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The map label for this gene is thrC [H]

Identifier: 83590828

GI number: 83590828

Start: 2082267

End: 2083511

Strand: Reverse

Name: thrC [H]

Synonym: Moth_1998

Alternate gene names: 83590828

Gene position: 2083511-2082267 (Counterclockwise)

Preceding gene: 83590829

Following gene: 83590827

Centisome position: 79.26

GC content: 60.0

Gene sequence:

>1245_bases
ATGAGCAATATAACCCAACTACGCTGTATAAACTGCAGCCGTACCTATCAACCCCGGCCCGGCTTTTATACCTGCCCCAT
CTGCGGGTCGACGGACGGCATCCTGGATGTCGAATACGATTACGATTATATAAACAAATCCATCTCCAGGCAGAGCCTGG
CCAGCAACCGGGAACATTCCCTCTGGCGTTACCGTCCCTTCTTGCCGGTGGCCCAGGAGGGACCGCTGCCCCCTCTGCGG
GTGGGTTGGAGCCCCCTGTACCGGGCCCGGCGCCTGGGGGACGAACTGGGGTTGAAAGAGCTATATATCAAGGACGATGG
GATTAATCCCACGGGGTCTTTAAAAGACAGGCCTTCGGCCGTGGCGGTGGCCCGAGCCCTGGCCGAAGGAGCTAAGGTGG
TCGCCTGCTCTTCAACCGGCAACGCTGCTTCCTCCCTGGCGGGGGCAGCAGCTTCCGTGGGCCTGAAGGCGGTAATCTTT
GTACCGGGACGGGCACCGCAAGGGAAGGTAGCCCAACTCTTGATTTTCGGGGCCACCGTTATCAGTGTTCAGGGATCCTA
TGAGGATGCCTTCAAGCTTTCGGCGGCGGCCATAGCCGAGCACGGCTGGTACAACCGCAATGCCGCCATTAACCCTTATC
TGGTAGAAGGCAAAAAGACAGTTTGCCTGGAAGTGGCGGAACAGCTAAACTGGGAGGTACCCGACTGGGTGGTCCTTTCC
GTGGGCGACGGTTGTACCATGGCCGGTGCCTGGAAGGCCTGGGTGGACCTGAAAAAGGCCGGTTGGATTGACAAACTGCC
GCGGATGCTGGGGGTCCAGGCCGAGGGTTGCTGCCCCATTACCAGGGCCTTCCGGGAGGGAACCAGGGTAAAACCCATGC
CCGAAAATACCCTGGCGGACAGCATCGCCGTCGGCGTGCCCCGCAATCCAGAAAAGGCTCTGCGGGCCGTAAGGGATTCC
GGGGGTACGATGATCAACGTCAGCGATGAAGAAATCCTTGCAGCCATGCGCACCCTGGGGCGGACCAGCGGCATCTTCGG
CGAACCTGCCGGTGCAGCCGGGACCGCCGGCCTTATCAAAGCCGTCCAGGAAGGAATAATTAAATCCGGAGATAAGGTGG
TCGTCCTGGTAACAGGCAACGGCCTCAAGGATGTGGCCAATGCCATCAAAGCGGCCGGAGAGCCTATCCGGGTGGAGCCC
TCCCTGGAGGCCTTAAAGGAAGCCCTGGCTCGGTACGGGAAATGA

Upstream 100 bases:

>100_bases
GAAGATAACGTTGTTACGTGGCAGCGTGGGATAGAACCCTCCGCGGACAGTAGAGATACCTTGTGGGAAGAGAGAGTTTT
TACGGGAGAGATGACTCAAG

Downstream 100 bases:

>100_bases
ACCGCGGCCGGGAAGAGACAGGTAGGGCGGATATATAATGTAGATTACAAAGGAGGCGCCGGAGAAAATGGATCTCTTGC
TGAAGGGCGGCTGGGTTGTT

Product: L-threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSNITQLRCINCSRTYQPRPGFYTCPICGSTDGILDVEYDYDYINKSISRQSLASNREHSLWRYRPFLPVAQEGPLPPLR
VGWSPLYRARRLGDELGLKELYIKDDGINPTGSLKDRPSAVAVARALAEGAKVVACSSTGNAASSLAGAAASVGLKAVIF
VPGRAPQGKVAQLLIFGATVISVQGSYEDAFKLSAAAIAEHGWYNRNAAINPYLVEGKKTVCLEVAEQLNWEVPDWVVLS
VGDGCTMAGAWKAWVDLKKAGWIDKLPRMLGVQAEGCCPITRAFREGTRVKPMPENTLADSIAVGVPRNPEKALRAVRDS
GGTMINVSDEEILAAMRTLGRTSGIFGEPAGAAGTAGLIKAVQEGIIKSGDKVVVLVTGNGLKDVANAIKAAGEPIRVEP
SLEALKEALARYGK

Sequences:

>Translated_414_residues
MSNITQLRCINCSRTYQPRPGFYTCPICGSTDGILDVEYDYDYINKSISRQSLASNREHSLWRYRPFLPVAQEGPLPPLR
VGWSPLYRARRLGDELGLKELYIKDDGINPTGSLKDRPSAVAVARALAEGAKVVACSSTGNAASSLAGAAASVGLKAVIF
VPGRAPQGKVAQLLIFGATVISVQGSYEDAFKLSAAAIAEHGWYNRNAAINPYLVEGKKTVCLEVAEQLNWEVPDWVVLS
VGDGCTMAGAWKAWVDLKKAGWIDKLPRMLGVQAEGCCPITRAFREGTRVKPMPENTLADSIAVGVPRNPEKALRAVRDS
GGTMINVSDEEILAAMRTLGRTSGIFGEPAGAAGTAGLIKAVQEGIIKSGDKVVVLVTGNGLKDVANAIKAAGEPIRVEP
SLEALKEALARYGK
>Mature_413_residues
SNITQLRCINCSRTYQPRPGFYTCPICGSTDGILDVEYDYDYINKSISRQSLASNREHSLWRYRPFLPVAQEGPLPPLRV
GWSPLYRARRLGDELGLKELYIKDDGINPTGSLKDRPSAVAVARALAEGAKVVACSSTGNAASSLAGAAASVGLKAVIFV
PGRAPQGKVAQLLIFGATVISVQGSYEDAFKLSAAAIAEHGWYNRNAAINPYLVEGKKTVCLEVAEQLNWEVPDWVVLSV
GDGCTMAGAWKAWVDLKKAGWIDKLPRMLGVQAEGCCPITRAFREGTRVKPMPENTLADSIAVGVPRNPEKALRAVRDSG
GTMINVSDEEILAAMRTLGRTSGIFGEPAGAAGTAGLIKAVQEGIIKSGDKVVVLVTGNGLKDVANAIKAAGEPIRVEPS
LEALKEALARYGK

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789235, Length=387, Percent_Identity=24.2894056847545, Blast_Score=63, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322631, Length=304, Percent_Identity=26.9736842105263, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 44167; Mature: 44036

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNITQLRCINCSRTYQPRPGFYTCPICGSTDGILDVEYDYDYINKSISRQSLASNREHS
CCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCC
LWRYRPFLPVAQEGPLPPLRVGWSPLYRARRLGDELGLKELYIKDDGINPTGSLKDRPSA
CEEECCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHH
VAVARALAEGAKVVACSSTGNAASSLAGAAASVGLKAVIFVPGRAPQGKVAQLLIFGATV
HHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHEEEEEEE
ISVQGSYEDAFKLSAAAIAEHGWYNRNAAINPYLVEGKKTVCLEVAEQLNWEVPDWVVLS
EEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCEEEEE
VGDGCTMAGAWKAWVDLKKAGWIDKLPRMLGVQAEGCCPITRAFREGTRVKPMPENTLAD
ECCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCHHHH
SIAVGVPRNPEKALRAVRDSGGTMINVSDEEILAAMRTLGRTSGIFGEPAGAAGTAGLIK
HEEECCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
AVQEGIIKSGDKVVVLVTGNGLKDVANAIKAAGEPIRVEPSLEALKEALARYGK
HHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNITQLRCINCSRTYQPRPGFYTCPICGSTDGILDVEYDYDYINKSISRQSLASNREHS
CCCCEEEEECCCCCCCCCCCEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCC
LWRYRPFLPVAQEGPLPPLRVGWSPLYRARRLGDELGLKELYIKDDGINPTGSLKDRPSA
CEEECCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHH
VAVARALAEGAKVVACSSTGNAASSLAGAAASVGLKAVIFVPGRAPQGKVAQLLIFGATV
HHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHEEEEEEE
ISVQGSYEDAFKLSAAAIAEHGWYNRNAAINPYLVEGKKTVCLEVAEQLNWEVPDWVVLS
EEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCEEEEE
VGDGCTMAGAWKAWVDLKKAGWIDKLPRMLGVQAEGCCPITRAFREGTRVKPMPENTLAD
ECCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCHHHH
SIAVGVPRNPEKALRAVRDSGGTMINVSDEEILAAMRTLGRTSGIFGEPAGAAGTAGLIK
HEEECCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
AVQEGIIKSGDKVVVLVTGNGLKDVANAIKAAGEPIRVEPSLEALKEALARYGK
HHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]