLVYARPYHVNH
CHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEECCC
DWLLEAGIEIVHLPR
CHHHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]