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The map label for this gene is moaC [H]

Identifier: 83590960

GI number: 83590960

Start: 2231778

End: 2232281

Strand: Reverse

Name: moaC [H]

Synonym: Moth_2134

Alternate gene names: 83590960

Gene position: 2232281-2231778 (Counterclockwise)

Preceding gene: 83590961

Following gene: 83590959

Centisome position: 84.92

GC content: 61.9

Gene sequence:

>504_bases
ATGAGCAATCCTCTTACCCACCTCGATACAAAAGGGCAGGCGCGCATGGTTGACGTCGGCGCCAAGGCAGTCACCGAAAG
GATGGCTGTCGCCAGGGGTCGGGTGCTCATGAGCAAGGATACCCTGAGCCTGATCATAGAGGGTGGGATGCCCAAGGGTG
ACGTCCTGGCCGTGGCGCGGGTGGCCGGCATTATGGCCGCCAAACAGACAGGGAGCCTGATCCCCCTCTGCCACCCCCTC
CCGGTGAGCGCTGTCAGCGTCGATTTTCGCCCCGACCCGGAGGCCGGGGCTGTCGAAATCGAAGCCCGGGTGAAGACGGT
CAGCCAGACGGGGGTGGAGATGGAAGCCCTGACGGCAGTGAGCGTGGCCGCCCTGACTATCTATGACATGTGCAAAGCCG
TTGAGCGGGGTATGGTTATCGATAAAATCAGGCTAATCGAAAAGACTGGTGGCCGCAGCGGCCACTTCTTGCGGGAAGGG
GAGCAGCCATGGGCAGAATCGTAG

Upstream 100 bases:

>100_bases
AGCCCGCCGAACACCACATGGAGAACGGCTGGCGCCAGCCCCGGGCCATGTCCCAGATAGGCGGCTGAAACGTGGGAAGT
GAGAGGGAGGAACTTCCGCT

Downstream 100 bases:

>100_bases
CCGTCTGTACCTCGGCCAACAAGGGTGAGCGAAAAAAGAATATCGGCCGGGGGATGCTCATTGCCAACTACGGCCTTAAG
GGGGACGCCCACGCCGGGCC

Product: GTP cyclohydrolase subunit MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MSNPLTHLDTKGQARMVDVGAKAVTERMAVARGRVLMSKDTLSLIIEGGMPKGDVLAVARVAGIMAAKQTGSLIPLCHPL
PVSAVSVDFRPDPEAGAVEIEARVKTVSQTGVEMEALTAVSVAALTIYDMCKAVERGMVIDKIRLIEKTGGRSGHFLREG
EQPWAES

Sequences:

>Translated_167_residues
MSNPLTHLDTKGQARMVDVGAKAVTERMAVARGRVLMSKDTLSLIIEGGMPKGDVLAVARVAGIMAAKQTGSLIPLCHPL
PVSAVSVDFRPDPEAGAVEIEARVKTVSQTGVEMEALTAVSVAALTIYDMCKAVERGMVIDKIRLIEKTGGRSGHFLREG
EQPWAES
>Mature_166_residues
SNPLTHLDTKGQARMVDVGAKAVTERMAVARGRVLMSKDTLSLIIEGGMPKGDVLAVARVAGIMAAKQTGSLIPLCHPLP
VSAVSVDFRPDPEAGAVEIEARVKTVSQTGVEMEALTAVSVAALTIYDMCKAVERGMVIDKIRLIEKTGGRSGHFLREGE
QPWAES

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=159, Percent_Identity=55.9748427672956, Blast_Score=172, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI32566331, Length=162, Percent_Identity=41.358024691358, Blast_Score=139, Evalue=7e-34,
Organism=Drosophila melanogaster, GI28574490, Length=158, Percent_Identity=51.8987341772152, Blast_Score=149, Evalue=6e-37,
Organism=Drosophila melanogaster, GI28574492, Length=147, Percent_Identity=51.7006802721088, Blast_Score=137, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17738; Mature: 17607

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPLTHLDTKGQARMVDVGAKAVTERMAVARGRVLMSKDTLSLIIEGGMPKGDVLAVAR
CCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCEEEECCCEEEEEECCCCCCHHHHHHH
VAGIMAAKQTGSLIPLCHPLPVSAVSVDFRPDPEAGAVEIEARVKTVSQTGVEMEALTAV
HHHHHHHHCCCCCCEECCCCCCCEEEEECCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHH
SVAALTIYDMCKAVERGMVIDKIRLIEKTGGRSGHFLREGEQPWAES
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SNPLTHLDTKGQARMVDVGAKAVTERMAVARGRVLMSKDTLSLIIEGGMPKGDVLAVAR
CCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCEEEECCCEEEEEECCCCCCHHHHHHH
VAGIMAAKQTGSLIPLCHPLPVSAVSVDFRPDPEAGAVEIEARVKTVSQTGVEMEALTAV
HHHHHHHHCCCCCCEECCCCCCCEEEEECCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHH
SVAALTIYDMCKAVERGMVIDKIRLIEKTGGRSGHFLREGEQPWAES
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA