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The map label for this gene is typA [H]

Identifier: 83590728

GI number: 83590728

Start: 1958467

End: 1960245

Strand: Reverse

Name: typA [H]

Synonym: Moth_1894

Alternate gene names: 83590728

Gene position: 1960245-1958467 (Counterclockwise)

Preceding gene: 83590729

Following gene: 83590727

Centisome position: 74.57

GC content: 60.31

Gene sequence:

>1779_bases
ATGGACCAGCAAAAGATACGCAACCTGGCGATAATCGCCCACGTCGATCATGGCAAGACGACCCTGGTCGACGGCATGCT
GAAACAGAGCGGCATTTTCCACGAGAAGCAGGTGGTCCAGGAGCGTATCCTGGACCGCAACGATCTGGAACGGGAACGCG
GCATCACTATCATGGCCAAGAATACCGCTGTCTTTTACCGGGGTTACAAGCTGAACATCGTCGACACCCCCGGCCACGCC
GATTTCGGCGGCGAAGTGGAGCGCATCGTCCAGATGGTGGACGGGGCCCTCCTACTGGTGGACGCCTTCGAGGGCCCCAT
GCCCCAGACTCGTTTTGTCCTGAAAAAGGCCCTGGCGGTGGGTCTGAAACCCATTGTGGTCATCAATAAAATGGACCGGC
CCAACGCCCGGCCGGGGGCGGTGGTCGACGAAGTCCTGGACCTTTTCATCGACCTGGGAGCCACCGAGGAGCAGCTGGAT
TTCCCGGTGGTCTACACAGTAGCCCGCCAGGGAACGGCCAGCCTGGACCCGGACCAGCCCGGGAAAGACCTGCAGCCTCT
GTTTGACATAATCGTCCAGCATATACCAGCCCCCGGCGGGGACCCGGAGGCAACCCTGCAGGTAGGAGTCAACCTCATTG
ATTATGACACTTATGTCGGCCGCCAGGCCATCGGCCGGGTATATAACGGCACCATCCGCGCCCGGCAGGAAGTGGCCGTT
GCCCGGCCCGACGGCAGCCTGGTCCGGGGGCATGTGGCTGCCCTGCATGTTTTTGAAGGTCTCAACAAGGTGCCGGTGGA
TGAAGCCGCCGCCGGGGAGATCGTCGTCGTCAGCGGCCTGGAGGACATCAACGTCGCCAATACCATTACCTCGCCGGAGG
ACCCCCGGCCCCTGGACTTTGTCCGTATCGACGAGCCCACGGTGGCTATGACTTTCATGGTCAATAAGAGCCCCTTCGCC
GGCCGGGAAGGGGAGTATGTAACTTCCCGGAAGCTCCGGGAGCGCCTCCTCAGGGAGGCGGAATCGGATGTCAGCCTGCG
GGTGGAGGAAACGGATTCCCCTGACGCCCTGCTGGTTTCCGGCCGGGGCGAGCTGCACCTCGCCATCCTCATCGAAACCA
TGCGCCGGGAGGGGTATGAATTCGAAGTCTCCCGGCCCCAGGCGATTATTAAAGAAATAAAGGGCGTCAAGTGCGAGCCC
GTTGAAGAACTCATTATAGAGGTTCCGGAAACCTATATGGGCATCGTCATCGAGCGCCTGGGTCCCCGCAAAAGCGAGAT
GGTCAACCTGGAAAACAAGGGGGACGGCCAGGTGCGCCTGACCTTTCATATCCCCACCCGGGGGCTCTTCGGCTTCCGTT
CCGAATTCCTTACCGATACTAAAGGTCTGGGCATCATGCACCACGCCTTTCACCATTACGCCCCCTATGCCGGGGAGATT
GCTACCCGGACGCGTGGTTCTCTGGTGGCCTTTGAAACCGGGGAAACAACCAGCTATGGCCTGGAGAACGCCCAGGAGCG
GGGCGAGCTCTTTGTCGGCCCTGGGGTACCAGTCTACCGGGGGATGATTGTCGGCGAGCATTCCCGGCCCGGCGACCTGA
TGATCAACGTCTGCAAAAAAAAGCAACTGACCAACGTCCGCAGTTCTACCGCCGATATTGCTATCAAACTGGTCCCGCCC
CGGGAGATGACCCTGGAGCAGTGCCTGGAATTTATCGCTGCCGACGAACTCCTGGAAGTGACGCCCAGGTCCCTCAGGAT
GCGAAAGAGGGATATATAA

Upstream 100 bases:

>100_bases
GAGGTTATGTCCAGCCCCCTCACCCTTGCGCGGTCCCCTTCCTTGCGTTATACTCTATTCGGCAAAGGATAATAAAGAAT
AAGTTGACGGAAGGAATCCC

Downstream 100 bases:

>100_bases
CGGAGCAGGCAGCAGGCGCTTCGGTCGATCGCGATTGCCTTCGCAGCCGTCGCTAACCCCTTCGCAATAGGTGTACTGTA
TACATGCCGGGATTCTGTTG

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MDQQKIRNLAIIAHVDHGKTTLVDGMLKQSGIFHEKQVVQERILDRNDLERERGITIMAKNTAVFYRGYKLNIVDTPGHA
DFGGEVERIVQMVDGALLLVDAFEGPMPQTRFVLKKALAVGLKPIVVINKMDRPNARPGAVVDEVLDLFIDLGATEEQLD
FPVVYTVARQGTASLDPDQPGKDLQPLFDIIVQHIPAPGGDPEATLQVGVNLIDYDTYVGRQAIGRVYNGTIRARQEVAV
ARPDGSLVRGHVAALHVFEGLNKVPVDEAAAGEIVVVSGLEDINVANTITSPEDPRPLDFVRIDEPTVAMTFMVNKSPFA
GREGEYVTSRKLRERLLREAESDVSLRVEETDSPDALLVSGRGELHLAILIETMRREGYEFEVSRPQAIIKEIKGVKCEP
VEELIIEVPETYMGIVIERLGPRKSEMVNLENKGDGQVRLTFHIPTRGLFGFRSEFLTDTKGLGIMHHAFHHYAPYAGEI
ATRTRGSLVAFETGETTSYGLENAQERGELFVGPGVPVYRGMIVGEHSRPGDLMINVCKKKQLTNVRSSTADIAIKLVPP
REMTLEQCLEFIAADELLEVTPRSLRMRKRDI

Sequences:

>Translated_592_residues
MDQQKIRNLAIIAHVDHGKTTLVDGMLKQSGIFHEKQVVQERILDRNDLERERGITIMAKNTAVFYRGYKLNIVDTPGHA
DFGGEVERIVQMVDGALLLVDAFEGPMPQTRFVLKKALAVGLKPIVVINKMDRPNARPGAVVDEVLDLFIDLGATEEQLD
FPVVYTVARQGTASLDPDQPGKDLQPLFDIIVQHIPAPGGDPEATLQVGVNLIDYDTYVGRQAIGRVYNGTIRARQEVAV
ARPDGSLVRGHVAALHVFEGLNKVPVDEAAAGEIVVVSGLEDINVANTITSPEDPRPLDFVRIDEPTVAMTFMVNKSPFA
GREGEYVTSRKLRERLLREAESDVSLRVEETDSPDALLVSGRGELHLAILIETMRREGYEFEVSRPQAIIKEIKGVKCEP
VEELIIEVPETYMGIVIERLGPRKSEMVNLENKGDGQVRLTFHIPTRGLFGFRSEFLTDTKGLGIMHHAFHHYAPYAGEI
ATRTRGSLVAFETGETTSYGLENAQERGELFVGPGVPVYRGMIVGEHSRPGDLMINVCKKKQLTNVRSSTADIAIKLVPP
REMTLEQCLEFIAADELLEVTPRSLRMRKRDI
>Mature_592_residues
MDQQKIRNLAIIAHVDHGKTTLVDGMLKQSGIFHEKQVVQERILDRNDLERERGITIMAKNTAVFYRGYKLNIVDTPGHA
DFGGEVERIVQMVDGALLLVDAFEGPMPQTRFVLKKALAVGLKPIVVINKMDRPNARPGAVVDEVLDLFIDLGATEEQLD
FPVVYTVARQGTASLDPDQPGKDLQPLFDIIVQHIPAPGGDPEATLQVGVNLIDYDTYVGRQAIGRVYNGTIRARQEVAV
ARPDGSLVRGHVAALHVFEGLNKVPVDEAAAGEIVVVSGLEDINVANTITSPEDPRPLDFVRIDEPTVAMTFMVNKSPFA
GREGEYVTSRKLRERLLREAESDVSLRVEETDSPDALLVSGRGELHLAILIETMRREGYEFEVSRPQAIIKEIKGVKCEP
VEELIIEVPETYMGIVIERLGPRKSEMVNLENKGDGQVRLTFHIPTRGLFGFRSEFLTDTKGLGIMHHAFHHYAPYAGEI
ATRTRGSLVAFETGETTSYGLENAQERGELFVGPGVPVYRGMIVGEHSRPGDLMINVCKKKQLTNVRSSTADIAIKLVPP
REMTLEQCLEFIAADELLEVTPRSLRMRKRDI

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=391, Percent_Identity=29.4117647058824, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI94966754, Length=132, Percent_Identity=41.6666666666667, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI4503483, Length=150, Percent_Identity=38.6666666666667, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI18390331, Length=148, Percent_Identity=36.4864864864865, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI25306287, Length=143, Percent_Identity=38.4615384615385, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI19923640, Length=143, Percent_Identity=38.4615384615385, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI25306283, Length=143, Percent_Identity=38.4615384615385, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=38.7387387387387, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=38.7387387387387, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=38.7387387387387, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI34147630, Length=199, Percent_Identity=33.1658291457286, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI217272894, Length=140, Percent_Identity=35.7142857142857, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI217272892, Length=140, Percent_Identity=35.7142857142857, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI94966752, Length=128, Percent_Identity=31.25, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI48994988, Length=590, Percent_Identity=52.3728813559322, Blast_Score=634, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=509, Percent_Identity=29.2730844793713, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1789738, Length=150, Percent_Identity=37.3333333333333, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1790835, Length=147, Percent_Identity=31.2925170068027, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790412, Length=129, Percent_Identity=36.4341085271318, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1789737, Length=129, Percent_Identity=36.4341085271318, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17557151, Length=287, Percent_Identity=33.4494773519164, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17506493, Length=162, Percent_Identity=35.8024691358025, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17556745, Length=143, Percent_Identity=39.8601398601399, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71988819, Length=130, Percent_Identity=36.1538461538462, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71988811, Length=130, Percent_Identity=36.1538461538462, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17533571, Length=146, Percent_Identity=41.0958904109589, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=33.5820895522388, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17556456, Length=278, Percent_Identity=27.3381294964029, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323320, Length=500, Percent_Identity=26, Blast_Score=133, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6324707, Length=150, Percent_Identity=38.6666666666667, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320593, Length=150, Percent_Identity=38.6666666666667, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324166, Length=146, Percent_Identity=39.041095890411, Blast_Score=98, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6322359, Length=151, Percent_Identity=38.4105960264901, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323098, Length=151, Percent_Identity=36.4238410596026, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324761, Length=269, Percent_Identity=27.8810408921933, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI78706572, Length=531, Percent_Identity=25.2354048964218, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28574573, Length=140, Percent_Identity=41.4285714285714, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24585709, Length=154, Percent_Identity=37.012987012987, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24585711, Length=154, Percent_Identity=37.012987012987, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24585713, Length=154, Percent_Identity=37.012987012987, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24582462, Length=147, Percent_Identity=37.4149659863946, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357743, Length=134, Percent_Identity=40.2985074626866, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI221458488, Length=149, Percent_Identity=36.9127516778523, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI281363316, Length=301, Percent_Identity=26.578073089701, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17864358, Length=301, Percent_Identity=26.578073089701, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19921738, Length=126, Percent_Identity=38.0952380952381, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 65645; Mature: 65645

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQQKIRNLAIIAHVDHGKTTLVDGMLKQSGIFHEKQVVQERILDRNDLERERGITIMAK
CCHHHHCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHCCEEEEEE
NTAVFYRGYKLNIVDTPGHADFGGEVERIVQMVDGALLLVDAFEGPMPQTRFVLKKALAV
CEEEEEECEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHH
GLKPIVVINKMDRPNARPGAVVDEVLDLFIDLGATEEQLDFPVVYTVARQGTASLDPDQP
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCEEEEEECCCCCCCCCCCC
GKDLQPLFDIIVQHIPAPGGDPEATLQVGVNLIDYDTYVGRQAIGRVYNGTIRARQEVAV
CCCHHHHHHHHHHHCCCCCCCCCCEEEECCEEEECHHHHHHHHHHHHHCCCCEECCEEEE
ARPDGSLVRGHVAALHVFEGLNKVPVDEAAAGEIVVVSGLEDINVANTITSPEDPRPLDF
ECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCE
VRIDEPTVAMTFMVNKSPFAGREGEYVTSRKLRERLLREAESDVSLRVEETDSPDALLVS
EEECCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEE
GRGELHLAILIETMRREGYEFEVSRPQAIIKEIKGVKCEPVEELIIEVPETYMGIVIERL
CCCCEEEEHEEHHHHHCCCEEEECCHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHC
GPRKSEMVNLENKGDGQVRLTFHIPTRGLFGFRSEFLTDTKGLGIMHHAFHHYAPYAGEI
CCCHHHEEECCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCH
ATRTRGSLVAFETGETTSYGLENAQERGELFVGPGVPVYRGMIVGEHSRPGDLMINVCKK
HHCCCCCEEEEECCCCCCCCCCCHHHCCCEEECCCCHHHEEEEEECCCCCCHHHHHHHHH
KQLTNVRSSTADIAIKLVPPREMTLEQCLEFIAADELLEVTPRSLRMRKRDI
HHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MDQQKIRNLAIIAHVDHGKTTLVDGMLKQSGIFHEKQVVQERILDRNDLERERGITIMAK
CCHHHHCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHCCEEEEEE
NTAVFYRGYKLNIVDTPGHADFGGEVERIVQMVDGALLLVDAFEGPMPQTRFVLKKALAV
CEEEEEECEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHH
GLKPIVVINKMDRPNARPGAVVDEVLDLFIDLGATEEQLDFPVVYTVARQGTASLDPDQP
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCEEEEEECCCCCCCCCCCC
GKDLQPLFDIIVQHIPAPGGDPEATLQVGVNLIDYDTYVGRQAIGRVYNGTIRARQEVAV
CCCHHHHHHHHHHHCCCCCCCCCCEEEECCEEEECHHHHHHHHHHHHHCCCCEECCEEEE
ARPDGSLVRGHVAALHVFEGLNKVPVDEAAAGEIVVVSGLEDINVANTITSPEDPRPLDF
ECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCE
VRIDEPTVAMTFMVNKSPFAGREGEYVTSRKLRERLLREAESDVSLRVEETDSPDALLVS
EEECCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEE
GRGELHLAILIETMRREGYEFEVSRPQAIIKEIKGVKCEPVEELIIEVPETYMGIVIERL
CCCCEEEEHEEHHHHHCCCEEEECCHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHC
GPRKSEMVNLENKGDGQVRLTFHIPTRGLFGFRSEFLTDTKGLGIMHHAFHHYAPYAGEI
CCCHHHEEECCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCH
ATRTRGSLVAFETGETTSYGLENAQERGELFVGPGVPVYRGMIVGEHSRPGDLMINVCKK
HHCCCCCEEEEECCCCCCCCCCCHHHCCCEEECCCCHHHEEEEEECCCCCCHHHHHHHHH
KQLTNVRSSTADIAIKLVPPREMTLEQCLEFIAADELLEVTPRSLRMRKRDI
HHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]