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The map label for this gene is dtd

Identifier: 83590515

GI number: 83590515

Start: 1716173

End: 1716622

Strand: Reverse

Name: dtd

Synonym: Moth_1679

Alternate gene names: 83590515

Gene position: 1716622-1716173 (Counterclockwise)

Preceding gene: 83590516

Following gene: 83590514

Centisome position: 65.3

GC content: 64.22

Gene sequence:

>450_bases
ATGAGGGCGGTAGTCCAGCGGGTCAAAAAGGCCAGGGTTACGGTAGCCGGGGAAGAGATTGCGACAATCGGTCCCGGTTT
GCTCGTCTTCCTGGGGGTGGGGCAGCAGGACGGCCCGGCCGACGTGGAGTACCTGGCCGATAAAATCGCCGGCCTGCGGA
TCTTTGCCGACGAGGATGGTAAAATGAACCTGTCCGTCAGGGACACCGGCGGGGAAGTCCTGGCAGTTTCCCAGTTTACC
CTCTACGGCGACTGTCGCAAGGGCCGGCGGCCCAGTTTCACCGCCGCGGCCCCGCCGGAGCAGGCCCTTAACCTTTACCG
CCAGTTCGTTGCCGCCCTGGCCGCCCGGGGCTTGAAGGTGGCCACCGGCCGATTCCAGGCCGACATGCTGGTGGCCCTGG
AAAACGATGGCCCGGTAACCATGCTCCTGGACAGCCAGCGGCTTTTTTAA

Upstream 100 bases:

>100_bases
AGGGTAGTTCCCGGGTAAAGGAGTTACTATTATCGTGAGATGCTAATAACTATAGAAGTCGGGGTGTATTTGTGTTAAAC
TGCAGGAGAGGTGGCCACCC

Downstream 100 bases:

>100_bases
AAGTGTACGGCGGAGCCCCTCATTGGAGCTGACGCCTGTGCAAAGAGATAAAGCCAAGCCACCCCCGCCGCTTGAGCAAC
TTAAGCGCCAAGTTCGCTAG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRAVVQRVKKARVTVAGEEIATIGPGLLVFLGVGQQDGPADVEYLADKIAGLRIFADEDGKMNLSVRDTGGEVLAVSQFT
LYGDCRKGRRPSFTAAAPPEQALNLYRQFVAALAARGLKVATGRFQADMLVALENDGPVTMLLDSQRLF

Sequences:

>Translated_149_residues
MRAVVQRVKKARVTVAGEEIATIGPGLLVFLGVGQQDGPADVEYLADKIAGLRIFADEDGKMNLSVRDTGGEVLAVSQFT
LYGDCRKGRRPSFTAAAPPEQALNLYRQFVAALAARGLKVATGRFQADMLVALENDGPVTMLLDSQRLF
>Mature_149_residues
MRAVVQRVKKARVTVAGEEIATIGPGLLVFLGVGQQDGPADVEYLADKIAGLRIFADEDGKMNLSVRDTGGEVLAVSQFT
LYGDCRKGRRPSFTAAAPPEQALNLYRQFVAALAARGLKVATGRFQADMLVALENDGPVTMLLDSQRLF

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=46.3087248322148, Blast_Score=119, Evalue=1e-27,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=50.3496503496504, Blast_Score=138, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI115533292, Length=150, Percent_Identity=43.3333333333333, Blast_Score=109, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6319982, Length=150, Percent_Identity=36.6666666666667, Blast_Score=103, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=48.9795918367347, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_MOOTA (Q2RHV8)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430524.1
- HSSP:   O66742
- ProteinModelPortal:   Q2RHV8
- SMR:   Q2RHV8
- STRING:   Q2RHV8
- GeneID:   3831950
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1679
- NMPDR:   fig|264732.9.peg.1677
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   Q2RHV8
- ProtClustDB:   PRK05273
- BioCyc:   MTHE264732:MOTH_1679-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16011; Mature: 16011

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVVQRVKKARVTVAGEEIATIGPGLLVFLGVGQQDGPADVEYLADKIAGLRIFADEDG
CHHHHHHHHHHEEEECCCCHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCCEEEEECCCC
KMNLSVRDTGGEVLAVSQFTLYGDCRKGRRPSFTAAAPPEQALNLYRQFVAALAARGLKV
EEEEEEECCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEE
ATGRFQADMLVALENDGPVTMLLDSQRLF
ECCCCCEEEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MRAVVQRVKKARVTVAGEEIATIGPGLLVFLGVGQQDGPADVEYLADKIAGLRIFADEDG
CHHHHHHHHHHEEEECCCCHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCCEEEEECCCC
KMNLSVRDTGGEVLAVSQFTLYGDCRKGRRPSFTAAAPPEQALNLYRQFVAALAARGLKV
EEEEEEECCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEE
ATGRFQADMLVALENDGPVTMLLDSQRLF
ECCCCCEEEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA