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The map label for this gene is cycW [H]

Identifier: 83313278

GI number: 83313278

Start: 4592269

End: 4592934

Strand: Reverse

Name: cycW [H]

Synonym: amb4179

Alternate gene names: 83313278

Gene position: 4592934-4592269 (Counterclockwise)

Preceding gene: 83313279

Following gene: 83313272

Centisome position: 92.47

GC content: 70.42

Gene sequence:

>666_bases
ATGAACCGCTTTGTCGAGGTGGTTCGCCGCGACCTGCGTCTGGCCCTGCGCCAGGGCTCGGACAGCGTCATGGTGGTGAC
CTTCTTCGTGCTGACCGTGGTGCTGTTTCCCTTCGGCATCGGGCCGGAAGCCAATGTGCTGGAGCGCGTGGCGGCCGGGG
TGCTGATGGTCACCGCTTTGCTGGCCTCCATGCTGTCGCTGGACCGGCTGTTCCAGGCCGATTACGAGGATGGCTCGCTG
GAGCTGCTGGTGCTGACCCCGGCGCCCCTGGGCGTGGTGGTCGCGGCCAAGATGCTGGCCCACTGGCTGACCACCGGCCT
GCCGCTGATGGTGGCCGCGCCGGTGCTGGCCGTTCTGCTGCACATGCACGAGGACGGGTTCCTGACCCTGCTGGCCGCCA
TGGCGCTGGGCACTCCGGTGCTGTCCCTGGTGGGCGGCATCGGCGCCGCCTTGGTGCTGGGGGCAAGGCGGGGCGGGGTG
CTGCTGTCGCTGCTGATCCTGCCGCTGTACGTCCCGGTGCTGATCTTCGGGGTGGGGGCCATCGATGCCGCCGTGCAGGG
CCTGTCGGCCAAGCCCCATCTGCTGATCCTGTCGGCCATGCTGGCCGCCGCCCTGGTCCTCGCCCCCTGGGCCAGCGCCG
CGGCGCTGCGGCAGGCGCTGGAATAG

Upstream 100 bases:

>100_bases
CGGCGGGCGGCATGGTGGTGCTGTCCACCCATGCCGACATCAACATGCCGGGCGCCCAGGAACTGCATCTGGATCAATTC
GCCGTGGCGGAGGAGCTTCC

Downstream 100 bases:

>100_bases
AGCGTTAAGCGGGTTGGGGAACGGCTCCACTTCGGGGGCGTTTGCCCCCGATCCCCCAATCGGGAAGCATGGCTTCCCGA
ACCCTTCAGCTTTTCAGACC

Product: ABC-type transport system involved in cytochrome c biogenesis, permease component

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MNRFVEVVRRDLRLALRQGSDSVMVVTFFVLTVVLFPFGIGPEANVLERVAAGVLMVTALLASMLSLDRLFQADYEDGSL
ELLVLTPAPLGVVVAAKMLAHWLTTGLPLMVAAPVLAVLLHMHEDGFLTLLAAMALGTPVLSLVGGIGAALVLGARRGGV
LLSLLILPLYVPVLIFGVGAIDAAVQGLSAKPHLLILSAMLAAALVLAPWASAAALRQALE

Sequences:

>Translated_221_residues
MNRFVEVVRRDLRLALRQGSDSVMVVTFFVLTVVLFPFGIGPEANVLERVAAGVLMVTALLASMLSLDRLFQADYEDGSL
ELLVLTPAPLGVVVAAKMLAHWLTTGLPLMVAAPVLAVLLHMHEDGFLTLLAAMALGTPVLSLVGGIGAALVLGARRGGV
LLSLLILPLYVPVLIFGVGAIDAAVQGLSAKPHLLILSAMLAAALVLAPWASAAALRQALE
>Mature_221_residues
MNRFVEVVRRDLRLALRQGSDSVMVVTFFVLTVVLFPFGIGPEANVLERVAAGVLMVTALLASMLSLDRLFQADYEDGSL
ELLVLTPAPLGVVVAAKMLAHWLTTGLPLMVAAPVLAVLLHMHEDGFLTLLAAMALGTPVLSLVGGIGAALVLGARRGGV
LLSLLILPLYVPVLIFGVGAIDAAVQGLSAKPHLLILSAMLAAALVLAPWASAAALRQALE

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=218, Percent_Identity=46.7889908256881, Blast_Score=151, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 23069; Mature: 23069

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFVEVVRRDLRLALRQGSDSVMVVTFFVLTVVLFPFGIGPEANVLERVAAGVLMVTAL
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LASMLSLDRLFQADYEDGSLELLVLTPAPLGVVVAAKMLAHWLTTGLPLMVAAPVLAVLL
HHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
HMHEDGFLTLLAAMALGTPVLSLVGGIGAALVLGARRGGVLLSLLILPLYVPVLIFGVGA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
IDAAVQGLSAKPHLLILSAMLAAALVLAPWASAAALRQALE
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRFVEVVRRDLRLALRQGSDSVMVVTFFVLTVVLFPFGIGPEANVLERVAAGVLMVTAL
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LASMLSLDRLFQADYEDGSLELLVLTPAPLGVVVAAKMLAHWLTTGLPLMVAAPVLAVLL
HHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
HMHEDGFLTLLAAMALGTPVLSLVGGIGAALVLGARRGGVLLSLLILPLYVPVLIFGVGA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
IDAAVQGLSAKPHLLILSAMLAAALVLAPWASAAALRQALE
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]