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The map label for this gene is cobB [H]

Identifier: 83590464

GI number: 83590464

Start: 1663629

End: 1664981

Strand: Reverse

Name: cobB [H]

Synonym: Moth_1628

Alternate gene names: 83590464

Gene position: 1664981-1663629 (Counterclockwise)

Preceding gene: 83590465

Following gene: 83590463

Centisome position: 63.34

GC content: 61.86

Gene sequence:

>1353_bases
ATGCGCCTGGTAATTGCGGCGCCCCACGGCCGTTCGGGCAAGACAACCATTACTATAGGCTTAATAGCCGCTTTGAGGCA
AAAGGGTCTGGTGATCCAGCCCTTCAAAAAGGGGCCTGATTTCATCGACCCGGGGTGGTTGAGCCTGGTGGCCGGTCGCC
CCTGCCGCAATCTTGACCTCTATTTCTTATCACCGGAAAAGCTCCGGCTGCACTTTGCCGCCAGTTGCCGGGGAGCCGAT
GTGGGTTTGGTGGAAGGGGCCATGGGGCTCTTTGACGGCCTGGATCTGGAGGGCAGTGATAGTACTGCTGCCGTAGCCAG
GGCCCTCATGGCTCCGGTGGTGCTGGTAATTGACGCTACCCGTATGACCAGGAGCGCTGCCGCCCTGGTGCGAGGCTTCC
AGAATTTTGACCCCGGGGTAAGCATCGCCGGGGTAATCCTGAACCAGGTGGCCCGCGCCCGCCACGAGGATATCCTGCGC
CGCTCCATTGAACACTATACCGGCCTGCCGGTGCTGGGGGCCCTGCCCAAAAAGAAAGACTTCGGTATACCCGACCGCCA
CCTGGGCCTGATCCCGGCGGCAGAAAACGAACGCCTCCATGTAGCCCTGGAGGCTACGGGTAAAGCCATCGCAGCGGCAG
TCGACCTGGACGCCCTGCTGGCCATTGCCAGCCGGGCCCCGGAGCTTACGGCACCGGAACAGGAAAACCGGCCGGCCCCA
CGCCGGGTACGCCTGGGCGTCTTCCAGGATCGCGTTTTTACTTTTTATTACCCGGAAAACCTGGAGGCCCTGGCTGCCGC
CGGGGCCGAACTGGTAAAGATTGACAGCCTGGCAGATGAGAAATTACCGGACGTCCAGGGGCTCTATCTCGGCGGCGGTT
TCCCCGAGGTTTTTGCCCCTCAACTGGAAGCCAACAGGTCTTTGCGGCGGGAGGTTAAGGAAGCCGTGGCTGCCGGCATG
CCGGTCTATGCCGAGTGCGGCGGCCTGATGTACCTGGCCCGGAGGCTCAATTACCGGGGACGCTGGTATGAAATGTGCGG
TGCCCTGCCATTGGACGTGACAATGTCTTCCTGCCCCCAGGGCCACGGCTATACAGCCATGTACGTCGAGGGCGATAGCC
CCTTCCTGACCCGGGGCAGTACTATCCGGGGTCATGAGTTCCACCACTCGCGGGTAATAAACCTGGAACGCCGGGAGGTA
AACTTCCTTTACCGGGTACGCCGGGGCTATGGCATCGACGGCCAGGTGGACGGTATTCTTTACCGGCAGGTCCTGGCAGG
GTATAATCATTTATACGCCCCGTCCAGCCCCGAGTGGGCGCCCAACCTGGTGGCCCTGGCGGCGGGGAACTAA

Upstream 100 bases:

>100_bases
TCAAGGCCGTAGGGGCTAGCCCGGTAGCAGACATTTTTGATAACCATTTCCCCTTTGCCGGCCTACGCCGGGACCTGCAC
CTGCGGTAGGAGGTGGACCC

Downstream 100 bases:

>100_bases
ATACGGTAAGCAGCATTGTAGGGAATTGAGGAGGTCCCGGCATGACCATAGGTGAGAAACTAAAAAAGCTAAGGGAAGAT
AGGGGAATACCCCTGGAGGA

Product: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) / cobyrinate a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MRLVIAAPHGRSGKTTITIGLIAALRQKGLVIQPFKKGPDFIDPGWLSLVAGRPCRNLDLYFLSPEKLRLHFAASCRGAD
VGLVEGAMGLFDGLDLEGSDSTAAVARALMAPVVLVIDATRMTRSAAALVRGFQNFDPGVSIAGVILNQVARARHEDILR
RSIEHYTGLPVLGALPKKKDFGIPDRHLGLIPAAENERLHVALEATGKAIAAAVDLDALLAIASRAPELTAPEQENRPAP
RRVRLGVFQDRVFTFYYPENLEALAAAGAELVKIDSLADEKLPDVQGLYLGGGFPEVFAPQLEANRSLRREVKEAVAAGM
PVYAECGGLMYLARRLNYRGRWYEMCGALPLDVTMSSCPQGHGYTAMYVEGDSPFLTRGSTIRGHEFHHSRVINLERREV
NFLYRVRRGYGIDGQVDGILYRQVLAGYNHLYAPSSPEWAPNLVALAAGN

Sequences:

>Translated_450_residues
MRLVIAAPHGRSGKTTITIGLIAALRQKGLVIQPFKKGPDFIDPGWLSLVAGRPCRNLDLYFLSPEKLRLHFAASCRGAD
VGLVEGAMGLFDGLDLEGSDSTAAVARALMAPVVLVIDATRMTRSAAALVRGFQNFDPGVSIAGVILNQVARARHEDILR
RSIEHYTGLPVLGALPKKKDFGIPDRHLGLIPAAENERLHVALEATGKAIAAAVDLDALLAIASRAPELTAPEQENRPAP
RRVRLGVFQDRVFTFYYPENLEALAAAGAELVKIDSLADEKLPDVQGLYLGGGFPEVFAPQLEANRSLRREVKEAVAAGM
PVYAECGGLMYLARRLNYRGRWYEMCGALPLDVTMSSCPQGHGYTAMYVEGDSPFLTRGSTIRGHEFHHSRVINLERREV
NFLYRVRRGYGIDGQVDGILYRQVLAGYNHLYAPSSPEWAPNLVALAAGN
>Mature_450_residues
MRLVIAAPHGRSGKTTITIGLIAALRQKGLVIQPFKKGPDFIDPGWLSLVAGRPCRNLDLYFLSPEKLRLHFAASCRGAD
VGLVEGAMGLFDGLDLEGSDSTAAVARALMAPVVLVIDATRMTRSAAALVRGFQNFDPGVSIAGVILNQVARARHEDILR
RSIEHYTGLPVLGALPKKKDFGIPDRHLGLIPAAENERLHVALEATGKAIAAAVDLDALLAIASRAPELTAPEQENRPAP
RRVRLGVFQDRVFTFYYPENLEALAAAGAELVKIDSLADEKLPDVQGLYLGGGFPEVFAPQLEANRSLRREVKEAVAAGM
PVYAECGGLMYLARRLNYRGRWYEMCGALPLDVTMSSCPQGHGYTAMYVEGDSPFLTRGSTIRGHEFHHSRVINLERREV
NFLYRVRRGYGIDGQVDGILYRQVLAGYNHLYAPSSPEWAPNLVALAAGN

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 49001; Mature: 49001

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVIAAPHGRSGKTTITIGLIAALRQKGLVIQPFKKGPDFIDPGWLSLVAGRPCRNLDL
CEEEEECCCCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHCCCCCCCCEE
YFLSPEKLRLHFAASCRGADVGLVEGAMGLFDGLDLEGSDSTAAVARALMAPVVLVIDAT
EEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCEEEEEECH
RMTRSAAALVRGFQNFDPGVSIAGVILNQVARARHEDILRRSIEHYTGLPVLGALPKKKD
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCC
FGIPDRHLGLIPAAENERLHVALEATGKAIAAAVDLDALLAIASRAPELTAPEQENRPAP
CCCCCCCEEEEECCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
RRVRLGVFQDRVFTFYYPENLEALAAAGAELVKIDSLADEKLPDVQGLYLGGGFPEVFAP
CEEEEEEEECCEEEEECCCCHHHHHHCCCCEEEEHHHHHCCCCCCCEEEECCCCHHHHCC
QLEANRSLRREVKEAVAAGMPVYAECGGLMYLARRLNYRGRWYEMCGALPLDVTMSSCPQ
HHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHCCCCCHHHHHCCCEEEEEHHCCCC
GHGYTAMYVEGDSPFLTRGSTIRGHEFHHSRVINLERREVNFLYRVRRGYGIDGQVDGIL
CCCEEEEEEECCCCEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCHHHH
YRQVLAGYNHLYAPSSPEWAPNLVALAAGN
HHHHHHCCCCCCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MRLVIAAPHGRSGKTTITIGLIAALRQKGLVIQPFKKGPDFIDPGWLSLVAGRPCRNLDL
CEEEEECCCCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHCCCCCCCCEE
YFLSPEKLRLHFAASCRGADVGLVEGAMGLFDGLDLEGSDSTAAVARALMAPVVLVIDAT
EEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCEEEEEECH
RMTRSAAALVRGFQNFDPGVSIAGVILNQVARARHEDILRRSIEHYTGLPVLGALPKKKD
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCC
FGIPDRHLGLIPAAENERLHVALEATGKAIAAAVDLDALLAIASRAPELTAPEQENRPAP
CCCCCCCEEEEECCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
RRVRLGVFQDRVFTFYYPENLEALAAAGAELVKIDSLADEKLPDVQGLYLGGGFPEVFAP
CEEEEEEEECCEEEEECCCCHHHHHHCCCCEEEEHHHHHCCCCCCCEEEECCCCHHHHCC
QLEANRSLRREVKEAVAAGMPVYAECGGLMYLARRLNYRGRWYEMCGALPLDVTMSSCPQ
HHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHCCCCCHHHHHCCCEEEEEHHCCCC
GHGYTAMYVEGDSPFLTRGSTIRGHEFHHSRVINLERREVNFLYRVRRGYGIDGQVDGIL
CCCEEEEEEECCCCEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCHHHH
YRQVLAGYNHLYAPSSPEWAPNLVALAAGN
HHHHHHCCCCCCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA