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The map label for this gene is hsdM [C]

Identifier: 83590508

GI number: 83590508

Start: 1708647

End: 1710197

Strand: Reverse

Name: hsdM [C]

Synonym: Moth_1672

Alternate gene names: 83590508

Gene position: 1710197-1708647 (Counterclockwise)

Preceding gene: 83590509

Following gene: 83590507

Centisome position: 65.06

GC content: 49.9

Gene sequence:

>1551_bases
ATGACGGAAAACACCAATATGGATCTTAGCACCCTGGAAAACTGGCTATGGGAGGCAGCCTGTGTAATTCGCGGTGCAGT
TGATGCTCCCAAGTATAAGGATTACATATTGCCCCTGATCTTCCTAAAACGCCTGTCAGACGTATTTGAAGATGAAATAG
CCAGGCTGGCCGAAGAGATATTTGATAGTATAGAGGAAGCCCTGAAACAGGTTGAGGAAGACCATGCCCTGGTGCGTTTT
TATATCCCTCCCCAGGCCCGCTGGGATGCTATTTCCCGGCAGACTACCAACATAGGCGAATACCTTACCAGTGCCGTGCG
GGCTGTAGCCCGGGAGAATCCTAAACTGCACGGCATCTTTGAGAACATTGACTTCAACGCCCAGATGGCCGGCCAGCCGG
TTATTGATAACGACCGTCTCTATAACCTGATTCAAGTCCTTTCCCGCCATCGTTTAGGGTTAAAAGATGTAGAAGTAGAC
ATCCTGGGCCGGGCTTATGAATACCTGCTGCGCAAATTCGCCGAGGGCCAGGGCCAGAGTGCCGGCGAATTCTATACCCC
CCGGGAAGTTACCTGGCTAATGGCTTATCTACTGGAGCCCCGACCAGGAGATGAGATCTATGACCCGGCCTGCGGTTCCG
GCGGCCTGTTGATCAAAAGCGTATTAGCTCTTAAGGAAACTTATGGTGATGACCCTAGAATAGCACCGGTTAAGATTTAT
GGTCAGGAAATCCTTTATACCACCTTCGCTATGGCCAAAATGAACGCCTTTATCCATGACCTGGAGGCTGATATTCGCCT
GGGCGATACAATGGCCCGGCCGGCCTTTACCAATCCCGACGGTTCTTTGCGTACCTTTGATAAGGTCACTGCTAATCCCA
TGTGGAACCAGAAATTCCCCCTTCCCCTATATGAAGAAGACCCCTTTGATCGGTTTAAGTTTGGCGGCATTCCGCCGGCA
TCAAGCGCTGACTGGGGCTGGATCCAGCATATGTTTGCCTCCCTGAAAGAAGGGGGCAAAATGGCCGTGGTCCTGGATAC
CGGTTCAGTCTCCCGGGGCAGCGGTAACCAGGGCTCCAACCGGGAGAGGGACATTCGTAAAGTCTTTGTTGAAAACGACC
TGGTAGAGTGCGTTATCTTGTTGCCGGAAAATATGTTCTATAATACTACCGCCCCGGGTATAATCATGGTCATAAATAAG
GCCAAAAAGCATCCAGCGGAGATTTTATTAATCAACGCCTCTAAACTGTTCACCAAAGGGCGCCCCAAGAATTACATGGA
AGATGAGCATATAAAGCAGGTCTATAGCATCTACCGGGAATGGCGGGAAGAAGAGGGATTAAGCAAAATAATTCCAGTAG
AAGAAGCAGCCCGCAATGACTACAATCTTAGCCCTTCTCGCTATGTATCTATTAATGGCAAAGAAGAATACCGGCCCATA
GAGGAAATATTGGTCGAGCTGGCCGAGGTCGAGGAAGAACGGCAAGCCGTAGATAAGGAACTGAATGATATCCTGGGTAA
GTTGGGTTTCGGAGGCTGGCTGAATGGGTAA

Upstream 100 bases:

>100_bases
AAAGAAAGAAAAAACAGCGAGTAAAACAGTTGCCTAACTTGATAAAGAAGGTAAGTGGGAATGAACCATATAATTCCCAT
GTAATAACGGAGGAAAGGCC

Downstream 100 bases:

>100_bases
GGAAGTTAATGAGGTGAAGGAAGGATATAAGGAGACGGAGATTGGGGTGCTGCCGGAGGATTGGGAAGTGGTGAGGCTGG
GGAAAGTTTTTGAAGAGGTA

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.MjaXP [H]

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MTENTNMDLSTLENWLWEAACVIRGAVDAPKYKDYILPLIFLKRLSDVFEDEIARLAEEIFDSIEEALKQVEEDHALVRF
YIPPQARWDAISRQTTNIGEYLTSAVRAVARENPKLHGIFENIDFNAQMAGQPVIDNDRLYNLIQVLSRHRLGLKDVEVD
ILGRAYEYLLRKFAEGQGQSAGEFYTPREVTWLMAYLLEPRPGDEIYDPACGSGGLLIKSVLALKETYGDDPRIAPVKIY
GQEILYTTFAMAKMNAFIHDLEADIRLGDTMARPAFTNPDGSLRTFDKVTANPMWNQKFPLPLYEEDPFDRFKFGGIPPA
SSADWGWIQHMFASLKEGGKMAVVLDTGSVSRGSGNQGSNRERDIRKVFVENDLVECVILLPENMFYNTTAPGIIMVINK
AKKHPAEILLINASKLFTKGRPKNYMEDEHIKQVYSIYREWREEEGLSKIIPVEEAARNDYNLSPSRYVSINGKEEYRPI
EEILVELAEVEEERQAVDKELNDILGKLGFGGWLNG

Sequences:

>Translated_516_residues
MTENTNMDLSTLENWLWEAACVIRGAVDAPKYKDYILPLIFLKRLSDVFEDEIARLAEEIFDSIEEALKQVEEDHALVRF
YIPPQARWDAISRQTTNIGEYLTSAVRAVARENPKLHGIFENIDFNAQMAGQPVIDNDRLYNLIQVLSRHRLGLKDVEVD
ILGRAYEYLLRKFAEGQGQSAGEFYTPREVTWLMAYLLEPRPGDEIYDPACGSGGLLIKSVLALKETYGDDPRIAPVKIY
GQEILYTTFAMAKMNAFIHDLEADIRLGDTMARPAFTNPDGSLRTFDKVTANPMWNQKFPLPLYEEDPFDRFKFGGIPPA
SSADWGWIQHMFASLKEGGKMAVVLDTGSVSRGSGNQGSNRERDIRKVFVENDLVECVILLPENMFYNTTAPGIIMVINK
AKKHPAEILLINASKLFTKGRPKNYMEDEHIKQVYSIYREWREEEGLSKIIPVEEAARNDYNLSPSRYVSINGKEEYRPI
EEILVELAEVEEERQAVDKELNDILGKLGFGGWLNG
>Mature_515_residues
TENTNMDLSTLENWLWEAACVIRGAVDAPKYKDYILPLIFLKRLSDVFEDEIARLAEEIFDSIEEALKQVEEDHALVRFY
IPPQARWDAISRQTTNIGEYLTSAVRAVARENPKLHGIFENIDFNAQMAGQPVIDNDRLYNLIQVLSRHRLGLKDVEVDI
LGRAYEYLLRKFAEGQGQSAGEFYTPREVTWLMAYLLEPRPGDEIYDPACGSGGLLIKSVLALKETYGDDPRIAPVKIYG
QEILYTTFAMAKMNAFIHDLEADIRLGDTMARPAFTNPDGSLRTFDKVTANPMWNQKFPLPLYEEDPFDRFKFGGIPPAS
SADWGWIQHMFASLKEGGKMAVVLDTGSVSRGSGNQGSNRERDIRKVFVENDLVECVILLPENMFYNTTAPGIIMVINKA
KKHPAEILLINASKLFTKGRPKNYMEDEHIKQVYSIYREWREEEGLSKIIPVEEAARNDYNLSPSRYVSINGKEEYRPIE
EILVELAEVEEERQAVDKELNDILGKLGFGGWLNG

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=429, Percent_Identity=22.3776223776224, Blast_Score=89, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 58693; Mature: 58562

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENTNMDLSTLENWLWEAACVIRGAVDAPKYKDYILPLIFLKRLSDVFEDEIARLAEEI
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDSIEEALKQVEEDHALVRFYIPPQARWDAISRQTTNIGEYLTSAVRAVARENPKLHGIF
HHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
ENIDFNAQMAGQPVIDNDRLYNLIQVLSRHRLGLKDVEVDILGRAYEYLLRKFAEGQGQS
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
AGEFYTPREVTWLMAYLLEPRPGDEIYDPACGSGGLLIKSVLALKETYGDDPRIAPVKIY
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEC
GQEILYTTFAMAKMNAFIHDLEADIRLGDTMARPAFTNPDGSLRTFDKVTANPMWNQKFP
CHHHHHHHHHHHHHHHHHHHHHHHHEECCHHCCCCCCCCCCCCEEHHHHHCCCCCCCCCC
LPLYEEDPFDRFKFGGIPPASSADWGWIQHMFASLKEGGKMAVVLDTGSVSRGSGNQGSN
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
RERDIRKVFVENDLVECVILLPENMFYNTTAPGIIMVINKAKKHPAEILLINASKLFTKG
HHHHHHHHHHHCCHHEEEEECCCCCEECCCCCCEEEEEECCCCCCCEEEEEEHHHHHHCC
RPKNYMEDEHIKQVYSIYREWREEEGLSKIIPVEEAARNDYNLSPSRYVSINGKEEYRPI
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHCCCCCCCCCEEEEECCHHHCCHH
EEILVELAEVEEERQAVDKELNDILGKLGFGGWLNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TENTNMDLSTLENWLWEAACVIRGAVDAPKYKDYILPLIFLKRLSDVFEDEIARLAEEI
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDSIEEALKQVEEDHALVRFYIPPQARWDAISRQTTNIGEYLTSAVRAVARENPKLHGIF
HHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
ENIDFNAQMAGQPVIDNDRLYNLIQVLSRHRLGLKDVEVDILGRAYEYLLRKFAEGQGQS
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
AGEFYTPREVTWLMAYLLEPRPGDEIYDPACGSGGLLIKSVLALKETYGDDPRIAPVKIY
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEC
GQEILYTTFAMAKMNAFIHDLEADIRLGDTMARPAFTNPDGSLRTFDKVTANPMWNQKFP
CHHHHHHHHHHHHHHHHHHHHHHHHEECCHHCCCCCCCCCCCCEEHHHHHCCCCCCCCCC
LPLYEEDPFDRFKFGGIPPASSADWGWIQHMFASLKEGGKMAVVLDTGSVSRGSGNQGSN
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
RERDIRKVFVENDLVECVILLPENMFYNTTAPGIIMVINKAKKHPAEILLINASKLFTKG
HHHHHHHHHHHCCHHEEEEECCCCCEECCCCCCEEEEEECCCCCCCEEEEEEHHHHHHCC
RPKNYMEDEHIKQVYSIYREWREEEGLSKIIPVEEAARNDYNLSPSRYVSINGKEEYRPI
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHCCCCCCCCCEEEEECCHHHCCHH
EEILVELAEVEEERQAVDKELNDILGKLGFGGWLNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]