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The map label for this gene is actP [H]

Identifier: 83313432

GI number: 83313432

Start: 4738470

End: 4740134

Strand: Reverse

Name: actP [H]

Synonym: amb4333

Alternate gene names: 83313432

Gene position: 4740134-4738470 (Counterclockwise)

Preceding gene: 83313438

Following gene: 83313430

Centisome position: 95.43

GC content: 67.15

Gene sequence:

>1665_bases
ATGTCCCACTTCCTCCGCCTCGGCGTTCTGTCCCTGATGCTGCTGGCCCCGTCCCTGCCGGCGCTGGCCGCCGGCGCCGA
TCTCGGCCAGGCTGCCCGGCAGGCTACCAACTGGCACGCCATCCTGATGTTCGTGGGCTTCGTCCTGCTGACCCTGGGCA
TTACCTGGTGGGCCTCCAAACGCACGAAATCGGCGGCGGACTTCTATACGGCCGGGGGCGGTATCACCGGCTTTCAGAAC
GGGCTGGCCATCGCCGGTGACTTCATGTCGGCGGCATCCTTCCTGGGGGTGACCGCCCTGCTCTACGGCACCGGCCTGGA
CGGCATGGTTTATGCCGTGGGCGTGGTGGTGGGCTGGCCGCTGATGCTGTTCCTGATCGCAGAGCCGCTGCGCAACCTCG
GCAAGTACACCTTCGCCGACGTGGTGGCGTATCGTCTGGCCAAGGTGCCGGTGCGGACCTATGCGGCGTTCAGCTCGCTG
ACCGTGGTGGTGTTCTACCTGATCGCCCAGATGGTCGGCGCCGGGCAGCTGATCAAGCTGCTGTTCGGCATGGACTACCT
GTACGCCCTGTTCCTGGTGGGCGGGCTGATGATGATCTACGTCACCTTCGGCGGCATGGCCGCCACCACCTGGGTGCAGA
TCATCAAGGCGGTGCTGCTGCTGTCGGGCGCCACCTTCATGGCGGGGGCGGTGCTGTCCCGCTTCGGCTTCTCGCCCGAG
GCCATGTTCGCCAAGGCCGTTCAGGTCAAGGGCTCCAACGCCATCATGTCGCCGGGCCTGCTGTTCAAGGACCCCATCGA
CACCATTTCCCTGGCCATGGCGCTGGCCTTCGGCACCGCCGGCCTGCCTCATATCCTGATGCGCTTCTTCACGGTGCCCG
ACGCCAAGGAGGCACGCAAATCGGTGTTCTACGCCACCGCTTTCATCGGCTTCTTCTATGTGCTGGCGGTGGTGATCGGC
ATCGGCGCCATCGCCCTGGTGGCCACCGACCCGACCTATCTGGCCGACGGCAAGGCGCTGAAGGGCGGCGGCAACATGGC
GGCCGTGTGGCTGGCCCATGCGGTGGGCGGCGATTTGTTCCTGGGCTTCATCTCGGCGGTGGCCTTCGCCACCATCCTGG
CCGTGGTGGCGGGGCTGACCCTGGCGGGCGCCTCGGCCATTTCCCACGATCTCTACGCCAACGTCTTCGCCCGCGGCCAC
GCCAAGGAGGAGACCGAACTGCGCATCTCGCGGCTGGCCAGTCTGGCGCTCGGCGTGATCGCCATCATCCTGGGCATGCT
GTTCGAGAAGCAGAACATCGCCTATCTGGCCGGTCTGACCCTGGCCATCGCCGCCTCGGCCAATTTCCCGCTGCTGCTGC
TGTCCATGCTGTGGCCGGGCCTGACGTCGCGCGGAGCCATCCTGGGCGGCGTTGCCGGGCTGGTCTCGGCGGTGGTGCTG
ACCGTGCTGGGGCCGGCGGTGTGGAAAGCCGTGCTGGGCAACCCCCAGCCCATCTTCCCCTGGGGCAATCCCGCCCTGTT
CTCGGTGGCGGCGGGGTTCGCCGCCACCTGGTTCTTCTCGGTCACCGACGGCAGCGAGCGGGCGGTGCGGGAGAAGGCCG
AGTTTAATGCCCAGTTCGTCCGTTCGCAGACCGGGCTGGGGGCGGAAGGAGTCTCGGCTCACTGA

Upstream 100 bases:

>100_bases
GATGGCTGTTCGGGAGAGGCGGCGCGTAAAGCTTGCGCGGGAGGAATGAAATAAGTAAACAGGTACCAAAATACCATAAT
TAGCCCGGAGAGGCCGTCCC

Downstream 100 bases:

>100_bases
TCCGTCCCCCGGGCGGCCGGGGTCAGCGGCCCTTGTCGCTTCTCAGCACGTAAAGGCCGGACGCCATCACCACCAGGGCG
CCGGCCAGCGTGTTGAGAGT

Product: symporter

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MSHFLRLGVLSLMLLAPSLPALAAGADLGQAARQATNWHAILMFVGFVLLTLGITWWASKRTKSAADFYTAGGGITGFQN
GLAIAGDFMSAASFLGVTALLYGTGLDGMVYAVGVVVGWPLMLFLIAEPLRNLGKYTFADVVAYRLAKVPVRTYAAFSSL
TVVVFYLIAQMVGAGQLIKLLFGMDYLYALFLVGGLMMIYVTFGGMAATTWVQIIKAVLLLSGATFMAGAVLSRFGFSPE
AMFAKAVQVKGSNAIMSPGLLFKDPIDTISLAMALAFGTAGLPHILMRFFTVPDAKEARKSVFYATAFIGFFYVLAVVIG
IGAIALVATDPTYLADGKALKGGGNMAAVWLAHAVGGDLFLGFISAVAFATILAVVAGLTLAGASAISHDLYANVFARGH
AKEETELRISRLASLALGVIAIILGMLFEKQNIAYLAGLTLAIAASANFPLLLLSMLWPGLTSRGAILGGVAGLVSAVVL
TVLGPAVWKAVLGNPQPIFPWGNPALFSVAAGFAATWFFSVTDGSERAVREKAEFNAQFVRSQTGLGAEGVSAH

Sequences:

>Translated_554_residues
MSHFLRLGVLSLMLLAPSLPALAAGADLGQAARQATNWHAILMFVGFVLLTLGITWWASKRTKSAADFYTAGGGITGFQN
GLAIAGDFMSAASFLGVTALLYGTGLDGMVYAVGVVVGWPLMLFLIAEPLRNLGKYTFADVVAYRLAKVPVRTYAAFSSL
TVVVFYLIAQMVGAGQLIKLLFGMDYLYALFLVGGLMMIYVTFGGMAATTWVQIIKAVLLLSGATFMAGAVLSRFGFSPE
AMFAKAVQVKGSNAIMSPGLLFKDPIDTISLAMALAFGTAGLPHILMRFFTVPDAKEARKSVFYATAFIGFFYVLAVVIG
IGAIALVATDPTYLADGKALKGGGNMAAVWLAHAVGGDLFLGFISAVAFATILAVVAGLTLAGASAISHDLYANVFARGH
AKEETELRISRLASLALGVIAIILGMLFEKQNIAYLAGLTLAIAASANFPLLLLSMLWPGLTSRGAILGGVAGLVSAVVL
TVLGPAVWKAVLGNPQPIFPWGNPALFSVAAGFAATWFFSVTDGSERAVREKAEFNAQFVRSQTGLGAEGVSAH
>Mature_553_residues
SHFLRLGVLSLMLLAPSLPALAAGADLGQAARQATNWHAILMFVGFVLLTLGITWWASKRTKSAADFYTAGGGITGFQNG
LAIAGDFMSAASFLGVTALLYGTGLDGMVYAVGVVVGWPLMLFLIAEPLRNLGKYTFADVVAYRLAKVPVRTYAAFSSLT
VVVFYLIAQMVGAGQLIKLLFGMDYLYALFLVGGLMMIYVTFGGMAATTWVQIIKAVLLLSGATFMAGAVLSRFGFSPEA
MFAKAVQVKGSNAIMSPGLLFKDPIDTISLAMALAFGTAGLPHILMRFFTVPDAKEARKSVFYATAFIGFFYVLAVVIGI
GAIALVATDPTYLADGKALKGGGNMAAVWLAHAVGGDLFLGFISAVAFATILAVVAGLTLAGASAISHDLYANVFARGHA
KEETELRISRLASLALGVIAIILGMLFEKQNIAYLAGLTLAIAASANFPLLLLSMLWPGLTSRGAILGGVAGLVSAVVLT
VLGPAVWKAVLGNPQPIFPWGNPALFSVAAGFAATWFFSVTDGSERAVREKAEFNAQFVRSQTGLGAEGVSAH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=528, Percent_Identity=22.9166666666667, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1790503, Length=544, Percent_Identity=63.7867647058823, Blast_Score=670, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=442, Percent_Identity=26.4705882352941, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 57976; Mature: 57845

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCCCCCC
>Mature Secondary Structure 
SHFLRLGVLSLMLLAPSLPALAAGADLGQAARQATNWHAILMFVGFVLLTLGITWWASK
CHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC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HHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA