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The map label for this gene is hycD [H]

Identifier: 83591013

GI number: 83591013

Start: 2288960

End: 2289901

Strand: Reverse

Name: hycD [H]

Synonym: Moth_2190

Alternate gene names: 83591013

Gene position: 2289901-2288960 (Counterclockwise)

Preceding gene: 83591014

Following gene: 83591012

Centisome position: 87.11

GC content: 54.35

Gene sequence:

>942_bases
ATGCCCGGTATCAAATTGTTCCTCGTCGGCCTGATGCAGGCCCTGTTAGTCCTGCTGGTAGCACCTCTTTTCGCGGGCCT
TACCCGTGTCTTAAGGGCAAGGCTGCATTCCAGGAAAGGGGCCAGTATTTTTCAGGACTACCGGGATATTTTTAAGCTCA
TAAAACGGCAAGAGGTGGTCCCCGCACAGGCCAGCTGGGTTTTTCGTTTTACCCCCTATGTAGTGATGGCAACCACGTTG
CTCATTGCCATGGTGATCCCGATTTTAACTCTTCAGTCGCCCCTGGGAATGGCCGGTGATTTGATCGCGGTTGTTTACCT
GTTCGCCCTGTTGCGCTTCTTTTTTGCCGTCGCAGGTCTGGATTCCGGTAGCGGGTTCGCCGGCATAGGAGCCAGCCGGG
AGATGGTGCTGGCCATTCTGGTGGAACCTACCATTATTTTGGTGTTATTCGTGCTTGCCCTTCTGACCGGCTCGACCGAT
CTGGGAGCCATCAGCCAGAAGGTGGCGTTCGGTTCGATATCATACTATAGACCGGCAGTCTGGCTTGGCATGCTGGCCTT
TGCTGTCGCCACTTTCATCGAGACCGGCAAGCTGCCGTTTGACCTGGCGGAAGCAGAACAGGAGCTTCAGGAAGGCCCCC
TCACGGAGTATTCCGGGCGCTCCCTGGCCATCTTGAAGTGGAGTTTGAGCATGAAGCAGGTTGTGGTAATCGCCCTGTTT
CTCGCCGTCTTCTTCCCCTTTGGGAGCGCCGCGGCGGTTAGCACTTCCTCTCTCCTGGTGTCTGCGGCTGCCTTTTTATT
GAAGGTTACTGGTTTTTACGTGATCGCTGCGTTGATGGAAAACAGCTCGGCCAGGTTGATTATTTATAAGGCCCCTGAAG
TGACCTGGCTGGCTTTCGGTATAGCCCTGCTGTCCTTCGTTTTCTACCTGGTCAATGTTTAA

Upstream 100 bases:

>100_bases
GCAGGCCTTCCAGATAGGGAACGTCAGGCTATATTGTCTCTATATAATCATAACCCTCGTAGTCCTGTTATTAGCGACGG
TTAGATAGGAGGAGAAAGAA

Downstream 100 bases:

>100_bases
GAGTGGAGGGGATAAGGTAGTGTCCGGCACTAGTGTAGTCAATACCCTGGCTGTACTGCTCATCCTGACCTCGATGCTGG
TGGTGGAAACCAGGAAGCTC

Product: respiratory-chain NADH dehydrogenase, subunit 1

Products: NA

Alternate protein names: FHL subunit 4; Hydrogenase 3 component D [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MPGIKLFLVGLMQALLVLLVAPLFAGLTRVLRARLHSRKGASIFQDYRDIFKLIKRQEVVPAQASWVFRFTPYVVMATTL
LIAMVIPILTLQSPLGMAGDLIAVVYLFALLRFFFAVAGLDSGSGFAGIGASREMVLAILVEPTIILVLFVLALLTGSTD
LGAISQKVAFGSISYYRPAVWLGMLAFAVATFIETGKLPFDLAEAEQELQEGPLTEYSGRSLAILKWSLSMKQVVVIALF
LAVFFPFGSAAAVSTSSLLVSAAAFLLKVTGFYVIAALMENSSARLIIYKAPEVTWLAFGIALLSFVFYLVNV

Sequences:

>Translated_313_residues
MPGIKLFLVGLMQALLVLLVAPLFAGLTRVLRARLHSRKGASIFQDYRDIFKLIKRQEVVPAQASWVFRFTPYVVMATTL
LIAMVIPILTLQSPLGMAGDLIAVVYLFALLRFFFAVAGLDSGSGFAGIGASREMVLAILVEPTIILVLFVLALLTGSTD
LGAISQKVAFGSISYYRPAVWLGMLAFAVATFIETGKLPFDLAEAEQELQEGPLTEYSGRSLAILKWSLSMKQVVVIALF
LAVFFPFGSAAAVSTSSLLVSAAAFLLKVTGFYVIAALMENSSARLIIYKAPEVTWLAFGIALLSFVFYLVNV
>Mature_312_residues
PGIKLFLVGLMQALLVLLVAPLFAGLTRVLRARLHSRKGASIFQDYRDIFKLIKRQEVVPAQASWVFRFTPYVVMATTLL
IAMVIPILTLQSPLGMAGDLIAVVYLFALLRFFFAVAGLDSGSGFAGIGASREMVLAILVEPTIILVLFVLALLTGSTDL
GAISQKVAFGSISYYRPAVWLGMLAFAVATFIETGKLPFDLAEAEQELQEGPLTEYSGRSLAILKWSLSMKQVVVIALFL
AVFFPFGSAAAVSTSSLLVSAAAFLLKVTGFYVIAALMENSSARLIIYKAPEVTWLAFGIALLSFVFYLVNV

Specific function: Hydrogen metabolism; FHL pathway. [C]

COG id: COG0650

COG function: function code C; Formate hydrogenlyase subunit 4

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1789077, Length=297, Percent_Identity=50.8417508417508, Blast_Score=295, Evalue=2e-81,
Organism=Escherichia coli, GI87082115, Length=308, Percent_Identity=51.6233766233766, Blast_Score=280, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: NA

Molecular weight: Translated: 33893; Mature: 33762

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGIKLFLVGLMQALLVLLVAPLFAGLTRVLRARLHSRKGASIFQDYRDIFKLIKRQEVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
PAQASWVFRFTPYVVMATTLLIAMVIPILTLQSPLGMAGDLIAVVYLFALLRFFFAVAGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
DSGSGFAGIGASREMVLAILVEPTIILVLFVLALLTGSTDLGAISQKVAFGSISYYRPAV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHH
WLGMLAFAVATFIETGKLPFDLAEAEQELQEGPLTEYSGRSLAILKWSLSMKQVVVIALF
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHHH
LAVFFPFGSAAAVSTSSLLVSAAAFLLKVTGFYVIAALMENSSARLIIYKAPEVTWLAFG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
IALLSFVFYLVNV
HHHHHHHHHHHCC
>Mature Secondary Structure 
PGIKLFLVGLMQALLVLLVAPLFAGLTRVLRARLHSRKGASIFQDYRDIFKLIKRQEVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
PAQASWVFRFTPYVVMATTLLIAMVIPILTLQSPLGMAGDLIAVVYLFALLRFFFAVAGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
DSGSGFAGIGASREMVLAILVEPTIILVLFVLALLTGSTDLGAISQKVAFGSISYYRPAV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHH
WLGMLAFAVATFIETGKLPFDLAEAEQELQEGPLTEYSGRSLAILKWSLSMKQVVVIALF
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHHH
LAVFFPFGSAAAVSTSSLLVSAAAFLLKVTGFYVIAALMENSSARLIIYKAPEVTWLAFG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
IALLSFVFYLVNV
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2187144; 9278503 [H]