Click here to switch to the map view.

The map label for this gene is trpB1 [H]

Identifier: 83590184

GI number: 83590184

Start: 1383317

End: 1384522

Strand: Reverse

Name: trpB1 [H]

Synonym: Moth_1337

Alternate gene names: 83590184

Gene position: 1384522-1383317 (Counterclockwise)

Preceding gene: 83590185

Following gene: 83590183

Centisome position: 52.67

GC content: 58.87

Gene sequence:

>1206_bases
ATGACATTACCAGATAAACAGGGTCATTTTGGCCCCTATGGCGGGCGGTTTGTACCCGAAACCCTCATGCCGGCCCTGGA
AGAGATAGAACAGGCTTACCGGGAAGCCTCCCGGGATAAAGAATTTCAAAAGGAACTTCAGTATTATCTTCAGCAATACG
CCGGCAGGCCGACTCCCTTGTATTACGCGGCCAACCTTACCCGTCACCTGGGCGGGGCCAGGATTTACCTGAAAAGGGAG
GATTTAAATCATACCGGTTCCCACAAGTTAAATAACGCCTTGGGCCAGGCATTGCTTGCCCGGCGTATGGGCAAGAAACG
CCTCATTGCTGAAACAGGAGCCGGCCAGCACGGGGTGGCTGCGGCTACAGCGGCGGCCCTCCTGGATATGGAATGCGTCG
TTTATATGGGTGCCGAAGACACCCGCCGTCAGGCCTTGAATGTCTTTCGTATGGAACTCCTGGGGGCCAGGGTGGTCCCG
GTGACAGCCGGTAGCGCCACTTTAAAGGACGCCATCAACGAAGCCCTGCGGGACTGGGTTACCAACGTCCGCACCACATA
TTACCTCCTTGGTTCGGTGACCGGTCCCCACCCGTTCCCCATGATGGTACGGGACTTCCAATCTGTCATCGGCAGAGAGG
CCAGGGAGCAAATCCTGGCCGCAGCCGGGCGCCTGCCGGATCACCTGGTAGCCTGCGTCGGCGGGGGCAGTAATGCCATG
GGACTTTTTTACCCCTTCCTCGAAGAAACGGGGGTCAGAATGTGGGGCGCTGAAGCCGCCGGGCTGGGACTGGAGACCGG
CCGCCACGCCGCTTCTTTAACCGCGGGTCGCCCCGGTGTCTTTCAGGGTGCCTACAGTTACCTGGTCCAGGATAAAAACG
GCCAGATCGAGCCGGTGTATTCTGTCTCGGCCGGCCTGGATTACCCCGGCGTCGGGCCGGAGCACAGCTACCTCAAAGAT
AGTGGCCGGGCTACCTACACAGCTATAACTGATACTGAAGCCCTGGAGGCCTTTCAACTCCTGAGCCGTACAGAGGGTAT
TATCCCCGCCCTGGAGAGCTCCCACGCCGTAGCCCTGGCCATGAAAATGGCCCCCGGCTTAAAGCCGGAAGAGATTATGA
TCATCAACCTCTCCGGCCGGGGAGATAAAGACGTCCAGCAGGTGGCCGCCATCCTCAAGGGAGGGAGCTCCAACCATGGG
TGTTGA

Upstream 100 bases:

>100_bases
CCCGGATAGCCGCCTTTCTGGAGGCAGTGAGGAAAGCTGAGGAGCACCATGTGCGCCCAACCGCCAGCAGTTGCTGTACG
GGATTGAAGGGGGATTTTTG

Downstream 100 bases:

>100_bases
AAGAATAACTGCTGCCTTTGCCGCCCGGAAAAAAGAGGGACGCAAAGCCCTCATCGTCTATCTCTGTGCCGGCGACCCTT
CCCTGGAGGTTACCGGGCAA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTLPDKQGHFGPYGGRFVPETLMPALEEIEQAYREASRDKEFQKELQYYLQQYAGRPTPLYYAANLTRHLGGARIYLKRE
DLNHTGSHKLNNALGQALLARRMGKKRLIAETGAGQHGVAAATAAALLDMECVVYMGAEDTRRQALNVFRMELLGARVVP
VTAGSATLKDAINEALRDWVTNVRTTYYLLGSVTGPHPFPMMVRDFQSVIGREAREQILAAAGRLPDHLVACVGGGSNAM
GLFYPFLEETGVRMWGAEAAGLGLETGRHAASLTAGRPGVFQGAYSYLVQDKNGQIEPVYSVSAGLDYPGVGPEHSYLKD
SGRATYTAITDTEALEAFQLLSRTEGIIPALESSHAVALAMKMAPGLKPEEIMIINLSGRGDKDVQQVAAILKGGSSNHG
C

Sequences:

>Translated_401_residues
MTLPDKQGHFGPYGGRFVPETLMPALEEIEQAYREASRDKEFQKELQYYLQQYAGRPTPLYYAANLTRHLGGARIYLKRE
DLNHTGSHKLNNALGQALLARRMGKKRLIAETGAGQHGVAAATAAALLDMECVVYMGAEDTRRQALNVFRMELLGARVVP
VTAGSATLKDAINEALRDWVTNVRTTYYLLGSVTGPHPFPMMVRDFQSVIGREAREQILAAAGRLPDHLVACVGGGSNAM
GLFYPFLEETGVRMWGAEAAGLGLETGRHAASLTAGRPGVFQGAYSYLVQDKNGQIEPVYSVSAGLDYPGVGPEHSYLKD
SGRATYTAITDTEALEAFQLLSRTEGIIPALESSHAVALAMKMAPGLKPEEIMIINLSGRGDKDVQQVAAILKGGSSNHG
C
>Mature_400_residues
TLPDKQGHFGPYGGRFVPETLMPALEEIEQAYREASRDKEFQKELQYYLQQYAGRPTPLYYAANLTRHLGGARIYLKRED
LNHTGSHKLNNALGQALLARRMGKKRLIAETGAGQHGVAAATAAALLDMECVVYMGAEDTRRQALNVFRMELLGARVVPV
TAGSATLKDAINEALRDWVTNVRTTYYLLGSVTGPHPFPMMVRDFQSVIGREAREQILAAAGRLPDHLVACVGGGSNAMG
LFYPFLEETGVRMWGAEAAGLGLETGRHAASLTAGRPGVFQGAYSYLVQDKNGQIEPVYSVSAGLDYPGVGPEHSYLKDS
GRATYTAITDTEALEAFQLLSRTEGIIPALESSHAVALAMKMAPGLKPEEIMIINLSGRGDKDVQQVAAILKGGSSNHGC

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=386, Percent_Identity=56.4766839378238, Blast_Score=447, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=59.375, Blast_Score=478, Evalue=1e-136,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43355; Mature: 43224

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPDKQGHFGPYGGRFVPETLMPALEEIEQAYREASRDKEFQKELQYYLQQYAGRPTPL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCE
YYAANLTRHLGGARIYLKREDLNHTGSHKLNNALGQALLARRMGKKRLIAETGAGQHGVA
EEHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHH
AATAAALLDMECVVYMGAEDTRRQALNVFRMELLGARVVPVTAGSATLKDAINEALRDWV
HHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHH
TNVRTTYYLLGSVTGPHPFPMMVRDFQSVIGREAREQILAAAGRLPDHLVACVGGGSNAM
HHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCH
GLFYPFLEETGVRMWGAEAAGLGLETGRHAASLTAGRPGVFQGAYSYLVQDKNGQIEPVY
HHHHHHHHHCCCEEECCHHCCCCCCCCCCHHHCCCCCCCHHHHHHHHHEECCCCCCCEEE
SVSAGLDYPGVGPEHSYLKDSGRATYTAITDTEALEAFQLLSRTEGIIPALESSHAVALA
EEECCCCCCCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEEEH
MKMAPGLKPEEIMIINLSGRGDKDVQQVAAILKGGSSNHGC
HHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TLPDKQGHFGPYGGRFVPETLMPALEEIEQAYREASRDKEFQKELQYYLQQYAGRPTPL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCE
YYAANLTRHLGGARIYLKREDLNHTGSHKLNNALGQALLARRMGKKRLIAETGAGQHGVA
EEHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHH
AATAAALLDMECVVYMGAEDTRRQALNVFRMELLGARVVPVTAGSATLKDAINEALRDWV
HHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHH
TNVRTTYYLLGSVTGPHPFPMMVRDFQSVIGREAREQILAAAGRLPDHLVACVGGGSNAM
HHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCH
GLFYPFLEETGVRMWGAEAAGLGLETGRHAASLTAGRPGVFQGAYSYLVQDKNGQIEPVY
HHHHHHHHHCCCEEECCHHCCCCCCCCCCHHHCCCCCCCHHHHHHHHHEECCCCCCCEEE
SVSAGLDYPGVGPEHSYLKDSGRATYTAITDTEALEAFQLLSRTEGIIPALESSHAVALA
EEECCCCCCCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEEEH
MKMAPGLKPEEIMIINLSGRGDKDVQQVAAILKGGSSNHGC
HHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]