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The map label for this gene is nuoE [H]

Identifier: 83590555

GI number: 83590555

Start: 1762741

End: 1763214

Strand: Reverse

Name: nuoE [H]

Synonym: Moth_1719

Alternate gene names: 83590555

Gene position: 1763214-1762741 (Counterclockwise)

Preceding gene: 83590556

Following gene: 83590554

Centisome position: 67.07

GC content: 55.7

Gene sequence:

>474_bases
ATGGAAACCTGTCAATGCGAAGCTAAATGGGAGGAACTTGAAAAAATCATCGACGCCCACCGGGGACAGCCGTCGGCCTT
GATCGAGGTGCTCCACCAGAGCCAGGAACTGGTAGGCTATTTGCCCCGTAATGTCCAGGTAGCAATCGCCGATGGTCTGG
GGCTATCTCTAAGCCAGGTTTACAGTGTGGTGTCCTTCTATAACCATTTTACGACCAAGCCCAAGGGCAAATACCAGGTC
TCGGTGTGCATGGGCACTGCCTGCTTTGTTAAGGGTGCGCCGGCGATACTGGAACGCCTGGAGCAGGAACTGGGAACGAA
AGTCGGCGACACCACGGCGGACGGTAGATTTACCATCAATCAGGTACGCTGCCTCGGTTGCTGCGCCCTGGGGCCGGTGA
TGACCGTCAACCAGAAGGCCCATGGCCGCTTAACCCCGGATACCGCCCTGGAGATATTAAAGGAATACCAGTAA

Upstream 100 bases:

>100_bases
TCCCGGTACGGCTCGAGGCGGTTTCGGGCAGACGGCTTATTGCAGGATGTATACCCCCTGAGTGTACCATGGCTACTCTT
GCAATGAGGAGGTTGTTCTA

Downstream 100 bases:

>100_bases
TAAGGTCTCGCCAAAATGCACGGGGGTGATGAGTTGTGATTAAGTCGATGGAAGAACTGCAGAAGTTCAAGGAAAGCCAG
TTGGAAGCCATGCAATCCCA

Product: NADH dehydrogenase (ubiquinone), 24 kDa subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E; NUO5 [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
METCQCEAKWEELEKIIDAHRGQPSALIEVLHQSQELVGYLPRNVQVAIADGLGLSLSQVYSVVSFYNHFTTKPKGKYQV
SVCMGTACFVKGAPAILERLEQELGTKVGDTTADGRFTINQVRCLGCCALGPVMTVNQKAHGRLTPDTALEILKEYQ

Sequences:

>Translated_157_residues
METCQCEAKWEELEKIIDAHRGQPSALIEVLHQSQELVGYLPRNVQVAIADGLGLSLSQVYSVVSFYNHFTTKPKGKYQV
SVCMGTACFVKGAPAILERLEQELGTKVGDTTADGRFTINQVRCLGCCALGPVMTVNQKAHGRLTPDTALEILKEYQ
>Mature_157_residues
METCQCEAKWEELEKIIDAHRGQPSALIEVLHQSQELVGYLPRNVQVAIADGLGLSLSQVYSVVSFYNHFTTKPKGKYQV
SVCMGTACFVKGAPAILERLEQELGTKVGDTTADGRFTINQVRCLGCCALGPVMTVNQKAHGRLTPDTALEILKEYQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=153, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1788621, Length=150, Percent_Identity=35.3333333333333, Blast_Score=98, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17561328, Length=149, Percent_Identity=35.5704697986577, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859877, Length=132, Percent_Identity=38.6363636363636, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355353, Length=132, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17244; Mature: 17244

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METCQCEAKWEELEKIIDAHRGQPSALIEVLHQSQELVGYLPRNVQVAIADGLGLSLSQV
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
YSVVSFYNHFTTKPKGKYQVSVCMGTACFVKGAPAILERLEQELGTKVGDTTADGRFTIN
HHHHHHHHHHCCCCCCCEEEEEEECHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEHH
QVRCLGCCALGPVMTVNQKAHGRLTPDTALEILKEYQ
HHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
METCQCEAKWEELEKIIDAHRGQPSALIEVLHQSQELVGYLPRNVQVAIADGLGLSLSQV
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
YSVVSFYNHFTTKPKGKYQVSVCMGTACFVKGAPAILERLEQELGTKVGDTTADGRFTIN
HHHHHHHHHHCCCCCCCEEEEEEECHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEHH
QVRCLGCCALGPVMTVNQKAHGRLTPDTALEILKEYQ
HHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]