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The map label for this gene is 83313344

Identifier: 83313344

GI number: 83313344

Start: 4653903

End: 4656329

Strand: Reverse

Name: 83313344

Synonym: amb4245

Alternate gene names: NA

Gene position: 4656329-4653903 (Counterclockwise)

Preceding gene: 83313345

Following gene: 83313342

Centisome position: 93.74

GC content: 71.03

Gene sequence:

>2427_bases
ATGACCCGCATCCTTGCCGTCCTCGGCCCCACCAATACCGGCAAGACCCACTTCGCCATGGAGCGCATGCTGGCCCATGC
CAGCGGCATGATCGGCTTTCCGCTGCGCCTGCTGGCGCGGGAAAACTACGACCGCATGGTGAAGATCAAGGGTGCCGCCA
ACGTGGCGCTGATCACCGGCGAAGAGAAGATCATCCCGTCCCATGCGCGCTGGCTGGTCTGCACGGTGGAATCCATGCCG
CTGGACCGCCGGGTGGCGTTCCTGGCGGTGGACGAGATCCAGCTTTGCGCCGATCCCGAGCGCGGCCACATCTTCACCGA
CCGCCTGCTGCATGCCCGGGGCGAGTCCGAGACCCTGTTCCTGGGCGCCGAGACCATCCGGCCGCTGATCCGCCGTCTGG
TGCCCGGCGTCGAGTTCATGAGCCGGCCGCGCTTTTCCCAGCTCACCCATGTGGGGGCGAAGAAGCTGGGCCGCCTGCCG
CCGCGCTCGGTGCTGGTGGCCTTCTCGGCGGCCGAGGTCTACGCCATGGCCGAATTCGTCCGCCGTTCTCGGGGCGGGGC
GGCGGTGGTGCTGGGCGCGCTGAGCCCTCGTACCCGCAACGCCCAGGTGGGAATGTATCAGGCGGGGGAGGTGGATTACA
TCGTCGCCACCGACGCTATCGGCATGGGGCTCAACATGGACGTGGACCATGTGGCCTTCGCCGCCCTGCGCAAGTTCGAC
GGCAGGGCGCCGCGCCCCCTGGAGCCCACCGAGATCGCCCAGATCGCCGGCCGCGCCGGGCGGCACATGAACGACGGCAC
CTTCGGCACCACCATGGACGCGGGGACCATCGCCTCGGAGATCGTCGAGCAGGTGGAGAATCACCGCTTCGATCCCCTGA
AGACCCTCTACTGGCGCAATGCCGACCTGCGCTTCGCCTCCGTTGCCGCCCTGCTGTCCAGCCTGGACCGGCCGCCGGAC
AAGCCCGGCCTGCTGCGGGCGCGCGACGCCGACGACCAGTTGGCCCTGGCCGCCCTGGCCCAGGACGAGGACATCATCCG
TCTGGCCAGCCATCCCGAGCGGGTGAAGCTGCTGTGGGAGGTTTGCCGCGTCCCCGACTTCCGCAAGGTGATGGATGAAT
CCCATACCCGGCTGCTGGGCCGCATCTTCCGCTATCTGGCCGCTCCCTCGGGTCGCCTGCCCACCGATTGGCTGGCCGAG
AACATTCGGCGCATCGACCGCACCGACGGCGAGCTGGACACCATCGTTCAGCGCATCGCCAACATCCGCACCTGGACCTA
TGTGTCGCACCGCAGCGACTGGGTGCCCGACTCCGCCCATTGGCAGGAGGTGACCCGCGGCGTCGAGGACCGCCTGTCCG
ATGCGCTGCACCAGCGGCTCACCAACCGCTTCGTCGACAAGCGCACCGCCGTGCTGGTGCGCCGCCTGCGCGACGGCGGC
GCCATGGATTCCGAGATCGGACCCGAGGGCGAGGTGCGGGTGGAGGGCGAGTATGTGGGCCGTCTGGCCGGGTTCCGCTT
CCAGGTGGATCAGGCGGACAATTCGGCGGCCGGACGCACCATGCTGGCCGCCGCCCTGCGGGCCCTGGCGCCCGAGGTGG
ACCGCCGCCTGACCCAGGCCCTGGCCGACCCGCCCGAGGCCTTCGAGCTGGGGCCGGACGGCCTTTTCTGGCGCGGCGAG
CCCCTGGCCTGCCTGTCCGCCGGGGCCGATGCCCTGCACCCCAAGGTGGAGGCCCCCGACGGCGACCTGCTGCCGCCCAA
GGGGCGCGAACGCCTGCGCCAGAGGCTGGCGGACGTGGTCCGGAGCTGGCTGGCCAACCGGTTGCCCTCCCTGGTTCGCC
TGGGTCAGGCGCCGTTGACCGGCGGGGCGCGGGGGCTGGCGCATCAATTGGCCGAGGGGCTGGGCTCCATGCCCTGTGAC
GAGGCCCTGGTCCGCACCCTGACCAAGGACGATTCCCTGGCCCTGGCCCGCCTGGATATCCGGGTCGGGCGGCACGGCCT
GTATATCCCGGCCCTGCTCAAGCCCAAGGCGCAAGGCTTGCGCGCCCTGCTGTGGTCCATCCATGCGGGAACCTCCGCCC
CGGACATCCCCGGCCCCCGCCCGGCGGTGCCCTTGGCCGATGGCGTGCCGCCGGCCTTCTACGAGGCGGTGGGCTATGGC
GTGCTGGGCAAGGTGGCGGTGCGCCGCGACGTCCTGGAACGCTTCGCCGCCCTGGCCCGCGCCGCCGCCCATGACGGGGT
CTTCCAGCCCAGCCACGACATGCACTCGGCCCTGGGCCTGGGACCGGCGGCGACGGAAAGCGTGCTGGAGGCGCTGGGCT
ATGTGCGGGCGGGCGACGGGTTCAGGACGGGCCGGAAGCCCCGGCGCAAGGTCCGGCCGGAACAGCCTTCGGATTCACCG
TTCGCGGTGCTGAAGGGGCGGCGCTGA

Upstream 100 bases:

>100_bases
CTTCCGGACCTGACCGGGTTGGCGACGGGTCCGTCCATGCCGATCTCCCGGGGCGGACCATAAGAGCAACCGGCAGTCCT
TTGCAAGGCCGATTCGAGTC

Downstream 100 bases:

>100_bases
GGATTGGGCTGCCGCCCAAACCCGCTTGGAGGCATGCCTCCAAACCTCCCTTTGGTTTATCAATAATCACGCAAACAGAT
ACGGCACGAAAGACCGGTTG

Product: superfamily II DNA/RNA helicase

Products: NA

Alternate protein names: Helicase Domain Protein; Helicase; Helicase-Like; Helicase Conserved C-Terminal Domain Protein; ATP-Dependent Helicase; ATP-Dependent RNA Helicase; ATP-Dependent DNA Helicase; ATP-Dependent DNA Helicase Protein; MgpS ATP-Dependent Helicase; RNA Helicase; Superfamily II DNA/RNA Helicase; Helicase-Like Protein; Superfamily II DNA And RNA Helicase; ATP-Dependent RNA And DNA Helicase; ATP Dependent RNA Helicase; Adenosinetriphosphatase; RNA Helicase RhrA; ATP-Dependent Helicase MgpS; ATP-Dependent RNA Helicase Superfamily II; Helicase C-Terminal Domain Protein; DNA Helicase; ATP-Dependent DNA And RNA Helicase Protein

Number of amino acids: Translated: 808; Mature: 807

Protein sequence:

>808_residues
MTRILAVLGPTNTGKTHFAMERMLAHASGMIGFPLRLLARENYDRMVKIKGAANVALITGEEKIIPSHARWLVCTVESMP
LDRRVAFLAVDEIQLCADPERGHIFTDRLLHARGESETLFLGAETIRPLIRRLVPGVEFMSRPRFSQLTHVGAKKLGRLP
PRSVLVAFSAAEVYAMAEFVRRSRGGAAVVLGALSPRTRNAQVGMYQAGEVDYIVATDAIGMGLNMDVDHVAFAALRKFD
GRAPRPLEPTEIAQIAGRAGRHMNDGTFGTTMDAGTIASEIVEQVENHRFDPLKTLYWRNADLRFASVAALLSSLDRPPD
KPGLLRARDADDQLALAALAQDEDIIRLASHPERVKLLWEVCRVPDFRKVMDESHTRLLGRIFRYLAAPSGRLPTDWLAE
NIRRIDRTDGELDTIVQRIANIRTWTYVSHRSDWVPDSAHWQEVTRGVEDRLSDALHQRLTNRFVDKRTAVLVRRLRDGG
AMDSEIGPEGEVRVEGEYVGRLAGFRFQVDQADNSAAGRTMLAAALRALAPEVDRRLTQALADPPEAFELGPDGLFWRGE
PLACLSAGADALHPKVEAPDGDLLPPKGRERLRQRLADVVRSWLANRLPSLVRLGQAPLTGGARGLAHQLAEGLGSMPCD
EALVRTLTKDDSLALARLDIRVGRHGLYIPALLKPKAQGLRALLWSIHAGTSAPDIPGPRPAVPLADGVPPAFYEAVGYG
VLGKVAVRRDVLERFAALARAAAHDGVFQPSHDMHSALGLGPAATESVLEALGYVRAGDGFRTGRKPRRKVRPEQPSDSP
FAVLKGRR

Sequences:

>Translated_808_residues
MTRILAVLGPTNTGKTHFAMERMLAHASGMIGFPLRLLARENYDRMVKIKGAANVALITGEEKIIPSHARWLVCTVESMP
LDRRVAFLAVDEIQLCADPERGHIFTDRLLHARGESETLFLGAETIRPLIRRLVPGVEFMSRPRFSQLTHVGAKKLGRLP
PRSVLVAFSAAEVYAMAEFVRRSRGGAAVVLGALSPRTRNAQVGMYQAGEVDYIVATDAIGMGLNMDVDHVAFAALRKFD
GRAPRPLEPTEIAQIAGRAGRHMNDGTFGTTMDAGTIASEIVEQVENHRFDPLKTLYWRNADLRFASVAALLSSLDRPPD
KPGLLRARDADDQLALAALAQDEDIIRLASHPERVKLLWEVCRVPDFRKVMDESHTRLLGRIFRYLAAPSGRLPTDWLAE
NIRRIDRTDGELDTIVQRIANIRTWTYVSHRSDWVPDSAHWQEVTRGVEDRLSDALHQRLTNRFVDKRTAVLVRRLRDGG
AMDSEIGPEGEVRVEGEYVGRLAGFRFQVDQADNSAAGRTMLAAALRALAPEVDRRLTQALADPPEAFELGPDGLFWRGE
PLACLSAGADALHPKVEAPDGDLLPPKGRERLRQRLADVVRSWLANRLPSLVRLGQAPLTGGARGLAHQLAEGLGSMPCD
EALVRTLTKDDSLALARLDIRVGRHGLYIPALLKPKAQGLRALLWSIHAGTSAPDIPGPRPAVPLADGVPPAFYEAVGYG
VLGKVAVRRDVLERFAALARAAAHDGVFQPSHDMHSALGLGPAATESVLEALGYVRAGDGFRTGRKPRRKVRPEQPSDSP
FAVLKGRR
>Mature_807_residues
TRILAVLGPTNTGKTHFAMERMLAHASGMIGFPLRLLARENYDRMVKIKGAANVALITGEEKIIPSHARWLVCTVESMPL
DRRVAFLAVDEIQLCADPERGHIFTDRLLHARGESETLFLGAETIRPLIRRLVPGVEFMSRPRFSQLTHVGAKKLGRLPP
RSVLVAFSAAEVYAMAEFVRRSRGGAAVVLGALSPRTRNAQVGMYQAGEVDYIVATDAIGMGLNMDVDHVAFAALRKFDG
RAPRPLEPTEIAQIAGRAGRHMNDGTFGTTMDAGTIASEIVEQVENHRFDPLKTLYWRNADLRFASVAALLSSLDRPPDK
PGLLRARDADDQLALAALAQDEDIIRLASHPERVKLLWEVCRVPDFRKVMDESHTRLLGRIFRYLAAPSGRLPTDWLAEN
IRRIDRTDGELDTIVQRIANIRTWTYVSHRSDWVPDSAHWQEVTRGVEDRLSDALHQRLTNRFVDKRTAVLVRRLRDGGA
MDSEIGPEGEVRVEGEYVGRLAGFRFQVDQADNSAAGRTMLAAALRALAPEVDRRLTQALADPPEAFELGPDGLFWRGEP
LACLSAGADALHPKVEAPDGDLLPPKGRERLRQRLADVVRSWLANRLPSLVRLGQAPLTGGARGLAHQLAEGLGSMPCDE
ALVRTLTKDDSLALARLDIRVGRHGLYIPALLKPKAQGLRALLWSIHAGTSAPDIPGPRPAVPLADGVPPAFYEAVGYGV
LGKVAVRRDVLERFAALARAAAHDGVFQPSHDMHSALGLGPAATESVLEALGYVRAGDGFRTGRKPRRKVRPEQPSDSPF
AVLKGRR

Specific function: Unknown

COG id: COG0513

COG function: function code LKJ; Superfamily II DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543667, Length=312, Percent_Identity=30.1282051282051, Blast_Score=117, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI115532784, Length=488, Percent_Identity=25.4098360655738, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115532782, Length=488, Percent_Identity=25.4098360655738, Blast_Score=106, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6325228, Length=278, Percent_Identity=33.0935251798561, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI221329989, Length=279, Percent_Identity=32.258064516129, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 88693; Mature: 88562

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRILAVLGPTNTGKTHFAMERMLAHASGMIGFPLRLLARENYDRMVKIKGAANVALITG
CCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCEEEEEC
EEKIIPSHARWLVCTVESMPLDRRVAFLAVDEIQLCADPERGHIFTDRLLHARGESETLF
CCCCCCCCCCEEEEEECCCCCCCEEEEEEECHHHHHCCCCCCCCHHHHHHHHCCCCCEEE
LGAETIRPLIRRLVPGVEFMSRPRFSQLTHVGAKKLGRLPPRSVLVAFSAAEVYAMAEFV
EEHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHHHH
RRSRGGAAVVLGALSPRTRNAQVGMYQAGEVDYIVATDAIGMGLNMDVDHVAFAALRKFD
HHCCCCCEEEEECCCCCCCCCEECEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHC
GRAPRPLEPTEIAQIAGRAGRHMNDGTFGTTMDAGTIASEIVEQVENHRFDPLKTLYWRN
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCC
ADLRFASVAALLSSLDRPPDKPGLLRARDADDQLALAALAQDEDIIRLASHPERVKLLWE
CCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHCCCCHHHHHCCHHHHHHHHH
VCRVPDFRKVMDESHTRLLGRIFRYLAAPSGRLPTDWLAENIRRIDRTDGELDTIVQRIA
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
NIRTWTYVSHRSDWVPDSAHWQEVTRGVEDRLSDALHQRLTNRFVDKRTAVLVRRLRDGG
CCHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AMDSEIGPEGEVRVEGEYVGRLAGFRFQVDQADNSAAGRTMLAAALRALAPEVDRRLTQA
CCCCCCCCCCCEEECHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LADPPEAFELGPDGLFWRGEPLACLSAGADALHPKVEAPDGDLLPPKGRERLRQRLADVV
HCCCCHHHCCCCCCCEECCCCCHHHHCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RSWLANRLPSLVRLGQAPLTGGARGLAHQLAEGLGSMPCDEALVRTLTKDDSLALARLDI
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEH
RVGRHGLYIPALLKPKAQGLRALLWSIHAGTSAPDIPGPRPAVPLADGVPPAFYEAVGYG
EECCCCEEECHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
VLGKVAVRRDVLERFAALARAAAHDGVFQPSHDMHSALGLGPAATESVLEALGYVRAGDG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCEECCCC
FRTGRKPRRKVRPEQPSDSPFAVLKGRR
CCCCCCCHHHCCCCCCCCCCEEECCCCC
>Mature Secondary Structure 
TRILAVLGPTNTGKTHFAMERMLAHASGMIGFPLRLLARENYDRMVKIKGAANVALITG
CEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCEEEEEC
EEKIIPSHARWLVCTVESMPLDRRVAFLAVDEIQLCADPERGHIFTDRLLHARGESETLF
CCCCCCCCCCEEEEEECCCCCCCEEEEEEECHHHHHCCCCCCCCHHHHHHHHCCCCCEEE
LGAETIRPLIRRLVPGVEFMSRPRFSQLTHVGAKKLGRLPPRSVLVAFSAAEVYAMAEFV
EEHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHHHH
RRSRGGAAVVLGALSPRTRNAQVGMYQAGEVDYIVATDAIGMGLNMDVDHVAFAALRKFD
HHCCCCCEEEEECCCCCCCCCEECEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHC
GRAPRPLEPTEIAQIAGRAGRHMNDGTFGTTMDAGTIASEIVEQVENHRFDPLKTLYWRN
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCC
ADLRFASVAALLSSLDRPPDKPGLLRARDADDQLALAALAQDEDIIRLASHPERVKLLWE
CCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHCCCCHHHHHCCHHHHHHHHH
VCRVPDFRKVMDESHTRLLGRIFRYLAAPSGRLPTDWLAENIRRIDRTDGELDTIVQRIA
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
NIRTWTYVSHRSDWVPDSAHWQEVTRGVEDRLSDALHQRLTNRFVDKRTAVLVRRLRDGG
CCHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AMDSEIGPEGEVRVEGEYVGRLAGFRFQVDQADNSAAGRTMLAAALRALAPEVDRRLTQA
CCCCCCCCCCCEEECHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LADPPEAFELGPDGLFWRGEPLACLSAGADALHPKVEAPDGDLLPPKGRERLRQRLADVV
HCCCCHHHCCCCCCCEECCCCCHHHHCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RSWLANRLPSLVRLGQAPLTGGARGLAHQLAEGLGSMPCDEALVRTLTKDDSLALARLDI
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEH
RVGRHGLYIPALLKPKAQGLRALLWSIHAGTSAPDIPGPRPAVPLADGVPPAFYEAVGYG
EECCCCEEECHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
VLGKVAVRRDVLERFAALARAAAHDGVFQPSHDMHSALGLGPAATESVLEALGYVRAGDG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCEECCCC
FRTGRKPRRKVRPEQPSDSPFAVLKGRR
CCCCCCCHHHCCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA