Click here to switch to the map view.

The map label for this gene is coaE

Identifier: 83590672

GI number: 83590672

Start: 1895292

End: 1895930

Strand: Reverse

Name: coaE

Synonym: Moth_1838

Alternate gene names: 83590672

Gene position: 1895930-1895292 (Counterclockwise)

Preceding gene: 83590673

Following gene: 83590671

Centisome position: 72.12

GC content: 62.6

Gene sequence:

>639_bases
ATGTTTATTATCGGTCTTACCGGTGGTATTGCCAGCGGCAAGAGTACCGTAGCCGGTATTCTCAAGGACCTGGGAGCAAT
TATAATCGATACCGACCGGGTAGCCAGGGAGGTAGTGGCCCCCGGCCGCCCCGCCTACCGGGAGATTGTGGCCGCCTTTG
GCCCCCGGGTCCTGCGACCTGACGGCCAGCTGGACAGGCCGGCCTTAGCTCGGATTATTTTTAATGACGCTACCGCCAGG
GAACTATTAAATGCCATCACCCACCCCAGGATCCGGGAGCTGGTCCAGAAGCGTTTGGAAGATTTGCGCCGGGCCAACCC
GGAAGCAATAGTGGTGATTGAGGCGCCCCTGTTGTTTGAAGCCGGGATGGAGGGGATGGTGGATGCCGTCTGGGCAGTCA
CCGCCCCGGCTCCGGTGCGCTTAAAGAGGTTGATGGCCAGGGACAAGCTCTCCCTGGCTGAGGCAGAGAGCCGCCTCCGG
GCTCAAGGTGAAGAGACAGCCAGGTTGCGCCGGGCCACCAGGGTGATTCCCACCGGCGGTGACCTGGAGGCTACCCGGGC
TTCCGTCCGGGCGGCCTGGCAGGAACTGCAGCGCCACCTGGCAGATGATCCAGAGCCCGGAGGTGCCCCATGGGTTTAG

Upstream 100 bases:

>100_bases
GGGAATACTGGGGGCTGGAGAATCTCGGCTGGCGGGGAGCGGCTATACCGGGTTTAATCTTAATCGCCATTGGCCTCTGG
CGATTATAGGAGTGCGAGGG

Downstream 100 bases:

>100_bases
GAAGGCGTTTACTGTGGCTGCTTTTTTTGCTGGCCCTTCTCGCTTTTCTCCTGCCCCGGGCCGGCCGGTTACTTTATCCT
TTACCCTACCGCGATAGTAT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MFIIGLTGGIASGKSTVAGILKDLGAIIIDTDRVAREVVAPGRPAYREIVAAFGPRVLRPDGQLDRPALARIIFNDATAR
ELLNAITHPRIRELVQKRLEDLRRANPEAIVVIEAPLLFEAGMEGMVDAVWAVTAPAPVRLKRLMARDKLSLAEAESRLR
AQGEETARLRRATRVIPTGGDLEATRASVRAAWQELQRHLADDPEPGGAPWV

Sequences:

>Translated_212_residues
MFIIGLTGGIASGKSTVAGILKDLGAIIIDTDRVAREVVAPGRPAYREIVAAFGPRVLRPDGQLDRPALARIIFNDATAR
ELLNAITHPRIRELVQKRLEDLRRANPEAIVVIEAPLLFEAGMEGMVDAVWAVTAPAPVRLKRLMARDKLSLAEAESRLR
AQGEETARLRRATRVIPTGGDLEATRASVRAAWQELQRHLADDPEPGGAPWV
>Mature_212_residues
MFIIGLTGGIASGKSTVAGILKDLGAIIIDTDRVAREVVAPGRPAYREIVAAFGPRVLRPDGQLDRPALARIIFNDATAR
ELLNAITHPRIRELVQKRLEDLRRANPEAIVVIEAPLLFEAGMEGMVDAVWAVTAPAPVRLKRLMARDKLSLAEAESRLR
AQGEETARLRRATRVIPTGGDLEATRASVRAAWQELQRHLADDPEPGGAPWV

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=207, Percent_Identity=41.0628019323672, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI191252795, Length=207, Percent_Identity=41.0628019323672, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI110227607, Length=200, Percent_Identity=36.5, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI110227605, Length=200, Percent_Identity=36.5, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI110227603, Length=200, Percent_Identity=36.5, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI110227601, Length=200, Percent_Identity=36.5, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI205277394, Length=200, Percent_Identity=36.5, Blast_Score=122, Evalue=3e-28,
Organism=Escherichia coli, GI1786292, Length=208, Percent_Identity=36.0576923076923, Blast_Score=105, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17554944, Length=200, Percent_Identity=35.5, Blast_Score=125, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI25143409, Length=200, Percent_Identity=31.5, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320402, Length=202, Percent_Identity=34.1584158415842, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24644728, Length=195, Percent_Identity=35.8974358974359, Blast_Score=133, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24658602, Length=200, Percent_Identity=37, Blast_Score=131, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_MOOTA (Q2RHF1)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430681.1
- ProteinModelPortal:   Q2RHF1
- SMR:   Q2RHF1
- STRING:   Q2RHF1
- GeneID:   3831698
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1838
- NMPDR:   fig|264732.9.peg.1843
- eggNOG:   COG0237
- HOGENOM:   HBG650290
- OMA:   VVVYCDP
- PhylomeDB:   Q2RHF1
- BioCyc:   MTHE264732:MOTH_1838-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 23097; Mature: 23097

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS51219 DPCK; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIIGLTGGIASGKSTVAGILKDLGAIIIDTDRVAREVVAPGRPAYREIVAAFGPRVLRP
CEEEEECCCCCCCHHHHHHHHHHHCCEEECHHHHHHHHHCCCCHHHHHHHHHHCCEEECC
DGQLDRPALARIIFNDATARELLNAITHPRIRELVQKRLEDLRRANPEAIVVIEAPLLFE
CCCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHH
AGMEGMVDAVWAVTAPAPVRLKRLMARDKLSLAEAESRLRAQGEETARLRRATRVIPTGG
HCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
DLEATRASVRAAWQELQRHLADDPEPGGAPWV
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MFIIGLTGGIASGKSTVAGILKDLGAIIIDTDRVAREVVAPGRPAYREIVAAFGPRVLRP
CEEEEECCCCCCCHHHHHHHHHHHCCEEECHHHHHHHHHCCCCHHHHHHHHHHCCEEECC
DGQLDRPALARIIFNDATARELLNAITHPRIRELVQKRLEDLRRANPEAIVVIEAPLLFE
CCCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHH
AGMEGMVDAVWAVTAPAPVRLKRLMARDKLSLAEAESRLRAQGEETARLRRATRVIPTGG
HCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
DLEATRASVRAAWQELQRHLADDPEPGGAPWV
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA