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The map label for this gene is zwf [H]

Identifier: 83591123

GI number: 83591123

Start: 2417534

End: 2419048

Strand: Reverse

Name: zwf [H]

Synonym: Moth_2302

Alternate gene names: 83591123

Gene position: 2419048-2417534 (Counterclockwise)

Preceding gene: 83591124

Following gene: 83591122

Centisome position: 92.02

GC content: 57.03

Gene sequence:

>1515_bases
ATGGCCCCGGATCGGTTGGACAACAGCTTGCTGGTGATCTTTGGCGGCACGGGGGACCTCGCCCGGCGCAAGCTTTACCC
GGCTTTATTCAACCTTTTTGTCGATGGTTTCCTGCCGCCGGCTCTTGGGGTAATAGCTGTGGGCCGGTGCGGTTTTACCC
GGGATAGCTTCCGGCAGGAGATATTACTGCCGTCCCTGGAGACCTTTTCCCGCCGCGCCGCTTCCCTGGACGCCTATTTT
GAGCCCTTTGCCACCCGTTTGCACTATTTCCGAACCGACATTTATGACCCGGAGGGATATACCCGCCTGGGACAGTTCCT
GGTGGAACTGGAGGAGGCGGCGGGCTCCCGGGGCAACCGCATTTTTTACCTGGCCGTGGCCCCGGAACACTTTGGCCCCG
TAATCCGGAGCTTAAAGGAAACAGGCCTGGTACCAGCGCGGGGCTGGCAGCGGGTCGTTATTGAGAAACCCTTCGGCCAT
GACCTGCCTTCGGCGACAGAATTAAACCGCCAGCTGCGGGAGGCTTTCAGCGAAGAAGAGATTTACCGCATTGACCATTA
CCTGGGGAAAGAAATGATCCAGAACATCATGGTCATCCGCTTTGCCAATACTTTTTTTGAACCGGTCTGGAATAATAAAT
ATATCGACCACGTCCAAATTACTTCGGCGGAAACGGTGGGTGTGGAGAACCGGGGCGGCTACTACGACCGCGCCGGGGCG
CTGCGGGACATGGTCCAGAACCACCTCCTGCAACTGGTGACTTTGGTGGCCATGGAACCACCGGCCAGCCTGGCCACTGA
AGCTATTCGCGATGAAAAGGTAAAGGTGCTACGTTCTTTGAAACCCCTGGATGCGGCGGCAGTCAGCAAGAACGCCATCC
GCGGCCAGTACGGTGCCGGGGAGATAGATGGGCAGATGGTGCCGCCTTACCGCCAGGAAAAGGAAGTGGCCCCTGATTCC
ACGACGGAAACGTTTGTCGCTTTAAAGCTTTTCATAGATAACTTCCGCTGGGCCGGCGTGCCCTTTTACCTGCGTACGGG
CAAGCGCCTGCCGCTTAAAGTGACGGAAATTATCCTCCAGTTTAAATCCCTGCCGGATATCCTGTATTTTAAGGAATACG
GTGAATTACGCCCCAATCTCCTGGTCATCCGCGTCCAGCCCCTGGAAGGCGTCTACGTTCAGCTCAATGCCAAGCGGCCG
GGGAATAATAATTACATCGTACCCATCCGCCTGGATTTTTGCCAGAATTGTGAGGTGGGGGTTAATTCCCCCGAGGCCTA
TGAGCGCCTGCTTTATGATGTAATGCGGGGGGACCCTACCCTTTTCACCCGCTGGGATGAGGTGGAGGCGGCCTGGAAGT
TTGTCGATCCCATATCGGCCGCGTGGGCGGCTCAGGGGCAGCCGCAATTTCCCAATTACGCCGCCGGCCAGTGGGGGCCG
CCAGCGGCCCAGAGACTATTAATTTGCGATGCTCGCCGCTGGTGGGAGGAAAATGGAGCAGAATCGATTTCTTAA

Upstream 100 bases:

>100_bases
GTCCGCTGTTTTAGCGGGCTCCTTTTGATTCTATCAATAAAAAATAAAAACCAGGCCTGGAGCACAAAATAGTAGGGAAA
TTGGTGGAAAGGCGGATATT

Downstream 100 bases:

>100_bases
GGTGAAAAACTTGCGGATCTACGACATATCCATGCCCATATACCCCGGTATGCCGGTCTACAAAAACAGGGCGGAAAAGC
AACCGCAAACGGAAATAACT

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD; Vegetative protein 11; VEG11 [H]

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MAPDRLDNSLLVIFGGTGDLARRKLYPALFNLFVDGFLPPALGVIAVGRCGFTRDSFRQEILLPSLETFSRRAASLDAYF
EPFATRLHYFRTDIYDPEGYTRLGQFLVELEEAAGSRGNRIFYLAVAPEHFGPVIRSLKETGLVPARGWQRVVIEKPFGH
DLPSATELNRQLREAFSEEEIYRIDHYLGKEMIQNIMVIRFANTFFEPVWNNKYIDHVQITSAETVGVENRGGYYDRAGA
LRDMVQNHLLQLVTLVAMEPPASLATEAIRDEKVKVLRSLKPLDAAAVSKNAIRGQYGAGEIDGQMVPPYRQEKEVAPDS
TTETFVALKLFIDNFRWAGVPFYLRTGKRLPLKVTEIILQFKSLPDILYFKEYGELRPNLLVIRVQPLEGVYVQLNAKRP
GNNNYIVPIRLDFCQNCEVGVNSPEAYERLLYDVMRGDPTLFTRWDEVEAAWKFVDPISAAWAAQGQPQFPNYAAGQWGP
PAAQRLLICDARRWWEENGAESIS

Sequences:

>Translated_504_residues
MAPDRLDNSLLVIFGGTGDLARRKLYPALFNLFVDGFLPPALGVIAVGRCGFTRDSFRQEILLPSLETFSRRAASLDAYF
EPFATRLHYFRTDIYDPEGYTRLGQFLVELEEAAGSRGNRIFYLAVAPEHFGPVIRSLKETGLVPARGWQRVVIEKPFGH
DLPSATELNRQLREAFSEEEIYRIDHYLGKEMIQNIMVIRFANTFFEPVWNNKYIDHVQITSAETVGVENRGGYYDRAGA
LRDMVQNHLLQLVTLVAMEPPASLATEAIRDEKVKVLRSLKPLDAAAVSKNAIRGQYGAGEIDGQMVPPYRQEKEVAPDS
TTETFVALKLFIDNFRWAGVPFYLRTGKRLPLKVTEIILQFKSLPDILYFKEYGELRPNLLVIRVQPLEGVYVQLNAKRP
GNNNYIVPIRLDFCQNCEVGVNSPEAYERLLYDVMRGDPTLFTRWDEVEAAWKFVDPISAAWAAQGQPQFPNYAAGQWGP
PAAQRLLICDARRWWEENGAESIS
>Mature_503_residues
APDRLDNSLLVIFGGTGDLARRKLYPALFNLFVDGFLPPALGVIAVGRCGFTRDSFRQEILLPSLETFSRRAASLDAYFE
PFATRLHYFRTDIYDPEGYTRLGQFLVELEEAAGSRGNRIFYLAVAPEHFGPVIRSLKETGLVPARGWQRVVIEKPFGHD
LPSATELNRQLREAFSEEEIYRIDHYLGKEMIQNIMVIRFANTFFEPVWNNKYIDHVQITSAETVGVENRGGYYDRAGAL
RDMVQNHLLQLVTLVAMEPPASLATEAIRDEKVKVLRSLKPLDAAAVSKNAIRGQYGAGEIDGQMVPPYRQEKEVAPDST
TETFVALKLFIDNFRWAGVPFYLRTGKRLPLKVTEIILQFKSLPDILYFKEYGELRPNLLVIRVQPLEGVYVQLNAKRPG
NNNYIVPIRLDFCQNCEVGVNSPEAYERLLYDVMRGDPTLFTRWDEVEAAWKFVDPISAAWAAQGQPQFPNYAAGQWGPP
AAQRLLICDARRWWEENGAESIS

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI108773793, Length=483, Percent_Identity=38.9233954451346, Blast_Score=324, Evalue=1e-88,
Organism=Homo sapiens, GI109389365, Length=483, Percent_Identity=38.9233954451346, Blast_Score=324, Evalue=1e-88,
Organism=Homo sapiens, GI52145310, Length=497, Percent_Identity=30.5835010060362, Blast_Score=183, Evalue=3e-46,
Organism=Escherichia coli, GI1788158, Length=495, Percent_Identity=45.0505050505051, Blast_Score=410, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17538218, Length=482, Percent_Identity=40.4564315352697, Blast_Score=340, Evalue=7e-94,
Organism=Saccharomyces cerevisiae, GI6324088, Length=483, Percent_Identity=38.3022774327122, Blast_Score=318, Evalue=2e-87,
Organism=Drosophila melanogaster, GI24643350, Length=479, Percent_Identity=37.7870563674322, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24643352, Length=479, Percent_Identity=37.7870563674322, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI221513548, Length=497, Percent_Identity=30.3822937625755, Blast_Score=219, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 57221; Mature: 57090

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00069 G6P_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPDRLDNSLLVIFGGTGDLARRKLYPALFNLFVDGFLPPALGVIAVGRCGFTRDSFRQE
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHEECCCCCCHHHHHHH
ILLPSLETFSRRAASLDAYFEPFATRLHYFRTDIYDPEGYTRLGQFLVELEEAAGSRGNR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCE
IFYLAVAPEHFGPVIRSLKETGLVPARGWQRVVIEKPFGHDLPSATELNRQLREAFSEEE
EEEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCHHH
IYRIDHYLGKEMIQNIMVIRFANTFFEPVWNNKYIDHVQITSAETVGVENRGGYYDRAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEECCCCCCCCCHHHHH
LRDMVQNHLLQLVTLVAMEPPASLATEAIRDEKVKVLRSLKPLDAAAVSKNAIRGQYGAG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
EIDGQMVPPYRQEKEVAPDSTTETFVALKLFIDNFRWAGVPFYLRTGKRLPLKVTEIILQ
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHH
FKSLPDILYFKEYGELRPNLLVIRVQPLEGVYVQLNAKRPGNNNYIVPIRLDFCQNCEVG
HHCCCHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCC
VNSPEAYERLLYDVMRGDPTLFTRWDEVEAAWKFVDPISAAWAAQGQPQFPNYAAGQWGP
CCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCC
PAAQRLLICDARRWWEENGAESIS
HHHHHEEEHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
APDRLDNSLLVIFGGTGDLARRKLYPALFNLFVDGFLPPALGVIAVGRCGFTRDSFRQE
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHEECCCCCCHHHHHHH
ILLPSLETFSRRAASLDAYFEPFATRLHYFRTDIYDPEGYTRLGQFLVELEEAAGSRGNR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCE
IFYLAVAPEHFGPVIRSLKETGLVPARGWQRVVIEKPFGHDLPSATELNRQLREAFSEEE
EEEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCHHH
IYRIDHYLGKEMIQNIMVIRFANTFFEPVWNNKYIDHVQITSAETVGVENRGGYYDRAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEECCCCCCCCCHHHHH
LRDMVQNHLLQLVTLVAMEPPASLATEAIRDEKVKVLRSLKPLDAAAVSKNAIRGQYGAG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
EIDGQMVPPYRQEKEVAPDSTTETFVALKLFIDNFRWAGVPFYLRTGKRLPLKVTEIILQ
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHH
FKSLPDILYFKEYGELRPNLLVIRVQPLEGVYVQLNAKRPGNNNYIVPIRLDFCQNCEVG
HHCCCHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCC
VNSPEAYERLLYDVMRGDPTLFTRWDEVEAAWKFVDPISAAWAAQGQPQFPNYAAGQWGP
CCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCC
PAAQRLLICDARRWWEENGAESIS
HHHHHEEEHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9298659 [H]