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The map label for this gene is ygcA [C]

Identifier: 83590746

GI number: 83590746

Start: 1981394

End: 1982815

Strand: Reverse

Name: ygcA [C]

Synonym: Moth_1912

Alternate gene names: 83590746

Gene position: 1982815-1981394 (Counterclockwise)

Preceding gene: 83590747

Following gene: 83590744

Centisome position: 75.43

GC content: 62.59

Gene sequence:

>1422_bases
GTGGACTCGGCTATTACCATTATCGGGTTAAACCATGAAGGCGCCGGGATCGGTCATCTGCAGGACGGACGGGTTATCTT
TGTGCCCGGAGCCCTGCCGGGGGAACAGGTCCTGGTGGAAGTAGTCAGCGTTAAAAGGAATTACGCCAGGGGTCGGCTGG
TAGAGGTCGTAGAGGCGTCGCCGGACCGGGTGTTGCCCCCCTGCCCGGAAGCGGCCTCCTGTGGCGGGTGCGATCTGCAA
CACCTGGACTATCGGGCCCAGTTGCATTGGAAGCGTCGTCTGGTAATCGATGCCTTGCAACGCCTGGGACATCTGAGGGA
TATCCCGGTGCTACCCGTTCTGGGTATGGCTAATCCCTGGGGTTACCGCAACAAGGTGCGGCTGCATGTCCGCCGGGGGC
GGCTGGGCTTTTACCGCCCGGGAAGCCACGAGTTAGCACCCTTCTCCTGCTGTCCATTGTTACCCCCCGGCCTTCTGAAG
GCGGCCCGGGCGATCGTGCGGTTGCTGCCGGAACTGCCACCCGGCCTGCAGCATGTAACCCTGCGCCAGGGCCTGGCTAC
CGGGGAACTGCTGGTTGTCCTGGAGGCTTTACCTGGATGGCAGGGCGATAGGGAACTGGCGGAGAAACTGGCCGGCAGAT
TCCCGGAACTGGTGGGGGTTGTATCCCTGGCTGGCGGCGGCAGGAGCAGGAGCGGTCCAAAGGATTTTGCCGGGGAGCCT
GCTTTAGAGTGCAGCGGCTGGGTAAAAACAGGCGGGAAAGAAGCAAGGCGGGCCCGGTACCAGGAAGGATTCGTGCCCCG
CAGGCTAGGTGGCCGGCCCTTCACCCTCTATGGCCGTGATTACCTGGAGGAACGCCTTGGTGACCTCCGCTTCTATATAT
CAGCCACGACCTTTTTCCAGGTTAATTCGGCCCAGGCGGAAGTCCTCTATAACAAGGCGGCAACCTTTGCCGGCCTGCAG
GGCGGGGAAGAGGTTCTGGACGCCTACTGCGGCAGCGGTGCCATTGCCCTGTGGCTCAGCCGCCAGGCCGGGCGGGTGGA
GGGGGTGGAAGTAGTCCCGGAGGCCATTGTTGACGCCCGGCGCAATTCAATTTTAAACAACCTGGCCAATGTCCACTTTC
GTACCGGCGCTGCCGAGGCGGTCCTGCCCCGCCTGGCAGGAAAGGGTTACCGGCCGGAGGTAATTATCCTGGATCCGCCC
CGGGCCGGATGCGACCGCCGGGTGCTGGCGGCCGTGGCGACTATGGAACCCCGGCGGGTGGTCTACATCTCCTGCAACCC
GTCAACTTTAGCCCGCGACCTGGCACACTTACGGGAAGCTGGCTTTAAGCCCGGCCCGGTGCAGCCGGTGGACATGTTCC
CCCATACCCACCATGTGGAGTGTTGCTGCTTTCTTGTAAAGGAGAGAAATAACAGCCGCTGA

Upstream 100 bases:

>100_bases
ATGATCGTACCGGCAATATCCTGGCTTCTATTATTGCCCATGCCACTTGGAATACGATTATGATTCTTCTCCTTTACTTT
GCTCTACGGTGGGTTTAACT

Downstream 100 bases:

>100_bases
GAAGGCGGCCCCCAACAAGAAACCATTTAATATTTATTATAATTTGTAAATTGTAATTAACGGAGGTTCCACCTCTCCTT
GCGTCCGTTAATCGGAGCGA

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MDSAITIIGLNHEGAGIGHLQDGRVIFVPGALPGEQVLVEVVSVKRNYARGRLVEVVEASPDRVLPPCPEAASCGGCDLQ
HLDYRAQLHWKRRLVIDALQRLGHLRDIPVLPVLGMANPWGYRNKVRLHVRRGRLGFYRPGSHELAPFSCCPLLPPGLLK
AARAIVRLLPELPPGLQHVTLRQGLATGELLVVLEALPGWQGDRELAEKLAGRFPELVGVVSLAGGGRSRSGPKDFAGEP
ALECSGWVKTGGKEARRARYQEGFVPRRLGGRPFTLYGRDYLEERLGDLRFYISATTFFQVNSAQAEVLYNKAATFAGLQ
GGEEVLDAYCGSGAIALWLSRQAGRVEGVEVVPEAIVDARRNSILNNLANVHFRTGAAEAVLPRLAGKGYRPEVIILDPP
RAGCDRRVLAAVATMEPRRVVYISCNPSTLARDLAHLREAGFKPGPVQPVDMFPHTHHVECCCFLVKERNNSR

Sequences:

>Translated_473_residues
MDSAITIIGLNHEGAGIGHLQDGRVIFVPGALPGEQVLVEVVSVKRNYARGRLVEVVEASPDRVLPPCPEAASCGGCDLQ
HLDYRAQLHWKRRLVIDALQRLGHLRDIPVLPVLGMANPWGYRNKVRLHVRRGRLGFYRPGSHELAPFSCCPLLPPGLLK
AARAIVRLLPELPPGLQHVTLRQGLATGELLVVLEALPGWQGDRELAEKLAGRFPELVGVVSLAGGGRSRSGPKDFAGEP
ALECSGWVKTGGKEARRARYQEGFVPRRLGGRPFTLYGRDYLEERLGDLRFYISATTFFQVNSAQAEVLYNKAATFAGLQ
GGEEVLDAYCGSGAIALWLSRQAGRVEGVEVVPEAIVDARRNSILNNLANVHFRTGAAEAVLPRLAGKGYRPEVIILDPP
RAGCDRRVLAAVATMEPRRVVYISCNPSTLARDLAHLREAGFKPGPVQPVDMFPHTHHVECCCFLVKERNNSR
>Mature_473_residues
MDSAITIIGLNHEGAGIGHLQDGRVIFVPGALPGEQVLVEVVSVKRNYARGRLVEVVEASPDRVLPPCPEAASCGGCDLQ
HLDYRAQLHWKRRLVIDALQRLGHLRDIPVLPVLGMANPWGYRNKVRLHVRRGRLGFYRPGSHELAPFSCCPLLPPGLLK
AARAIVRLLPELPPGLQHVTLRQGLATGELLVVLEALPGWQGDRELAEKLAGRFPELVGVVSLAGGGRSRSGPKDFAGEP
ALECSGWVKTGGKEARRARYQEGFVPRRLGGRPFTLYGRDYLEERLGDLRFYISATTFFQVNSAQAEVLYNKAATFAGLQ
GGEEVLDAYCGSGAIALWLSRQAGRVEGVEVVPEAIVDARRNSILNNLANVHFRTGAAEAVLPRLAGKGYRPEVIILDPP
RAGCDRRVLAAVATMEPRRVVYISCNPSTLARDLAHLREAGFKPGPVQPVDMFPHTHHVECCCFLVKERNNSR

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=256, Percent_Identity=37.109375, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI51173878, Length=256, Percent_Identity=37.109375, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI269784680, Length=201, Percent_Identity=32.8358208955224, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI269784676, Length=201, Percent_Identity=32.8358208955224, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI20149688, Length=201, Percent_Identity=32.8358208955224, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI269784678, Length=201, Percent_Identity=32.8358208955224, Blast_Score=109, Evalue=4e-24,
Organism=Escherichia coli, GI1789148, Length=475, Percent_Identity=30.1052631578947, Blast_Score=178, Evalue=9e-46,
Organism=Escherichia coli, GI1787083, Length=199, Percent_Identity=31.6582914572864, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790403, Length=205, Percent_Identity=30.7317073170732, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71997438, Length=161, Percent_Identity=31.6770186335404, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322909, Length=151, Percent_Identity=31.1258278145695, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24666579, Length=455, Percent_Identity=29.010989010989, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280
- InterPro:   IPR003402 [H]

Pfam domain/function: PF02475 Met_10; PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 51717; Mature: 51717

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50926 TRAM ; PS01230 TRMA_1 ; PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSAITIIGLNHEGAGIGHLQDGRVIFVPGALPGEQVLVEVVSVKRNYARGRLVEVVEAS
CCCEEEEEEECCCCCCCCEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
PDRVLPPCPEAASCGGCDLQHLDYRAQLHWKRRLVIDALQRLGHLRDIPVLPVLGMANPW
CCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GYRNKVRLHVRRGRLGFYRPGSHELAPFSCCPLLPPGLLKAARAIVRLLPELPPGLQHVT
CCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
LRQGLATGELLVVLEALPGWQGDRELAEKLAGRFPELVGVVSLAGGGRSRSGPKDFAGEP
HHHCCCCCHHEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHEECCCCCCCCCCCCCCCCC
ALECSGWVKTGGKEARRARYQEGFVPRRLGGRPFTLYGRDYLEERLGDLRFYISATTFFQ
CCCCCCHHHCCCHHHHHHHHHHCCCCHHCCCCEEEECCHHHHHHHHCCEEEEEEEEEEEE
VNSAQAEVLYNKAATFAGLQGGEEVLDAYCGSGAIALWLSRQAGRVEGVEVVPEAIVDAR
ECCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHH
RNSILNNLANVHFRTGAAEAVLPRLAGKGYRPEVIILDPPRAGCDRRVLAAVATMEPRRV
HHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCEE
VYISCNPSTLARDLAHLREAGFKPGPVQPVDMFPHTHHVECCCFLVKERNNSR
EEEECCHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCHHHHEEEEECCCCCC
>Mature Secondary Structure
MDSAITIIGLNHEGAGIGHLQDGRVIFVPGALPGEQVLVEVVSVKRNYARGRLVEVVEAS
CCCEEEEEEECCCCCCCCEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
PDRVLPPCPEAASCGGCDLQHLDYRAQLHWKRRLVIDALQRLGHLRDIPVLPVLGMANPW
CCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GYRNKVRLHVRRGRLGFYRPGSHELAPFSCCPLLPPGLLKAARAIVRLLPELPPGLQHVT
CCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
LRQGLATGELLVVLEALPGWQGDRELAEKLAGRFPELVGVVSLAGGGRSRSGPKDFAGEP
HHHCCCCCHHEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHEECCCCCCCCCCCCCCCCC
ALECSGWVKTGGKEARRARYQEGFVPRRLGGRPFTLYGRDYLEERLGDLRFYISATTFFQ
CCCCCCHHHCCCHHHHHHHHHHCCCCHHCCCCEEEECCHHHHHHHHCCEEEEEEEEEEEE
VNSAQAEVLYNKAATFAGLQGGEEVLDAYCGSGAIALWLSRQAGRVEGVEVVPEAIVDAR
ECCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHH
RNSILNNLANVHFRTGAAEAVLPRLAGKGYRPEVIILDPPRAGCDRRVLAAVATMEPRRV
HHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCEE
VYISCNPSTLARDLAHLREAGFKPGPVQPVDMFPHTHHVECCCFLVKERNNSR
EEEECCHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCHHHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA