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The map label for this gene is argK [C]

Identifier: 83313210

GI number: 83313210

Start: 4515505

End: 4516494

Strand: Reverse

Name: argK [C]

Synonym: amb4111

Alternate gene names: 83313210

Gene position: 4516494-4515505 (Counterclockwise)

Preceding gene: 83313211

Following gene: 83313209

Centisome position: 90.93

GC content: 71.52

Gene sequence:

>990_bases
GTGAGCATTTCCCCCGATCCCAAGGCTCTCAGCCAGGGTGTGCTGGCCGGCGAGCGCCGTGCCCTGGCCCGTGCCATCAC
CCTGATCGAATCCACCCGGCCCGACCACCGCGAGGCGGCCGAGGCGCTGATGCATGAATTGCTGCCCCATACCGGACGGT
CGGTGCGCATCGGCATCACCGGCGTGCCGGGAGCGGGCAAGAGCACCTTCATCGAGAGCTTCGGCCTGCATGTGCTGGAG
ATGGGCAAGAAGCCGGCGGTGCTGGCCGTCGATCCGTCTTCGCCGCGCTCGGGCGGTTCCATCCTGGGCGACAAGACCCG
CATGGAGGACCTGTCCCGCGACGCCCGCGCCTTCATCCGCCCCAGCCCCTCGGGCTGCACCCTGGGCGGCGTGGCGCGCC
GCACCCGCGAGGCCATGCTGGTCTGCGAGGCGGCGGGCTTCGACGTCATCGTGGTGGAAACCGTGGGCGTCGGTCAGTCC
GAGACGGCGGTGGCCGACATGGTCGACATGTTCCTGCTGGTCCTGGTGCCCGGCGGCGGCGACGAGCTGCAGGGCATCAA
GAAGGGCATCGTCGAGCTGGCCGACGCCATCATCGTCAACAAGGCCGACGGCGATCTGGCGGCGGCGGCGGCCCGCGCCG
CCCGGGACTACAAGAACGCCCTGCACCTGCTGGCGCCGGCCTCGCCCCATTGGACCGTGCCGGTGCTGACCTGCTCGGCC
CTGGCGCGGTCGGGCATCGACGAGGTGTGGTCGACCATCGCCACCTACCGCGACACCATGGACAAGGCCGGCGCCCTGGC
CGACCGCCGCGCCGCCCAGGCCCATGCCTGGATGTGGAACGAGGTGTCCGAGACGCTGCTGCAGGCCCTGCGCGACGATC
CCCGGGTCGAACGGATGCTGCCGGATATGGAGCGCGGCGTCGCCGGCGGGCGAATGGCCCCAGGCGCGGCCGCCAGGGCT
CTGGTCCGCACCTTTCGCGGGCAAGGCTGA

Upstream 100 bases:

>100_bases
CCCTGTCGGACGAGGACCGGGCCAAGCTGGTCAGCATGGCCATCCTCACCTTTCTCAACCAGGGCCAAGAGCCCGACGAC
AAGAAGAGATAGCCCGCAAC

Downstream 100 bases:

>100_bases
CGTTACCTAAAGTCACAGGGATGGGCCTTGGCGTATTCCTGATAAACAGGCTATCCTCTGACTTCAGTATGAAGGCGACG
GAATGAACATGCGGACACCG

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSISPDPKALSQGVLAGERRALARAITLIESTRPDHREAAEALMHELLPHTGRSVRIGITGVPGAGKSTFIESFGLHVLE
MGKKPAVLAVDPSSPRSGGSILGDKTRMEDLSRDARAFIRPSPSGCTLGGVARRTREAMLVCEAAGFDVIVVETVGVGQS
ETAVADMVDMFLLVLVPGGGDELQGIKKGIVELADAIIVNKADGDLAAAAARAARDYKNALHLLAPASPHWTVPVLTCSA
LARSGIDEVWSTIATYRDTMDKAGALADRRAAQAHAWMWNEVSETLLQALRDDPRVERMLPDMERGVAGGRMAPGAAARA
LVRTFRGQG

Sequences:

>Translated_329_residues
MSISPDPKALSQGVLAGERRALARAITLIESTRPDHREAAEALMHELLPHTGRSVRIGITGVPGAGKSTFIESFGLHVLE
MGKKPAVLAVDPSSPRSGGSILGDKTRMEDLSRDARAFIRPSPSGCTLGGVARRTREAMLVCEAAGFDVIVVETVGVGQS
ETAVADMVDMFLLVLVPGGGDELQGIKKGIVELADAIIVNKADGDLAAAAARAARDYKNALHLLAPASPHWTVPVLTCSA
LARSGIDEVWSTIATYRDTMDKAGALADRRAAQAHAWMWNEVSETLLQALRDDPRVERMLPDMERGVAGGRMAPGAAARA
LVRTFRGQG
>Mature_328_residues
SISPDPKALSQGVLAGERRALARAITLIESTRPDHREAAEALMHELLPHTGRSVRIGITGVPGAGKSTFIESFGLHVLEM
GKKPAVLAVDPSSPRSGGSILGDKTRMEDLSRDARAFIRPSPSGCTLGGVARRTREAMLVCEAAGFDVIVVETVGVGQSE
TAVADMVDMFLLVLVPGGGDELQGIKKGIVELADAIIVNKADGDLAAAAARAARDYKNALHLLAPASPHWTVPVLTCSAL
ARSGIDEVWSTIATYRDTMDKAGALADRRAAQAHAWMWNEVSETLLQALRDDPRVERMLPDMERGVAGGRMAPGAAARAL
VRTFRGQG

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=329, Percent_Identity=49.8480243161094, Blast_Score=315, Evalue=3e-86,
Organism=Escherichia coli, GI1789285, Length=312, Percent_Identity=47.7564102564103, Blast_Score=299, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI71994271, Length=334, Percent_Identity=42.5149700598802, Blast_Score=288, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI71994275, Length=274, Percent_Identity=44.8905109489051, Blast_Score=266, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 34811; Mature: 34680

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISPDPKALSQGVLAGERRALARAITLIESTRPDHREAAEALMHELLPHTGRSVRIGIT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEE
GVPGAGKSTFIESFGLHVLEMGKKPAVLAVDPSSPRSGGSILGDKTRMEDLSRDARAFIR
ECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
PSPSGCTLGGVARRTREAMLVCEAAGFDVIVVETVGVGQSETAVADMVDMFLLVLVPGGG
CCCCCCCHHHHHHHHHHHHEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCC
DELQGIKKGIVELADAIIVNKADGDLAAAAARAARDYKNALHLLAPASPHWTVPVLTCSA
HHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LARSGIDEVWSTIATYRDTMDKAGALADRRAAQAHAWMWNEVSETLLQALRDDPRVERML
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHC
PDMERGVAGGRMAPGAAARALVRTFRGQG
CHHHHCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SISPDPKALSQGVLAGERRALARAITLIESTRPDHREAAEALMHELLPHTGRSVRIGIT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEE
GVPGAGKSTFIESFGLHVLEMGKKPAVLAVDPSSPRSGGSILGDKTRMEDLSRDARAFIR
ECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
PSPSGCTLGGVARRTREAMLVCEAAGFDVIVVETVGVGQSETAVADMVDMFLLVLVPGGG
CCCCCCCHHHHHHHHHHHHEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCC
DELQGIKKGIVELADAIIVNKADGDLAAAAARAARDYKNALHLLAPASPHWTVPVLTCSA
HHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LARSGIDEVWSTIATYRDTMDKAGALADRRAAQAHAWMWNEVSETLLQALRDDPRVERML
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHC
PDMERGVAGGRMAPGAAARALVRTFRGQG
CHHHHCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]