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The map label for this gene is xylB [H]

Identifier: 83590855

GI number: 83590855

Start: 2113215

End: 2114744

Strand: Reverse

Name: xylB [H]

Synonym: Moth_2025

Alternate gene names: 83590855

Gene position: 2114744-2113215 (Counterclockwise)

Preceding gene: 83590856

Following gene: 83590854

Centisome position: 80.45

GC content: 60.78

Gene sequence:

>1530_bases
ATGCCGTATCTTCTCGGGATTGATATCGGTACTTCGGGCACCAAAGCCCTCCTGGTGGAGGAAACCGGCAGGGTTGTAGC
TTCTGCCTATAAAGAGTATCCTTTGAGCCAGCCCCGGCCGGGGTGGGCCGAGCAGGATCCGGAGGAGTGGTGGCGGGCCG
TGGTGGAGGCGGCCCGGGAAGTCCTCGCCCGGAGCGGTCTGGCAGGCGGCGATGTTGCCGGCGTGGGTCTTTCCGGCCAG
ATGCATGGGGCGGTAGTTCTTGACGCTAATTACAGGGTTTTACGGCCGGCTATCCTCTGGTGCGACCAGCGAACGGGAGC
AGAGTGCGCCTGGATGTACGAAGAAATAGGGCAAGAAAAACTCTACCGGTGGACGGGAAACCCGGTCCTGCCAGGCTTTA
CGGCGCCCAAGCTGGTCTGGCTTAAGCGCCATGAACCGGAAACCTATAGCAGGATACGCCATGTCCTGTTGCCCAAGGAT
TATATTCGCTTCCGCCTGACAGGGGAACTGGCTACCGAGGTATCTGACGCTTCCGGAACCCTGCTCCTGGATGTGACCCA
CCGGTGCTGGTCCGGTGAGATACTGGCCGCCATGGGCCTCCCGGAGGAATGGCTGCCCCGGGTATATGAATCGCCGGAAG
TAACCGGACGCATAACCCCTGAGGCCGCTGCCCTCACCGGTCTAATGGCGGGAACGCCGGTGGTAGGCGGAGGCGGCGAC
CAGGCCGCCGGGGCCATAGGTACAGGAGTCGTAGTAGAAGGAATTATTTCCACTGCCCTGGGTACGTCGGGTGTAGTTTT
CGCCATGACCGATCGGCCCCACACCCAGCCGGGGAGCGCCCTGCATTCCTTCTGCCATGCCGTGCCGGGCAAGTGGCACC
TGATGGGTGTGATGCTGGCCGCCGGGGGATCCTTGCAGTGGTTCCGTAATCAACTCGGTAGCGAGGAGGTGCGGGAAGCC
GCCGTAAAGAATATCGATCCCTACGAAATGTTGACAGAACAGGCGGCTGAGGTCGGCACCGGCGCAGGAGGATTGCTGTT
CCTCCCTTACCTTCTGGGAGAAAGGACGCCCTACCCTGATCCGGCGGCTAGGGGCGCTTTTATCGGCCTGACCATGCGTC
ACCGGAAAGGCCATCTGGTACGGGCCGTCATGGAGGGGGTTGCTTTCGGCCTGAGGGACTCCTTGGAGCTGCTCCGGCAG
GCCGGGGTGAAAGTAGAGGAAATCCGGGTTTCAGGCGGCGGCGCCAGAAGCCCCCTGTGGCGCCATATCCTGGCCAGTAC
CTTTAAGTATCCAATAACCACGGTGAACAGCACCGACGGTCCGGCCTTCGGCGCCGCCCTGCTGGCTGGCGTGGGGGCGG
GCATTTATCCTTCCGTCGAGGAAGCCTGCAGGTTGACCATTAAAGTGACCAGCCGGGTGGAACCGATAGCACCCGAAACA
GATGCCTACGATAGGCTGTATGAAATATATAAATCCCTTTATCCTCTCCTGCGCGACACGATGCACGATCTGACAAAATT
TACGGAGTGA

Upstream 100 bases:

>100_bases
CTTAAGCCTCCAAGGAGTATAATCCGCCAGTAATTTTAAAACAGTTACCGGACGACGACTTCCATTTCAGCATAGACGTT
TTCAGAAGGGAAAAGGAATT

Downstream 100 bases:

>100_bases
AAACGATTTGCCAAATATCTCTGATGTTGCCAGAAGAGCCGGAGTATCACGAACTACGGTATCCAGGGTCCTCAACGGGA
AAGACGACGTCAACGAAGAA

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MPYLLGIDIGTSGTKALLVEETGRVVASAYKEYPLSQPRPGWAEQDPEEWWRAVVEAAREVLARSGLAGGDVAGVGLSGQ
MHGAVVLDANYRVLRPAILWCDQRTGAECAWMYEEIGQEKLYRWTGNPVLPGFTAPKLVWLKRHEPETYSRIRHVLLPKD
YIRFRLTGELATEVSDASGTLLLDVTHRCWSGEILAAMGLPEEWLPRVYESPEVTGRITPEAAALTGLMAGTPVVGGGGD
QAAGAIGTGVVVEGIISTALGTSGVVFAMTDRPHTQPGSALHSFCHAVPGKWHLMGVMLAAGGSLQWFRNQLGSEEVREA
AVKNIDPYEMLTEQAAEVGTGAGGLLFLPYLLGERTPYPDPAARGAFIGLTMRHRKGHLVRAVMEGVAFGLRDSLELLRQ
AGVKVEEIRVSGGGARSPLWRHILASTFKYPITTVNSTDGPAFGAALLAGVGAGIYPSVEEACRLTIKVTSRVEPIAPET
DAYDRLYEIYKSLYPLLRDTMHDLTKFTE

Sequences:

>Translated_509_residues
MPYLLGIDIGTSGTKALLVEETGRVVASAYKEYPLSQPRPGWAEQDPEEWWRAVVEAAREVLARSGLAGGDVAGVGLSGQ
MHGAVVLDANYRVLRPAILWCDQRTGAECAWMYEEIGQEKLYRWTGNPVLPGFTAPKLVWLKRHEPETYSRIRHVLLPKD
YIRFRLTGELATEVSDASGTLLLDVTHRCWSGEILAAMGLPEEWLPRVYESPEVTGRITPEAAALTGLMAGTPVVGGGGD
QAAGAIGTGVVVEGIISTALGTSGVVFAMTDRPHTQPGSALHSFCHAVPGKWHLMGVMLAAGGSLQWFRNQLGSEEVREA
AVKNIDPYEMLTEQAAEVGTGAGGLLFLPYLLGERTPYPDPAARGAFIGLTMRHRKGHLVRAVMEGVAFGLRDSLELLRQ
AGVKVEEIRVSGGGARSPLWRHILASTFKYPITTVNSTDGPAFGAALLAGVGAGIYPSVEEACRLTIKVTSRVEPIAPET
DAYDRLYEIYKSLYPLLRDTMHDLTKFTE
>Mature_508_residues
PYLLGIDIGTSGTKALLVEETGRVVASAYKEYPLSQPRPGWAEQDPEEWWRAVVEAAREVLARSGLAGGDVAGVGLSGQM
HGAVVLDANYRVLRPAILWCDQRTGAECAWMYEEIGQEKLYRWTGNPVLPGFTAPKLVWLKRHEPETYSRIRHVLLPKDY
IRFRLTGELATEVSDASGTLLLDVTHRCWSGEILAAMGLPEEWLPRVYESPEVTGRITPEAAALTGLMAGTPVVGGGGDQ
AAGAIGTGVVVEGIISTALGTSGVVFAMTDRPHTQPGSALHSFCHAVPGKWHLMGVMLAAGGSLQWFRNQLGSEEVREAA
VKNIDPYEMLTEQAAEVGTGAGGLLFLPYLLGERTPYPDPAARGAFIGLTMRHRKGHLVRAVMEGVAFGLRDSLELLRQA
GVKVEEIRVSGGGARSPLWRHILASTFKYPITTVNSTDGPAFGAALLAGVGAGIYPSVEEACRLTIKVTSRVEPIAPETD
AYDRLYEIYKSLYPLLRDTMHDLTKFTE

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=453, Percent_Identity=27.5938189845475, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI189409120, Length=453, Percent_Identity=27.5938189845475, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI4504007, Length=453, Percent_Identity=27.5938189845475, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI41393575, Length=445, Percent_Identity=28.0898876404494, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI164663828, Length=537, Percent_Identity=23.8361266294227, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI164663830, Length=561, Percent_Identity=22.8163992869875, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI18860918, Length=486, Percent_Identity=24.0740740740741, Blast_Score=90, Evalue=5e-18,
Organism=Escherichia coli, GI1789987, Length=500, Percent_Identity=43.8, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI1790005, Length=504, Percent_Identity=32.5396825396825, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1787789, Length=502, Percent_Identity=28.8844621513944, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1790361, Length=473, Percent_Identity=26.4270613107822, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1789168, Length=465, Percent_Identity=27.0967741935484, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI1789138, Length=499, Percent_Identity=24.4488977955912, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1790338, Length=163, Percent_Identity=28.2208588957055, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17535599, Length=454, Percent_Identity=29.0748898678414, Blast_Score=149, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6320314, Length=574, Percent_Identity=23.8675958188153, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6321633, Length=398, Percent_Identity=23.6180904522613, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24655555, Length=447, Percent_Identity=28.8590604026846, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24655560, Length=447, Percent_Identity=28.8590604026846, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24655570, Length=447, Percent_Identity=28.8590604026846, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24655574, Length=447, Percent_Identity=28.8590604026846, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24655565, Length=447, Percent_Identity=28.8590604026846, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24657106, Length=536, Percent_Identity=25.1865671641791, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24657102, Length=536, Percent_Identity=25.1865671641791, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17864214, Length=512, Percent_Identity=24.4140625, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21357867, Length=549, Percent_Identity=22.2222222222222, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24654573, Length=439, Percent_Identity=24.6013667425968, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24656367, Length=539, Percent_Identity=22.2634508348794, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19922058, Length=542, Percent_Identity=22.8782287822878, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24652871, Length=500, Percent_Identity=22.4, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356323, Length=410, Percent_Identity=25.3658536585366, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24656372, Length=354, Percent_Identity=22.316384180791, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 55103; Mature: 54972

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYLLGIDIGTSGTKALLVEETGRVVASAYKEYPLSQPRPGWAEQDPEEWWRAVVEAARE
CCEEEEEEECCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VLARSGLAGGDVAGVGLSGQMHGAVVLDANYRVLRPAILWCDQRTGAECAWMYEEIGQEK
HHHHCCCCCCCEECCCCCCCCCEEEEEECCCHHHHHHHHEECCCCCCHHHHHHHHHCHHH
LYRWTGNPVLPGFTAPKLVWLKRHEPETYSRIRHVLLPKDYIRFRLTGELATEVSDASGT
HEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHEEEEEECHHHHHCCCCCCE
LLLDVTHRCWSGEILAAMGLPEEWLPRVYESPEVTGRITPEAAALTGLMAGTPVVGGGGD
EEEEECCCCCCCCEEEECCCCHHHHHHHHCCCCCCEEECCHHHHHHHHHCCCCEECCCCC
QAAGAIGTGVVVEGIISTALGTSGVVFAMTDRPHTQPGSALHSFCHAVPGKWHLMGVMLA
CCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHH
AGGSLQWFRNQLGSEEVREAAVKNIDPYEMLTEQAAEVGTGAGGLLFLPYLLGERTPYPD
CCCCHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
PAARGAFIGLTMRHRKGHLVRAVMEGVAFGLRDSLELLRQAGVKVEEIRVSGGGARSPLW
CCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHH
RHILASTFKYPITTVNSTDGPAFGAALLAGVGAGIYPSVEEACRLTIKVTSRVEPIAPET
HHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHEEEEEEECCCCCCCCCC
DAYDRLYEIYKSLYPLLRDTMHDLTKFTE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PYLLGIDIGTSGTKALLVEETGRVVASAYKEYPLSQPRPGWAEQDPEEWWRAVVEAARE
CEEEEEEECCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VLARSGLAGGDVAGVGLSGQMHGAVVLDANYRVLRPAILWCDQRTGAECAWMYEEIGQEK
HHHHCCCCCCCEECCCCCCCCCEEEEEECCCHHHHHHHHEECCCCCCHHHHHHHHHCHHH
LYRWTGNPVLPGFTAPKLVWLKRHEPETYSRIRHVLLPKDYIRFRLTGELATEVSDASGT
HEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHEEEEEECHHHHHCCCCCCE
LLLDVTHRCWSGEILAAMGLPEEWLPRVYESPEVTGRITPEAAALTGLMAGTPVVGGGGD
EEEEECCCCCCCCEEEECCCCHHHHHHHHCCCCCCEEECCHHHHHHHHHCCCCEECCCCC
QAAGAIGTGVVVEGIISTALGTSGVVFAMTDRPHTQPGSALHSFCHAVPGKWHLMGVMLA
CCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHH
AGGSLQWFRNQLGSEEVREAAVKNIDPYEMLTEQAAEVGTGAGGLLFLPYLLGERTPYPD
CCCCHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
PAARGAFIGLTMRHRKGHLVRAVMEGVAFGLRDSLELLRQAGVKVEEIRVSGGGARSPLW
CCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHH
RHILASTFKYPITTVNSTDGPAFGAALLAGVGAGIYPSVEEACRLTIKVTSRVEPIAPET
HHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHEEEEEEECCCCCCCCCC
DAYDRLYEIYKSLYPLLRDTMHDLTKFTE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]