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The map label for this gene is trpA [H]

Identifier: 83590183

GI number: 83590183

Start: 1382545

End: 1383327

Strand: Reverse

Name: trpA [H]

Synonym: Moth_1336

Alternate gene names: 83590183

Gene position: 1383327-1382545 (Counterclockwise)

Preceding gene: 83590184

Following gene: 83590182

Centisome position: 52.62

GC content: 61.56

Gene sequence:

>783_bases
ATGGGTGTTGAAAGAATAACTGCTGCCTTTGCCGCCCGGAAAAAAGAGGGACGCAAAGCCCTCATCGTCTATCTCTGTGC
CGGCGACCCTTCCCTGGAGGTTACCGGGCAAGCTGTCAGGGAACTGGCTGGCGCCGGGGTGGACCTCATTGAGCTGGGGG
TACCCTTTTCTGACCCCGTGGCCGATGGTCCGGTCATCCAGGCTGCCAGCAAGCGTGCCCTTGCCGCCGGGGTAACCCTG
CCCGAAATCCTGGAATTGGTAAAGAGCCTGCGCTCGGGGTTGGCTGTCCCCTTGATCCTCATGAGCTACTATAACCCTTT
GCTGCAATATGGACTGGAACGGTTAACTGCCGATCTGGCCGCTGCCGGGGTGGATGGTTTGATTGTACCCGATCTGCCCC
TGGAAGAAAACCCACCTTTAAGACAAACCCTGGAACCGGCGGGGCTGGCCCTGATTCCCCTGGTGGCCCCGACGACCCCC
GGGGAACGTTTGGCCCGGATTGCCGCCACAGCCCGGGGATTTATCTACTGCGTTTCCCTTACCGGGGTAACAGGCGTCCG
GGAAGGCTTGCCGCCGGGAATAGACGAGTACCTGGCAGGGGTGCGGGCGGTAACTGACCTGCCCCTGGGAATAGGTTTCG
GCATCGGCAGTCCCGACCAGGCCAGGCTCCTGGCCCCTATGGGCGACGGCATTATTGTCGGCAGCGCCCTGGTCGACGTC
CTGTATCAAGAAGGCTTACCGGCCGCCCTCCGGCTGGTAGAAAGGCTCCGGCACGCTTTATAG

Upstream 100 bases:

>100_bases
GGCTTAAAGCCGGAAGAGATTATGATCATCAACCTCTCCGGCCGGGGAGATAAAGACGTCCAGCAGGTGGCCGCCATCCT
CAAGGGAGGGAGCTCCAACC

Downstream 100 bases:

>100_bases
AATAACCAGATTGCCCCTTGCCAGGAGGGGGCAGCTATGCTATAGTCTAAATGTAGTACAGTAGGATAACACTGCAGGGT
TATCTAAAATGGTAGGACGG

Product: tryptophan synthase, alpha chain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MGVERITAAFAARKKEGRKALIVYLCAGDPSLEVTGQAVRELAGAGVDLIELGVPFSDPVADGPVIQAASKRALAAGVTL
PEILELVKSLRSGLAVPLILMSYYNPLLQYGLERLTADLAAAGVDGLIVPDLPLEENPPLRQTLEPAGLALIPLVAPTTP
GERLARIAATARGFIYCVSLTGVTGVREGLPPGIDEYLAGVRAVTDLPLGIGFGIGSPDQARLLAPMGDGIIVGSALVDV
LYQEGLPAALRLVERLRHAL

Sequences:

>Translated_260_residues
MGVERITAAFAARKKEGRKALIVYLCAGDPSLEVTGQAVRELAGAGVDLIELGVPFSDPVADGPVIQAASKRALAAGVTL
PEILELVKSLRSGLAVPLILMSYYNPLLQYGLERLTADLAAAGVDGLIVPDLPLEENPPLRQTLEPAGLALIPLVAPTTP
GERLARIAATARGFIYCVSLTGVTGVREGLPPGIDEYLAGVRAVTDLPLGIGFGIGSPDQARLLAPMGDGIIVGSALVDV
LYQEGLPAALRLVERLRHAL
>Mature_259_residues
GVERITAAFAARKKEGRKALIVYLCAGDPSLEVTGQAVRELAGAGVDLIELGVPFSDPVADGPVIQAASKRALAAGVTLP
EILELVKSLRSGLAVPLILMSYYNPLLQYGLERLTADLAAAGVDGLIVPDLPLEENPPLRQTLEPAGLALIPLVAPTTPG
ERLARIAATARGFIYCVSLTGVTGVREGLPPGIDEYLAGVRAVTDLPLGIGFGIGSPDQARLLAPMGDGIIVGSALVDVL
YQEGLPAALRLVERLRHAL

Specific function: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate [H]

COG id: COG0159

COG function: function code E; Tryptophan synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpA family [H]

Homologues:

Organism=Escherichia coli, GI1787514, Length=259, Percent_Identity=35.1351351351351, Blast_Score=140, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6321412, Length=237, Percent_Identity=45.1476793248945, Blast_Score=214, Evalue=1e-56,

Paralogues:

None

Copy number: 280 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR018204
- InterPro:   IPR002028 [H]

Pfam domain/function: PF00290 Trp_syntA [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 27034; Mature: 26903

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00167 TRP_SYNTHASE_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVERITAAFAARKKEGRKALIVYLCAGDPSLEVTGQAVRELAGAGVDLIELGVPFSDPV
CCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEECHHHHHHHHHCCCCEEEECCCCCCCC
ADGPVIQAASKRALAAGVTLPEILELVKSLRSGLAVPLILMSYYNPLLQYGLERLTADLA
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGVDGLIVPDLPLEENPPLRQTLEPAGLALIPLVAPTTPGERLARIAATARGFIYCVSL
HHCCCCEECCCCCCCCCCCHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEEEEE
TGVTGVREGLPPGIDEYLAGVRAVTDLPLGIGFGIGSPDQARLLAPMGDGIIVGSALVDV
CCCHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCEEHHHHHHHH
LYQEGLPAALRLVERLRHAL
HHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
GVERITAAFAARKKEGRKALIVYLCAGDPSLEVTGQAVRELAGAGVDLIELGVPFSDPV
CHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEECHHHHHHHHHCCCCEEEECCCCCCCC
ADGPVIQAASKRALAAGVTLPEILELVKSLRSGLAVPLILMSYYNPLLQYGLERLTADLA
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGVDGLIVPDLPLEENPPLRQTLEPAGLALIPLVAPTTPGERLARIAATARGFIYCVSL
HHCCCCEECCCCCCCCCCCHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEEEEE
TGVTGVREGLPPGIDEYLAGVRAVTDLPLGIGFGIGSPDQARLLAPMGDGIIVGSALVDV
CCCHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCEEHHHHHHHH
LYQEGLPAALRLVERLRHAL
HHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA