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The map label for this gene is hepT [H]

Identifier: 83590100

GI number: 83590100

Start: 1293701

End: 1294669

Strand: Reverse

Name: hepT [H]

Synonym: Moth_1252

Alternate gene names: 83590100

Gene position: 1294669-1293701 (Counterclockwise)

Preceding gene: 83590101

Following gene: 83590099

Centisome position: 49.25

GC content: 57.69

Gene sequence:

>969_bases
ATGAAGGAGTTAGCCCTCTGGCAGGAGGTACAAGCCGATTTACAACAGGTAGAGGCCGAACTCTTACGGCAGGTGGACGC
CCCGGACCCGGTTCTTAGCCAGGCCGCCCGCCACCTGGTCCAGGCGGGGGGAAAAAGACTCCGCCCGGCTTTCGCCATCC
TGGCGGCCAGGTGTTGCGGCGCCCCCCTGGAACGCATCCTACCCCTGGCGGTGGCCCTGGAAATGATCCATATGGCCACC
CTGGTCCATGATGACGTTATTGACGCTTCCCCCATCCGGCGGGGACGACCGACGGTCTGGGCCCGGTGGGGCCAGGAGCT
ATCCCTGCATACCGGTGATTATCTCTTTGCCCGTTCCCTGATTTTGGTAGCTACCTATGACGACCCGCGAATACCCTCGG
TCCTGGCCAGTGTCAGTGTGAAGATGGTACAAGGGGAAATCCAGCAAATGGCAGCGGCCTTCGACCTGGATATTACCCTA
CGGGATTACCTGGATCGCATTTACCGCAAAACCGCCTTGTTGATAGCCGCTAGTTGTGAGCTGGGAGCTATTGCCGCCGG
GGCGGACACAGCGACTATACGCCACCTGCGCTATTATGGTCGCAACCTGGGTCTGGCTTTCCAGATTACCGATGACGTAC
TGGATATGGTAGCCGACCCGGAACAGCTGGGTAAGCCCATTGGCGGTGACCTGCGTCAGGGGGTTATTACCCTGCCGGCC
ATTTATGCCCTGCAGGCCAGCCCCAAAAAACAAAAACTCATCCATCTCCTGGGGAAGAGGGATAAAACCCAGGCGGAGAT
CCAGGAAGCAATCCAGCTTATCAAGGATTGTGGCGGTATCAAGTATGCCCTGGATATAGCTGAGGGGTATTTGGAAAGGG
CCAGAAAGCAGGCATCCTACCTGCCTCCGGGTGTGGCCAGGGATACCCTCACAAGCCTGACGTATTATATAAGGACGCGT
GGTTTTTAA

Upstream 100 bases:

>100_bases
CCTGTTCTCTCTAAATAGTAAAGACACGCCACGCGATGCTAAAGAGCGTGTATGGGGAAAAATACTCGGCAAGAAAAGCT
ACAGGTGGTATAATGAAATT

Downstream 100 bases:

>100_bases
TGGGCTTTTACCCACTGGTTATTGACCTGACTGACCGCCCCTGCCTGGTGATTGGAGGCGGTACTGTTAGTGAACGTAAG
GTTTTGAATTTACTGGAAGC

Product: trans-hexaprenyltranstransferase

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKELALWQEVQADLQQVEAELLRQVDAPDPVLSQAARHLVQAGGKRLRPAFAILAARCCGAPLERILPLAVALEMIHMAT
LVHDDVIDASPIRRGRPTVWARWGQELSLHTGDYLFARSLILVATYDDPRIPSVLASVSVKMVQGEIQQMAAAFDLDITL
RDYLDRIYRKTALLIAASCELGAIAAGADTATIRHLRYYGRNLGLAFQITDDVLDMVADPEQLGKPIGGDLRQGVITLPA
IYALQASPKKQKLIHLLGKRDKTQAEIQEAIQLIKDCGGIKYALDIAEGYLERARKQASYLPPGVARDTLTSLTYYIRTR
GF

Sequences:

>Translated_322_residues
MKELALWQEVQADLQQVEAELLRQVDAPDPVLSQAARHLVQAGGKRLRPAFAILAARCCGAPLERILPLAVALEMIHMAT
LVHDDVIDASPIRRGRPTVWARWGQELSLHTGDYLFARSLILVATYDDPRIPSVLASVSVKMVQGEIQQMAAAFDLDITL
RDYLDRIYRKTALLIAASCELGAIAAGADTATIRHLRYYGRNLGLAFQITDDVLDMVADPEQLGKPIGGDLRQGVITLPA
IYALQASPKKQKLIHLLGKRDKTQAEIQEAIQLIKDCGGIKYALDIAEGYLERARKQASYLPPGVARDTLTSLTYYIRTR
GF
>Mature_322_residues
MKELALWQEVQADLQQVEAELLRQVDAPDPVLSQAARHLVQAGGKRLRPAFAILAARCCGAPLERILPLAVALEMIHMAT
LVHDDVIDASPIRRGRPTVWARWGQELSLHTGDYLFARSLILVATYDDPRIPSVLASVSVKMVQGEIQQMAAAFDLDITL
RDYLDRIYRKTALLIAASCELGAIAAGADTATIRHLRYYGRNLGLAFQITDDVLDMVADPEQLGKPIGGDLRQGVITLPA
IYALQASPKKQKLIHLLGKRDKTQAEIQEAIQLIKDCGGIKYALDIAEGYLERARKQASYLPPGVARDTLTSLTYYIRTR
GF

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=321, Percent_Identity=30.8411214953271, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI4758430, Length=276, Percent_Identity=23.5507246376812, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI83700220, Length=276, Percent_Identity=23.5507246376812, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1789578, Length=304, Percent_Identity=33.2236842105263, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1786623, Length=267, Percent_Identity=32.9588014981273, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17505681, Length=302, Percent_Identity=32.1192052980132, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6319475, Length=304, Percent_Identity=30.9210526315789, Blast_Score=141, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6325188, Length=308, Percent_Identity=22.0779220779221, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24651612, Length=273, Percent_Identity=33.3333333333333, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI281365769, Length=287, Percent_Identity=23.6933797909408, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24660002, Length=287, Percent_Identity=23.6933797909408, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 35548; Mature: 35548

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELALWQEVQADLQQVEAELLRQVDAPDPVLSQAARHLVQAGGKRLRPAFAILAARCCG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
APLERILPLAVALEMIHMATLVHDDVIDASPIRRGRPTVWARWGQELSLHTGDYLFARSL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCEECCCCHHHHHHHE
ILVATYDDPRIPSVLASVSVKMVQGEIQQMAAAFDLDITLRDYLDRIYRKTALLIAASCE
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCC
LGAIAAGADTATIRHLRYYGRNLGLAFQITDDVLDMVADPEQLGKPIGGDLRQGVITLPA
CCCEECCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCHHHHCCCCCCHHHHCHHHHHH
IYALQASPKKQKLIHLLGKRDKTQAEIQEAIQLIKDCGGIKYALDIAEGYLERARKQASY
HHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
LPPGVARDTLTSLTYYIRTRGF
CCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKELALWQEVQADLQQVEAELLRQVDAPDPVLSQAARHLVQAGGKRLRPAFAILAARCCG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
APLERILPLAVALEMIHMATLVHDDVIDASPIRRGRPTVWARWGQELSLHTGDYLFARSL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCEECCCCHHHHHHHE
ILVATYDDPRIPSVLASVSVKMVQGEIQQMAAAFDLDITLRDYLDRIYRKTALLIAASCE
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCC
LGAIAAGADTATIRHLRYYGRNLGLAFQITDDVLDMVADPEQLGKPIGGDLRQGVITLPA
CCCEECCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCHHHHCCCCCCHHHHCHHHHHH
IYALQASPKKQKLIHLLGKRDKTQAEIQEAIQLIKDCGGIKYALDIAEGYLERARKQASY
HHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
LPPGVARDTLTSLTYYIRTRGF
CCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]