Click here to switch to the map view.

The map label for this gene is mhpF [C]

Identifier: 83590611

GI number: 83590611

Start: 1831432

End: 1832307

Strand: Reverse

Name: mhpF [C]

Synonym: Moth_1776

Alternate gene names: 83590611

Gene position: 1832307-1831432 (Counterclockwise)

Preceding gene: 83590612

Following gene: 83590610

Centisome position: 69.7

GC content: 56.16

Gene sequence:

>876_bases
GTGGACAAGGTAAAAGTGGCTGTTATCGGCCCGGGCAATATCGGGTCCGACCTGATGTACAAGATCCTGCGCAGCCGGCA
TCTAGAGATGGCCCTGATGACCGGTATTATCGAATCCGAGGGCATCAAGCGGGCCAGGAAGCTGGGTATCAAGACATCCA
TCGAAGGTGTCAAGGCCGTCCTGGCGGAAGACGATATCAAGATTGTCTTTGACGCCACCGGGGCCAAACCCCACTTACAG
CATGCGCCGCTTTTAAAAGAAGCGGGCAAGATCGCCATCGACTTGACACCGGCGGCAGTAGGTCCCTACGTGGTACCCTG
TGTCAACCTGGACCAGGTTAAGGCCGAACCAAACCTTAACATGGTCACCTGCGGTGGCCAGGCTACAGTACCCATCGTCT
ATGCCATCAACCGGGTGGCCGGGGCCAGATACGCTGAGATTGTAGCCTGCATCGCTTCCAAGAGCGCCGGGCCGGGGACC
CGCCAGAACATTGACGAGTTCACCCAGACTACGGCCAAGGCCCTGGAGGTTGTCGGCGGGGCGAAGAAGGGCAAAGCCAT
CATTATTCTGAATCCTGCCGAGCCACCCATTATGATGCATAACACCATTTATGTAGAGGTCGAAAAGCCCGACATCGAAG
CCATTCGCGCTTCGGTTGAAGCCATGGTCAAGGAAATCCAGAGCTATGTTCCCGGGTACCGGCTCGTCGTGCCGCCCATT
CTTGACGGCAACAAAGTAACGGCAGCTGTTGAAGTGGAGGGTGCTGGTGACTTCCTGCCCAAATACTCCGGTAATCTGGA
TATTATCACTTCAGCAGCCGTGGCGGTAGCTGAAAAGCTGGCCCAGGAACTGCAGGTAAAGGAAGGGGTAGCATGA

Upstream 100 bases:

>100_bases
GACGGCAGCCGAGAACGCCAGTGCCGGCGATGTCTTCACCGTATCCTTCTACGGCCTGGGGAGTCTGAGCCTGAAATTTA
TATAGCAAGGGGATGTTAGT

Downstream 100 bases:

>100_bases
GCGCTAGGTCAATCCACATTGTCGATACAACCCTGCGTGACGGTAGTCACGCCGTCAGCCACCAGTTTACGGCCGAGCAA
ATAGCCGCCATTGCCGGCGG

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MDKVKVAVIGPGNIGSDLMYKILRSRHLEMALMTGIIESEGIKRARKLGIKTSIEGVKAVLAEDDIKIVFDATGAKPHLQ
HAPLLKEAGKIAIDLTPAAVGPYVVPCVNLDQVKAEPNLNMVTCGGQATVPIVYAINRVAGARYAEIVACIASKSAGPGT
RQNIDEFTQTTAKALEVVGGAKKGKAIIILNPAEPPIMMHNTIYVEVEKPDIEAIRASVEAMVKEIQSYVPGYRLVVPPI
LDGNKVTAAVEVEGAGDFLPKYSGNLDIITSAAVAVAEKLAQELQVKEGVA

Sequences:

>Translated_291_residues
MDKVKVAVIGPGNIGSDLMYKILRSRHLEMALMTGIIESEGIKRARKLGIKTSIEGVKAVLAEDDIKIVFDATGAKPHLQ
HAPLLKEAGKIAIDLTPAAVGPYVVPCVNLDQVKAEPNLNMVTCGGQATVPIVYAINRVAGARYAEIVACIASKSAGPGT
RQNIDEFTQTTAKALEVVGGAKKGKAIIILNPAEPPIMMHNTIYVEVEKPDIEAIRASVEAMVKEIQSYVPGYRLVVPPI
LDGNKVTAAVEVEGAGDFLPKYSGNLDIITSAAVAVAEKLAQELQVKEGVA
>Mature_291_residues
MDKVKVAVIGPGNIGSDLMYKILRSRHLEMALMTGIIESEGIKRARKLGIKTSIEGVKAVLAEDDIKIVFDATGAKPHLQ
HAPLLKEAGKIAIDLTPAAVGPYVVPCVNLDQVKAEPNLNMVTCGGQATVPIVYAINRVAGARYAEIVACIASKSAGPGT
RQNIDEFTQTTAKALEVVGGAKKGKAIIILNPAEPPIMMHNTIYVEVEKPDIEAIRASVEAMVKEIQSYVPGYRLVVPPI
LDGNKVTAAVEVEGAGDFLPKYSGNLDIITSAAVAVAEKLAQELQVKEGVA

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786547, Length=315, Percent_Identity=54.9206349206349, Blast_Score=314, Evalue=4e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDH_MOOTA (Q2RHL2)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430620.1
- STRING:   Q2RHL2
- GeneID:   3832442
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1776
- NMPDR:   fig|264732.9.peg.1783
- eggNOG:   COG4569
- HOGENOM:   HBG300125
- OMA:   HVKNDAF
- ProtClustDB:   PRK08300
- BioCyc:   MTHE264732:MOTH_1776-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01657
- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21123
- PIRSF:   PIRSF015689
- SMART:   SM00859
- TIGRFAMs:   TIGR03215

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh

EC number: =1.2.1.10

Molecular weight: Translated: 30795; Mature: 30795

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: BINDING 265-265

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKVKVAVIGPGNIGSDLMYKILRSRHLEMALMTGIIESEGIKRARKLGIKTSIEGVKAV
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LAEDDIKIVFDATGAKPHLQHAPLLKEAGKIAIDLTPAAVGPYVVPCVNLDQVKAEPNLN
HCCCCEEEEEECCCCCCCCCCCCHHHHCCCEEEEECCCCCCCEEEECCCHHHHCCCCCCC
MVTCGGQATVPIVYAINRVAGARYAEIVACIASKSAGPGTRQNIDEFTQTTAKALEVVGG
EEEECCCCCCHHEEEHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCC
AKKGKAIIILNPAEPPIMMHNTIYVEVEKPDIEAIRASVEAMVKEIQSYVPGYRLVVPPI
CCCCCEEEEECCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEECCE
LDGNKVTAAVEVEGAGDFLPKYSGNLDIITSAAVAVAEKLAQELQVKEGVA
ECCCEEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDKVKVAVIGPGNIGSDLMYKILRSRHLEMALMTGIIESEGIKRARKLGIKTSIEGVKAV
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LAEDDIKIVFDATGAKPHLQHAPLLKEAGKIAIDLTPAAVGPYVVPCVNLDQVKAEPNLN
HCCCCEEEEEECCCCCCCCCCCCHHHHCCCEEEEECCCCCCCEEEECCCHHHHCCCCCCC
MVTCGGQATVPIVYAINRVAGARYAEIVACIASKSAGPGTRQNIDEFTQTTAKALEVVGG
EEEECCCCCCHHEEEHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCC
AKKGKAIIILNPAEPPIMMHNTIYVEVEKPDIEAIRASVEAMVKEIQSYVPGYRLVVPPI
CCCCCEEEEECCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEECCE
LDGNKVTAAVEVEGAGDFLPKYSGNLDIITSAAVAVAEKLAQELQVKEGVA
ECCCEEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA