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The map label for this gene is sdaAA [H]

Identifier: 83590778

GI number: 83590778

Start: 2020555

End: 2021496

Strand: Reverse

Name: sdaAA [H]

Synonym: Moth_1946

Alternate gene names: 83590778

Gene position: 2021496-2020555 (Counterclockwise)

Preceding gene: 83590779

Following gene: 83590777

Centisome position: 76.9

GC content: 67.2

Gene sequence:

>942_bases
TTGACCCGGTATAATTTTCAAAGCATGGCTGAACTCCTGCAGATAGCCGCGGATGAAGGGCTGACCCTGGCCGGGGTAGT
CATCCGCTACCAGGAAGACCTGGAGGGTAAGAGCCGCGAAGAGGTGCGCCGGGCGATGGGGGAGAGGCTGGCCGTTATGC
GGGCGGCTGCCAGGAAAGGGTTGCATGAAGACATCCGTTCCCCCAGCGGCCTGGTAGGCGGGGGCGGAAAACTCCTGGAG
GAAAGGCGCCTGGCAGGGCAGAGCCTCTGTGCCGCCACCACCGCCCGGGCCATTGCCCTGGCCATGGCCGTAGCTGAGGT
CAACGCTTCCATGGGCCGGGTGGTAGCCGCGCCGACGGCTGGCTCCTGCGGCATCCTTCCAGGGGTCCTGCTGGCCCTGG
AAGCGGAAAAGGGGCTGGACGAAGACCTGCTTATCGATGGGCTCTTTGCGGCCGCCGGTATCGGCATGGTGGCCGCCGGG
CAGGCCTCCCTTTCGGGGGCCGCCCTGGGGTGCCAGGCCGAGGTAGGGGTGGCCGCCGCCATGGCGGCAGCGGCGGCCGT
GGAAATGACCGGAGGGGATGCGGTCCAGGCCGCCAACGCCGCCGGGGTCGCCCTGCAGGGCCTGATGGGACTGGTCTGCG
ACCCCGTGGGTGGCCTGGTGGAGGTCCCCTGCGTCATGCGCAACGCCATGGGCGCGGCCCAGGCCCTGGTGGCGGCCGAC
ATTGCCCTGGCCGGCGTCCAGTGCTATATACCTTTTGATGAAATAGTCGCAGCCATGGTCCAGGTCGGTCGCGCCCTGCC
GCCGGAATTACGGGAGACGGGTGCCGGCGGGATAGCCGCCTGTCCCACCGCCCGGAAACTGGCCCGGCAGATCGGGATCA
AAACCCTGGACAAGGATTCTCTCCAGGAGAATCTTTCGGTAGCAAGCCCTGGTATCCCTTAA

Upstream 100 bases:

>100_bases
GGTGAACAGGCCCTGATGGTCGTCGAAACCGACCAGGCAATTCCTCCGGGGCTGGTGCCGGCCATGCGGGCCCTACCAAT
GATGGAGCGGGTGATCCAGA

Downstream 100 bases:

>100_bases
GGGTTACCGGGTTTTTGTATTAGTCAAAGAAATACGGTGAATTTCACTAGGTGATTACGATTCCAGTGCTATCCAATCCC
CCCAAAGACACCTGCAAACT

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTRYNFQSMAELLQIAADEGLTLAGVVIRYQEDLEGKSREEVRRAMGERLAVMRAAARKGLHEDIRSPSGLVGGGGKLLE
ERRLAGQSLCAATTARAIALAMAVAEVNASMGRVVAAPTAGSCGILPGVLLALEAEKGLDEDLLIDGLFAAAGIGMVAAG
QASLSGAALGCQAEVGVAAAMAAAAAVEMTGGDAVQAANAAGVALQGLMGLVCDPVGGLVEVPCVMRNAMGAAQALVAAD
IALAGVQCYIPFDEIVAAMVQVGRALPPELRETGAGGIAACPTARKLARQIGIKTLDKDSLQENLSVASPGIP

Sequences:

>Translated_313_residues
MTRYNFQSMAELLQIAADEGLTLAGVVIRYQEDLEGKSREEVRRAMGERLAVMRAAARKGLHEDIRSPSGLVGGGGKLLE
ERRLAGQSLCAATTARAIALAMAVAEVNASMGRVVAAPTAGSCGILPGVLLALEAEKGLDEDLLIDGLFAAAGIGMVAAG
QASLSGAALGCQAEVGVAAAMAAAAAVEMTGGDAVQAANAAGVALQGLMGLVCDPVGGLVEVPCVMRNAMGAAQALVAAD
IALAGVQCYIPFDEIVAAMVQVGRALPPELRETGAGGIAACPTARKLARQIGIKTLDKDSLQENLSVASPGIP
>Mature_312_residues
TRYNFQSMAELLQIAADEGLTLAGVVIRYQEDLEGKSREEVRRAMGERLAVMRAAARKGLHEDIRSPSGLVGGGGKLLEE
RRLAGQSLCAATTARAIALAMAVAEVNASMGRVVAAPTAGSCGILPGVLLALEAEKGLDEDLLIDGLFAAAGIGMVAAGQ
ASLSGAALGCQAEVGVAAAMAAAAAVEMTGGDAVQAANAAGVALQGLMGLVCDPVGGLVEVPCVMRNAMGAAQALVAADI
ALAGVQCYIPFDEIVAAMVQVGRALPPELRETGAGGIAACPTARKLARQIGIKTLDKDSLQENLSVASPGIP

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=284, Percent_Identity=33.4507042253521, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788116, Length=284, Percent_Identity=34.1549295774648, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789161, Length=292, Percent_Identity=35.958904109589, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 31513; Mature: 31382

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYNFQSMAELLQIAADEGLTLAGVVIRYQEDLEGKSREEVRRAMGERLAVMRAAARKG
CCCCCHHHHHHHHHHHHCCCCEEEHHHEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
LHEDIRSPSGLVGGGGKLLEERRLAGQSLCAATTARAIALAMAVAEVNASMGRVVAAPTA
HHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCC
GSCGILPGVLLALEAEKGLDEDLLIDGLFAAAGIGMVAAGQASLSGAALGCQAEVGVAAA
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCHHHHHHHH
MAAAAAVEMTGGDAVQAANAAGVALQGLMGLVCDPVGGLVEVPCVMRNAMGAAQALVAAD
HHHHHHHEECCCCHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
IALAGVQCYIPFDEIVAAMVQVGRALPPELRETGAGGIAACPTARKLARQIGIKTLDKDS
HHHHCEEEEECHHHHHHHHHHHHCCCCHHHHHCCCCCEEECHHHHHHHHHHCCCCCCHHH
LQENLSVASPGIP
HHHCCCCCCCCCC
>Mature Secondary Structure 
TRYNFQSMAELLQIAADEGLTLAGVVIRYQEDLEGKSREEVRRAMGERLAVMRAAARKG
CCCCHHHHHHHHHHHHCCCCEEEHHHEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
LHEDIRSPSGLVGGGGKLLEERRLAGQSLCAATTARAIALAMAVAEVNASMGRVVAAPTA
HHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCC
GSCGILPGVLLALEAEKGLDEDLLIDGLFAAAGIGMVAAGQASLSGAALGCQAEVGVAAA
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCHHHHHHHH
MAAAAAVEMTGGDAVQAANAAGVALQGLMGLVCDPVGGLVEVPCVMRNAMGAAQALVAAD
HHHHHHHEECCCCHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
IALAGVQCYIPFDEIVAAMVQVGRALPPELRETGAGGIAACPTARKLARQIGIKTLDKDS
HHHHCEEEEECHHHHHHHHHHHHCCCCHHHHHCCCCCEEECHHHHHHHHHHCCCCCCHHH
LQENLSVASPGIP
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]